Anti-Factor B and Anti-C3b autoantibodies in C3 glomerulopathy and ig-associated membranoproliferative GN

Journal of the American Society of Nephrology

Volumn 28, Issue 5, 2017, Pages 1603-1613

  Chiara Marinozzi, Maria ^a,b   Roumenina, Lubka T ^a,c,d   Chauvet, Sophie ^a   Hertig, Alexandre ^e   Bertrand, Dominique ^f   Olagne, JéRome ^g   Frimat, Marie ^h   Ulinski, Tim ⁱ   Deschênes, Georges ^j   Burtey, Stephane ^k   Delahousse, Michel ^l   Moulin, Bruno ^g   Legendre, Christophe ^m   Frémeaux Bacchi, Véronique ^a,b   Le Quintrec, Moglie ^a,b,n  

^a INSERM   (France)

^b HÔPITAL EUROPÉEN GEORGES POMPIDOU   (France)

^c UNIVERSITÉ PARIS DESCARTES   (France)

^d SORBONNE UNIVERSITÉ   (France)

^e HÔPITAL TENON   (France)

^f Dept de Médecine Interne Ctr Hosp Univ Rouen Boisguillaume   (France)

^g Service de Néphrologie et de Transplantation Rénale   (France)

^h Service de Néphrologie et de Transplantation Rénale   (France)

ⁱ ARMAND TROUSSEAU HOSPITAL   (France)

^j HÔPITAL ROBERT DEBRÉ   (France)

^k AIX MARSEILLE UNIVERSITY   (France)

^l FOCH HOSPITAL   (France)

^m HÔPITAL NECKER ENFANTS MALADES   (France)

ⁿ H Ôpital Lapeyronnie   (France)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ALTERNATIVE COMPLEMENT PATHWAY C3 C5 CONVERTASE ANTIBODY; AUTOANTIBODY; CLASSICAL COMPLEMENT PATHWAY C3 C5 CONVERTASE; COMPLEMENT COMPONENT C3; COMPLEMENT COMPONENT C3B; COMPLEMENT COMPONENT C3B ANTIBODY; COMPLEMENT COMPONENT C5; CREATININE; IMMUNOGLOBULIN G; UNCLASSIFIED DRUG; ALTERNATIVE COMPLEMENT PATHWAY C3 C5 CONVERTASE;

ADOLESCENT; ADULT; ANTIGEN BINDING; CELL SURFACE; CHILD; COHORT ANALYSIS; COMPLEMENT DEPOSITION; CONFERENCE PAPER; CONTROLLED STUDY; END STAGE RENAL DISEASE; ENDOTHELIUM CELL; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; EPITOPE MAPPING; FEMALE; FOLLOW UP; GLOMERULOPATHY; HUMAN; IN VITRO STUDY; LIQUID; MAJOR CLINICAL STUDY; MALE; MEMBRANOPROLIFERATIVE GLOMERULONEPHRITIS; NEPHROTIC SYNDROME; PRIORITY JOURNAL; RETROSPECTIVE STUDY; TREATMENT OUTCOME; IMMUNOLOGY; MIDDLE AGED; YOUNG ADULT;

ADOLESCENT; ADULT; AUTOANTIBODIES; CHILD; COMPLEMENT C3B; COMPLEMENT FACTOR B; FEMALE; GLOMERULONEPHRITIS, MEMBRANOPROLIFERATIVE; HUMANS; IMMUNOGLOBULIN G; MALE; MIDDLE AGED; RETROSPECTIVE STUDIES; YOUNG ADULT;

EID: 85021849860     PISSN: 10466673     EISSN: 15333450     Source Type: Journal    
DOI: 10.1681/ASN.2016030343     Document Type: Conference Paper

References (24)

