Clinicopathologic Factors Associated With Occult Lymph Node Metastasis in Patients With Clinically Diagnosed N0 Lung Adenocarcinoma

Annals of Thoracic Surgery

Volumn 101, Issue 5, 2016, Pages 1928-1935

  Moon, Youngkyu ^a   Kim, Kyung Soo ^a   Lee, Kyo Young ^a   Sung, Sook Whan ^a   Kim, Young Kyoon ^a   Park, Jae Kil ^a  

^a The Catholic University of Korea   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; BILOBECTOMY; CANCER PATIENT; CANCER STAGING; CANCER SURGERY; CLINICAL FEATURE; CONTROLLED STUDY; FEMALE; HUMAN; LOBECTOMY; LUNG ADENOCARCINOMA; LUNG RESECTION; LYMPH NODE DISSECTION; LYMPH NODE METASTASIS; LYMPH VESSEL METASTASIS; MAJOR CLINICAL STUDY; MALE; MEDIASTINUM LYMPH NODE; MEDICAL RECORD REVIEW; MIDDLE AGED; OCCULT CANCER; PLEURA METASTASIS; POSTOPERATIVE PERIOD; PREOPERATIVE EVALUATION; PRIORITY JOURNAL; RETROSPECTIVE STUDY; SEGMENTECTOMY; TUMOR INVASION; VIDEO ASSISTED THORACOSCOPIC SURGERY; WEDGE RESECTION; ADENOCARCINOMA; AGED; DIAGNOSTIC IMAGING; DIFFERENTIAL DIAGNOSIS; LUNG TUMOR; PATHOLOGY; POSITRON EMISSION TOMOGRAPHY-COMPUTED TOMOGRAPHY; PROGNOSIS;

ADENOCARCINOMA; AGED; DIAGNOSIS, DIFFERENTIAL; FEMALE; HUMANS; LUNG NEOPLASMS; LYMPHATIC METASTASIS; MALE; MIDDLE AGED; NEOPLASM INVASIVENESS; NEOPLASM STAGING; POSITRON EMISSION TOMOGRAPHY COMPUTED TOMOGRAPHY; PROGNOSIS; RETROSPECTIVE STUDIES;

EID: 85027923756     PISSN: 00034975     EISSN: 15526259     Source Type: Journal    
DOI: 10.1016/j.athoracsur.2015.11.056     Document Type: Article

References (30)

