Aggressiveness in depression: a neglected symptom possibly associated with bipolarity and mixed features

Acta Psychiatrica Scandinavica

Volumn 136, Issue 4, 2017, Pages 362-372

  Verdolini, N ^a,b   Perugi, G ^c   Samalin, L ^a,d,e   Murru, A ^a   Angst, J ^f   Azorin, J M ^g   Bowden, C L ^h   Mosolov, S ⁱ   Young, A H ^j   Barbuti, M ^a,c   Guiso, G ^a,k   Popovic, D ^a,l   Vieta, E ^a   Pacchiarotti, I ^a  

^a UNIVERSITY OF BARCELONA   (Spain)

^b UNIVERSITY OF PERUGIA   (Italy)

^c UNIVERSITY OF PISA   (Italy)

^d UNIVERSITY HOSPITAL OF CLERMONT FERRAND   (France)

^e Hopital Albert Chenevier   (France)

^f UNIVERSITY HOSPITAL OF PSYCHIATRY   (Switzerland)

^g ASSISTANCE PUBLIQUE HÔPITAUX DE MARSEILLE   (France)

^h Mays Cancer Center at UT Health San Antonio   (United States)

ⁱ Moscow Research Institute of Psychiatry   (Russian Federation)

^j KING'S COLLEGE LONDON   (United Kingdom)

^k UNIVERSITY OF CAGLIARI   (Italy)

^l SHEBA MEDICAL CENTER   (Israel)

more..

Author keywords

aggressiveness; bipolar disorder; DSM 5 mixed features specifier; major depressive episode

Indexed keywords

ADULT; AGGRESSIVENESS; ARTICLE; BIPOLAR DISORDER; BORDERLINE STATE; CLINICAL FEATURE; COMORBIDITY; CROSS-SECTIONAL STUDY; DISEASE ASSOCIATION; DSM-5; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MAJOR DEPRESSION; MALE; MANIA; MEDICAL HISTORY; POST HOC ANALYSIS; PRIORITY JOURNAL; STUDENT T TEST; SUBSTANCE ABUSE; SUICIDE ATTEMPT; AGGRESSION; CLINICAL TRIAL; MIDDLE AGED; MULTICENTER STUDY; PATHOPHYSIOLOGY; PHYSIOLOGY;

ADULT; AGGRESSION; BIPOLAR DISORDER; BORDERLINE PERSONALITY DISORDER; COMORBIDITY; CROSS-SECTIONAL STUDIES; DEPRESSIVE DISORDER, MAJOR; FEMALE; HUMANS; MALE; MIDDLE AGED;

EID: 85026310369     PISSN: 0001690X     EISSN: 16000447     Source Type: Journal    
DOI: 10.1111/acps.12777     Document Type: Article

References (59)

