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Volumn 83, Issue , 2017, Pages 71-79

Risk of treatment-related mortality in cancer patients treated with ipilimumab: A systematic review and meta-analysis

Author keywords

Ipilimumab; Randomised controlled trials; Treatment related death

Indexed keywords

IPILIMUMAB; PLACEBO; ANTINEOPLASTIC AGENT; MONOCLONAL ANTIBODY;

EID: 85024098202     PISSN: 09598049     EISSN: 18790852     Source Type: Journal    
DOI: 10.1016/j.ejca.2017.06.021     Document Type: Article
Times cited : (16)

References (32)
  • 1
    • 0032522873 scopus 로고    scopus 로고
    • Incidence of adverse drug reactions in hospitalized patients: a meta-analysis of prospective studies
    • Lazarou, J., Pomeranz, B.H., Corey, P.N., Incidence of adverse drug reactions in hospitalized patients: a meta-analysis of prospective studies. JAMA 279:15 (1998), 1200–1205.
    • (1998) JAMA , vol.279 , Issue.15 , pp. 1200-1205
    • Lazarou, J.1    Pomeranz, B.H.2    Corey, P.N.3
  • 2
    • 84879694541 scopus 로고    scopus 로고
    • Incidence and risk of treatment-related mortality in cancer patients treated with the mammalian target of rapamycin inhibitors
    • Choueiri, T.K., Je, Y., Sonpavde, G., et al. Incidence and risk of treatment-related mortality in cancer patients treated with the mammalian target of rapamycin inhibitors. Ann Oncol 24:8 (2013), 2092–2097.
    • (2013) Ann Oncol , vol.24 , Issue.8 , pp. 2092-2097
    • Choueiri, T.K.1    Je, Y.2    Sonpavde, G.3
  • 3
    • 84858848994 scopus 로고    scopus 로고
    • Meta-analysis of randomized controlled trials for the incidence and risk of treatment-related mortality in patients with cancer treated with vascular endothelial growth factor tyrosine kinase inhibitors
    • Schutz, F.A., Je, Y., Richards, C.J., Choueiri, T.K., Meta-analysis of randomized controlled trials for the incidence and risk of treatment-related mortality in patients with cancer treated with vascular endothelial growth factor tyrosine kinase inhibitors. J Clin Oncol 30:8 (2012), 871–877.
    • (2012) J Clin Oncol , vol.30 , Issue.8 , pp. 871-877
    • Schutz, F.A.1    Je, Y.2    Richards, C.J.3    Choueiri, T.K.4
  • 4
    • 79551520348 scopus 로고    scopus 로고
    • Treatment-related mortality with bevacizumab in cancer patients: a meta-analysis
    • Ranpura, V., Hapani, S., Wu, S., Treatment-related mortality with bevacizumab in cancer patients: a meta-analysis. JAMA 305:5 (2011), 487–494.
    • (2011) JAMA , vol.305 , Issue.5 , pp. 487-494
    • Ranpura, V.1    Hapani, S.2    Wu, S.3
  • 5
    • 77954801079 scopus 로고    scopus 로고
    • Improved survival with ipilimumab in patients with metastatic melanoma
    • Hodi, F.S., O'Day, S.J., McDermott, D.F., et al. Improved survival with ipilimumab in patients with metastatic melanoma. N Engl J Med 363:8 (2010), 711–723.
    • (2010) N Engl J Med , vol.363 , Issue.8 , pp. 711-723
    • Hodi, F.S.1    O'Day, S.J.2    McDermott, D.F.3
  • 6
    • 84929192743 scopus 로고    scopus 로고
    • Ipilimumab-dependent cell-mediated cytotoxicity of regulatory T cells ex vivo by nonclassical monocytes in melanoma patients
    • Romano, E., Kusio-Kobialka, M., Foukas, P.G., et al. Ipilimumab-dependent cell-mediated cytotoxicity of regulatory T cells ex vivo by nonclassical monocytes in melanoma patients. Proc Natl Acad Sci U S A 112:19 (2015), 6140–6145.
