Electrospun Nanofibers: New Concepts, Materials, and Applications

Accounts of Chemical Research

Volumn 50, Issue 8, 2017, Pages 1976-1987

  Xue, Jiajia ^a   Xie, Jingwei ^b   Liu, Wenying ^c   Xia, Younan ^a,c  

^a GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

^b UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^c Georgia Institute of Technology   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NANOFIBER;

DRUG DELIVERY SYSTEM; ELECTROCHEMICAL ANALYSIS; PROCEDURES; TISSUE ENGINEERING;

DRUG DELIVERY SYSTEMS; ELECTROCHEMICAL TECHNIQUES; NANOFIBERS; TISSUE ENGINEERING;

EID: 85027436101     PISSN: 00014842     EISSN: 15204898     Source Type: Journal    
DOI: 10.1021/acs.accounts.7b00218     Document Type: Article

References (61)

1. Boys, C. V. On the Production, Properties, and Some Suggested Uses of the Finest Threads Proc. Phys. Soc. London 1887, 9, 8-19 10.1088/1478-7814/9/1/303
2. Cooley, J. F. Apparatus for Electrically Dispersing Fluids. U.S. Patent 692,631, 1902.
3. Morton, W. J. Method of Dispersing Fluid. U.S. Patent 705,691, 1902.
4. Formhals, A.; Gastell, S. R. Process and Apparatus for Preparing Artificial Threads. U.S. Patent 1,975,504, 1934.
5. Formhals, A. Method and Apparatus for Spinning. U.S. Patent 2,349,950, 1944.
6. Taylor, G. Disintegration of Water Droplets in an Electric Field Proc. R. Soc. London, Ser. A 1964, 280, 383-397 10.1098/rspa.1964.0151
7. Taylor, G. The Force Exerted by an Electric Field on a Long Cylindrical Conductor Proc. R. Soc. London, Ser. A 1966, 291, 145-158 10.1098/rspa.1966.0085
8. Taylor, G. Electrically Driven Jets Proc. R. Soc. London, Ser. A 1969, 313, 453-475 10.1098/rspa.1969.0205
9. Doshi, J.; Reneker, D. H. Electrospinning Process and Applications of Electropsun Fibers. Proceedings of IEEE Industry Application Society 28th Annual Meeting, Toronto, Canada, October 2-8, 1993.
10. Yarin, A. L.; Koombhongse, S.; Reneker, D. H. Bending Instability in Electrospinning of Nanofibers J. Appl. Phys. 2001, 89, 3018-3026 10.1063/1.1333035
11. Reneker, D. H.; Yarin, A. L. Electrospinning Jets and Polymer Nanofibers Polymer 2008, 49, 2387-2425 10.1016/j.polymer.2008.02.002
12. Kowalewski, T. A.; Blonski, S.; Barral, S. Experiments and Modeling of Electrospinning Process Bull. Pol. Acad. Sci.: Tech. Sci. 2005, 53, 385-394
13. Burger, C.; Hsiao, B. S.; Chu, B. Nanofibrous Materials and Their Applications Annu. Rev. Mater. Res. 2006, 36, 333-368 10.1146/annurev.matsci.36.011205.123537
14. Li, D.; McCann, J. T.; Xia, Y.; Marquez, M. Electrospinning: A Simple and Versatile Technique for Producing Ceramic Nanofibers and Nanotubes J. Am. Ceram. Soc. 2006, 89, 1861-1869 10.1111/j.1551-2916.2006.00989.x
15. Li, D.; Xia, Y. Fabrication of Titania Nanofibers by Electrospinning Nano Lett. 2003, 3, 555-560 10.1021/nl034039o
16. Li, D.; Herricks, T.; Xia, Y. Magnetic Nanofibers of Nickel Ferrite Prepared by Electrospinning Appl. Phys. Lett. 2003, 83, 4586-4588 10.1063/1.1630844
