E-scape: Interactive visualization of single-cell phylogenetics and cancer evolution

Nature Methods

Volumn 14, Issue 6, 2017, Pages 549-550

  Smith, Maia A ^a,b   Nielsen, Cydney B ^a,b   Chan, Fong Chun ^b   McPherson, Andrew ^b   Roth, Andrew ^b   Farahani, Hossein ^b   MacHev, Daniel ^b   Steif, Adi ^b   Shah, Sohrab P ^a,b  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b BRITISH COLUMBIA CANCER AGENCY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CANCER CELL; CELL CLONE; CELL LINEAGE; CELL POPULATION; CLONAL EVOLUTION; HUMAN; LETTER; NONHUMAN; PHYLOGENY; POINT MUTATION; PRIORITY JOURNAL; GENETICS; MOLECULAR EVOLUTION; NEOPLASM; PROCEDURES; SINGLE CELL ANALYSIS; SOFTWARE;

EVOLUTION, MOLECULAR; HUMANS; NEOPLASMS; PHYLOGENY; SINGLE-CELL ANALYSIS; SOFTWARE;

EID: 85021801799     PISSN: 15487091     EISSN: 15487105     Source Type: Journal    
DOI: 10.1038/nmeth.4303     Document Type: Letter

References (6)

1. Ding, L. et al. Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing. Nature 481, 506-510 (2012).
2. Eirew, P. et al. Dynamics of genomic clones in breast cancer patient xenografts at single-cell resolution. Nature 518, 422-426 (2015).
3. Gundem, G. et al. The evolutionary history of lethal metastatic prostate cancer. Nature 520, 353-357 (2015).
4. McPherson, A. et al. Divergent modes of clonal spread and intraperitoneal mixing in high-grade serous ovarian cancer. Nat. Genet. 48, 758-767 (2016).
5. Kridel, R. et al. Histological transformation and progression in follicular lymphoma: A clonal evolution study. PLoS Med. 13, e1002197 (2016).
6. Wang, Y. et al. Clonal evolution in breast cancer revealed by single nucleus genome sequencing. Nature 512, 155-160 (2014).