I-FABP is a Novel Marker for the Detection of Intestinal Injury in Severely Injured Trauma Patients

World Journal of Surgery

Volumn 41, Issue 12, 2017, Pages 3120-3127

  Voth, M ^a   Duchene, M ^a   Auner, B ^a   Lustenberger, T ^a   Relja, B ^a   Marzi, I ^a  

^a GOETHE UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; FATTY ACID BINDING PROTEIN;

ABDOMINAL INJURY; ADULT; BLOOD; CASE CONTROL STUDY; COMPLICATION; FEMALE; HUMAN; INJURIES; INJURY SCALE; INTESTINE; MALE; MIDDLE AGED; RETROSPECTIVE STUDY; TIME FACTOR;

ABBREVIATED INJURY SCALE; ABDOMINAL INJURIES; ADULT; BIOMARKERS; CASE-CONTROL STUDIES; FATTY ACID-BINDING PROTEINS; FEMALE; HUMANS; INJURY SEVERITY SCORE; INTESTINES; MALE; MIDDLE AGED; RETROSPECTIVE STUDIES; TIME FACTORS;

EID: 85024488863     PISSN: 03642313     EISSN: 14322323     Source Type: Journal    
DOI: 10.1007/s00268-017-4124-2     Document Type: Article

References (53)