17. McCann, J. T.; Chen, J. I. L.; Li, D.; Ye, Z.; Xia, Y. Electrospinning of Polycrystalline Barium Titanate Nanofibers with Controllable Morphology and Alignment Chem. Phys. Lett. 2006, 424, 162-166 10.1016/j.cplett.2006.04.082
18. Formo, E.; Yavuz, M. S.; Lee, E. P.; Lane, L.; Xia, Y. Functionalization of Electrospun Ceramic Nanofiber Membranes with Noble-Metal Nanostructures for Catalytic Applications J. Mater. Chem. 2009, 19, 3878-3882 10.1039/b901509d
19. 2 Nanofibers for the Water-Gas Shift Reaction Adv. Funct. Mater. 2015, 25, 4153-4162 10.1002/adfm.201501392
20. Li, D.; McCann, J. T.; Xia, Y. Use of Electrospinning to Directly Fabricate Hollow Nanofibers with Functionalized Inner and Outer Surfaces Small 2005, 1, 83-86 10.1002/smll.200400056
21. McCann, J. T.; Li, D.; Xia, Y. Electrospinning of Nanofibers with Core-Sheath, Hollow, or Porous Structures J. Mater. Chem. 2005, 15, 735-738 10.1039/b415094e
22. Xie, J.; Li, X.; Xia, Y. Put Electrospun Nanofibers to Work for Biomedical Research Macromol. Rapid Commun. 2008, 29, 1775-1792 10.1002/marc.200800381
23. Lu, P.; Xia, Y. Maneuvering the Internal Porosity and Surface Morphology of Electrospun Polystyrene Yarns by Controlling the Solvent and Relative Humidity Langmuir 2013, 29, 7070-7078 10.1021/la400747y
24. McCann, J. T.; Marquez, M.; Xia, Y. Highly Porous Fibers by Electrospinning into a Cryogenic Liquid J. Am. Chem. Soc. 2006, 128, 1436-1437 10.1021/ja056810y
25. Bognitzki, M.; Frese, T.; Steinhart, M.; Greiner, A.; Schaper, A.; Wendorff, J. H.; Hellwig, M. Preparation of Fibers with Nanoscaled Morphologies: Electrospinning of Polymer Blends Polym. Eng. Sci. 2001, 41, 982-989 10.1002/pen.10799
26. Li, D.; Xia, Y. Direction Fabrication of Composite and Ceramic Hollow Nanofibers by Electrospinning Nano Lett. 2004, 4, 933-938 10.1021/nl049590f
27. Chen, H.; Wang, N.; Di, J.; Zhao, Y.; Song, Y.; Jiang, L. Nanowire-in-Microtube Structured Core/Shell Fibers via Multifluidic Co-Axial Electrospinning Langmuir 2010, 26, 11291-11296 10.1021/la100611f
28. Teo, W. E.; Ramakrishna, S. A Review on Electrospinning Design and Nanofibre Assemblies Nanotechnology 2006, 17, R89-R106 10.1088/0957-4484/17/14/R01
29. Li, D.; Wang, Y.; Xia, Y. Electrospinning of Polymeric and Ceramic Nanofibers as Uniaxially Aligned Arrays Nano Lett. 2003, 3, 1167-1171 10.1021/nl0344256
30. Li, D.; Ouyang, G.; McCann, J. T.; Xia, Y. Collecting Electrospun Nanofibers with Patterned Electrodes Nano Lett. 2005, 5, 913-916 10.1021/nl0504235
31. Yang, D.; Lu, B.; Zhao, Y.; Jiang, X. Fabrication of Aligned Fibrous Arrays by Magnetic Electrospinning Adv. Mater. 2007, 19, 3702-3706 10.1002/adma.200700171
32. Li, D.; Wang, Y.; Xia, Y. Electrospinning Nanofibers as Uniaxially Aligned Arrays and Layer-by-Layer Stacked Films Adv. Mater. 2004, 16, 361-366 10.1002/adma.200306226
33. 2 Nanofibers: A New Class of Hierarchical Nanostructures Enabled by Electrospinning and Calcination Nano Lett. 2006, 6, 1297-1302 10.1021/nl060928a
