-
1
-
-
77955917935
-
Type iia topoisomerase inhibition by a new class of antibacterial agents
-
Bax BD, Chan PF, Eggleston DS, Fosberry A, Gentry DR, Gorrec F, Gior-dano I, Hann MM, Hennessy A, Hibbs M, Huang J, Jones E, Jones J, Brown KK, Lewis CJ, May EW, Saunders MR, Singh O, Spitzfaden CE, Shen C, Shillings A, Theobald AJ, Wohlkonig A, Pearson ND, Gwynn MN. 2010. Type IIA topoisomerase inhibition by a new class of antibacterial agents. Nature 466:935–940. https://doi.org/10.1038/nature09197.
-
(2010)
Nature
, vol.466
, pp. 935-940
-
-
Bax, B.D.1
Chan, P.F.2
Eggleston, D.S.3
Fosberry, A.4
Gentry, D.R.5
Gorrec, F.6
Gior-Dano, I.7
Hann, M.M.8
Hennessy, A.9
Hibbs, M.10
Huang, J.11
Jones, E.12
Jones, J.13
Brown, K.K.14
Lewis, C.J.15
May, E.W.16
Saunders, M.R.17
Singh, O.18
Spitzfaden, C.E.19
Shen, C.20
Shillings, A.21
Theobald, A.J.22
Wohlkonig, A.23
Pearson, N.D.24
Gwynn, M.N.25
more..
-
2
-
-
84960427471
-
In vitro activity of gepotidacin, a novel triazaacenaphthylene bacterial topoisomerase inhibitor, against a broad spectrum of bacterial pathogens
-
Biedenbach DJ, Bouchillon SK, Hackel M, Miller LA, Scangarella-Oman NE, Jakielaszek C, Sahm DF. 2016. In vitro activity of gepotidacin, a novel triazaacenaphthylene bacterial topoisomerase inhibitor, against a broad spectrum of bacterial pathogens. Antimicrob Agents Chemother 60: 1918–1923. https://doi.org/10.1128/AAC.02820-15.
-
(2016)
Antimicrob Agents Chemother
, vol.60
, pp. 1918-1923
-
-
Biedenbach, D.J.1
Bouchillon, S.K.2
Hackel, M.3
Miller, L.A.4
Scangarella-Oman, N.E.5
Jakielaszek, C.6
Sahm, D.F.7
-
3
-
-
84977137214
-
Multicenter investigation of gepotidacin (gsk2140944) agar dilution quality control determinations for neisseria gonorrhoeae Atcc 49226
-
Jones RN, Fedler KA, Scangarella-Oman NE, Ross JE, Flamm RK. 2016. Multicenter investigation of gepotidacin (GSK2140944) agar dilution quality control determinations for Neisseria gonorrhoeae ATCC 49226. Antimicrob Agents Chemother 60:4404–4406. https://doi.org/10.1128/AAC.00527-16.
-
(2016)
Antimicrob Agents Chemother
, vol.60
, pp. 4404-4406
-
-
Jones, R.N.1
Fedler, K.A.2
Scangarella-Oman, N.E.3
Ross, J.E.4
Flamm, R.K.5
-
4
-
-
85021666960
-
Gepotidacin (gsk2140944) in vitro activity against gram-positive and gram-negative bacteria (mbc/mic, kill kinetics, checkerboard, pae/ sme tests
-
ASM Microbe, Boston, MA, 16 to 20 June 2016
-
Flamm RK, Sader HS, Rhomberg PR, Scangarella-Oman NE, Farrell DJ. 2016. Gepotidacin (GSK2140944) in vitro activity against Gram-positive and Gram-negative bacteria (MBC/MIC, kill kinetics, checkerboard, PAE/ SME tests), abstr 460. ASM Microbe, Boston, MA, 16 to 20 June 2016.
-
(2016)
-
-
Flamm, R.K.1
Sader, H.S.2
Rhomberg, P.R.3
Scangarella-Oman, N.E.4
Farrell, D.J.5
-
5
-
-
85021642557
-
Gepotidacin (gsk2140944) in vitro activity against neisseria gonorrhoeae (mic/mbc, kill kinetics, checkerboard, pae/sme tests
-
ASM Microbe, Boston, MA, 16 to 20 June 2016
-
Farrell DJ, Sader HS, Rhomberg PR, Scangarella-Oman NE, Flamm RK. 2016. Gepotidacin (GSK2140944) in vitro activity against Neisseria gonorrhoeae (MIC/MBC, kill kinetics, checkerboard, PAE/SME tests), abstr 461. ASM Microbe, Boston, MA, 16 to 20 June 2016.
-
(2016)
-
-
Farrell, D.J.1
Sader, H.S.2
Rhomberg, P.R.3
Scangarella-Oman, N.E.4
Flamm, R.K.5
-
6
-
-
84940938500
-
Insights into the mechanism of inhibition of novel bacterial topoisomerase inhibitors from characterization of resistant mutants of staphylococcus aureus
-
Lahiri SD, Kutschke A, McCormack K, Alm RA. 2015. Insights into the mechanism of inhibition of novel bacterial topoisomerase inhibitors from characterization of resistant mutants of Staphylococcus aureus. Antimicrob Agents Chemother 59:5278–5287. https://doi.org/10.1128/AAC.00571-15.
