Preparation of [R-(R,S)]-ȕ-methyl-Į-phenyl-1-pyrrolidineethanol: [ 1-Pyrrolidineethanol, ȕ-methyl-Į-phenyl-, [R-(R,S)]- ]

Organic Syntheses

Volumn 77, Issue , 2000, Pages 12-

  Zhao, Dalian ^c   Chen, Cheng yi ^c   Xu, Feng ^c   Tan, Lushi ^c   Tillyer, Richard ^a   Pierce, Michael E ^c   Moore, James R ^b   Burton, Jonathan W ^c   Holmes, Andrew B ^c  

^a MERCK RESEARCH LABORATORIES   (United States)

^b DUPONT COMPANY   (United States)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

EID: 85026859171     PISSN: 00786209     EISSN: 16000730     Source Type: Book Series    
DOI: 10.15227/orgsyn.077.0012     Document Type: Article

References (5)

1. Soai, K.; Yokoyama, S.; Hayasaka, T. J. Org. Chem. 1991, 56, 4264;
2. Niwa, S.; Soai, K. J. Chem. Soc., Perkin Trans. I 1990, 937.
3. Thompson, A. S.; Corley, E. G.; Huntington, M. F.; Grabowski, E. J. J. Tetrahedron Lett. 1995, 36, 8937.
4. Pierce, M. E.; Parsons, Jr., R. L.; Radesca, L. A.; Lo, Y. S.; Silverman, S.; Moore, J. R.; Islam, Q.; Choudhury, A.; Fortunak, J. M. D.; Nguyen, D.; Luo, C.; Morgan, S. J.; Davis, W. P.; Confalone, P. N.; Chen, C.-y.; Tillyer, R. D.; Frey, L.; Tan, L.; Xu, F.; Zhao, D.; Thompson, A. S.; Corley, E. G.; Grabowski, E. J. J.; Reamer, R.; Reider, P. J. J. Org. Chem. 1998, 63, 8536.
5. Synthesis of pyrrolidyl alkanols using NaHCO3 as a base was reported to give pyrrolidyl derivatives in moderate yields. Moffett, R. B. J. Org. Chem. 1949, 14, 862.