34. 2 Nanofibers with Pt Nanostructures: the Effect of Surface Roughness on Nucleation Mechanism and Morphology Control Chem. Phys. Lett. 2009, 476, 56-61 10.1016/j.cplett.2009.05.075
35. Formo, E.; Peng, Z.; Lee, E.; Lu, X.; Yang, H.; Xia, Y. Direct Oxidation of Methanol on Pt Nanostructures Supported on Electrospun Nanofibers of Anatase J. Phys. Chem. C 2008, 112, 9970-9975 10.1021/jp803763q
36. 2 Nanofibers with Pt Nanoparticles and Nanowires for Catalytic Applications Nano Lett. 2008, 8, 668-672 10.1021/nl073163v
37. Dai, Y.; Lu, X.; McKiernan, M.; Lee, E. P.; Sun, Y.; Xia, Y. Hierarchical Nanostructures of K-birnessite Nanoplates on Anatase Nanofibers and Their Application for Decoloration of Dye Solution J. Mater. Chem. 2010, 20, 3157-3162 10.1039/c000446d
38. Lu, P.; Xia, Y. Novel Nanostructures of Rutile Fabricated by Templating against Yarns of Polystyrene Nanofibrils and Their Catalytic Applications ACS Appl. Mater. Interfaces 2013, 5, 6391-6399 10.1021/am4015633
39. 2 Nanofibers and Covered by Porous Silica Angew. Chem., Int. Ed. 2010, 49, 8165-8168 10.1002/anie.201001839
40. 2 Hollow Fibers Angew. Chem., Int. Ed. 2012, 51, 9543-9546 10.1002/anie.201203755
41. Liu, W.; Thomopoulos, S.; Xia, Y. Electrospun Nanofibers for Regenerative Medicine Adv. Healthcare Mater. 2012, 1, 10-25 10.1002/adhm.201100021
42. Sharma, P.; Maffulli, N. Biology of Tendon Injury: Healing, Modeling and Remodeling J. Musculoskeletal Neuronal Interact. 2006, 6, 181-190
43. Xie, J.; Li, X.; Lipner, J.; Manning, C. N.; Schwartz, A. G.; Thomopoulos, S.; Xia, Y. Aligned-to-Random" Nanofiber Scaffolds for Mimicking the Structure of the Tendon-to-Bone Insertion Site Nanoscale 2010, 2, 923-926 10.1039/c0nr00192a
44. Liu, W.; Lipner, J.; Moran, C. H.; Feng, L.; Li, X.; Thomopoulos, S.; Xia, Y. Generation of Electrospun Nanofibers with Controllable Degrees of Crimping Through a Simple, Plasticizer-Based Treatment Adv. Mater. 2015, 27, 2583-2588 10.1002/adma.201500329
45. Xie, J.; MacEwan, M. R.; Liu, W.; Jesuraj, N.; Li, X.; Hunter, D.; Xia, Y. Nerve Guidance Conduits Based on Double-Layered Scaffolds of Electrospun Nanofibers for Repairing the Peripheral Nervous System ACS Appl. Mater. Interfaces 2014, 6, 9472-9480 10.1021/am5018557
46. Han, J.; Wu, Q.; Xia, Y.; Wagner, M. B.; Xu, C. Cell Alignment Induced by Anisotropic Electrospun Fibrous Scaffolds Alone has Limited Effect on Cardiomyocyte Maturation Stem Cell Res. 2016, 16, 740-750 10.1016/j.scr.2016.04.014
47. Xie, J.; MacEwan, M. R.; Ray, W. Z.; Liu, W.; Siewe, D. Y.; Xia, Y. Radially Aligned, Electrospun Nanofibers as Dural Substitutes for Wound Closure and Tissue Regeneration Applications ACS Nano 2010, 4, 5027-5036 10.1021/nn101554u
48. Xie, J.; MacEwan, M. R.; Schwartz, A. G.; Xia, Y. Electrospun Nanofibers for Neural Tissue Engineering Nanoscale 2010, 2, 35-44 10.1039/B9NR00243J
49. Xie, J.; MacEwan, M. R.; Li, X.; Sakiyama-Elbert, S. E.; Xia, Y. Neurite Outgrowth on Nanofiber Scaffolds with Different Orders, Structures, and Surface Properties ACS Nano 2009, 3, 1151-1159 10.1021/nn900070z
