Integron-Mediated Antibiotic Resistance in Acinetobacter baumannii Isolated from Intensive Care Unit Patients, Babol, North of Iran

BioMed Research International

Volumn 2017, Issue , 2017, Pages

  Deylam Salehi, Mitra ^a   Ferdosi Shahandashti, Elaheh ^b   Yahyapour, Yosef ^a   Khafri, Soraya ^a   Pournajaf, Abazar ^c   Rajabnia, Ramazan ^a  

^a BABOL UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c IRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

[No Author keywords available]

Indexed keywords

AMIKACIN; CEFTAZIDIME; CIPROFLOXACIN; CLASS I INTEGRASE; CLASS II INTEGRASE; CLASS III INTEGRASE; COLISTIN; GENTAMICIN; IMIPENEM; INTEGRASE; MEROPENEM; PIPERACILLIN PLUS TAZOBACTAM; POLYMYXIN; TIGECYCLINE; UNCLASSIFIED DRUG;

ACINETOBACTER BAUMANNII; ACUTE ABDOMEN; ADOLESCENT; ADULT; AGED; ANTIBIOTIC RESISTANCE; APACHE; ARTICLE; BACTERIUM ISOLATE; BACTERIUM ISOLATION; COLONY FORMING UNIT; CROSS-SECTIONAL STUDY; DIABETES MELLITUS; DISK DIFFUSION; EXTENSIVELY DRUG RESISTANCE; FEMALE; HEMATOLOGIC DISEASE; HUMAN; INJURY; INTEGRON; INTENSIVE CARE; IRAN; KIDNEY FAILURE; LENGTH OF STAY; LUNG LAVAGE; MAJOR CLINICAL STUDY; MALE; MALIGNANT NEOPLASM; MULTIDRUG RESISTANCE; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; RESPIRATORY FAILURE; GENETICS; INTENSIVE CARE UNIT; ISOLATION AND PURIFICATION;

ACINETOBACTER BAUMANNII; CEFTAZIDIME; DISK DIFFUSION ANTIMICROBIAL TESTS; DRUG RESISTANCE, BACTERIAL; FEMALE; HUMANS; INTEGRONS; INTENSIVE CARE UNITS; IRAN; MALE;

EID: 85027152632     PISSN: 23146133     EISSN: 23146141     Source Type: Journal    
DOI: 10.1155/2017/7157923     Document Type: Article

References (32)

