메뉴 건너뛰기




Volumn 17, Issue 1, 2017, Pages

Cytotoxic activity of extracts and crude saponins from Zanthoxylum armatum DC. against human breast (MCF-7, MDA-MB-468) and colorectal (Caco-2) cancer cell lines

Author keywords

Breast cancer; Colorectal cancer; DAPI; MTT; NRU; Saponins; Zanthoxylum armatum

Indexed keywords

ANTINEOPLASTIC AGENT; DACTINOMYCIN; METHANOL; PLANT EXTRACT; SAPONIN; UNCLASSIFIED DRUG; ZANTHOXYLUM ARMATUM EXTRACT; CHROMATIN;

EID: 85024105326     PISSN: None     EISSN: 14726882     Source Type: Journal    
DOI: 10.1186/s12906-017-1882-1     Document Type: Article
Times cited : (61)

References (31)
  • 1
    • 0031028432 scopus 로고    scopus 로고
    • Natural products in drug discovery and development
    • Cragg GM, Newman DJ, Snader KM. Natural products in drug discovery and development. J Nat Prod. 1997;60(1):52-60.
    • (1997) J Nat Prod , vol.60 , Issue.1 , pp. 52-60
    • Cragg, G.M.1    Newman, D.J.2    Snader, K.M.3
  • 3
    • 84893855917 scopus 로고    scopus 로고
    • Aqueous extracts of dried fruits of Zanthoxylum armatum DC.,(Rutaceae) induce cellular and nuclear damage coupled with inhibition of mitotic activity in vivo
    • Kharshiing EV. Aqueous extracts of dried fruits of Zanthoxylum armatum DC.,(Rutaceae) induce cellular and nuclear damage coupled with inhibition of mitotic activity in vivo. Amer J Plant Sci. 2012;3(11):1646.
    • (2012) Amer J Plant Sci , vol.3 , Issue.11 , pp. 1646
    • Kharshiing, E.V.1
  • 4
    • 84876488890 scopus 로고    scopus 로고
    • Zanthoxylum Usambarense (Engl.) Kokwaro (Rutaceae) extracts inhibit the growth of the breast cancer cell lines MDA-MB-231 and MCF-7, but not the brain tumour cell line U251 in vitro
    • Özkan M, et al. Zanthoxylum Usambarense (Engl.) Kokwaro (Rutaceae) extracts inhibit the growth of the breast cancer cell lines MDA-MB-231 and MCF-7, but not the brain tumour cell line U251 in vitro. Phytother Res. 2013;27(5):787-90.
    • (2013) Phytother Res , vol.27 , Issue.5 , pp. 787-790
    • Özkan, M.1
  • 5
    • 0003702402 scopus 로고    scopus 로고
    • Glossary of Indian medicinal plants, national institute of science communication and information resources
    • New Delhi: CSIR.
    • Chopra R, Nayar S, Chopra I. Glossary of Indian medicinal plants, national institute of science communication and information resources. New Delhi: CSIR; 2006.
    • (2006)
    • Chopra, R.1    Nayar, S.2    Chopra, I.3
  • 6
    • 0015403403 scopus 로고
    • Antifungal studies on some indigenous volatile oils and their combinations
    • Jain S, Jain M. Antifungal studies on some indigenous volatile oils and their combinations. Plant Med. 1972;22(2):136-9.
    • (1972) Plant Med , vol.22 , Issue.2 , pp. 136-139
    • Jain, S.1    Jain, M.2
  • 7
    • 0001712117 scopus 로고
    • Antifungal action of some essential oils against animal pathogens
    • Dikshit A, Husain A. Antifungal action of some essential oils against animal pathogens. Fitoterapia. 1984; 55:171-76.
    • (1984) Fitoterapia , vol.55 , pp. 171-176
    • Dikshit, A.1    Husain, A.2
  • 8
    • 0344192036 scopus 로고
    • Confirmation of structure of the flavonol glucoside tambuletin