1. Moyer KE. The psychobiology of aggression. New York: Harper & R; 1976.
2. Safer DJ. Irritable mood and the diagnostic and statistical manual of mental disorders. Child Adolesc Psychiatry Ment Health 2009;3:35.
3. Dolenc B, Dernovšek MZ, Sprah L, Tavcar R, Perugi G, Akiskal HS. Relationship between affective temperaments and aggression in euthymic patients with bipolar mood disorder and major depressive disorder. J Affect Disord 2015;174:13–18.
4. Ballester J, Goldstein B, Goldstein TR et al. Prospective longitudinal course of aggression among adults with bipolar disorder. Bipolar Disord 2014;16:262–269.
5. Ng TH, Freed RD, Titone MK et al. Aggression protects against the onset of major depressive episodes in individuals with bipolar spectrum disorder. Behav Ther 2017;48:311–321.
6. Maj M, Pirozzi R, Magliano L, Bartoli L. Agitated depression in bipolar I disorder: prevalence, phenomenology, and outcome. Am J Psychiatry 2003;160:2134–2140.
7. Sato T, Bottlender R, Kleindienst N, Möller H-J. Syndromes and phenomenological subtypes underlying acute mania: a factor analytic study of 576 manic patients. Am J Psychiatry 2002;159:968–974.
8. Michaelis BH, Goldberg JF, Davis GP, Singer TM, Garno JL, Wenze SJ. Dimensions of impulsivity and aggression associated with suicide attempts among bipolar patients: a preliminary study. Suicide Life Threat Behav 2004;34:172–176.
9. Ballester J, Goldstein T, Goldstein B et al. Is bipolar disorder specifically associated with aggression? Bipolar Disord 2012;14:283–290.
10. Barlow K, Grenyer B, Ilkiw-Lavalle O. Prevalence and precipitants of aggression in psychiatric inpatient units. Aust N Z J Psychiatry 2000;34:967–974.
11. Dervic K, Garcia-Amador M, Sudol K et al. Bipolar I and II versus unipolar depression: clinical differences and impulsivity/aggression traits. Eur Psychiatry 2015;30:106–113.
12. Salloum IM, Cornelius JR, Mezzich JE, Kirisci L. Impact of concurrent alcohol misuse on symptom presentation of acute mania at initial evaluation. Bipolar Disord 2002;4:418–421.
13. Garno JL, Gunawardane N, Goldberg JF. Predictors of trait aggression in bipolar disorder. Bipolar Disord 2008;10:285–292.
14. Cassidy F, Forest K, Murry E, Carroll BJ. A factor analysis of the signs and symptoms of mania. Arch Gen Psychiatry 1998;55:27–32.
15. Pacchiarotti I, Nivoli AMA, Mazzarini L et al. The symptom structure of bipolar acute episodes: in search for the mixing link. J Affect Disord 2013;149:56–66.
16. American Psychiatric Association. Diagnostic and statistical manual of mental disorders. 5th edn. Washington DC: American Psychiatric Association; 2013.
17. American Psychiatric Association. Diagnostic and statistical manual of mental disorders, 3rd edn. Washington DC: American Psychiatric Association; 1980.
18. Vieta E, Valentí M. Mixed states in DSM-5: implications for clinical care, education, and research. J Affect Disord 2013;148:28–36.
19. Vieta E, Grunze H, Azorin J-M, Fagiolini A. Phenomenology of manic episodes according to the presence or absence of depressive features as defined in DSM-5: Results from the IMPACT self-reported online survey. J Affect Disord 2014;156:206–213.
20. Barbuti M, Pacchiarotti I, Vieta E et al. Antidepressant-induced hypomania/mania in patients with major depression: evidence from the BRIDGE-II-MIX study. J Affect Disord 2017;219:187–192.
21. Perugi G, Angst J, Azorin J-M et al. Mixed features in patients with a major depressive episode: the BRIDGE-II-MIX study. J Clin Psychiatry 2015;76:e351–e358.
22. Perugi G, Angst J, Azorin J-M et al. Relationships between mixed features and borderline personality disorder in 2811 patients with major depressive episode. Acta Psychiatr Scand 2016;133:133–143.
23. Popovic D, Vieta E, Azorin J-M et al. Suicide attempts in major depressive episode: evidence from the BRIDGE-II-Mix study. Bipolar Disord 2015;17:795–803.
24. American Psychiatric Association. Diagnostic and statistical manual of mental disorders (4th edn, Text Revision). Washington, DC: American Psychiatric Association; 2000.
25. Endicott J, Spitzer RL, Fleiss JL, Cohen J. The global assessment scale. A procedure for measuring overall severity of psychiatric disturbance. Arch Gen Psychiatry 1976;33:766–771.
26. Spearing MK, Post RM, Leverich GS, Brandt D, Nolen W. Modification of the Clinical Global Impressions (CGI) Scale for use in bipolar illness (BP): the CGI-BP. Psychiatry Res 1997;73:159–171.
27. Angst J, Azorin J-M, Bowden CL et al. Prevalence and characteristics of undiagnosed bipolar disorders in patients with a major depressive episode: the BRIDGE study. Arch Gen Psychiatry 2011;68:791–798.
28. Angst J, Gamma A, Bowden CL et al. Evidence-based definitions of bipolar-I and bipolar-II disorders among 5,635 patients with major depressive episodes in the Bridge Study: validity and comorbidity. Eur Arch Psychiatry Clin Neurosci 2013;263:663–673.
29. Yoo W, Mayberry R, Bae S, Singh K, Peter He Q, Lillard JW. A study of effects of MultiCollinearity in the multivariable analysis. Int J Appl Sci Technol 2014;4:9–19.
30. Corrigan PW, Watson AC. Findings from the National Comorbidity Survey on the frequency of violent behavior in individuals with psychiatric disorders. Psychiatry Res 2005;136:153–162.