-
(2015)
Antimicrob Agents Chemother
, vol.59
, pp. 5278-5287
-
-
Lahiri, S.D.1
Kutschke, A.2
McCormack, K.3
Alm, R.A.4
-
7
-
-
84920173087
-
Target-based resistance in pseudomonas aeruginosa and escherichia coli to nbti 5463, a novel bacterial type ii topoisomerase inhibitor
-
Nayar AS, Dougherty TJ, Reck F, Thresher J, Gao N, Shapiro AB, Ehmann DE. 2015. Target-based resistance in Pseudomonas aeruginosa and Escherichia coli to NBTI 5463, a novel bacterial type II topoisomerase inhibitor. Antimicrob Agents Chemother 59:331–337. https://doi.org/10.1128/AAC.04077-14.
-
(2015)
Antimicrob Agents Chemother
, vol.59
, pp. 331-337
-
-
Nayar, A.S.1
Dougherty, T.J.2
Reck, F.3
Thresher, J.4
Gao, N.5
Shapiro, A.B.6
Ehmann, D.E.7
-
8
-
-
84898640721
-
Nbti 5463 is a novel bacterial type ii topoisomerase inhibitor with activity against gram-negative bacteria and in vivo efficacy
-
Dougherty TJ, Nayar A, Newman JV, Hopkins S, Stone GG, Johnstone M, Shapiro AB, Cronin M, Reck F, Ehmann DE. 2014. NBTI 5463 is a novel bacterial type II topoisomerase inhibitor with activity against Gram-negative bacteria and in vivo efficacy. Antimicrob Agents Chemother 58:2657–2664. https://doi.org/10.1128/AAC.02778-13.
-
(2014)
Antimicrob Agents Chemother
, vol.58
, pp. 2657-2664
-
-
Dougherty, T.J.1
Nayar, A.2
Newman, J.V.3
Hopkins, S.4
Stone, G.G.5
Johnstone, M.6
Shapiro, A.B.7
Cronin, M.8
Reck, F.9
Ehmann, D.E.10
-
12
-
-
33745615533
-
Tests to assess bactericidal activity
-
Leber AL (ed) 4th ed ASM Press, Washington, DC
-
Koeth LM. 2016. Tests to assess bactericidal activity. In Leber AL (ed), Clinical microbiology procedures handbook, 4th ed, vol 2. ASM Press, Washington, DC.
-
(2016)
Clinical Microbiology Procedures Handbook
, vol.2
-
-
Koeth, L.M.1
-
13
-
-
33745615533
-
Susceptibility tests to evaluate synergism
-
Isenberg HD (ed) ASM Press, Washington, DC
-
Moody J. 2004. Susceptibility tests to evaluate synergism, p 5.12.11–15.12.23. In Isenberg HD (ed), Clinical microbiology procedures handbook, vol 5. ASM Press, Washington, DC.
-
(2004)
Clinical Microbiology Procedures Handbook
, vol.5
, pp. 5.12.11-15.12.23
-
-
Moody, J.1
-
14
-
-
0027236995
-
Studies on the postantibiotic effect and the postantibiotic sub-mic effect of meropenem
-
Odenholt-Tornqvist I. 1993. Studies on the postantibiotic effect and the postantibiotic sub-MIC effect of meropenem. J Antimicrob Chemother 31:881–892. https://doi.org/10.1093/jac/31.6.881.
-
(1993)
J Antimicrob Chemother
, vol.31
, pp. 881-892
-
-
Odenholt-Tornqvist, I.1
-
15
-
-
0026760113
-
Postantibiotic sub-mic effects of vancomycin, roxithromycin, sparfloxacin, and amikacin
-
Odenholt-Tornqvist I, Lowdin E, Cars O. 1992. Postantibiotic sub-MIC effects of vancomycin, roxithromycin, sparfloxacin, and amikacin. Antimicrob Agents Chemother 36:1852–1858. https://doi.org/10.1128/AAC.36.9.1852.
-
(1992)
Antimicrob Agents Chemother
, vol.36
, pp. 1852-1858
-
-
Odenholt-Tornqvist, I.1
Lowdin, E.2
Cars, O.3
-
16
-
-
0031960126
-
Postantibiotic effect and postantibiotic sub-mic effect of levofloxacin compared to those of ofloxacin, ciprofloxacin, erythromycin, azithromycin, and clarithromycin against 20 pneumococci
-
Spangler SK, Lin G, Jacobs MR, Appelbaum PC. 1998. Postantibiotic effect and postantibiotic sub-MIC effect of levofloxacin compared to those of ofloxacin, ciprofloxacin, erythromycin, azithromycin, and clarithromycin against 20 pneumococci. Antimicrob Agents Chemother 42:1253–1255.
-
(1998)
Antimicrob Agents Chemother
, vol.42
, pp. 1253-1255
-
-
Spangler, S.K.1
Lin, G.2
Jacobs, M.R.3
Appelbaum, P.C.4
|