Pectolinarigenin from the leaves of Clerodendrum volubile shows potent immunomodulatory activity by inhibiting T − cell proliferation and modulating respiratory oxidative burst in phagocytes

Biomedicine and Pharmacotherapy

Volumn 93, Issue , 2017, Pages 529-535

  Erukainure, Ochuko L ^a,b,c   Mesaik, M Ahmed ^b,d   Atolani, Olubunmi ^e   Muhammad, Aliyu ^b,f   Chukwuma, Chika I ^c   Islam, Md Shahidul ^c  

^a FEDERAL INSTITUTE OF INDUSTRIAL RESEARCH   (Nigeria)

^b UNIVERSITY OF KARACHI   (Pakistan)

^c UNIVERSITY OF KWAZULU NATAL   (South Africa)

^d UNIVERSITY OF TABUK   (Saudi Arabia)

^e UNIVERSITY OF ILORIN   (Nigeria)

^f AHMADU BELLO UNIVERSITY   (Nigeria)

Author keywords

Clerodendrum volubile; Pectolinarigenin immunomodulation; Phagocytes; T cell proliferation

Indexed keywords

ACETIC ACID ETHYL ESTER; ANTIOXIDANT; BUTANOL; DICHLOROMETHANE; FLAVONE DERIVATIVE; HEXANE; IMMUNOMODULATING AGENT; PECTOLINARIGENIN; SILICA GEL; UNCLASSIFIED DRUG; CHROMONE DERIVATIVE; IMMUNOLOGIC FACTOR;

ADULT; ANTIOXIDANT ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CHEMOLUMINESCENCE; CLERODENDRUM; CLERODENDRUM VOLUBILE; COLUMN CHROMATOGRAPHY; CONTROLLED STUDY; DRUG ISOLATION; DRUG SCREENING; DRUG STRUCTURE; HUMAN; IMMUNOMODULATION; IN VITRO STUDY; MACROPHAGE; MASS SPECTROMETRY; MEDICINAL PLANT; NEUTROPHIL; PHAGOCYTE; PLANT LEAF; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; RESPIRATORY BURST; T LYMPHOCYTE; CELL DEATH; CELL PROLIFERATION; CHEMISTRY; CYTOLOGY; DRUG EFFECTS; ISOLATION AND PURIFICATION; METABOLISM;

ADULT; CELL DEATH; CELL PROLIFERATION; CHROMONES; CLERODENDRUM; HUMANS; IMMUNOLOGIC FACTORS; MACROPHAGES; NEUTROPHILS; PHAGOCYTES; PLANT LEAVES; RESPIRATORY BURST; T-LYMPHOCYTES;

EID: 85021638903     PISSN: 07533322     EISSN: 19506007     Source Type: Journal    
DOI: 10.1016/j.biopha.2017.06.060     Document Type: Article

References (32)