    • (2015) Proc Natl Acad Sci U S A , vol.112 , Issue.19 , pp. 6140-6145
    • Romano, E.1    Kusio-Kobialka, M.2    Foukas, P.G.3
  • 7
    • 79959772576 scopus 로고    scopus 로고
    • Ipilimumab plus dacarbazine for previously untreated metastatic melanoma
    • Robert, C., Thomas, L., Bondarenko, I., et al. Ipilimumab plus dacarbazine for previously untreated metastatic melanoma. N Engl J Med 364:26 (2011), 2517–2526.
    • (2011) N Engl J Med , vol.364 , Issue.26 , pp. 2517-2526
    • Robert, C.1    Thomas, L.2    Bondarenko, I.3
  • 8
    • 84971620553 scopus 로고    scopus 로고
    • Nivolumab alone and nivolumab plus ipilimumab in recurrent small-cell lung cancer (CheckMate 032): a multicentre, open-label, phase 1/2 trial
    • Antonia, S.J., Lopez-Martin, J.A., Bendell, J., et al. Nivolumab alone and nivolumab plus ipilimumab in recurrent small-cell lung cancer (CheckMate 032): a multicentre, open-label, phase 1/2 trial. Lancet Oncol 17:7 (2016), 883–895.
    • (2016) Lancet Oncol , vol.17 , Issue.7 , pp. 883-895
    • Antonia, S.J.1    Lopez-Martin, J.A.2    Bendell, J.3
  • 9
    • 85007425840 scopus 로고    scopus 로고
    • Nivolumab plus ipilimumab as first-line treatment for advanced non-small-cell lung cancer (CheckMate 012): results of an open-label, phase 1, multicohort study
    • Hellmann, M.D., Rizvi, N.A., Goldman, J.W., et al. Nivolumab plus ipilimumab as first-line treatment for advanced non-small-cell lung cancer (CheckMate 012): results of an open-label, phase 1, multicohort study. Lancet Oncol 18:1 (2017), 31–41.
    • (2017) Lancet Oncol , vol.18 , Issue.1 , pp. 31-41
    • Hellmann, M.D.1    Rizvi, N.A.2    Goldman, J.W.3
  • 10
    • 84864052441 scopus 로고    scopus 로고
    • Management of immune-related adverse events and kinetics of response with ipilimumab
    • Weber, J.S., Kahler, K.C., Hauschild, A., Management of immune-related adverse events and kinetics of response with ipilimumab. J Clin Oncol 30:21 (2012), 2691–2697.
    • (2012) J Clin Oncol , vol.30 , Issue.21 , pp. 2691-2697
    • Weber, J.S.1    Kahler, K.C.2    Hauschild, A.3
  • 11
    • 84944261579 scopus 로고    scopus 로고
    • Immune-related adverse events, need for systemic immunosuppression, and effects on survival and time to treatment failure in patients with melanoma treated with ipilimumab at memorial Sloan Kettering Cancer Center
    • Horvat, T.Z., Adel, N.G., Dang, T.O., et al. Immune-related adverse events, need for systemic immunosuppression, and effects on survival and time to treatment failure in patients with melanoma treated with ipilimumab at memorial Sloan Kettering Cancer Center. J Clin Oncol 33:28 (2015), 3193–3198.
    • (2015) J Clin Oncol , vol.33 , Issue.28 , pp. 3193-3198
    • Horvat, T.Z.1    Adel, N.G.2    Dang, T.O.3
  • 12
    • 85009783306 scopus 로고    scopus 로고
    • Randomized, double-blind, phase III trial of ipilimumab versus placebo in asymptomatic or minimally symptomatic patients with metastatic chemotherapy-Naive castration-resistant prostate cancer
    • Beer, T.M., Kwon, E.D., Drake, C.G., et al. Randomized, double-blind, phase III trial of ipilimumab versus placebo in asymptomatic or minimally symptomatic patients with metastatic chemotherapy-Naive castration-resistant prostate cancer. J Clin Oncol 35:1 (2017), 40–47.