    • Nair A, Nair GA, Joshua C. Confirmation of structure of the flavonol glucoside tambuletin. Phytochemistry. 1982;21(2):483-5.
    • (1982) Phytochemistry , vol.21 , Issue.2 , pp. 483-485
    • Nair, A.1    Nair, G.A.2    Joshua, C.3
  • 9
    • 0345552113 scopus 로고    scopus 로고
    • Inhibition of keratinocyte growth by different Nepalese Zanthoxylum species
    • Kumar S, Müller K. Inhibition of keratinocyte growth by different Nepalese Zanthoxylum species. Phytother Res. 1999;13(3):214-7.
    • (1999) Phytother Res , vol.13 , Issue.3 , pp. 214-217
    • Kumar, S.1    Müller, K.2
  • 10
    • 0034988470 scopus 로고    scopus 로고
    • Astaq Mondal khan G: antimicrobial activity and cytotoxicity of Zanthoxylum budrunga
    • Islam A, Sayeed A, Bhuiyan M, Mosaddik M, Islam M. Astaq Mondal khan G: antimicrobial activity and cytotoxicity of Zanthoxylum budrunga. Fitoterapia. 2001;72(4):428-30.
    • (2001) Fitoterapia , vol.72 , Issue.4 , pp. 428-430
    • Islam, A.1    Sayeed, A.2    Bhuiyan, M.3    Mosaddik, M.4    Islam, M.5
  • 11
    • 0038639422 scopus 로고    scopus 로고
    • Screening of traditionally used south African plants for antifungal activity against Candida albicans
    • Motsei M, Lindsey K, Van Staden J, Jäger A. Screening of traditionally used south African plants for antifungal activity against Candida albicans. J Ethnopharmacol. 2003;86(2):235-41.
    • (2003) J Ethnopharmacol , vol.86 , Issue.2 , pp. 235-241
    • Motsei, M.1    Lindsey, K.2    Staden, J.3    Jäger, A.4
  • 12
    • 0004873529 scopus 로고
    • Occurrence of rutaecarpine in Zanthoxylum budrunga
    • Banerjee H, Pal S, Adityachaudhury N. Occurrence of rutaecarpine in Zanthoxylum budrunga. Plant Med. 1989;55:4.
    • (1989) Plant Med , vol.55 , pp. 4
    • Banerjee, H.1    Pal, S.2    Adityachaudhury, N.3
  • 15
    • 77955698031 scopus 로고    scopus 로고
    • Evaluation of crude saponins extract from leaves of Sesbania sesban (L.) Merr. For topical anti-inflammatory activity
    • Dande PR, Talekar VS, Chakraborthy G. Evaluation of crude saponins extract from leaves of Sesbania sesban (L.) Merr. For topical anti-inflammatory activity. Int J Res Pharm Sci. 2010;1(Suppl 3):296-9.
    • (2010) Int J Res Pharm Sci , vol.1 , pp. 296-299
    • Dande, P.R.1    Talekar, V.S.2    Chakraborthy, G.3
  • 16
    • 0023874109 scopus 로고
    • Comparisons of two in vitro cytotoxicity assays-the neutral red (NR) and tetrazolium MTT tests
    • Borenfreund E, Babich H, Martin-Alguacil N. Comparisons of two in vitro cytotoxicity assays-the neutral red (NR) and tetrazolium MTT tests. Toxicol in Vitro. 1988;2(1):1-6.
    • (1988) Toxicol in Vitro , vol.2 , Issue.1 , pp. 1-6
    • Borenfreund, E.1    Babich, H.2    Martin-Alguacil, N.3
  • 17
    • 84902895009 scopus 로고    scopus 로고
    • Cytotoxic effects of Mangifera indica L. kernel extract on human breast cancer (MCF-7 and MDA-MB-231 cell lines) and bioactive constituents in the crude extract
    • Abdullah A-SH, Mohammed AS, Abdullah R, Mirghani MES, Al-Qubaisi M. Cytotoxic effects of Mangifera indica L. kernel extract on human breast cancer (MCF-7 and MDA-MB-231 cell lines) and bioactive constituents in the crude extract. BMC Compl Alter Med. 2014;14(1):199.
