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Volumn 129, Issue 25, 2017, Pages 3371-3378

Clinical significance of somatic mutation in unexplained blood cytopenia

Author keywords

[No Author keywords available]

Indexed keywords

DNA METHYLTRANSFERASE 3A;

EID: 85021647193     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2017-01-763425     Document Type: Article
Times cited : (385)

References (40)
  • 1
    • 79955034371 scopus 로고    scopus 로고
    • Anemia in elderly patients: An emerging problem for the 21st century
    • Vanasse GJ, Berliner N. Anemia in elderly patients: an emerging problem for the 21st century. Hematology Am Soc Hematol Educ Program. 2010;2010: 271-275.
    • (2010) Hematology Am Soc Hematol Educ Program , vol.2010 , pp. 271-275
    • Vanasse, G.J.1    Berliner, N.2
  • 2
    • 4944261763 scopus 로고    scopus 로고
    • Prevalence of anemia in persons 65 years and older in the United States: Evidence for a high rate of unexplained anemia
    • Guralnik JM, Eisenstaedt RS, Ferrucci L, Klein HG, Woodman RC. Prevalence of anemia in persons 65 years and older in the United States: evidence for a high rate of unexplained anemia. Blood. 2004;104(8): 2263-2268.
    • (2004) Blood , vol.104 , Issue.8 , pp. 2263-2268
    • Guralnik, J.M.1    Eisenstaedt, R.S.2    Ferrucci, L.3    Klein, H.G.4    Woodman, R.C.5
  • 3
    • 78149240232 scopus 로고    scopus 로고
    • Prevalence, incidence and types of mild anemia in the elderly: The “health and anemia” population-based study
    • Tettamanti M, Lucca U, Gandini F, et al. Prevalence, incidence and types of mild anemia in the elderly: the “Health and Anemia” population-based study. Haematologica. 2010;95(11): 1849-1856.
    • (2010) Haematologica , vol.95 , Issue.11 , pp. 1849-1856
    • Tettamanti, M.1    Lucca, U.2    Gandini, F.3
  • 4
    • 34249663842 scopus 로고    scopus 로고
    • Racial variation in the relationship of anemia with mortality and mobility disability among older adults
    • Patel KV, Harris TB, Faulhaber M, et al. Racial variation in the relationship of anemia with mortality and mobility disability among older adults. Blood. 2007;109(11): 4663-4670.
    • (2007) Blood , vol.109 , Issue.11 , pp. 4663-4670
    • Patel, K.V.1    Harris, T.B.2    Faulhaber, M.3
  • 5
    • 58149236988 scopus 로고    scopus 로고
    • Association of mild anemia with hospitalization and mortality in the elderly: The health and anemia population-based study
    • Riva E, Tettamanti M, Mosconi P, et al. Association of mild anemia with hospitalization and mortality in the elderly: the Health and Anemia population-based study. Haematologica. 2009;94(1): 22-28.
    • (2009) Haematologica , vol.94 , Issue.1 , pp. 22-28
    • Riva, E.1    Tettamanti, M.2    Mosconi, P.3
  • 6
    • 33847350296 scopus 로고    scopus 로고
    • Unexplained anaemia in older persons is characterised by low erythropoietin and low levels of pro-inflammatory markers
    • Ferrucci L, Guralnik JM, Bandinelli S, et al. Unexplained anaemia in older persons is characterised by low erythropoietin and low levels of pro-inflammatory markers. Br J Haematol. 2007;136(6): 849-855.
    • (2007) Br J Haematol , vol.136 , Issue.6 , pp. 849-855
    • Ferrucci, L.1    Guralnik, J.M.2    Bandinelli, S.3
  • 8
    • 84891301466 scopus 로고    scopus 로고
    • The genetic basis of myelodysplasia and its clinical relevance
    • Cazzola M, Della Porta MG, Malcovati L. The genetic basis of myelodysplasia and its clinical relevance. Blood. 2013;122(25): 4021-4034.
    • (2013) Blood , vol.122 , Issue.25 , pp. 4021-4034
    • Cazzola, M.1    Della Porta, M.G.2    Malcovati, L.3
  • 9
    • 77956397358 scopus 로고    scopus 로고
    • Incidence and clinical complications of myelodysplastic syndromes among United States medicare beneficiaries
    • Goldberg SL, Chen E, Corral M, et al. Incidence and clinical complications of myelodysplastic syndromes among United States Medicare beneficiaries. J Clin Oncol. 2010;28(17): 2847-2852.
