Mixed state and suicide: Is the effect of mixed state on suicidal behavior more than the sum of its parts?

Bipolar Disorders

Volumn 20, Issue 1, 2018, Pages 35-41

  Persons, Jane E ^a,b   Coryell, William H ^b   Solomon, David A ^c,d   Keller, Martin B ^c   Endicott, Jean ^e   Fiedorowicz, Jess G ^a,b  

^a UNIVERSITY OF IOWA   (United States)

^b UNIVERSITY OF IOWA   (United States)

^c BROWN UNIVERSITY   (United States)

^d UpToDate   (United States)

^e New York Presbyterian Columbia University Medical Center   (United States)

Author keywords

bipolar; bipolar mixed; depression; mania; suicide

Indexed keywords

ADULT; ARTICLE; BIPOLAR DISORDER; COMORBIDITY; CONTROLLED STUDY; FEMALE; FRAILTY; HIGH RISK PATIENT; HUMAN; HYPOMANIA; MAJOR CLINICAL STUDY; MALE; MEDICAL HISTORY; NEUROSIS; PREDICTOR VARIABLE; PREVALENCE; PRIORITY JOURNAL; SUBSTANCE USE; SUICIDE; SUICIDE ATTEMPT; COMPLICATION; DEPRESSION; EMOTIONAL DISORDER; MIDDLE AGED; PSYCHOLOGICAL RATING SCALE; PSYCHOLOGY; RISK ASSESSMENT; SEVERITY OF ILLNESS INDEX; SUICIDAL IDEATION;

ADULT; AFFECTIVE SYMPTOMS; BIPOLAR DISORDER; DEPRESSION; FEMALE; HUMANS; MALE; MIDDLE AGED; PSYCHIATRIC STATUS RATING SCALES; RISK ASSESSMENT; SEVERITY OF ILLNESS INDEX; SUICIDAL IDEATION; SUICIDE;

EID: 85027878422     PISSN: 13985647     EISSN: 13995618     Source Type: Journal    
DOI: 10.1111/bdi.12538     Document Type: Article

References (33)