    • (2017) J Clin Oncol , vol.35 , Issue.1 , pp. 40-47
    • Beer, T.M.1    Kwon, E.D.2    Drake, C.G.3
  • 13
    • 85024098752 scopus 로고    scopus 로고
    • Food and Drug Administration Amendments Act (FDAAA) of 2007. US Public Law 110-85 section 801. [Accessd 13 November ].
    • US Food and Drug Administration. Food and Drug Administration Amendments Act (FDAAA) of 2007. US Public Law 110-85 section 801. www.gpo.gov/fdsys/pkg/PLAW-110publ85/pdf/PLAW-110publ85.pdf. [Accessd 13 November 2016].
    • (2016)
  • 14
    • 0000694159 scopus 로고
    • Transformations related to the angular and the square root
    • Freeman, M.F.T.J., Transformations related to the angular and the square root. Ann Math Stats 21 (1950), 607–611.
    • (1950) Ann Math Stats , vol.21 , pp. 607-611
    • Freeman, M.F.T.J.1
  • 15
    • 33846260745 scopus 로고    scopus 로고
    • Much ado about nothing: a comparison of the performance of meta-analytical methods with rare events
    • Bradburn, M.J., Deeks, J.J., Berlin, J.A., Russell Localio, A., Much ado about nothing: a comparison of the performance of meta-analytical methods with rare events. Stat Med 26:1 (2007), 53–77.
    • (2007) Stat Med , vol.26 , Issue.1 , pp. 53-77
    • Bradburn, M.J.1    Deeks, J.J.2    Berlin, J.A.3    Russell Localio, A.4
  • 16
    • 84994874924 scopus 로고    scopus 로고
    • Prolonged survival in stage III melanoma with ipilimumab adjuvant therapy
    • Eggermont, A.M., Chiarion-Sileni, V., Grob, J.J., et al. Prolonged survival in stage III melanoma with ipilimumab adjuvant therapy. N Engl J Med 375:19 (2016), 1845–1855.
    • (2016) N Engl J Med , vol.375 , Issue.19 , pp. 1845-1855
    • Eggermont, A.M.1    Chiarion-Sileni, V.2    Grob, J.J.3
  • 17
    • 84863911486 scopus 로고    scopus 로고
    • Ipilimumab in combination with paclitaxel and carboplatin as first-line treatment in stage IIIB/IV non-small-cell lung cancer: results from a randomized, double-blind, multicenter phase II study
    • Lynch, T.J., Bondarenko, I., Luft, A., et al. Ipilimumab in combination with paclitaxel and carboplatin as first-line treatment in stage IIIB/IV non-small-cell lung cancer: results from a randomized, double-blind, multicenter phase II study. J Clin Oncol 30:17 (2012), 2046–2054.
    • (2012) J Clin Oncol , vol.30 , Issue.17 , pp. 2046-2054
    • Lynch, T.J.1    Bondarenko, I.2    Luft, A.3
  • 18
    • 84901641673 scopus 로고    scopus 로고
    • Ipilimumab versus placebo after radiotherapy in patients with metastatic castration-resistant prostate cancer that had progressed after docetaxel chemotherapy (CA184-043): a multicentre, randomised, double-blind, phase 3 trial
    • Kwon, E.D., Drake, C.G., Scher, H.I., et al. Ipilimumab versus placebo after radiotherapy in patients with metastatic castration-resistant prostate cancer that had progressed after docetaxel chemotherapy (CA184-043): a multicentre, randomised, double-blind, phase 3 trial. Lancet Oncol 15:7 (2014), 700–712.
    • (2014) Lancet Oncol , vol.15 , Issue.7 , pp. 700-712
    • Kwon, E.D.1    Drake, C.G.2    Scher, H.I.3
  • 19
    • 84936147067 scopus 로고    scopus 로고
    • Combined nivolumab and ipilimumab or monotherapy in untreated melanoma
    • Larkin, J., Chiarion-Sileni, V., Gonzalez, R., et al. Combined nivolumab and ipilimumab or monotherapy in untreated melanoma. N Engl J Med 373:1 (2015), 23–34.