    • (2010) J Clin Oncol , vol.28 , Issue.17 , pp. 2847-2852
    • Goldberg, S.L.1    Chen, E.2    Corral, M.3
  • 10
    • 79959851207 scopus 로고    scopus 로고
    • Incidence of the myelodysplastic syndromes using a novel claims-based algorithm: High number of uncaptured cases by cancer registries
    • Cogle CR, Craig BM, Rollison DE, List AF. Incidence of the myelodysplastic syndromes using a novel claims-based algorithm: high number of uncaptured cases by cancer registries. Blood. 2011;117(26): 7121-7125.
    • (2011) Blood , vol.117 , Issue.26 , pp. 7121-7125
    • Cogle, C.R.1    Craig, B.M.2    Rollison, D.E.3    List, A.F.4
  • 11
    • 84888240132 scopus 로고    scopus 로고
    • Diagnosis and treatment of primary myelodysplastic syndromes in adults: Recommendations from the european leukemianet
    • European Leukemia Net
    • Malcovati L, Hellström-Lindberg E, Bowen D, et al; European Leukemia Net. Diagnosis and treatment of primary myelodysplastic syndromes in adults: recommendations from the European LeukemiaNet. Blood. 2013;122(17): 2943-2964.
    • (2013) Blood , vol.122 , Issue.17 , pp. 2943-2964
    • Malcovati, L.1    Hellström-Lindberg, E.2    Bowen, D.3
  • 12
    • 0036786901 scopus 로고    scopus 로고
    • The world health organization (who) classification of the myeloid neoplasms
    • Vardiman JW, Harris NL, Brunning RD. The World Health Organization (WHO) classification of the myeloid neoplasms. Blood. 2002;100(7): 2292-2302.
    • (2002) Blood , vol.100 , Issue.7 , pp. 2292-2302
    • Vardiman, J.W.1    Harris, N.L.2    Brunning, R.D.3
  • 13
    • 70349256226 scopus 로고    scopus 로고
    • The 2008 revision of the world health organization (who) classification of myeloid neoplasms and acute leukemia: Rationale and important changes
    • Vardiman JW, Thiele J, Arber DA, et al. The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: rationale and important changes. Blood. 2009;114(5): 937-951.
    • (2009) Blood , vol.114 , Issue.5 , pp. 937-951
    • Vardiman, J.W.1    Thiele, J.2    Arber, D.A.3
  • 14
    • 84974560145 scopus 로고    scopus 로고
    • The 2016 revision to the world health organization classification of myeloid neoplasms and acute leukemia
    • Arber DA, Orazi A, Hasserjian R, et al. The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia. Blood. 2016;127(20): 2391-2405.
    • (2016) Blood , vol.127 , Issue.20 , pp. 2391-2405
    • Arber, D.A.1    Orazi, A.2    Hasserjian, R.3
  • 15
    • 85010931761 scopus 로고    scopus 로고
    • The shadowlands of MDS: Idiopathic cytopenias of undetermined significance (ICUS) and clonal hematopoiesis of indeterminate potential (CHIP)
    • Malcovati L, Cazzola M. The shadowlands of MDS: idiopathic cytopenias of undetermined significance (ICUS) and clonal hematopoiesis of indeterminate potential (CHIP). Hematology Am Soc Hematol Educ Program. 2015;2015: 299-307.
    • (2015) Hematology Am Soc Hematol Educ Program , vol.2015 , pp. 299-307
    • Malcovati, L.1    Cazzola, M.2
  • 16
    • 34249786233 scopus 로고    scopus 로고
    • Definitions and standards in the diagnosis and treatment of the myelodysplastic syndromes: Consensus statements and report from a working conference
    • Valent P, Horny HP, Bennett JM, et al. Definitions and standards in the diagnosis and treatment of the myelodysplastic syndromes: consensus statements and report from a working conference. Leuk Res. 2007;31(6): 727-736.
    • (2007) Leuk Res , vol.31 , Issue.6 , pp. 727-736
    • Valent, P.1    Horny, H.P.2    Bennett, J.M.3
  • 17
    • 79959794787 scopus 로고    scopus 로고
    • Clinical effect of point mutations in myelodysplastic syndromes
    • Bejar R, Stevenson K, Abdel-Wahab O, et al. Clinical effect of point mutations in myelodysplastic syndromes. N Engl J Med. 2011; 364(26): 2496-2506.