    • (2014) BMC Compl Alter Med , vol.14 , Issue.1 , pp. 199
    • Abdullah, A.-S.1    Mohammed, A.S.2    Abdullah, R.3    Mirghani, M.E.S.4    Al-Qubaisi, M.5
  • 18
    • 0021990499 scopus 로고
    • Toxicity determined in vitr o by morphological alterations and neutral red absorption
    • Borenfreund E, Puerner JA. Toxicity determined in vitr o by morphological alterations and neutral red absorption. Toxicol Lett. 1985;24(2):119-24.
    • (1985) Toxicol Lett , vol.24 , Issue.2 , pp. 119-124
    • Borenfreund, E.1    Puerner, J.A.2
  • 19
    • 84877041756 scopus 로고    scopus 로고
    • Ethanolic extract of the goldenseal, Hydrastis canadensis, has demonstrable chemopreventive effects on HeLa cells in vitro: drug-DNA interaction with calf thymus DNA as target
    • Saha SK, Sikdar S, Mukherjee A, Bhadra K, Boujedaini N, Khuda-Bukhsh AR. Ethanolic extract of the goldenseal, Hydrastis canadensis, has demonstrable chemopreventive effects on HeLa cells in vitro: drug-DNA interaction with calf thymus DNA as target. Environ Toxicol Pharmacol. 2013;36(1):202-14.
    • (2013) Environ Toxicol Pharmacol , vol.36 , Issue.1 , pp. 202-214
    • Saha, S.K.1    Sikdar, S.2    Mukherjee, A.3    Bhadra, K.4    Boujedaini, N.5    Khuda-Bukhsh, A.R.6
  • 20
    • 0029927013 scopus 로고    scopus 로고
    • Alternative and complementary cancer therapies
    • Cassileth BR, Chapman CC. Alternative and complementary cancer therapies. Cancer. 1996;77(6):1026-34.
    • (1996) Cancer , vol.77 , Issue.6 , pp. 1026-1034
    • Cassileth, B.R.1    Chapman, C.C.2
  • 21
    • 84876488890 scopus 로고    scopus 로고
    • Zanthoxylum usambarense (Engl.) Kokwaro (Rutaceae) extracts inhibit the growth of the breast cancer cell lines MDA-MB-231 and MCF-7, but not the brain tumour cell line U251 in vitro
    • Özkan M, Mutiso PB, Nahar L, Liu P, Brown S, Wang W, Sarker SD. Zanthoxylum usambarense (Engl.) Kokwaro (Rutaceae) extracts inhibit the growth of the breast cancer cell lines MDA-MB-231 and MCF-7, but not the brain tumour cell line U251 in vitro. Phytother Res. 2013;27(5):787-90.
    • (2013) Phytother Res , vol.27 , Issue.5 , pp. 787-790
    • Özkan, M.1    Mutiso, P.B.2    Nahar, L.3    Liu, P.4    Brown, S.5    Wang, W.6    Sarker, S.D.7
  • 22
    • 67650122861 scopus 로고    scopus 로고
    • Secondary metabolites and cytotoxic activities from the stem bark of Zanthoxylum nitidum
    • ChengHui Y, MingJen C, ShiowJu L, ChengWei Y, HsunShuo C, IhSheng C. Secondary metabolites and cytotoxic activities from the stem bark of Zanthoxylum nitidum. Chem Biodivers. 2009;6(6):846-57.
    • (2009) Chem Biodivers , vol.6 , Issue.6 , pp. 846-857
    • ChengHui, Y.1    MingJen, C.2    ShiowJu, L.3    ChengWei, Y.4    HsunShuo, C.5    IhSheng, C.6
  • 23
    • 79956204057 scopus 로고    scopus 로고
    • Optimization of the tetrazolium dye (MTT) colorimetric assay for cellular growth and viability
    • edn. New York: Springer.
    • Sylvester PW. Optimization of the tetrazolium dye (MTT) colorimetric assay for cellular growth and viability. In: Drug Design and Discovery. edn. New York: Springer. 2011;157-68.
    • (2011) Drug Design and Discovery , pp. 157-168
