Identification of a Shigella Flexneri criR Gene Increasing ipa Genes Expression: A novel member of response regulators of the two-component signal transduction family

Japanese Journal of Medical Science and Biology

Volumn 49, Issue 42496, 1996, Pages 219-239

  Ming Shan, Q I ^a   Watanabe, Haruo ^a   Yoshikura, Hiroshi ^b  

^a NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; PROTEIN;

ARTICLE; BACTERIAL GENE; ESCHERICHIA COLI; GENE EXPRESSION; GENE ISOLATION; GENE LOCUS; GENE MAPPING; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; SEQUENCE HOMOLOGY; SHIGELLA FLEXNERI; SIGNAL TRANSDUCTION; TRANSPOSON;

EID: 85024441670     PISSN: 00215112     EISSN: None     Source Type: Journal    
DOI: 10.7883/yoken1952.49.219     Document Type: Article

References (37)

1. Labrec, E. H., Schneider, H., Magnani, T. J. and Formai, S. B. (1964): Epithelial cell penetration as an essential step in the pathogenesis of bacillary dysentery. J. Bacateriol., 88, 1503-1518.
2. Hale, T. L. (1991): Genetic basis of virulence in Shigella species. Microbiol. Rev., 55, 206-224.
3. Sansonetti, P. J., Halte, T. L., Dammin, G. J., Kapfer, C., Collins, H. H. and Formal, S. B. (1983): Alterations in the pathogenicity of Escherichia coli K-12 after transfer of plasmid and chromosomal genes from Shigella flexneri. Infect. Immun., 39, 1392-1402.
4. Sansonotti, P. J., D'Hauteville, H., Ecobichon, C. and Pourcel, C. (1983): Molecular comparison of virulence plasmids in Shigella and enteroinvasive Escherichia coli. Ann. Microbiol. (Paris), 134A, 295-318.
5. Maurelli, A. T., Baudry, B., D'Hauteville, H., Hale, T. L. and Sansonetti, P. J. (1985): Cloning of plasmid DNA sequences involved in invasion of HeLa cells by Shigella ñexneri. Infect. Immun., 49, 164-171.
6. Kato, J., Ito, K., Nakamura, A. and Watanabe, H. (1989): Cloning of regions required for contact hemolysis and entry into LLC-MK2 cells from Shigella sonnei form I plasmid: virF is a positive regulator gene for these phenotypes. Infect. Immun., 57, 1391-1398.
7. Hale, T. L., Oaks, E. V. and Formal, S. B. (1985): Identification and antigenic characterization of virulence-associated, plasmid-coded proteins of Shigella spp. and enteroinvasive Escherichia coli. Infect. Immun., 50, 620-629.
8. Venkatesan, M. M., Buysse, J. M. and Oaks, E. V. (1992): Surface presentation of Shigella flexneri invasion plasmid antigens requires the products of the spa locus. J. Bacteriol., 174, 1990-2001.
9. Andrews, G. P., Hromockyj, A. E., Coker, C. and Maurelli, A. T. (1991): Two novel virulence loci, mxiA and mxiB, in Shigella flexneri 2a facilitate excretion of invasion plasmid antigens. Infect. Immun., 59, 1997-2005.
10. Allaoui, A., Sansonetti, P. J. and Parsot, C. (1992): MxiJ, a lipoprotein involved in secretion of Shigella Ipa invasions, is homologous to YscJ, a secretion factor of the Yersinia Yop proteins. J. Bacteriol., 174, 7661-7669.
11. Allaoui, A., Sansonetti, P. J. and Parsot, C. (1993): MxiD, an outer membrane protein necessary for the secretion of the Shigella flexneri Ipa invasins. Mol. Microbiol., 7, 59-1768.
12. Sasakawa, C., Komatsu, K., Tobe, T., Suzuki, T. and Yoshikawa, M. (1993): Eight genes in region 5 that form an operon are essential for invasion of epithelial cells by Shigella flexneri 2a. J. Bacteriol., 175, 2334-2346.
13. Venkatesan, M. M., Buysse, J. M. and Kopecko, D. J. (1988): Characterization of invasion plasmid antiagen genes (ipaBCD) from Shigella flexneri. Proc. Natl. Acad. Sci. USA, 85, 9317-9321.
14. Adler, B., Sasakawa, C., Tobe, T., Makin, S., Komatsu, K. and Yoshikawa, M. (1989): A dual transcriptional activation system for the 230 kb plasmid genes coding for virulence-associated antigens of Shigella flexneri. Mol. Microbiol., 3, 627-635.
15. High, N., Mounier, J., Prevost, M. C. and Sansonetti, P. J. (1992): IpaB of Shigella flexneri causes entry into epithelial cells and escape from the phagocytic vacuole. EMBO J., 11, 1991-1999.
16. Sakai, T., Sasakawa C. and Yoshikawa, M. (1988): Expression of four virulence antigens of Shigella flexneri is positively regulated at the transcriptional level by the 30 kiloDalton virF protein. Mol. Microbiol., 2, 589-597.
