High generic drug prices and market competition: A retrospective cohort study

Annals of Internal Medicine

Volumn 167, Issue 3, 2017, Pages 145-151

  Dave, Chintan V ^a   Kesselheim, Aaron S ^a   Fox, Erin R ^a   Qiu, Peihua ^a   Hartzema, Abraham ^a  

^a NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GENERIC DRUG;

ARTICLE; COHORT ANALYSIS; COMPETITION; DRUG COST; DRUG DOSAGE FORM; DRUG MARKETING; FOLLOW UP; PRESCRIPTION; PRIORITY JOURNAL; RETROSPECTIVE STUDY; UNITED STATES; ECONOMIC ASPECT; ECONOMICS; HUMAN;

DRUG COSTS; DRUGS, GENERIC; ECONOMIC COMPETITION; HUMANS; RETROSPECTIVE STUDIES; UNITED STATES;

EID: 85026659541     PISSN: 00034819     EISSN: 15393704     Source Type: Journal    
DOI: 10.7326/M16-1432     Document Type: Article

References (21)

1. Aitken M, Kleinrock M, Lyle J, Caskey L. Dispensed prescriptions for generics and branded generics. In: Medicine Use and Shifting Costs of Healthcare. Danbury, CT: IMS Institute for Healthcare Informatics; 2014:51.
2. Dicken JE; U.S. Government Accountability Office. Letter to Orrin G. Hatch on drug pricing: research on savings from generic drug use. 31 January 2012. Accessed at www.gao.gov/assets/590/588064.pdf on 17 October 2016.
3. Goldman DP, Joyce GF, Zheng Y. Prescription drug cost sharing: associations with medication and medical utilization and spending and health. JAMA. 2007;298:61-9. [PMID: 17609491]
4. Hershman DL, Tsui J, Meyer J, et al. The change from brand-name to generic aromatase inhibitors and hormone therapy adherence for early-stage breast cancer. J Natl Cancer Inst. 2014;106. [PMID: 25349080] doi:10.1093/jnci/dju319
5. Briesacher BA, Andrade SE, Fouayzi H, Chan KA. Medication adherence and use of generic drug therapies. Am J Manag Care. 2009; 15:450-6. [PMID: 19589012]
6. Worth T. The rising cost of generic drugs. Med Econ. 2015;92: 36-9. [PMID: 26299038]
7. Alpern JD, Stauffer WM, Kesselheim AS. High-cost generic drugs-implications for patients and policymakers. N Engl J Med. 2014;371: 1859-62. [PMID: 25390739] doi:10.1056/NEJMp1408376
8. Silverman E. Generic drug prices keep rising, but is a slowdown coming? The Wall Street Journal. Pharmalot Blog. 22 April 2015. Accessed at https://blogs.wsj.com/pharmalot/2015/04/22/generic-drug-prices-keep-rising-but-is-a-slowdown-coming on 17 October 2016.
9. Rosenthal E. Lawmakers look for ways to provide relief for rising cost of generic drugs. The New York Times. 25 November 2014:A17.
10. Gatesman ML, Smith TJ. The shortage of essential chemotherapy drugs in the United States. N Engl J Med. 2011;365:1653-5. [PMID: 22040130] doi:10.1056/NEJMp1109772
11. Truven Analytics. Micromedex: Red Book data set.
12. U.S. Department of Justice; Federal Trade Commission. Horizontal merger guidelines. 2010. Accessed at www.justice.gov/atr/horizontal-merger-guidelines-08192010 on 16 October 2016.
13. Rhoades SA. Herfindahl-Hirschman index. Federal Reserve Bulletin. 1993;79:188.
14. Fox E, Tyler LS. Recent trends in drug shortages: an update from the 2003 report [Letter]. Am J Health Syst Pharm. 2009;66:798-800. [PMID: 19386941] doi:10.2146/ajhp080314
15. U.S. Government Accountability Office (GAO). Public Health Threat Continues Despite Efforts to Help Ensure Product Availability. GAO-14-194. Washington, DC: U.S. GAO; 2014.
16. Kenward MG, Roger JH. Small sample inference for fixed effects from restricted maximum likelihood. Biometrics. 1997;53:983-97. [PMID: 9333350]
17. Morton FM. Entry decisions in the generic pharmaceutical industry. Rand J Econ. 1999;30:421-40. [PMID: 10558596]
18. Increasing Competition in Pharmaceuticals Act, S. 2615, 114th Cong., 2nd Sess. (2016).
19. Generic drug market: growing and merging [Editorial]. Lancet Oncol. 2015;16:595. [PMID: 26065597] doi:10.1016/S1470-2045 (15)70265-2
20. Rockoff JD, Mattioli D, Hoffman L. Teva to buy Allergan Generics for $40.5 billion. The Wall Street Journal. 27 July 2015. Accessed at www.wsj.com/articles/teva-to-buy-allergan-generics-for-40-5-billion -1437988044 on 17 October 2016.
21. Reiffen D, Ward MR. Generic drug industry dynamics. Rev Econ Stat. 2005;87:37-49.