Emergence of Livestock-Associated Methicillin-Resistant Staphylococcus aureus Bloodstream Infections in Denmark

Clinical Infectious Diseases

Volumn 65, Issue 7, 2017, Pages 1072-1076

  Larsen, Jesper ^a   Petersen, Andreas ^a   Larsen, Anders R ^a   Sieber, Raphael N ^a   Stegger, Marc ^a,b   Koch, Anders ^a   Aarestrup, Frank M ^c   Price, Lance B ^b,d   Skov, Robert L ^a   Johansen, Helle Krogh ^e   Westh, Henrik ^f   Pedersen, Michael ^g   Jensen, Ulrich Stab ^h   Jensen, Marie Louise Slott ⁱ   Chen, Ming ^j   Strøbæk, Steffen ^k   Østergaard, Claus ^l   Lomborg, Steen ^l   Ellermann Eriksen, Svend ^m   Ripadal, Pernille ⁿ  

^a STATENS SERUM INSTITUT   (Denmark)

^b TRANSLATIONAL GENOMICS RESEARCH INSTITUTE   (United States)

^c TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

^d GEORGE WASHINGTON UNIVERSITY   (United States)

^e University of Copenhagen   (Denmark)

^f HVIDOVRE HOSPITAL   (Denmark)

^g GENTOFTE UNIVERSITY HOSPITAL   (Denmark)

^h SLAGELSE HOSPITAL   (Denmark)

ⁱ ODENSE UNIVERSITY HOSPITAL   (Denmark)

^j Sonderborg Hospital   (Denmark)

^k Hospital South West Jutland ^*  (Denmark)

^l LILLEBAELT HOSPITAL   (Denmark)

^m AARHUS UNIVERSITY HOSPITAL   (Denmark)

ⁿ AALBORG UNIVERSITY HOSPITAL   (Denmark)

more..

Author keywords

bacteremia; humans; livestock; MRSA; zoonosis

Indexed keywords

LANTHANUM;

ADULT; AGED; ARTICLE; BACTEREMIA; BACTERIUM ISOLATE; BLOODSTREAM INFECTION; CASE FATALITY RATE; CHARLSON COMORBIDITY INDEX; CHILD; CLINICAL ARTICLE; DENMARK; FEMALE; HUMAN; IMMUNOCOMPROMISED PATIENT; INFANT; LIVESTOCK; MALE; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS INFECTION; MIDDLE AGED; NONHUMAN; PHYLOGENY; PIG; POULTRY MEAT; PRESCHOOL CHILD; PRIORITY JOURNAL; RURAL AREA; SEQUENCE ANALYSIS; SINGLE NUCLEOTIDE POLYMORPHISM; SKIN INFECTION; SOFT TISSUE INFECTION; STAPHYLOCOCCUS INFECTION; URBAN AREA; VERY ELDERLY; WHOLE GENOME SEQUENCING; ANIMAL; GENETICS; MICROBIOLOGY; NEWBORN; PROCEDURES; STAPHYLOCOCCAL SKIN INFECTION; ZOONOSIS;

ADULT; AGED; AGED, 80 AND OVER; ANIMALS; BACTEREMIA; CHILD; DENMARK; FEMALE; HUMANS; INFANT, NEWBORN; LIVESTOCK; MALE; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; MIDDLE AGED; PHYLOGENY; SOFT TISSUE INFECTIONS; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCAL SKIN INFECTIONS; SWINE; WHOLE GENOME SEQUENCING; ZOONOSES;

EID: 85025134651     PISSN: 10584838     EISSN: 15376591     Source Type: Journal    
DOI: 10.1093/cid/cix504     Document Type: Article

References (21)