1. Merle NS, Noe R, Halbwachs-Mecarelli L, Fremeaux-Bacchi V, Roumenina LT: Complement system part II: Role in immunity. Front Immunol 6: 257, 2015
2. MerleNS, Church SE, Fremeaux-Bacchi V, Roumenina LT: Complement system part I - molecular mechanisms of activation and regulation. Front Immunol 6: 262, 2015
3. Zipfel PF, Skerka C, Chen Q, Wiech T, Goodship T, Johnson S, Fremeaux-Bacchi V, Nester C, de Córdoba SR, Noris M, Pickering M, Smith R: The role of complement in C3 glomerulopathy. Mol Immunol 67: 21-30, 2015
4. Servais A, Noël LH, Roumenina LT, Le Quintrec M, Ngo S, Dragon-DureyMA, Macher MA, Zuber J, Karras A, Provot F, Moulin B, Grünfeld JP, Niaudet P, Lesavre P, Frémeaux-Bacchi V: Acquired and genetic complement abnormalities play a critical role in dense deposit disease and other C3 glomerulopathies. Kidney Int 82: 454-464, 2012
5. Cook HT, Pickering MC: Histopathology of MPGN and C3 glomerulopathies. Nat Rev Nephrol 11: 14-22, 2015
6. Pickering MC, D'Agati VD, Nester CM, Smith RJ, Haas M, Appel GB, Alpers CE, Bajema IM, Bedrosian C, Braun M, Doyle M, Fakhouri F, Fervenza FC, Fogo AB, Frémeaux-Bacchi V, Gale DP, Goicoechea de Jorge E, Griffin G, Harris CL, Holers VM, Johnson S, Lavin PJ, Medjeral-Thomas N, PaulMorgan B, Nast CC, Noel LH, Peters DK, Rodríguez de Córdoba S, Servais A, Sethi S, Song WC, Tamburini P, Thurman JM, Zavros M, Cook HT: C3 glomerulopathy: Consensus report. Kidney Int 84: 1079-1089, 2013
7. Strobel S, Zimmering M, Papp K, Prechl J, Józsi M: Anti-factor B autoantibody in dense deposit disease. Mol Immunol 47: 1476-1483, 2010
8. Chen Q, Müller D, Rudolph B, Hartmann A, Kuwertz-Bröking E, Wu K, Kirschfink M, Skerka C, Zipfel PF: Combined C3b and factor B autoantibodies and MPGN type II. N Engl J Med 365: 2340-2342, 2011
9. Sethi S, Fervenza FC: Membranoproliferative glomerulonephritis-a new look at an old entity. N Engl JMed 366: 1119-1131, 2012
10. Servais A, Noël LH, Dragon-Durey MA, Gübler MC, Rémy P, Buob D, Cordonnier C, Makdassi R, JaberW, Boulanger E, Lesavre P, Frémeaux-Bacchi V: Heterogeneous pattern of renal disease associated with homozygous factor H deficiency. Hum Pathol 42: 1305-1311, 2011
11. Alfandary H, Davidovits M: Novel factor H mutation associated with familial membranoproliferative glomerulonephritis type I. Pediatr Nephrol 30: 2129-2134, 2015
12. Iatropoulos P, Noris M, Mele C, Piras R, Valoti E, Bresin E, Curreri M, Mondo E, Zito A, Gamba S, Bettoni S, Murer L, Fremeaux-Bacchi V, Vivarelli M, Emma F, Daina E, Remuzzi G: Complement gene variants determine the risk of immunoglobulin-associated MPGN and C3 glomerulopathy and predict long-term renal outcome. Mol Immunol 71: 131-142, 2016
13. Couser WG: Basic and translational concepts of immune-mediated glomerular diseases. J Am Soc Nephrol 23: 381-399, 2012
14. Pickering MC, Cook HT: Translational mini-review series on complement factor H: Renal diseases associated with complement factor H: Novel insights from humans and animals. Clin Exp Immunol 151: 210-230, 2008
15. Nasr SH, FidlerME, Valeri AM, Cornell LD, Sethi S, Zoller A, StokesMB, Markowitz GS, D'Agati VD: Postinfectious glomerulonephritis in the elderly. J Am Soc Nephrol 22: 187-195, 2011
16. Rabasco C, Cavero T, Román E, Rojas-Rivera J, Olea T, Espinosa M, Cabello V, Fernández-Juarez G, González F, Ávila A, Baltar JM, DíazM, Alegre R, Elías S, Antón M, Frutos MA, Pobes A, Blasco M, Martín F, Bernis C, Macías M, Barroso S, de Lorenzo A, Ariceta G, López-Mendoza M, Rivas B, López-Revuelta K, Campistol JM, Mendizábal S, de Córdoba SR, Praga M; Spanish Group for the Study of Glomerular Diseases (GLOSEN): Effectiveness of mycophenolate mofetil in C3 glomerulonephritis. Kidney Int 88: 1153-1160, 2015
17. Le Quintrec M, Lionet A, Kandel C, Bourdon F, Gnemmi V, Colombat M, Goujon JM, Frémeaux-Bacchi V, Fakhouri F: Eculizumab for treatment of rapidly progressive C3 glomerulopathy. Am J Kidney Dis 65: 484-489, 2015
18. Bajic G, Degn SE, Thiel S, Andersen GR: Complement activation, regulation, andmolecular basis for complement-related diseases. EMBO J 34: 2735-2757, 2015
19. Chauvet S, Roumenina LT, Bruneau S, Marinozzi MC, Rybkine T, Schramm EC, Java A, Atkinson JP, Aldigier JC, Bridoux F, Touchard G, Fremeaux-Bacchi V: A familial C3GN secondary to defective C3 regulation by complement receptor 1 and factor H. J Am Soc Nephrol 27: 1665-1677, 2015
20. Schramm EC, Roumenina LT, Rybkine T, Chauvet S, Vieira-Martins P, Hue C, Maga T, Valoti E, Wilson V, Jokiranta S, Smith RJ, Noris M, Goodship T, Atkinson JP, Fremeaux-Bacchi V: Mapping intractions between complement C3 and regulators using mutations in atypical hemolytic uremic syndrome. Blood 125: 2359-2369, 2015
21. Vasilev VV, Noe R, Dragon-Durey MA, Chauvet S, Lazarov VJ, Deliyska BP, Fremeaux-Bacchi V, Dimitrov JD, Roumenina LT: Functional characterization of autoantibodies against complement component C3 in patients with lupus nephritis. J Biol Chem 290: 25343-25355, 2015
22. Birmingham DJ, Bitter JE, Ndukwe EG, Dials S, Gullo TR, Conroy S, Nagaraja HN, Rovin BH, Hebert LA: Relationship of circulating anti-C3b and anti-C1q IgG to lupus nephritis and its flare. Clin J AmSoc Nephrol 11: 47-53, 2016
23. Roumenina LT, Loirat C, Dragon-Durey MA, Halbwachs-Mecarelli L, Sautes-Fridman C, Fremeaux-Bacchi V: Alternative complement pathway assessment in patients with atypical HUS. J Immunol Methods 365: 8-26, 2011
24. Frémeaux-Bacchi V, Weiss L, Brun P, Kazatchkine MD: Selective disappearance of C3NeF IgG autoantibody in the plasma of a patient with membranoproliferative glomerulonephritis following renal transplantation. Nephrol Dial Transplant 9: 811-814, 1994