1. Biella, C.A., Salvador, M.J., Dias, D.A., Dias-Baruffi, M., Pereira-Crott, L.S., Evaluation of immunomodulatory and anti-inflammatory effects and phytochemical screening of Alternanthera tenella Colla (Amaranthaceae) aqueous extracts. Mem. Inst. Oswaldo Cruz 103 (2008), 569–577.
2. Ciz, M., Denev, P., Kratchanova, M., Vasicek, O., Ambrozova, G., Lojek, A., Flavonoids inhibit the respiratory burst of neutrophils in mammals. Oxidat. Med. Cell. Long., 2012, 10.1155/2012/181295.
3. Adrian, A., Schoppmann, K., Sromicki, J., Brungs, S., von der Wiesche, M., Hock, B., et al. The oxidative burst reaction inmammalian cells depends on gravity. Cell Comm. Signal., 11(98), 2013, 10.1186/1478-811X-11-98.
4. Bhattacharjee, S., Reactive oxygen species and oxidative burst: roles in stress, senescence and signal transduction in plants. Curr. Sci. 89:7 (2005), 1113–1121.
5. Erukainure, O.L., Ebuehi, O.A.T., Choudhary, I.M., Adhikari, A., Hafizur, R.M., Perveen, S., Muhammad, A., Elemo, G.N., Iridoid glycoside from the leaves of Clerodendrum volubile beauv. shows potent antioxidant activity against oxidative stress in rat brain and hepatic tissues. J Diet. Supp., 2014, 10.3109/19390211.2013.859213.
6. Burkill, H.M., The useful plants of west tropical Africa. Kew, 1985, P.5.
7. Erukainure, O.L., Zaruwa, M.Z., Choudhary, M.I., Naqvi, S.A., Ashraf, A., Hafizur, R.M., Muhammad, A., Ebuehi, O.A.T., Elemo, G.N., Dietary fatty acids from leaves of clerodendrum volubile induces cell cycle arrest downregulates matrix metalloproteinase (MMP)-9 expression, and modulates redox status in human Breast cancer. Nutr. Canc., 2016, 10.1080/01635581.2016.1156714.
8. Adefegha, S.A., Oboh, G., Antioxidant and inhibitory properties of Clerodendrum volubile leaf extracts on key enzymes relevant to non-insulin dependent diabetesmellitus and hypertension. J. Taibah Uni. Sci., 2015, 10.1016/j.jtusci.2015.10.008.
9. Lu, M., Kong, Q., Xu, X., Lu, H., Lu, Z., Yu, W., Zuo, B., Su, J., Guo, R., Pectolinarigenin − a flavonoid compound from cirsium japonicum with potential anti-proliferation activity in MCF-7 Breast cancer cell. Trop. J. Pharm. Res. 13:2 (2014), 225–228.
10. Kumar, S., Pandey, A.K., Chemistry and biological activities of flavonoids: an overview. Sci. World J., 2013, 10.1155/2013/162750.
11. Shrivastava, N., Patel, T., Clerodendrum and heathcare: an overview −Part II phytochemistry and biotechnology. Med. Arom. Plant. Sci. Biotech. 1:2 (2007), 209–223.
12. Juang, F.C., Chen, Y.F., Lin, F.M., Huang, K.F., Constituents from the leaves of lantana camara (iv). J. Chin. Med. 16:2-3 (2005), 149–155.
13. Yoo, Y.M., Nam, J.H., Kim, M.Y., Chol, J., Park, H.J., Pectolinarin and pectolinarigenin of Cirsium setidens prevent the hepatic injury in rats caused by D-Galactosamine via an antioxidant mechanism. Biol. poharm. Bull. 31:4 (2008), 760–764.
14. Aliyu, M., Odunola, O.A., Farooq, A.D., Mesaik, A.M., Choudhary, M.I., Inuwa, H.M., Azhar, M., Asif, M., Erukainure, O.L., Antioxidant, mitogenic and immuno-modulatory potentials of acacia honey. Nutr. Ther. Metab., 2014, 10.5301/NTM.2014.12285.
15. Helfand, S.L., Werkmeister, J., Roder, J.C., Chemiluminescence response of human natural killer cells. I. The relationship between target cell binding chemiluminescence, and cytolysis. J. Exper. Med. 156 (1982), 492–505.
16. Nielsen, M., Gerwien, J., Nielsen, M., et al. MHC class II ligation induces CD58 (LFA-3) mediated adhesion in human T cells. Exp. Clin. Immunogenet. 15 (1998), 61–68.
17. Mosmann, T., Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J. Immunol. Method 65 (1983), 55–63.
18. Drwal, M.N., Banerjee, P., Dunkel, M., Wettig, M.R., Preissner, R., ProTox: a web server for the in silico prediction of rodent oral toxicity. Nucl. Acid. Res W1 (2014), W53–W58.
19. Brown, G.D., Innate antifungal immunity: the key role of phagocytes. Annu. Rev. Immunol. 29 (2016), 1–21.
20. Vendantham, T.N.C., Subramanian, S.S., Harborne, J.B., 4’-Methylscutellarein and pectolinarigenin from Clerodendron inerme. Phytochem, 16, 1977, 294.
21. Pal, S., Chowdhury, A., Adityachaudhury, N., Isolation of rice weevil feeding inhibitors uncinatone and pectolinarigenin from Clerodendron siphonenthus. J. Agric. Food Chem. 37:1 (1989), 234–236.
22. Tripoli, E., Guardia, M.L., Giammanco, S., Majo, D.D., Giammanco, M., Citrus flavonoids: molecular structure, biological activity and nutritional properties: a review. Food Chem. 104:2 (2007), 466–479.
23. Atolani, O., Fabiyi, O.A., Olatunji, G.A., Isovitexin from Kigelia pinnata, a potential ecofriendly nematicidal agent. Trop. Agric. 91 (2014), 67–74.
24. Atolani, O., Fabiyi, O.A., Olatunji, G.A., Nematicidal isochromane glycoside from Kigelia pinnata leaves. Acta Agriculturae Slovenica 104:1 (2014), 25–31.
25. Hanna, B., Ewa, B., Aleksandra, S., Michał, G., Grzegorz, B., The influence of bupivacaine on the whole blood chemiluminescence in laboring women—a preliminary report. Ginekol. Pols. 83 (2012), 814–818.
26. Yang, P., Huang, S., Yan, X., Huang, G., Dong, X., Zheng, T., et al. Origin of the phagocytic respiratory burst and its role in gut epithelial phagocytosis in a basal chordate. Free Rad. Biol. Med. 70 (2014), 54–67.
27. Allen, R.C., Role of oxygen in phagocyte microbicidalaction. Environ. Heal. Persp. 102:Supp 10 (1994), 201–208.
28. Kolpen, M., Kühl, M., Bjarnsholt, T., Moser, C., Hansen, C.R., Liengaard, L., et al. Nitrous oxide production in sputum from cystic fibrosis patients with chronic Pseudomonas aeruginosa lung infection. PLoS One, 9(1), 2014, e84353.
29. Costa, D., Marques, A.P., Reis, R.L., Lima, J.L., Fernandes, E., Inhibition of human neutrophil oxidative burst by pyrazolone derivatives. Free Radic. Biol. Med. 40 (2006), 632–640.
30. Janeway, C.A. Jr, Travers, P., Walport, M., et al. Immunobiology: The Immune System in Health and Disease. 5th ed., 2001, Garland Science, New York.
31. Skapenko, A., Leipe, J., Lipsky, P.E., Schulze-Koops, H., The role of the T cell in autoimmune inflammation. Arthritis Res. Ther. 7 (2005), S4–S14.
32. Cettour-Rose, P., Nguyen, T.X., Serrander, L., Kaufmann, M.T., Dayer, J.M., Burger, D., Roux-Lombard, P., T cell contact-mediated activation of respiratory burst in human polymorphonuclear leukocytes is inhibited by high-density lipoproteins and involves CD18. J. Leukoc. Biol. 77 (2005), 52–58.