The Pathogenic Role of NLRP3 Inflammasome Activation in Inflammatory Bowel Diseases of Both Mice and Humans

Journal of Crohn's & colitis

Volumn 11, Issue 6, 2017, Pages 737-750

  Liu, Ling ^a   Dong, Ying ^a   Ye, Mei ^a   Jin, Shi ^a   Yang, Jianbo ^a   Joosse, Maria E ^a   Sun, Yu ^a   Zhang, Jennifer ^a   Lazarev, Mark ^a   Brant, Steven R ^a   Safar, Bashar ^a   Marohn, Michael ^a   Mezey, Esteban ^a   Li, Xuhang ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

IL 10; inflammatory bowel diseases IBD ; NLRP3 inflammasome

Indexed keywords

ANTIDIABETIC AGENT; ANTIINFECTIVE AGENT; APOPTOSIS REGULATORY PROTEIN; CASPASE RECRUITMENT DOMAIN SIGNALING PROTEIN; CELL SURFACE RECEPTOR; CRYOPYRIN; CYTOKINE; GLIBENCLAMIDE; IL10 PROTEIN, MOUSE; INFLAMMASOME; INTERLEUKIN 10; INTERLEUKIN 1BETA CONVERTING ENZYME; LIPOPOLYSACCHARIDE; NALP1 PROTEIN, MOUSE; NIGERICIN; NLRP3 PROTEIN, HUMAN; NLRP3 PROTEIN, MOUSE; NOD-LIKE RECEPTOR PYRIN DOMAIN-CONTAINING PROTEIN 6, MOUSE; PYCARD PROTEIN, MOUSE; SIGNAL TRANSDUCING ADAPTOR PROTEIN;

ANIMAL; COLON; CROHN DISEASE; DRUG EFFECTS; EPITHELIUM CELL; GENETICS; HUMAN; INTESTINE MUCOSA; KNOCKOUT MOUSE; MACROPHAGE; METABOLISM; MICROSCOPIC COLITIS; MOUSE; PATHOLOGY; TISSUE CULTURE TECHNIQUE; UPREGULATION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; ANTI-BACTERIAL AGENTS; APOPTOSIS REGULATORY PROTEINS; CARD SIGNALING ADAPTOR PROTEINS; CASPASE 1; COLITIS, MICROSCOPIC; COLON; CROHN DISEASE; CYTOKINES; EPITHELIAL CELLS; GLYBURIDE; HUMANS; HYPOGLYCEMIC AGENTS; INFLAMMASOMES; INTERLEUKIN-10; INTESTINAL MUCOSA; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; MICE, KNOCKOUT; NIGERICIN; NLR FAMILY, PYRIN DOMAIN-CONTAINING 3 PROTEIN; RECEPTORS, CELL SURFACE; TISSUE CULTURE TECHNIQUES; UP-REGULATION;

EID: 85027693631     PISSN: None     EISSN: 18764479     Source Type: Journal    
DOI: 10.1093/ecco-jcc/jjw219     Document Type: Article

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