    • (2011) N Engl J Med , vol.364 , Issue.26 , pp. 2496-2506
    • Bejar, R.1    Stevenson, K.2    Abdel-Wahab, O.3
  • 18
    • 80053900941 scopus 로고    scopus 로고
    • Frequent pathway mutations of splicing machinery in myelodysplasia
    • Yoshida K, Sanada M, Shiraishi Y, et al. Frequent pathway mutations of splicing machinery in myelodysplasia. Nature. 2011;478(7367): 64-69.
    • (2011) Nature , vol.478 , Issue.7367 , pp. 64-69
    • Yoshida, K.1    Sanada, M.2    Shiraishi, Y.3
  • 19
    • 80054010617 scopus 로고    scopus 로고
    • Somatic sf3b1 mutation in myelodysplasia with ring sideroblasts
    • Chronic Myeloid Disorders Working Group of the International Cancer Genome Consortium
    • Papaemmanuil E, Cazzola M, Boultwood J, et al; Chronic Myeloid Disorders Working Group of the International Cancer Genome Consortium. Somatic SF3B1 mutation in myelodysplasia with ring sideroblasts. N Engl J Med. 2011;365(15): 1384-1395.
    • (2011) N Engl J Med , vol.365 , Issue.15 , pp. 1384-1395
    • Papaemmanuil, E.1    Cazzola, M.2    Boultwood, J.3
  • 20
    • 84863337617 scopus 로고    scopus 로고
    • Clonal architecture of secondary acute myeloid leukemia
    • Walter MJ, Shen D, Ding L, et al. Clonal architecture of secondary acute myeloid leukemia. N Engl J Med. 2012;366(12): 1090-1098.
    • (2012) N Engl J Med , vol.366 , Issue.12 , pp. 1090-1098
    • Walter, M.J.1    Shen, D.2    Ding, L.3
  • 21
    • 84555192302 scopus 로고    scopus 로고
    • Recurrent mutations in the U2AF1 splicing factor in myelodysplastic syndromes
    • Graubert TA, Shen D, Ding L, et al. Recurrent mutations in the U2AF1 splicing factor in myelodysplastic syndromes. Nat Genet. 2011; 44(1): 53-57.
    • (2011) Nat Genet , vol.44 , Issue.1 , pp. 53-57
    • Graubert, T.A.1    Shen, D.2    Ding, L.3
  • 22
    • 84888219405 scopus 로고    scopus 로고
    • Clinical and biological implications of driver mutations in myelodysplastic syndromes
    • Chronic Myeloid Disorders Working Group of the International Cancer Genome Consortium. quiz 3699
    • Papaemmanuil E, Gerstung M, Malcovati L, et al; Chronic Myeloid Disorders Working Group of the International Cancer Genome Consortium. Clinical and biological implications of driver mutations in myelodysplastic syndromes. Blood. 2013;122(22): 3616-3627, quiz 3699.
    • (2013) Blood , vol.122 , Issue.22 , pp. 3616-3627
    • Papaemmanuil, E.1    Gerstung, M.2    Malcovati, L.3
  • 23
    • 84893772765 scopus 로고    scopus 로고
    • Landscape of genetic lesions in 944 patients with myelodysplastic syndromes
    • Haferlach T, Nagata Y, Grossmann V, et al. Landscape of genetic lesions in 944 patients with myelodysplastic syndromes. Leukemia. 2014; 28(2): 241-247.
    • (2014) Leukemia , vol.28 , Issue.2 , pp. 241-247
    • Haferlach, T.1    Nagata, Y.2    Grossmann, V.3
  • 24
    • 84920053873 scopus 로고    scopus 로고
    • Age-related clonal hematopoiesis associated with adverse outcomes
    • Jaiswal S, Fontanillas P, Flannick J, et al. Age-related clonal hematopoiesis associated with adverse outcomes. N Engl J Med. 2014;371(26): 2488-2498.
    • (2014) N Engl J Med , vol.371 , Issue.26 , pp. 2488-2498
    • Jaiswal, S.1    Fontanillas, P.2    Flannick, J.3
  • 25
    • 84920024296 scopus 로고    scopus 로고
    • Clonal hematopoiesis and blood-cancer risk inferred from blood DNA sequence
    • Genovese G, Kähler AK, Handsaker RE, et al. Clonal hematopoiesis and blood-cancer risk inferred from blood DNA sequence. N Engl J Med. 2014;371(26): 2477-2487.
