Mesenchymal stem cells protect from acute liver injury by attenuating hepatotoxicity of liver natural killer T cells in an inducible nitric oxide synthase- and indoleamine 2,3-dioxygenase-dependent manner

Journal of Tissue Engineering and Regenerative Medicine

Volumn 12, Issue 2, 2018, Pages e1173-e1185

  Gazdic, Marina ^a   Simovic Markovic, Bojana ^a   Vucicevic, Ljubica ^b   Nikolic, Tamara ^a   Djonov, Valentin ^c   Arsenijevic, Nebojsa ^a   Trajkovic, Vladimir ^d   Lukic, Miodrag L ^a   Volarevic, Vladislav ^a  

^a University of Kragujevac Medical Faculty   (Serbia)

^b UNIVERSITY OF BELGRADE   (Serbia)

^c UNIVERSITY OF BERN   (Switzerland)

^d UNIVERSITY OF BELGRADE   (Serbia)

Author keywords

acute liver injury; IDO; immunosuppression; iNOS; mesenchymal stem cells; NKT cells

Indexed keywords

AMINO ACIDS; CELL DEATH; CYTOTOXICITY; DISEASES; FLOWCHARTING; GENE EXPRESSION; GLYCOPROTEINS; MAMMALS; NITRIC OXIDE; STEM CELLS;

ACUTE LIVER INJURY; DIOXYGENASES; IMMUNOSUPPRESSION; INDOLEAMINE 2,3-DIOXYGENASE; INDOLEAMINES; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN-4; MESENCHYMAL STEM CELL; NATURAL KILLER T CELL; TUMOR NECROSIS FACTORS;

CELL CULTURE;

ALPHA GALACTOSYLCERAMIDE; CONCANAVALIN A; FAS LIGAND; GAMMA INTERFERON; INDOLEAMINE 2,3 DIOXYGENASE; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 10; INTERLEUKIN 4; LYSOSOME ASSOCIATED MEMBRANE PROTEIN; N METHYLTRYPTOPHAN; TRANSCRIPTION FACTOR GATA 3; TRANSCRIPTION FACTOR T BET; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; ALPHA-GALACTOSYLCERAMIDE; CYTOKINE; GALACTOSYLCERAMIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; AUTOPHAGY; BIOCHEMICAL ANALYSIS; C57BL 6 MOUSE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOTOXICITY; DOWN REGULATION; FLOW CYTOMETRY; HEP-G2 CELL LINE; HISTOPATHOLOGY; IN VITRO STUDY; IN VIVO STUDY; LIVER CELL; LIVER INJURY; LIVER PROTECTION; LIVER TOXICITY; MALE; MESENCHYMAL STEM CELL; MOUSE; NATURAL KILLER T CELL; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; ANIMAL; C57BL MOUSE; CELL COUNT; CYTOLOGY; GENE EXPRESSION REGULATION; GENETICS; HEPATITIS; HUMAN; IMMUNOLOGY; INJECTION; INJURY; LIVER; MESENCHYMAL STEM CELL TRANSPLANTATION; METABOLISM; MONONUCLEAR CELL; PARACRINE SIGNALING; PATHOLOGY;

ANIMALS; APOPTOSIS; CELL COUNT; CONCANAVALIN A; CYTOKINES; GALACTOSYLCERAMIDES; GENE EXPRESSION REGULATION; HEPATITIS; HUMANS; INDOLEAMINE-PYRROLE 2,3,-DIOXYGENASE; INJECTIONS; LEUKOCYTES, MONONUCLEAR; LIVER; MALE; MESENCHYMAL STEM CELL TRANSPLANTATION; MESENCHYMAL STEM CELLS; MICE, INBRED C57BL; NATURAL KILLER T-CELLS; NITRIC OXIDE SYNTHASE TYPE II; PARACRINE COMMUNICATION;

EID: 85026663864     PISSN: 19326254     EISSN: 19327005     Source Type: Journal    
DOI: 10.1002/term.2452     Document Type: Article

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