1. Parkin, D.M., Ferlay, J., Curado, M.P., et al. Fifty years of cancer incidence: CI5 I-IX. Int J Cancer 127 (2010), 2918–2927.
2. Aberle, D.R., Adams, A.M., Berg, C.D., et al. Reduced lung-cancer mortality with low-dose computed tomographic screening. N Engl J Med 365 (2011), 395–409.
3. Ye, B., Cheng, M., Li, W., et al. Predictive factors for lymph node metastasis in clinical stage IA lung adenocarcinoma. Ann Thorac Surg 98 (2014), 217–223.
4. Yamazaki, K., Yoshino, I., Yohena, T., et al. Clinically predictive factors of pathologic upstaging in patients with peripherally located clinical stage IA non-small cell lung cancer. Lung Cancer 55 (2007), 365–369.
5. Haruki, T., Aokage, K., Miyoshi, T., et al. Mediastinal nodal involvement in patients with clinical stage I non-small-cell lung cancer: possibility of rational lymph node dissection. J Thorac Oncol 10 (2015), 930–936.
6. Kirmani, B.H., Rintoul, R.C., Win, T., et al. Stage migration: results of lymph node dissection in the era of modern imaging and invasive staging for lung cancer. Eur J Cardiothorac Surg 43 (2013), 104–110.
7. Vansteenkiste, J., De Ruysscher, D., Eberhardt, W.E., et al. Early and locally advanced non-small-cell lung cancer (NSCLC): ESMO clinical practice guidelines for diagnosis, treatment and follow-up. Ann Oncol 24:Suppl 6 (2013), 89–98.
8. Ginsberg, R.J., Rubinstein, L.V., Randomized trial of lobectomy versus limited resection for T1 N0 non-small cell lung cancer. Lung Cancer Study Group. Ann Thorac Surg 60 (1995), 615–623.
9. Nakamura, K., Saji, H., Nakajima, R., et al. A phase III randomized trial of lobectomy versus limited resection for small-sized peripheral non-small cell lung cancer (JCOG0802/WJOG4607L). Jpn J Clin Oncol 40 (2010), 271–274.
10. Eguchi, T., Kadota, K., Park, B.J., Travis, W.D., Jones, D.R., Adusumilli, P.S., The New IASLC-ATS-ERS lung adenocarcinoma classification: what the surgeon should know. Semin Thorac Cardiovasc Surg 26 (2014), 210–222.
11. Travis, W.D., Brambilla, E., Noguchi, M., et al. International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society international multidisciplinary classification of lung adenocarcinoma. J Thorac Oncol 6 (2011), 244–285.
12. Yanagawa, N., Shiono, S., Abiko, M., Ogata, S.Y., Sato, T., Tamura, G., The correlation of the International Association for the Study of Lung Cancer (IASLC)/American Thoracic Society (ATS)/European Respiratory Society (ERS) classification with prognosis and EGFR mutation in lung adenocarcinoma. Ann Thorac Surg 98 (2014), 453–458.
13. Kadota, K., Villena-Vargas, J., Yoshizawa, A., et al. Prognostic significance of adenocarcinoma in situ, minimally invasive adenocarcinoma, and nonmucinous lepidic predominant invasive adenocarcinoma of the lung in patients with stage I disease. Am J Surg Pathol 38 (2014), 448–460.
14. Ito, M., Miyata, Y., Kushitani, K., et al. Prediction for prognosis of resected pT1a-1bN0M0 adenocarcinoma based on tumor size and histological status: relationship of TNM and IASLC/ATS/ERS classifications. Lung Cancer 85 (2014), 270–275.
15. Zhang, J., Wu, J., Tan, Q., Zhu, L., Gao, W., Why do pathological stage IA lung adenocarcinomas vary from prognosis? A clinicopathologic study of 176 patients with pathological stage IA lung adenocarcinoma based on the IASLC/ATS/ERS classification. J Thorac Oncol 8 (2013), 1196–1202.
16. Moon, Y., Kim, K.S., Sung, S.W., et al. Correlation of histological components with tumor invasion in pulmonary adenocarcinoma. World J Surg Oncol, 12, 2014, 388.
17. Edge, S.B., Byrd, D.R., Compton, C.C., Fritz, A.G., Greene, F.L., Trotti, A., AJCC cancer staging manual. 7th ed., 2010, Springer, New York.
18. Shin, S., Kim, H.K., Choi, Y.S., Kim, K., Kim, J., Shim, Y.M., Prognosis of unexpected and expected pathologic N1 non-small cell lung cancer. Ann Thorac Surg 96 (2013), 969–976.
19. Lu, P., Sun, Y., Sun, Y., Yu, L., The role of (18)F-FDG PET/CT for evaluation of metastatic mediastinal lymph nodes in patients with lung squamous-cell carcinoma or adenocarcinoma. Lung Cancer 85 (2014), 53–58.
20. Mehran, R., The role of surgery in patients with clinical N2 disease. Thorac Surg Clin 23 (2013), 327–335.
21. Chao, L., Yi-Sheng, H., Yu, C., et al. Relevance of EGFR mutation with micropapillary pattern according to the novel IASLC/ATS/ERS lung adenocarcinoma classification and correlation with prognosis in Chinese patients. Lung Cancer 86 (2014), 164–169.
22. Sumiyoshi, S., Yoshizawa, A., Sonobe, M., et al. Pulmonary adenocarcinomas with micropapillary component significantly correlate with recurrence, but can be well controlled with EGFR tyrosine kinase inhibitors in the early stages. Lung Cancer 81 (2013), 53–59.
23. Zhang, Y., Wang, R., Cai, D., et al. A comprehensive investigation of molecular features and prognosis of lung adenocarcinoma with micropapillary component. J Thorac Oncol 9 (2014), 1772–1778.
24. Nitadori, J., Bograd, A.J., Kadota, K., et al. Impact of micropapillary histologic subtype in selecting limited resection versus lobectomy for lung adenocarcinoma of 2 cm or smaller. J Natl Cancer Inst 105 (2013), 1212–1220.
25. Yeh, Y.C., Wu, Y.C., Chen, C.Y., Wang, L.S., Hsu, W.H., Chou, T.Y., Stromal invasion and micropapillary pattern in 212 consecutive surgically resected stage I lung adenocarcinomas: histopathological categories for prognosis prediction. J Clin Pathol 65 (2012), 910–918.
26. Zhang, J., Liang, Z., Gao, J., Luo, Y., Liu, T., Pulmonary adenocarcinoma with a micropapillary pattern: a clinicopathological, immunophenotypic and molecular analysis. Histopathology 59 (2011), 1204–1214.
27. Hung, J.J., Yeh, Y.C., Jeng, W.J., et al. Predictive value of the International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society classification of lung adenocarcinoma in tumor recurrence and patient survival. J Clin Oncol 32 (2014), 2357–2364.
28. Sica, G., Yoshizawa, A., Sima, C.S., et al. A grading system of lung adenocarcinomas based on histologic pattern is predictive of disease recurrence in stage I tumors. Am J Surg Pathol 34 (2010), 1155–1162.
29. Hattori, A., Suzuki, K., Matsunaga, T., et al. Is limited resection appropriate for radiologically “solid” tumors in small lung cancers?. Ann Thorac Surg 94 (2012), 212–215.
30. Li, M., Wu, N., Zheng, R., et al. Primary tumor PET/CT [(1)(8)F]FDG uptake is an independent predictive factor for regional lymph node metastasis in patients with non-small cell lung cancer. Cancer Imaging 12 (2013), 566–572.