1. Larsen J, Petersen A, Sørum M, et al. Methicillin-resistant Staphylococcus aureus CC398 is an increasing cause of disease in people with no livestock contact in Denmark. Euro Surveill 2015; 20. doi:10.2807/1560-7917. ES.2015.20.37.30021.
2. van Cleef BA, Monnet DL, Voss A, et al. Livestock-associated methicillin-resistant Staphylococcus aureus in humans, Europe. Emerg Infect Dis 2011; 17:502-5.
3. EPI-NYT. MRSA CC398-epidemiologien i Danmark. Danish. Available at: http:// www.ssi.dk/Aktuelt/Nyhedsbreve/EPI-NYT/2014/Uge%2024a%20-%202014. aspx. Accessed 4 April 2016.
4. Larsen AR, Stegger M, Sørum M. spa typing directly from a mecA, spa and pvl multiplex PCR assay-a cost-effective improvement for methicillin-resistant Staphylococcus aureus surveillance. Clin Microbiol Infect 2008; 14:611-4.
5. Quan H, Li B, Couris CM, et al. Updating and validating the Charlson comorbidity index and score for risk adjustment in hospital discharge abstracts using data from 6 countries. Am J Epidemiol 2011; 173:676-82.
6. Statistics Denmark. Population and elections. Available at: http://www.dst.dk/en/ Statistik/emner?subject=02. Accessed 4 December 2016.
7. Danish Integrated Antimicrobial Resistance Monitoring and Research Programme. DANMAP 2010: use of antimicrobial agents and occurrence of antimicrobial resistance in bacteria from food animals, food and humans in Denmark. Available at: http://danmap.org/~/media/Projekt%20sites/Danmap/ DANMAP%20reports/Danmap-2010.ashx. Accessed 4 December 2016.
8. Danish Integrated Antimicrobial Resistance Monitoring and Research Programme. DANMAP 2014: use of antimicrobial agents and occurrence of antimicrobial resistance in bacteria from food animals, food and humans in Denmark. Available at: http://danmap.org/~/media/Projekt%20sites/Danmap/ DANMAP%20reports/DANMAP%202014/Danmap-2014.ashx. Accessed 4 December 2016.
9. Price LB, Stegger M, Hasman H, et al. Staphylococcus aureus CC398: host adaptation and emergence of methicillin resistance in livestock. mBio 2012; 3:e00305-11.
10. Hallin M, De Mendonça R, Denis O, et al. Diversity of accessory genome of human and livestock-associated ST398 methicillin resistant Staphylococcus aureus strains. Infect Genet Evol 2011; 11:290-9.
11. Argudín MA, Tenhagen BA, Fetsch A, et al. Virulence and resistance determinants of German Staphylococcus aureus ST398 isolates from nonhuman sources. Appl Environ Microbiol 2011; 77:3052-60.
12. Larsen J, Stegger M, Andersen PS, et al. Evidence for human adaptation and foodborne transmission of livestock-associated methicillin-resistant Staphylococcus aureus. Clin Infect Dis 2016; 63:1349-52.
13. Grøntvedt CA, Elstrøm P, Stegger M, et al. Methicillin-resistant Staphylococcus aureus CC398 in humans and pigs in Norway: a One Health perspective on introduction and transmission. Clin Infect Dis 2016; 63:1431-8.
14. Nielsen RT, Kemp M, Holm A, et al. Fatal septicemia linked to transmission of MRSA clonal complex 398 in hospital and nursing home, Denmark. Emerg Infect Dis 2016; 22:900-2.
15. Wulf MW, Markestein A, van der Linden FT, Voss A, Klaassen C, Verduin CM. First outbreak of methicillin-resistant Staphylococcus aureus ST398 in a Dutch hospital, June 2007. Euro Surveill 2008; 13. pii:8051.
16. Fanoy E, Helmhout LC, van der Vaart WL, et al. An outbreak of non-typeable MRSA within a residential care facility. Euro Surveill 2009; 14. pii:19080.
17. Verkade E, Bosch T, Hendriks Y, Kluytmans J. Outbreak of methicillin-resistant Staphylococcus aureus ST398 in a Dutch nursing home. Infect Control Hosp Epidemiol 2012; 33:624-6.
18. Chuang YY, Huang YC. Livestock-associated meticillin-resistant Staphylococcus aureus in Asia: an emerging issue? Int J Antimicrob Agents 2015; 45:334-40.
19. Smith TC. Livestock-associated Staphylococcus aureus: the United States experience. PLoS Pathog 2015; 11:e1004564.
20. European Centre for Disease Prevention and Control. Antimicrobial resistance surveillance in Europe 2014. Annual Report of the European Antimicrobial Resistance Surveillance Network (EARS-Net). Stockholm: ECDC; 2015.
21. Petersen A, Skov RL, Larsen AR; Danish Staphylococcus aureus bacteraemia group. Staphylococcus aureus bacteraemia cases in Denmark 2014. Available at: http://www. ssi.dk/~/media/Indhold/DK%20-%20dansk/Smitteberedskab/Referencelaboratorier/ Stafylokoklaboratoriet/SAB%202014.ashx. Accessed 4 December 2016.