    • (2015) N Engl J Med , vol.373 , Issue.1 , pp. 23-34
    • Larkin, J.1    Chiarion-Sileni, V.2    Gonzalez, R.3
  • 20
    • 84929481481 scopus 로고    scopus 로고
    • Pembrolizumab versus ipilimumab in advanced melanoma
    • Robert, C., Schachter, J., Long, G.V., et al. Pembrolizumab versus ipilimumab in advanced melanoma. N Engl J Med 372:26 (2015), 2521–2532.
    • (2015) N Engl J Med , vol.372 , Issue.26 , pp. 2521-2532
    • Robert, C.1    Schachter, J.2    Long, G.V.3
  • 21
    • 84871532643 scopus 로고    scopus 로고
    • Ipilimumab in combination with paclitaxel and carboplatin as first-line therapy in extensive-disease-small-cell lung cancer: results from a randomized, double-blind, multicenter phase 2 trial
    • Reck, M., Bondarenko, I., Luft, A., et al. Ipilimumab in combination with paclitaxel and carboplatin as first-line therapy in extensive-disease-small-cell lung cancer: results from a randomized, double-blind, multicenter phase 2 trial. Ann Oncol 24:1 (2013), 75–83.
    • (2013) Ann Oncol , vol.24 , Issue.1 , pp. 75-83
    • Reck, M.1    Bondarenko, I.2    Luft, A.3
  • 22
    • 84993940004 scopus 로고    scopus 로고
    • Phase III randomized trial of ipilimumab plus etoposide and platinum versus placebo plus etoposide and platinum in extensive-stage small-cell lung cancer
    • Reck, M., Luft, A., Szczesna, A., et al. Phase III randomized trial of ipilimumab plus etoposide and platinum versus placebo plus etoposide and platinum in extensive-stage small-cell lung cancer. J Clin Oncol 34:31 (2016), 3740–3748.
    • (2016) J Clin Oncol , vol.34 , Issue.31 , pp. 3740-3748
    • Reck, M.1    Luft, A.2    Szczesna, A.3
  • 23
    • 85024132681 scopus 로고    scopus 로고
    • An Efficacy Study in Gastric and Gastroesophageal Junction Cancer Comparing Ipilimumab Versus Standard of Care Immediately Following First Line Chemotherapy. [Accessed 16 November ].
    • Bristol-Myers Squibb. An Efficacy Study in Gastric and Gastroesophageal Junction Cancer Comparing Ipilimumab Versus Standard of Care Immediately Following First Line Chemotherapy. https://clinicaltrials.gov/ct2/show/NCT01585987?term=NCT01585987. [Accessed 16 November 2016].
    • (2016)
  • 24
    • 85024090682 scopus 로고    scopus 로고
    • Phase 3 Trial in Squamous Non Small Cell Lung Cancer Subjects Comparing Ipilimumab Versus Placebo in Addition to Paclitaxel and Carboplatin. [Accessed 16 November ].
    • Bristol-Myers Squibb. Phase 3 Trial in Squamous Non Small Cell Lung Cancer Subjects Comparing Ipilimumab Versus Placebo in Addition to Paclitaxel and Carboplatin. https://clinicaltrials.gov/ct2/show/NCT01285609?term=NCT01285609. [Accessed 16 November 2016].
    • (2016)
  • 25
    • 84945472104 scopus 로고    scopus 로고
    • Review of immune-related adverse events in prostate cancer patients treated with ipilimumab: MD Anderson experience
    • Gao, J., He, Q., Subudhi, S., et al. Review of immune-related adverse events in prostate cancer patients treated with ipilimumab: MD Anderson experience. Oncogene 34:43 (2015), 5411–5417.