17. Watanabe, H., Arakawa, E., Ito, K., Kato, J. and Nakamura, A. (1990): Genetic analysis of an invasion region by use of a Tn3-lac transposon and identification of a second positive regulator gene, invE, for cell invasion of Shigella sonnei: significant homology of invE with ParB or plasmid P1. J. Bacteriol., 172, 619-629.
18. Bernardini, M. L., Fontaine, A. and Sansonetti, P. J. (1990): The twocomponent regulatory system ompR-envZ controls the virulence of Shigella flexneri. J. Bacteriol., 172, 6274-6281.
19. Maurelli, A. T. and Sansonetti, P. J. (1988): Identification of a chromosomal gene controlling temperature-regulated expression of Shigella virulence. Proc. Natl. Acad. Sci. USA, 85, 2820-2824.
20. Tobe, T., Yoshikawa, M., Mizuno, T. and Sasakawa, C. (1993): Transcriptional control of the invasion regulatory gene virB of Shigella flexneri: activation by virF and repression by H-NS. J. Bacteriol., 175, 6142-6149.
21. Hromockyj, A. E., Tucker, S. C. and Maurelli, A. T. (1992): Temperature regulation of Shigella virulence: identification of the repressor gene virR, an analogue of hns, and partial complementation by tyrosyl transfer RNA (tRNAl(Tyr)). Mol. Microbiol., 6, 2113-2124.
22. Nakayama, S. and Watanabe, H. (1995): Involvement of cpxA, a sensor of a two-component regulatory system, in the pH-dependent regulation of expression of Shigella sonnei virF gene. J. Bacteriol., 177, 5062-5069.
23. Maniatis, T., Fritsch, E. F. and Sambrook, J. (1982): Molecular cloning: a laboratory manual. Cold Spring Harbor Laboratory, Cold Sprin Harbor, New York, NY.
24. Watanabe, H. and Nakamura, A. (1985): Large plasmids associated with virulence in Shigella species have a common function necessary for epithelial cell penetration. Infect. Immun., 48, 260-262.
25. Miller, J. H. (1972): Experiments in molecular genetics. Cold Spring Harbor Laboratory. Cold Spring Harbor, New York, NY.
26. Sasakawa, C. and Yoshikawa, M. (1987): A series of Tn5 variants with various drug-resistence markers and suicide vector for transposon mutagenesis. Gene, 56, 283-288.
27. Southern, E. M. (1975): Detection of specific sequence among DNA fragments separated by gel electrophoresis. J. Mol. Biol., 98, 503-517.
28. Aiba, H., Adhya, S. and De Crombrugghe, B. (1981): Evidence for two functional gal promoters in intact Escherichia coli cells. J. Biol. Chem., 256, 11905-11910.
29. Rosen, K. M. (1989): An alternative method for the visualization of RNA in formaldehyde agarose gels. Focus, 12, 23-24.
30. Kohara, Y., Akiyama, K. and Isono, K. (1987): The physical map of the whole E. coli chromosome: application of a new strategy for rapid analysis and sorting of a large genomic library. Cell, 50, 495-508.
31. Sasakawa, C., Adler, B., Tobe, T., Okada, N., Nagai, S., Komatsu, K. and Yoshikawa, M. (1989): Functional organization and nucleotide sequence of virulence Region-2 on the large virulence plasmid in Shigella flexneri 2a. Mol. Microbiol., 3, 1191-1201.
32. Stock, J. B., Ninfa, A. J. and Stock, A. M. (1989): Protein phosphorylation and regulation of adaptive responses in bacteria. Microbiol. Rev., 53, 450-490.
33. Noda, A., Courtright, J. B., Denor, P. F., Webb, G., Kohara, Y. and Ishihama, A. (1991): Rapid identification of specific genes in E. coli by hybridization to membranes containing the ordered set of phage clones. Biotechiniques, 10, 474, 476-477.
34. Tobe, T., Sasakawa, C., Okada, N., Honma, Y. and Yoshikawa, M. (1992): vacB, a novel chromosomal gene required for expression of virulence genes on the large plasmid of Shigella flexneri. J. Bacteriol., 174, 6359-6367.
35. Watanabe, H. and Nakamura, A. (1986): Identification of Shigella sonnei form I plasmid genes necessary for cell invasion and their conservation among Shigella species and enteroinvasive Escherichia coli. Infect. Immun., 53, 352-358.
36. Chang, A. C. and Cohen, S. N. (1978): Construction and characterization of amplifiable multicopy DNA cloning vehicles derived from the P154 crytpic miniplasmid. J. Bacteriol., 134, 1141-1156.
37. Martinez, E., Bartolome, B. and De la Cruz, F. (1988): pACYC184-derived cloning vectors containing the multiple cloning site and lacZ alpha reporter gene of pUC8/9 and pUC18/19 plasmids. Gene, 68, 159-162.