1. P. K. Sahu, P. S. Iyer, S. H. Barage, K. D. Sonawane, and B. A. Chopade, "Characterization of the algC gene expression pattern in the multidrug resistant Acinetobacter baumannii AIIMS 7 and correlation with biofilm development on abiotic surface, " ScientificWorld Journal, vol. 2014, Article ID 593546, 2014.
2. D. E. Karageorgopoulos and M. E. Falagas, "Current control and treatment of multidrug-resistant Acinetobacter baumannii infections, " The Lancet Infectious Diseases, vol. 8, no. 12, pp. 751-762, 2008.
3. V. Manchanda, S. Sanchaita, and N. P. Singh, "Multidrug resistant acinetobacter, " Journal of Global Infectious Diseases, vol. 2, no. 3, pp. 291-304, 2010.
4. R. A. Bonomo and D. Szabo, "Mechanisms of multidrug resistance in Acinetobacter species and Pseudomonas aeruginosa, " Clinical Infectious Diseases, vol. 43, supplement 2, pp. S49-S56, 2006.
5. A. Z. Bialvaei, H. S. Kafil, M. Asgharzadeh, M. Aghazadeh, and M. Yousefi, "CTX-M extended-spectrum β-lactamaseproducing Klebsiella spp, Salmonella spp, Shigella spp and Escherichia coli isolates in Iranian hospitals, " Brazilian Journal of Microbiology, vol. 47, no. 3, pp. 706-711, 2016.
6. M. Taherikalani, A. Maleki, N. Sadeghifard et al., "Dissemination of class 1, 2 and 3 integrons among different multidrug resistant isolates of Acinetobacter baumannii in Tehran hospitals, Iran, " Polish Journal ofMicrobiology, vol. 60, no. 2, pp. 169-174, 2011.
7. Y. Zhu, Y. Yi, F. Liu et al., "Distribution and molecular profiling of class 1 integrons in MDR Acinetobacter baumannii isolates andwhole genome-based analysis of antibiotic resistancemechanisms in a representative strain, " Microbiological Research, vol. 169, no. 11, pp. 811-816, 2014.
8. F. MoradianKouchaksaraei, E. Ferdosi Shahandashti, Z. Molana et al., "Molecular detection of integron genes and pattern of antibiotic resistance in pseudomonas aeruginosa strains isolated from intensive care unit, Shahid Beheshti hospital, North of Iran, " International Journal of Molecular and Cellular Medicine, vol. 1, no. 4, pp. 209-217, 2012.
9. F. Ahangarkani, R. Rajabnia, E. Shahandashti, M. Bagheri, and M. Ramez, "Frequency of class 1 integron in Escherichia coli strains isolated from patients with urinary tract infections in North of Iran, " Mater Sociomed, vol. 27, no. 1, pp. 10-12, 2015.
10. C. Goldstein, M. D. Lee, S. Sanchez et al., "Incidence of class 1 and 2 integrases in clinical and commensal bacteria from livestock, companion animals, and exotics, " Antimicrobial Agents and Chemotherapy, vol. 45, no. 3, pp. 723-726, 2001.
11. M. Deylam Salehi, E. Ferdosi-Shahandashti, Y. Yahyapour, S. Khafri, A. Pournajaf, and R. Rajabnia, Molecular study ofintegrons class I, II, III and its relation to antibiotic resistance inAcintobacter strains isolated from patients in intensive care hospital Rohani Babol. [Athesis forMSc dissertation], BabolUniversity of medical sciences, Babol, Iran, 2016.
12. J. C. P. Gomes, W. L. Pedreira, E. M. P. A. Aráujo et al., "Impact of BAL in the management of pneumonia with treatment failure: positivity of BAL culture under antibiotic therapy, " Clinical Investigations in Critical Care, vol. 118, no. 6, pp. 1739-1746, 2000.
13. C. R. Zaccard, R. F. Schell, and C. A. Spiegel, "Efficacy of bilateral bronchoalveolar lavage for diagnosis of ventilator-associated pneumonia, " Journal of Clinical Microbiology, vol. 47, no. 9, pp. 2918-2924, 2009.
14. B. Vakili, H. Fazeli, P. Shoaei et al., "Detection of colistin sensitivity in clinical isolates of Acinetobacter baumannii in Iran, " Journal of Research in Medical Sciences, vol. 19, pp. S67-S70, 2014.
15. P. G. Higgins, H. Wisplinghoff, O. Krut, and H. Seifert, "APCRbasedmethod to differentiate between Acinetobacter baumannii and Acinetobacter genomic species 13TU, " Clinical Microbiology and Infection, vol. 13, no. 12, pp. 1199-1201, 2007.
16. W. Kamolvit, P. G. Higgins, D. L. Paterson, and H. Seifert, "Multiplex PCR to detect the genes encoding naturally occurring oxacillinases in Acinetobacter spp, " Journal of Antimicrobial Chemotherapy, vol. 69, no. 4, Article ID dkt480, pp. 959-963, 2014.