1. Rihmer A, Gonda X, Balazs J, et al. The importance of depressive mixed states in suicidal behaviour. Neuropsychopharmacol Hung. 2008;10:45-49.
2. Swann AC, Lafer B, Perugi G, et al. Bipolar mixed states: an international society for bipolar disorders task force report of symptom structure, course of illness, and diagnosis. Am J Psychiatry. 2013;170:31-42.
3. Shim IH, Woo YS, Bahk WM. Prevalence rates and clinical implications of bipolar disorder “with mixed features” as defined by DSM-5. J Affect Disord. 2015;173:120-125.
4. Pompili M, Gonda X, Serafini G, et al. Epidemiology of suicide in bipolar disorders: a systematic review of the literature. Bipolar Disord. 2013;15:457-490.
5. Swann AC, Steinberg JL, Lijffijt M, et al. Continuum of depressive and manic mixed states in patients with bipolar disorder: quantitative measurement and clinical features. World Psychiatry. 2009;8:166-172.
6. Cassidy F, Murry E, Forest K, et al. Signs and symptoms of mania in pure and mixed episodes. J Affect Disord. 1998;50:187-201.
7. Goldberg JF, Perlis RH, Bowden CL, et al. Manic symptoms during depressive episodes in 1380 patients with bipolar disorder: findings from the STEP-BD. Am J Psychiatry. 2009;166:173-181.
8. Pacchiarotti I, Mazzarini L, Kotzalidis GD, et al. Mania and depression. Mixed, not stirred. J Affect Disord. 2011;133:105-113.
9. Strakowski SM, McElroy SL, Keck PE Jr, et al. Suicidality among patients with mixed and manic bipolar disorder. Am J Psychiatry. 1996;153:674-676.
10. Balazs J, Benazzi F, Rihmer Z, et al. The close link between suicide attempts and mixed (bipolar) depression: implications for suicide prevention. J Affect Disord. 2006;91:133-138.
11. Gonzalez-Pinto A, Barbeito S, Alonso M, et al. Poor long-term prognosis in mixed bipolar patients: 10-year outcomes in the Vitoria prospective naturalistic study in Spain. J Clin Psychiatry. 2011;72:671-676.
12. Johnson SL, McMurrich SL, Yates M. Suicidality in bipolar I disorder. Suicide Life Threat Behav. 2005;35:681-689.
13. Fiedorowicz JG, Solomon DA, Endicott J, et al. Manic/hypomanic symptom burden and cardiovascular mortality in bipolar disorder. Psychosom Med. 2009;71:598-606.
14. Akhter A, Fiedorowicz JG, Zhang T, et al. Seasonal variation of manic and depressive symptoms in bipolar disorder. Bipolar Disord. 2013;15:377-384.
15. Fiedorowicz JG, Coryell WH, Rice JP, et al. Vasculopathy related to manic/hypomanic symptom burden and first-generation antipsychotics in a sub-sample from the collaborative depression study. Psychother Psychosom. 2012;81:235-243.
16. Fiedorowicz JG, Leon AC, Keller MB, et al. Do risk factors for suicidal behavior differ by affective disorder polarity? Psychol Med. 2009;39:763-771.
17. Fiedorowicz JG, Endicott J, Solomon DA, et al. Course of illness following prospectively observed mania or hypomania in individuals presenting with unipolar depression. Bipolar Disord. 2012;14:664-671.
18. Fiedorowicz JG, Endicott J, Leon AC, et al. Subthreshold hypomanic symptoms in progression from unipolar major depression to bipolar disorder. Am J Psychiatry. 2011;168:40-48.
19. Fiedorowicz JG, Palagummi NM, Behrendtsen O, et al. Cholesterol and affective morbidity. Psychiatry Res. 2010;175:78-81.
20. Fiedorowicz JG, Coryell WH. Cholesterol and suicide attempts: a prospective study of depressed inpatients. Psychiatry Res. 2007;152:11-20.
21. Leon AC, Fiedorowicz JG, Solomon DA, et al. Risk of suicidal behavior with antidepressants in bipolar and unipolar disorders. J Clin Psychiatry. 2014;75:720-727.
22. Leon AC, Solomon DA, Li C, et al. Antidepressants and risks of suicide and suicide attempts: a 27-year observational study. J Clin Psychiatry. 2011;72:580-586.
23. Leon AC, Solomon DA, Li C, et al. Antiepileptic drugs for bipolar disorder and the risk of suicidal behavior: a 30-year observational study. Am J Psychiatry. 2012;169:285-291.
24. Endicott J, Spitzer RL. A diagnostic interview: the schedule for affective disorders and schizophrenia. Arch Gen Psychiatry. 1978;35:837-844.
25. Endicott J, Spitzer RL. Use of the research diagnostic criteria and the schedule for affective disorders and schizophrenia to study affective disorders. Am J Psychiatry. 1979;136:52-56.
26. Holma KM, Melartin TK, Haukka J, et al. Incidence and predictors of suicide attempts in DSM-IV major depressive disorder: a five-year prospective study. Am J Psychiatry. 2010;167:801-808.
27. Amorim LD, Cai J. Modelling recurrent events: a tutorial for analysis in epidemiology. Int J Epidemiol. 2015;44:324-333.
28. Sala R, Goldstein BI, Morcillo C, et al. Course of comorbid anxiety disorders among adults with bipolar disorder in the U.S. population. J Psychiatr Res. 2012;46:865-872.
29. Goes FS. The importance of anxiety states in bipolar disorder. Curr Psychiatry Rep. 2015;17:3.
30. Schaffer A, Isometsa ET, Tondo L, et al. International society for bipolar disorders task force on suicide: meta-analyses and meta-regression of correlates of suicide attempts and suicide deaths in bipolar disorder. Bipolar Disord. 2015;17:1-16.
31. Swann AC, Moeller FG, Steinberg JL, et al. Manic symptoms and impulsivity during bipolar depressive episodes. Bipolar Disord. 2007;9:206-212.
32. Solomon DA, Fiedorowicz JG, Leon AC, et al. Recovery from multiple episodes of bipolar I depression. J Clin Psychiatry. 2013;74:e205-e211.
33. Perlis RH, Dennehy EB, Miklowitz DJ, et al. Retrospective age at onset of bipolar disorder and outcome during two-year follow-up: results from the STEP-BD study. Bipolar Disord. 2009;11:391-400.