    • (2014) N Engl J Med , vol.371 , Issue.26 , pp. 2477-2487
    • Genovese, G.1    Kähler, A.K.2    Handsaker, R.E.3
  • 26
    • 84930003179 scopus 로고    scopus 로고
    • Age-related mutations associated with clonal hematopoietic expansion and malignancies
    • Xie M, Lu C, Wang J, et al. Age-related mutations associated with clonal hematopoietic expansion and malignancies. Nat Med. 2014;20(12): 1472-1478.
    • (2014) Nat Med , vol.20 , Issue.12 , pp. 1472-1478
    • Xie, M.1    Lu, C.2    Wang, J.3
  • 27
    • 84924620531 scopus 로고    scopus 로고
    • Leukemia-associated somatic mutations drive distinct patterns of age-related clonal hemopoiesis
    • Understanding Society Scientific Group
    • McKerrell T, Park N, Moreno T, et al; Understanding Society Scientific Group. Leukemia-associated somatic mutations drive distinct patterns of age-related clonal hemopoiesis. Cell Reports. 2015;10(8): 1239-1245.
    • (2015) Cell Reports , vol.10 , Issue.8 , pp. 1239-1245
    • McKerrell, T.1    Park, N.2    Moreno, T.3
  • 28
    • 84937904208 scopus 로고    scopus 로고
    • Clonal hematopoiesis of indeterminate potential and its distinction from myelodysplastic syndromes
    • Steensma DP, Bejar R, Jaiswal S, et al. Clonal hematopoiesis of indeterminate potential and its distinction from myelodysplastic syndromes. Blood. 2015;126(1): 9-16.
    • (2015) Blood , vol.126 , Issue.1 , pp. 9-16
    • Steensma, D.P.1    Bejar, R.2    Jaiswal, S.3
  • 29
    • 84979231394 scopus 로고    scopus 로고
    • Clonal hematopoiesis in acquired aplastic anemia
    • Ogawa S. Clonal hematopoiesis in acquired aplastic anemia. Blood. 2016;128(3): 337-347.
    • (2016) Blood , vol.128 , Issue.3 , pp. 337-347
    • Ogawa, S.1
  • 30
    • 84949035448 scopus 로고    scopus 로고
    • MDS-associated somatic mutations and clonal hematopoiesis are common in idiopathic cytopenias of undetermined significance
    • Kwok B, Hall JM, Witte JS, et al. MDS-associated somatic mutations and clonal hematopoiesis are common in idiopathic cytopenias of undetermined significance. Blood. 2015;126(21): 2355-2361.
    • (2015) Blood , vol.126 , Issue.21 , pp. 2355-2361
    • Kwok, B.1    Hall, J.M.2    Witte, J.S.3
  • 31
    • 84948771021 scopus 로고    scopus 로고
    • Targeted sequencing identifies patients with preclinical MDS at high risk of disease progression
    • Cargo CA, Rowbotham N, Evans PA, et al. Targeted sequencing identifies patients with preclinical MDS at high risk of disease progression. Blood. 2015;126(21): 2362-2365.
    • (2015) Blood , vol.126 , Issue.21 , pp. 2362-2365
    • Cargo, C.A.1    Rowbotham, N.2    Evans, P.A.3
  • 32
    • 83455234787 scopus 로고    scopus 로고
    • Clinical significance of sf3b1 mutations in myelodysplastic syndromes and myelodysplastic/myeloproliferative neoplasms
    • Chronic Myeloid Disorders Working Group of the International Cancer Genome Consortium and of the Associazione Italiana per la Ricerca sul Cancro Gruppo Italiano Malattie Mieloproliferative
    • Malcovati L, Papaemmanuil E, Bowen DT, et al; Chronic Myeloid Disorders Working Group of the International Cancer Genome Consortium and of the Associazione Italiana per la Ricerca sul Cancro Gruppo Italiano Malattie Mieloproliferative. Clinical significance of SF3B1 mutations in myelodysplastic syndromes and myelodysplastic/myeloproliferative neoplasms. Blood. 2011;118(24): 6239-6246.
    • (2011) Blood , vol.118 , Issue.24 , pp. 6239-6246
    • Malcovati, L.1    Papaemmanuil, E.2    Bowen, D.T.3
  • 33
    • 84907346397 scopus 로고    scopus 로고
    • Driver somatic mutations identify distinct disease entities within myeloid neoplasms with myelodysplasia
    • Malcovati L, Papaemmanuil E, Ambaglio I, et al. Driver somatic mutations identify distinct disease entities within myeloid neoplasms with myelodysplasia. Blood. 2014;124(9): 1513-1521.