31. Grant BF, Stinson FS, Hasin DS et al. Prevalence, correlates, and comorbidity of bipolar I disorder and axis I and II disorders: results from the National Epidemiologic Survey on Alcohol and Related Conditions. J Clin Psychiatry 2005;66:1205–1215.
32. Látalová K. Bipolar disorder and aggression. Int J Clin Pract 2009;63:889–899.
33. Perroud N, Baud P, Mouthon D, Courtet P, Malafosse A. Impulsivity, aggression and suicidal behavior in unipolar and bipolar disorders. J Affect Disord 2011;134:112–118.
34. Angst J, Cui L, Swendsen J et al. Major depressive disorder with subthreshold bipolarity in the national comorbidity survey replication. Am J Psychiatry 2010;167:1194–1201.
35. Angst J, Gamma A, Bowden CL et al. Diagnostic criteria for bipolarity based on an international sample of 5,635 patients with DSM-IV major depressive episodes. Eur Arch Psychiatry Clin Neurosci 2012;262:3–11.
36. Benazzi F, Akiskal HS. How best to identify a bipolar-related subtype among major depressive patients without spontaneous hypomania: superiority of age at onset criterion over recurrence and polarity? J Affect Disord 2008;107:77–88.
37. Solé E, Garriga M, Valentí M, Vieta E. Mixed features in bipolar disorder. CNS Spectr 2017;22:134–140.
38. Takeshima M, Oka T. DSM-5-defined “mixed features” and Benazzi's mixed depression: which is practically useful to discriminate bipolar disorder from unipolar depression in patients with depression? Psychiatry Clin Neurosci 2015;69:109–116.
39. Iwanami T, Maeshima H, Baba H et al. Psychomotor agitation in major depressive disorder is a predictive factor of mood-switching. J Affect Disord 2015;170:185–189.
40. McIntyre RS, Soczynska JK, Cha DS et al. The prevalence and illness characteristics of DSM-5-defined “mixed feature specifier” in adults with major depressive disorder and bipolar disorder: results from the International Mood Disorders Collaborative Project. J Affect Disord 2015;172:259–264.
41. Azorin J-M, Kaladjian A, Adida M et al. Self-assessment and characteristics of mixed depression in the French national EPIDEP study. J Affect Disord 2012;143:109–117.
42. Sani G, Napoletano F, Vöhringer PA et al. Mixed depression: clinical features and predictors of its onset associated with antidepressant use. Psychother Psychosom 2014;83:213–221.
43. Koukopoulos A, Sani G, Koukopoulos AE, Manfredi G, Pacchiarotti I, Girardi P. Melancholia agitata and mixed depression. Acta Psychiatr Scand Suppl 2007;115:50–57.
44. Vieta E, Garriga M. Adjunctive antidepressants in bipolar depression. Lancet Psychiatry 2016;3:1095–1096.
45. Pacchiarotti I, Bond DJ, Baldessarini RJ et al. The International Society for Bipolar Disorders (ISBD) task force report on antidepressant use in bipolar disorders. Am J Psychiatry 2013;170:1249–1262.
46. Swann AC, Lijffijt M, Lane SD, Steinberg JL, Moeller FG. Interactions between bipolar disorder and antisocial personality disorder in trait impulsivity and severity of illness. Acta Psychiatr Scand 2010;121:453–461.
47. Oquendo MA, Waternaux C, Brodsky B et al. Suicidal behavior in bipolar mood disorder: clinical characteristics of attempters and nonattempters. J Affect Disord 2000;59:107–117.
48. Oquendo MA, Galfalvy H, Russo S et al. Prospective study of clinical predictors of suicidal acts after a major depressive episode in patients with major depressive disorder or bipolar disorder. Am J Psychiatry 2004;161:1433–1441.
49. Carli V, Jovanović N, Podlesek A et al. The role of impulsivity in self-mutilators, suicide ideators and suicide attempters – a study of 1265 male incarcerated individuals. J Affect Disord 2010;123:116–122.
50. Mann JJ, Arango VA, Avenevoli S et al. Candidate endophenotypes for genetic studies of suicidal behavior. Biol Psychiatry 2009;65:556–563.
51. Reinares M, del Mar Bonnín C, Hidalgo-Mazzei D et al. Making sense of DSM-5 mania with depressive features. Aust New Zeal J Psychiatry 2015;49:540–549.
52. Benazzi F. Reviewing the diagnostic validity and utility of mixed depression (depressive mixed states). Eur Psychiatry 2008;23:40–48.
53. Stahl SM, Morrissette DA, Cummings M et al. California state hospital violence assessment and treatment (Cal-VAT) guideline. CNS Spectr 2014;19:449–465.
54. Garriga M, Pacchiarotti I, Kasper S et al. Assessment and management of agitation in psychiatry: Expert consensus. World J Biol Psychiatry 2016;17:86–128.
55. Goodwin G, Haddad P, Ferrier I et al. Evidence-based guidelines for treating bipolar disorder: revised third edition recommendations from the British Association for Psychopharmacology. J Psychopharmacol 2016;30:495–553.
56. Sahlin H, Kuja-Halkola R, Bjureberg J et al. Association between deliberate self-harm and violent criminality. JAMA Psychiatry 2017;74:615–621.
57. Verdolini N, Murru A, Attademo L et al. The aggressor at the mirror: psychiatric correlates of deliberate self-harm in male prison inmates. Eur Psychiatry 2017;44:153–160.
58. Vieta E. Antidepressants in bipolar I disorder: never as monotherapy. Am J Psychiatry 2014;171:1023–1026.
59. Allen DM, Parry PI, Purssey R et al. BRIDGE study warrants critique. Arch Gen Psychiatry 2012;69:643–644.