17. "Performance standards for antimicrobial susceptibility testing; twenty-fifth informational supplement, " Clinical and Laboratory Standards Institute, vol. 35, no. 3, pp. 44-50, 2015.
18. F. Perez, A. M. Hujer, K. M. Hujer, B. K. Decker, P. N. Rather, and R. A. Bonomo, "Global challenge of multidrug-resistant Acinetobacter baumanni, " Antimicrobial Agents and Chemotherapy, vol. 51, no. 10, pp. 3471-3484, 2007.
19. B. Nomanpour, A. Ghodousi, A. Babaei, H. Abtahi, M. Tabrizi, and M. M. Feizabadi, "Rapid, cost-effective, sensitive and quantitative detection of Acinetobacter baumannii from pneumonia patients, " Iranian Journal of Microbiology, vol. 3, no. 4, pp. 162-169, 2011.
20. H. Ghajavand, B. N. Esfahani, S. A. Havaei, S. Moghim, and H. Fazeli, "Molecular identification of Acinetobacterbaumannii isolated from intensive care units and their antimicrobial resistance patterns, " Advanced Biomedical Research, vol. 4, no. 110, 2015.
21. M.-C. Chan, S.-K. Chiu, P.-R. Hsueh, N.-C. Wang, C.-C. Wang, and C.-T. Fang, "Risk factors for healthcare-associated extensively drug-resistant Acinetobacter baumannii infections: a case-control study, " PLoS ONE, vol. 9, no. 1, article e85973, 2014.
22. M. S. Ramírez, M. S. Stietz, E. Vilacoba et al., "Increasing frequency of class 1 and 2 integrons in multidrug-resistant clones of Acinetobacter baumannii reveals the need for continuous molecular surveillance, " International Journal of Antimicrobial Agents, vol. 37, no. 2, pp. 175-177, 2011.
23. S. Kamalbeik, H. Talaie, A. Mahdavinejad, A. Karimi, and A. Salimi, "Multidrug-resistant Acinetobacter baumannii infection in intensive care unit patients in a hospital with building construction: is there an association?" Korean Journal of Anesthesiology, vol. 66, no. 4, pp. 295-299, 2014.
24. M. S. Ramírez, A. Morales, E. Vilacoba, C. Márquez, and D. Centrón, "Class 2 integrons dissemination among multidrug resistance (MDR) clones of Acinetobacter baumannii, " Current Microbiology, vol. 64, no. 3, pp. 290-293, 2012.
25. N. Martins, R. C. Picão, S. Adams-Sapper, L. W. Riley, and B. M. Moreira, "Association of class 1 and 2 integrons withmultidrugresistant Acinetobacter baumannii international clones and Acinetobacter nosocomialis isolates, " Antimicrobial Agents and Chemotherapy, vol. 59, no. 1, pp. 698-701, 2015.
26. M. Taherikalani, A. Maleki, N. Sadeghifars, D. Mohammadzadeh, P. Asadollahi, and M. Emaneini, "Dissemination of class 1, 2 and 3 integrons among differentmultidrug resistant isolates of Acinetobacter baumannii in Tehran hospitals, Iran, " Polish Journal of Microbiology, vol. 60, no. 2, pp. 169-174, 2011.
27. F. Moammadi, M. Arabestani, M. Safari, G. Roshanaii, and M. Alikhani, "Prevalence of class 1, 2 and 3 integrons among extensive drug resistance Acinetobacter baumanii strains isolated from intensive care units in Hamadan, west province, " Iranian Journal of Medical Microbiology, vol. 8, no. 3, pp. 8-14, 2014.
28. M. F. Lin, K. C. Chang, C. Y. Yang et al., "Role of integrons in antimicrobial susceptibility patterns of Acinetobacter baumannii, " Japanese Journal of Infectious Diseases, vol. 63, pp. 440-443, 2010.
29. R. Mirnejad, S. Mostofi, and F. Masjedian, "Antibiotic resistance and carriage class 1 and 2 integrons in clinical isolates of Acinetobacter baumannii from Tehran, Iran, " Asian Pacific Journal of Tropical Biomedicine, vol. 3, no. 2, pp. 140-145, 2013.
30. J. G. M. Koeleman, J. Stoof, M. W. Van der Bijl, C. M. J. E. Vandenbroucke-Grauls, and P. H. M. Savelkoul, "Identification of epidemic strains of Acinetobacter baumannii by integrase gene PCR, " Journal of Clinical Microbiology, vol. 39, no. 1, pp. 8-13, 2001.
31. A. Gaur, P. Prakash, S. Anupurba, and T. M. Mohapatra, "Possible role of integrase gene polymerase chain reaction as an epidemiological marker: study of multidrug-resistant Acinetobacter baumannii isolated from nosocomial infections, " International Journal of Antimicrobial Agents, vol. 29, no. 4, pp. 446-450, 2007.
32. L. L. Maragakis and T. M. Perl, "Acinetobacter baumannii: epidemiology, antimicrobial resistance, and treatment options, " Clinical Infectious Diseases, vol. 46, no. 8, pp. 1254-1263, 2008.