50. Xie, J.; Willerth, S. M.; Li, X.; MacEwan, M. R.; Rader, A.; Sakiyama-Elbert, S. E.; Xia, Y. The Differentiation of Embryonic Stem Cells Seeded on Electrospun Nanofibers into Neural Lineages Biomaterials 2009, 30, 354-362 10.1016/j.biomaterials.2008.09.046
51. Xie, J.; MacEwan, M. R.; Willerth, S. M.; Li, X.; Moran, D. W.; Sakiyama-Elbert, S. E.; Xia, Y. Conductive Core-Sheath Nanofibers and Their Potential Applications in Neural Tissue Engineering Adv. Funct. Mater. 2009, 19, 2312-2318 10.1002/adfm.200801904
52. Xie, J.; Liu, W.; MacEwan, M. R.; Yeh, Y. Y.; Thomopoulos, S.; Xia, Y. Nanofiber Membranes with Controllable Microwells and Structural Cues and Their Use in Forming Cell Microarrays and Neuronal Networks Small 2011, 7, 293-297 10.1002/smll.201001446
53. Schnell, E.; Klinkhammer, K.; Balzer, S.; Brook, G.; Klee, D.; Dalton, P.; Mey, J. Guidance of Glia Cell Migration and Axonal Growth on Electrospun Nanofibers of Poly-ε-Caprolactone and a Collagen/Poly-ε-Caprolactone Blend Biomaterials 2007, 28, 3012-3025 10.1016/j.biomaterials.2007.03.009
54. Corey, J. M.; Lin, D. Y.; Mycek, K. B.; Chen, Q.; Samuel, S.; Feldman, E. L.; Martin, D. C. Aligned Electrospun Nanofibers Specify the Direction of Dorsal Root Ganglia Neurite Growth J. Biomed. Mater. Res., Part A 2007, 83A, 636-645 10.1002/jbm.a.31285
55. Wang, H.; Mullins, M. E.; Cregg, J. M.; Hurtado, A.; Oudega, M.; Trombley, M. T.; Gilbert, R. J. Creation of Highly Aligned Electrospun Poly-L-Lactic Acid Fibers for Nerve Regeneration Applications J. Neural Eng. 2009, 6, 016001 10.1088/1741-2560/6/1/016001
56. Xie, J.; Liu, W.; MacEwan, M. R.; Bridgman, P. C.; Xia, Y. Neurite Outgrowth on Electrospun Nanofibers with Uniaxial Alignment: The Effects of Fiber Density, Surface Coating, and Supporting Substrate ACS Nano 2014, 8, 1878-1885 10.1021/nn406363j
57. Xue, J.; Yang, J.; O'Connor, D. M.; Zhu, C.; Huo, D.; Boulis, N. M.; Xia, Y. Differentiation of Bone Marrow Stem Cells into Schwann Cells for the Promotion of Neurite Outgrowth on Electrospun Fibers ACS Appl. Mater. Interfaces 2017, 9, 12299-12310 10.1021/acsami.7b00882
58. Li, X.; Xie, J.; Lipner, J.; Yuan, Y.; Thomopoulos, S.; Xia, Y. Nanofiber Scaffolds with Gradations in Mineral Content for Mimicking the Tendon-to-Bone Insertion Site Nano Lett. 2009, 9, 2763-2768 10.1021/nl901582f
59. Lipner, J.; Liu, W.; Liu, Y.; Boyle, J.; Genin, G. M.; Xia, Y.; Thomopoulos, S. The Mechanics of PLGA Nanofiber Scaffolds with Biomimetic Gradients in Mineral for Tendon-to-Bone Repair J. Mech. Behav. Biomed. Mater. 2014, 40, 59-68 10.1016/j.jmbbm.2014.08.002
60. Liu, W.; Lipner, J.; Xie, J.; Manning, C. N.; Thomopoulos, S.; Xia, Y. Nanofiber Scaffolds with Gradients in Mineral Content for Spatial Control of Osteogenesis ACS Appl. Mater. Interfaces 2014, 6, 2842-2849 10.1021/am405418g
61. Liu, W.; Yeh, Y. C.; Lipner, J.; Xie, J.; Sung, H. W.; Thomopoulos, S.; Xia, Y. Enhancing the Stiffness of Electrospun Nanofiber Scaffolds with a Controlled Surface Coating and Mineralization Langmuir 2011, 27, 9088-9093 10.1021/la2018105