    • (2014) Blood , vol.124 , Issue.9 , pp. 1513-1521
    • Malcovati, L.1    Papaemmanuil, E.2    Ambaglio, I.3
  • 34
    • 84937805127 scopus 로고    scopus 로고
    • Sf3b1 mutation identifies a distinct subset of myelodysplastic syndrome with ring sideroblasts
    • Malcovati L, Karimi M, Papaemmanuil E, et al. SF3B1 mutation identifies a distinct subset of myelodysplastic syndrome with ring sideroblasts. Blood. 2015;126(2): 233-241.
    • (2015) Blood , vol.126 , Issue.2 , pp. 233-241
    • Malcovati, L.1    Karimi, M.2    Papaemmanuil, E.3
  • 35
    • 84929162813 scopus 로고    scopus 로고
    • Srsf2 mutations contribute to myelodysplasia by mutant-specific effects on exon recognition
    • Kim E, Ilagan JO, Liang Y, et al. SRSF2 mutations contribute to myelodysplasia by mutant-specific effects on exon recognition. Cancer Cell. 2015; 27(5): 617-630.
    • (2015) Cancer Cell , vol.27 , Issue.5 , pp. 617-630
    • Kim, E.1    Ilagan, J.O.2    Liang, Y.3
  • 36
    • 84995618121 scopus 로고    scopus 로고
    • Physiologic expression of Sf3b1(K700E) causes impaired erythropoiesis, aberrant splicing, and sensitivity to therapeutic spliceosome modulation
    • Obeng EA, Chappell RJ, Seiler M, et al. Physiologic expression of Sf3b1(K700E) causes impaired erythropoiesis, aberrant splicing, and sensitivity to therapeutic spliceosome modulation. Cancer Cell. 2016;30(3): 404-417.
    • (2016) Cancer Cell , vol.30 , Issue.3 , pp. 404-417
    • Obeng, E.A.1    Chappell, R.J.2    Seiler, M.3
  • 37
    • 84929149702 scopus 로고    scopus 로고
    • Mutant u2af1 expression alters hematopoiesis and pre-mRNA splicing in vivo
    • Shirai CL, Ley JN, White BS, et al. Mutant U2AF1 expression alters hematopoiesis and pre-mRNA splicing in vivo. Cancer Cell. 2015;27(5): 631-643.
    • (2015) Cancer Cell , vol.27 , Issue.5 , pp. 631-643
    • Shirai, C.L.1    Ley, J.N.2    White, B.S.3
  • 38
    • 84936160001 scopus 로고    scopus 로고
    • Somatic mutations and clonal hematopoiesis in aplastic anemia
    • Yoshizato T, Dumitriu B, Hosokawa K, et al. Somatic mutations and clonal hematopoiesis in aplastic anemia. N Engl J Med. 2015;373(1): 35-47.
    • (2015) N Engl J Med , vol.373 , Issue.1 , pp. 35-47
    • Yoshizato, T.1    Dumitriu, B.2    Hosokawa, K.3
  • 39
    • 84902480315 scopus 로고    scopus 로고
    • Myelodysplastic syndromes are propagated by rare and distinct human cancer stem cells in vivo
    • [published corrections appear in Cancer Cell. 2015;27(4):603-605; Cancer Cell. 2014;25(6): 861]
    • Woll PS, Kjällquist U, Chowdhury O, et al. Myelodysplastic syndromes are propagated by rare and distinct human cancer stem cells in vivo [published corrections appear in Cancer Cell. 2015;27(4): 603-605; Cancer Cell. 2014;25(6): 861]. Cancer Cell. 2014;25(6): 794-808.
    • (2014) Cancer Cell , vol.25 , Issue.6 , pp. 794-808
    • Woll, P.S.1    Kjällquist, U.2    Chowdhury, O.3
  • 40
    • 84993661482 scopus 로고    scopus 로고
    • Integrated genomic DNA/RNA profiling of hematologic malignancies in the clinical setting
    • He J, Abdel-Wahab O, Nahas MK, et al. Integrated genomic DNA/RNA profiling of hematologic malignancies in the clinical setting. Blood. 2016;127(24): 3004-3014.
    • (2016) Blood , vol.127 , Issue.24 , pp. 3004-3014
    • He, J.1    Abdel-Wahab, O.2    Nahas, M.K.3


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