1. ® (2014) TR-DGU der Sektion NIS. www.traumaregister.de
2. Nast-Kolb D, Waydhas C, Kastl S et al (1993) The role of an abdominal injury in follow-up of polytrauma patients. Chirurg 64:552–559
3. Heuer M, Hussmann B, Kaiser G et al (2012) Hollow organ injury and multiple trauma: treatment, course and outcome—an organ-specific evaluation of 1127 patients from the trauma registry of the DGU. Zentralbl Chir 139:445–451
4. Allen GS, Moore FA, Cox CS et al (1998) Hollow visceral injury and blunt trauma. J Trauma 45:69–75
5. Enderson BL, Maull KI (1991) Missed injuries. The trauma surgeon’s nemesis. Surg Clin North Am 71:399–418
6. Schumpelick V, Ambacher T, Riesener KP (1999) Current therapy of injuries of the colon and retroperitoneum. Chirurg 70:1269–1277
7. Osborn TM, Tracy JK, Dunne JR et al (2005) Epidemiology of sepsis in patients with traumatic injury. Crit Care Med 32:2234–2240
8. Shebrain S, Zelada J, Lipsky AM et al (2006) Mesenteric injuries after blunt abdominal trauma: delay in diagnosis and increased morbidity. Am Surg 72:955–961
9. Sung CK, Kim KH (1996) Missed injuries in abdominal trauma. J Trauma 41:276–282
10. Niederee MJ, Byrnes MC, Helmer SD et al (2003) Delay in diagnosis of hollow viscus injuries: effect on outcome. Am Surg 69:293–299
11. Malinoski DJ, Patel MS, Yakar DO et al (2010) A diagnostic delay of 5 hours increases the risk of death after blunt hollow viscus injury. J Trauma 69:84–87
12. Helling TS, Wilson J, Augustosky K (2007) The utility of focused abdominal ultrasound in blunt abdominal trauma: a reappraisal. Am J Surg 194:728
13. Liu M, Lee CH, P’eng FK (1993) Prospective comparison of diagnostic peritoneal lavage, computed tomographic scanning, and ultrasonography for the diagnosis of blunt abdominal trauma. J Trauma 35:267–270
14. Tajoddini S, Vahdati SS (2013) Ultrasonographic diagnosis of abdominal free fluid: accuracy comparison of emergency physicians and radiologists. Eur J Trauma Emerg Surg 39:9–13
15. Sherck J, Shatney C, Sensaki K et al (1994) The accuracy of computed tomography in the diagnosis of blunt small-bowel perforation. Am J Surg 168:670–675
16. Hefny AF, Kunhivalappil FT, Matev N et al (2014) Usefulness of free intraperitoneal air detected by CT scan in diagnosing bowel perforation in blunt trauma: experience from a community-based hospital. Injury 46:100–104
17. Joseph DK, Kunac A, Kinler RL et al (2013) Diagnosing blunt hollow viscus injury: is computed tomography the answer? Am J Surg 205:414–418
18. Park M-H, Shin BS, Namgung H (2013) Diagnostic performance of 64-MDCT for blunt small bowel perforation. Clin Imaging 37:884–888
19. Bège T, Chaumoître K, Léone M, Mancini J (2014) Blunt bowel and mesenteric injuries detected on CT scan: who is really eligible for surgery? Eur J Trauma Emerg Surg 40:75–81
20. Bishop-Bartolomei K, Babineau TJ (2005) The role of computed tomography scanning in abdominal trauma: an update. Curr Surg 62:549
21. Glatz JF, van der Vusse GJ (1996) Cellular fatty acid-binding proteins: their function and physiological significance. Prog Lipid Res 35:243–282
22. Pelsers MMAL, Hermens WT, Glatz JFC (2005) Fatty acid-binding proteins as plasma markers of tissue injury. Clin Chim Acta 352:15–35
23. Chan CPY, Wan TSM, Watkins KL et al (2004) Rapid analysis of fatty acid-binding proteins with immunosensors and immunotests for early monitoring of tissue injury. Biosens Bioelectron 20:2566–2580
24. Flower DR (1996) The lipocalin protein family: structure and function. Biochem J 318(Pt 1):1–14
25. Banaszak L, Winter N, Xu Z et al (1994) Lipid-binding proteins: a family of fatty acid and retinoid transport proteins. Adv Protein Chem 45:89–151
26. Pelsers MMAL, Namiot Z, Kisielewski W et al (2003) Intestinal-type and liver-type fatty acid-binding protein in the intestine. Tissue distribution and clinical utility. Clin Biochem 36:529–535
27. Edelson MB, Sonnino RE, Bagwell CE et al (1999) Plasma intestinal fatty acid binding protein in neonates with necrotizing enterocolitis: a pilot study. J Pediatr Surg 34:1453–1457
28. Heida FH, Hulscher JBF, Schurink M et al (2014) Intestinal fatty acid-binding protein levels in Necrotizing Enterocolitis correlate with extent of necrotic bowel: results from a multicenter study. J Pediatr Surg 50:1115–1118
29. Guthmann F, Börchers T, Wolfrum C et al (2002) Plasma concentration of intestinal- and liver-FABP in neonates suffering from necrotizing enterocolitis and in healthy preterm neonates. Mol Cell Biochem 239:227–234
30. Kanda T, Tsukahara A, Ueki K et al (2011) Diagnosis of ischemic small bowel disease by measurement of serum intestinal fatty acid-binding protein in patients with acute abdomen: a multicenter, observer-blinded validation study. J Gastroenterol 46:492–500
31. Kanda T, Fujii H, Fujita M et al (1995) Intestinal fatty acid binding protein is available for diagnosis of intestinal ischaemia: immunochemical analysis of two patients with ischaemic intestinal diseases. Gut 36:788–791
32. Shi H, Wu B, Wan J et al (2015) The role of serum intestinal fatty acid binding protein levels and D-lactate levels in the diagnosis of acute intestinal ischemia. Clin Res Hepatol Gastroenterol 39:373–378
33. Cronk DR, Houseworth TP, Cuadrado DG et al (2006) Intestinal fatty acid binding protein (I-FABP) for the detection of strangulated mechanical small bowel obstruction. Curr Surg 63:322–325
34. Timmermans K, Sir Ö, Kox M et al (2014) Circulating iFABP Levels as a marker of intestinal damage in trauma patients. Shock 43:117–120
35. Voth M, Holzberger S, Auner B et al (2014) I-FABP and L-FABP are early markers for abdominal injury with limited prognostic value for secondary organ failures in the post-traumatic course. Clin Chem Lab Med 53:771–780
36. Relja B, Szermutzky M, Henrich D et al (2010) Intestinal-FABP and liver-FABP: novel markers for severe abdominal injury. Acad Emerg Med 17:729–735
37. von Elm E, Altman DG, Egger M et al (2014) The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies. Int J Surg 12:1495–1499
38. Baker SP, O’Neill B, Haddon W, Long WB (1974) The injury severity score: a method for describing patients with multiple injuries and evaluating emergency care. J Trauma 14:187–196
39. Barrington I (1998) The Abbreviated Injury Scale 1990 revision—update 1998. Association for the Advancement of Automotive Medicine
40. Reinhart K, Brunkhorst FM, Bone HG et al (2006) Diagnose und Therapie der Sepsis. Intensivmed Notfallmed 43:369–384
41. Vincent JL, Moreno R, Takala J et al (1996) The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction/failure. Intensive Care Med 22:707–710
42. Le Gall JR, Lemeshow S, Saulnier F (1993) A new simplified acute physiology score (SAPS II) based on a European/North American multicenter study. JAMA 270:2957–2963
43. Bernard GR, Artigas A, Brigham KL (1994) The American-European consensus conference on ARDS definitions, mechanisms, relevant outcomes, and clinical trial coordination. Am J Respir Crit Care Med 149:818–824
44. Dalhoff K, Abele M (2012) Epidemiology, diagnosis and treatment of adult patients with nosocomial pneumonia. S-3 Guideline of the German Society for Anaesthesiology and Intensive Care Medicine, the German Society for Infectious Diseases, the German Society for Hygiene and Microbiology, the German Respiratory Society and the Paul-Ehrlich-Society for Chemotherapy. Pneumologie 66:707–765
45. Watts DD, Fakhry SM (2003) Incidence of hollow viscus injury in blunt trauma: an analysis from 275,557 trauma admissions from the East multi-institutional trial. J Trauma 54:289–294
46. Longo WE, Degutis LC, Baker CC (1989) Blunt hollow viscus injuries of the digestive tract: a poorly recognized phenomenon. Conn Med 53:451–454
47. Pal JD, Victorino GP (2002) Defining the role of computed tomography in blunt abdominal trauma: use in the hemodynamically stable patient with a depressed level of consciousness. Arch Surg 137:1029–1033
48. Schellekens DHSM, Grootjans J, Dello SAWG et al (2013) Plasma intestinal fatty acid-binding protein levels correlate with morphologic epithelial intestinal damage in a human translational ischemia-reperfusion model. J Clin Gastroenterol 48:253–260
49. Derikx JPM, Poeze M, van Bijnen AA et al (2007) Evidence for intestinal and liver epithelial cell injury in the early phase of sepsis. Shock 28:544–548
50. Ockner RK, Manning JA, Poppenhausen RB, Ho WK (1972) A binding protein for fatty acids in cytosol of intestinal mucosa, liver, myocardium, and other tissues. Science 177:56–58
51. Derikx JPM, Vreugdenhil ACE, Van den Neucker AM et al (2009) A pilot study on the noninvasive evaluation of intestinal damage in celiac disease using I-FABP and L-FABP. J Clin Gastroenterol 43:727–733
52. Uludağ M, Yetkin G, Citgez B et al (2009) Effects of additional intra-abdominal organ injuries in patients with penetrating small bowel trauma on morbidity and mortality. Ulus Travma Acil Cerrahi Derg 15:45–51
53. Matsumoto S, Sekine K, Funaoka H et al (2016) Clinical evaluation of “shock bowel” using intestinal fatty acid binding protein. Shock 47:100–106