    • Sylvester, P.W.1
  • 24
    • 2942627418 scopus 로고    scopus 로고
    • Cytotoxic activities of Coriolus versicolor (Yunzhi) extract on human leukemia and lymphoma cells by induction of apoptosis
    • Lau C, Ho C, Kim C, Leung K, Fung K, Tse T, Chan H, Chow M. Cytotoxic activities of Coriolus versicolor (Yunzhi) extract on human leukemia and lymphoma cells by induction of apoptosis. Life Sci. 2004;75(7):797-08.
    • (2004) Life Sci , vol.75 , Issue.7 , pp. 797-808
    • Lau, C.1    Ho, C.2    Kim, C.3    Leung, K.4    Fung, K.5    Tse, T.6    Chan, H.7    Chow, M.8
  • 25
    • 77956655047 scopus 로고    scopus 로고
    • Chemical study and medical application of saponins as anti-cancer agents
    • Man S, Gao W, Zhang Y, Huang L, Liu C. Chemical study and medical application of saponins as anti-cancer agents. Fitoterapia. 2010;81(7):703-14.
    • (2010) Fitoterapia , vol.81 , Issue.7 , pp. 703-714
    • Man, S.1    Gao, W.2    Zhang, Y.3    Huang, L.4    Liu, C.5
  • 26
    • 84860526570 scopus 로고    scopus 로고
    • Chemistry and pharmacology of saponins: special focus on cytotoxic properties
    • Thakur M, Melzig MF, Fuchs H, Weng A. Chemistry and pharmacology of saponins: special focus on cytotoxic properties. Botanics Targets Therapy. 2011;1:19-29.
    • (2011) Botanics Targets Therapy , vol.1 , pp. 19-29
    • Thakur, M.1    Melzig, M.F.2    Fuchs, H.3    Weng, A.4
  • 28
    • 80053348989 scopus 로고    scopus 로고
    • Apoptosis in cancer: from pathogenesis to treatment
    • Wong R. Apoptosis in cancer: from pathogenesis to treatment. J Exp Clin Cancer Res. 2011;30(1):87.
    • (2011) J Exp Clin Cancer Res , vol.30 , Issue.1 , pp. 87
    • Wong, R.1
  • 29
    • 84885596896 scopus 로고    scopus 로고
    • The antitumor effects of triterpenoid saponins from the anemone flaccida and the underlying mechanism
    • Han LT, Fang Y, Li MM, Yang HB, Huang F. The antitumor effects of triterpenoid saponins from the anemone flaccida and the underlying mechanism. Evidence-Based Compl Alter Med. 2013;2013. http://dx.doi.org/10.1155/2013/517931.
    • (2013) Evidence-Based Compl Alter Med , vol.2013
    • Han, L.T.1    Fang, Y.2    Li, M.M.3    Yang, H.B.4    Huang, F.5
  • 30
    • 84978680278 scopus 로고    scopus 로고
    • In vitro antioxidant and cytotoxic activity of Zanthonitrile isolated from Zanthoxylum alatum
    • Karmakar I, Haldar S, Chakraborty M, Dewanjee S, Haldar PK. In vitro antioxidant and cytotoxic activity of Zanthonitrile isolated from Zanthoxylum alatum. J Appl Pharm Sci. 2016;6(06):119-22.
    • (2016) J Appl Pharm Sci , vol.6 , Issue.6 , pp. 119-122
    • Karmakar, I.1    Haldar, S.2    Chakraborty, M.3    Dewanjee, S.4    Haldar, P.K.5
  • 31
    • 84893871980 scopus 로고    scopus 로고
    • Bioactive Lignans from Zanthoxylum alatum Roxb. Stem bark with cytotoxic potential
    • Mukhija M, Dhar KL, Kalia AN. Bioactive Lignans from Zanthoxylum alatum Roxb. Stem bark with cytotoxic potential. J Ethnopharmacol. 2014;152(1):106-12.
    • (2014) J Ethnopharmacol , vol.152 , Issue.1 , pp. 106-112
    • Mukhija, M.1    Dhar, K.L.2    Kalia, A.N.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.