Preparation and characterization of PEG-coated silica nanoparticles for oral insulin delivery

International journal of pharmaceutics

Volumn 473, Issue 1-2, 2014, Pages 627-635

  Andreani, Tatiana ^a   de Souza, Ana L uiza R ^a   Kiill, Charlene P ^a   Lorenzón, Esteban N ^a   Fangueiro, Joana F ^a   Calpena, Ana C ristina ^a   Chaud, Marco V ^a   Garcia, Maria L ^a   Gremião, Maria P almira D ^a   Silva, Amélia M ^a   Souto, Eliana B ^a  

^a UNIVERSIDADE FERNANDO PESSOA   (Portugal)

Author keywords

HPLC validation; Insulin; Mathematic modeling; Oral delivery; PEG adsorption; Silica nanoparticles

Indexed keywords

DRUG CARRIER; HUMAN INSULIN; MACROGOL DERIVATIVE; NANOPARTICLE; SILICON DIOXIDE;

ANIMAL; CHEMISTRY; CIRCULAR DICHROISM; DRUG FORMULATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VITRO STUDY; INTESTINE ABSORPTION; MALE; METABOLISM; ORAL DRUG ADMINISTRATION; SMALL INTESTINE; WISTAR RAT;

ADMINISTRATION, ORAL; ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CIRCULAR DICHROISM; DRUG CARRIERS; DRUG COMPOUNDING; IN VITRO TECHNIQUES; INSULIN, REGULAR, HUMAN; INTESTINAL ABSORPTION; INTESTINE, SMALL; MALE; NANOPARTICLES; POLYETHYLENE GLYCOLS; RATS, WISTAR; SILICON DIOXIDE;

EID: 85027923100     PISSN: None     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2014.07.049     Document Type: Article

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