    • (2015) Oncogene , vol.34 , Issue.43 , pp. 5411-5417
    • Gao, J.1    He, Q.2    Subudhi, S.3
  • 26
    • 84876678621 scopus 로고    scopus 로고
    • Patterns of onset and resolution of immune-related adverse events of special interest with ipilimumab: detailed safety analysis from a phase 3 trial in patients with advanced melanoma
    • Weber, J.S., Dummer, R., de Pril, V., Lebbe, C., Hodi, F.S., Patterns of onset and resolution of immune-related adverse events of special interest with ipilimumab: detailed safety analysis from a phase 3 trial in patients with advanced melanoma. Cancer 119:9 (2013), 1675–1682.
    • (2013) Cancer , vol.119 , Issue.9 , pp. 1675-1682
    • Weber, J.S.1    Dummer, R.2    de Pril, V.3    Lebbe, C.4    Hodi, F.S.5
  • 27
    • 56649123212 scopus 로고    scopus 로고
    • Risk of venous thromboembolism with the angiogenesis inhibitor bevacizumab in cancer patients: a meta-analysis
    • Nalluri, S.R., Chu, D., Keresztes, R., Zhu, X., Wu, S., Risk of venous thromboembolism with the angiogenesis inhibitor bevacizumab in cancer patients: a meta-analysis. JAMA 300:19 (2008), 2277–2285.
    • (2008) JAMA , vol.300 , Issue.19 , pp. 2277-2285
    • Nalluri, S.R.1    Chu, D.2    Keresztes, R.3    Zhu, X.4    Wu, S.5
  • 28
    • 65349156896 scopus 로고    scopus 로고
    • Risk of venous thromboembolism with bevacizumab in cancer patients
    • author reply 1435–1436
    • Minor, D.R., Risk of venous thromboembolism with bevacizumab in cancer patients. JAMA, 301(14), 2009, 1434 author reply 1435–1436.
    • (2009) JAMA , vol.301 , Issue.14 , pp. 1434
    • Minor, D.R.1
  • 29
    • 70349393610 scopus 로고    scopus 로고
    • Risk of bleeding with vascular endothelial growth factor receptor tyrosine-kinase inhibitors sunitinib and sorafenib: a systematic review and meta-analysis of clinical trials
    • Je, Y., Schutz, F.A., Choueiri, T.K., Risk of bleeding with vascular endothelial growth factor receptor tyrosine-kinase inhibitors sunitinib and sorafenib: a systematic review and meta-analysis of clinical trials. Lancet Oncol 10:10 (2009), 967–974.
    • (2009) Lancet Oncol , vol.10 , Issue.10 , pp. 967-974
    • Je, Y.1    Schutz, F.A.2    Choueiri, T.K.3
  • 30
    • 75249093377 scopus 로고    scopus 로고
    • Risk of bleeding not increased by sorafenib or sunitinib
    • author reply 113
    • Minor, D.R., Risk of bleeding not increased by sorafenib or sunitinib. Lancet Oncol 11:2 (2010), 112–113 author reply 113.
    • (2010) Lancet Oncol , vol.11 , Issue.2 , pp. 112-113
    • Minor, D.R.1
  • 31
    • 77952310126 scopus 로고    scopus 로고
    • Risk of arterial thromboembolic events with sunitinib and sorafenib: a systematic review and meta-analysis of clinical trials
    • Choueiri, T.K., Schutz, F.A., Je, Y., Rosenberg, J.E., Bellmunt, J., Risk of arterial thromboembolic events with sunitinib and sorafenib: a systematic review and meta-analysis of clinical trials. J Clin Oncol 28:13 (2010), 2280–2285.
    • (2010) J Clin Oncol , vol.28 , Issue.13 , pp. 2280-2285
    • Choueiri, T.K.1    Schutz, F.A.2    Je, Y.3    Rosenberg, J.E.4    Bellmunt, J.5
  • 32
    • 78049501837 scopus 로고    scopus 로고
    • Risk of arterial thrombosis not increased by sorafenib or sunitinib
    • author reply e620
    • Minor, D.R., Risk of arterial thrombosis not increased by sorafenib or sunitinib. J Clin Oncol, 28(30), 2010, e619 author reply e620.
    • (2010) J Clin Oncol , vol.28 , Issue.30 , pp. e619
    • Minor, D.R.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.