Maternal antibodies protect offspring from severe influenza infection and do not lead to detectable interference with subsequent offspring immunization

Virology Journal

Volumn 14, Issue 1, 2017, Pages

  Van Der Lubbe, Joan E M ^a   Vreugdenhil, Jessica ^a   Damman, Sarra ^a   Vaneman, Joost ^a   Klap, Jaco ^a   Goudsmit, Jaap ^a   Radošević, Katarina ^b   Roozendaal, Ramon ^a  

^a Janssen Research and Development   (Netherlands)

^b SANOFI   (France)

Author keywords

Influenza virus; Maternal antibodies; Passive protection; Placental transfer; Protection; Seasonal influenza vaccination; Vaccination during pregnancy; Vaccination gap

Indexed keywords

INFLUENZA VACCINE; MATERNAL ANTIBODY;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY TITER; ARTICLE; CONTROLLED STUDY; DRUG DOSE REDUCTION; DRUG DOSE TITRATION; EMBRYO; FEMALE; INFANT; INFECTION PREVENTION; INFLUENZA; INFLUENZA A (H1N1); INFLUENZA VACCINATION; INFLUENZA VIRUS; JUVENILE ANIMAL; MALE; MATERNAL TREATMENT; MOUSE; MOUSE MODEL; NONHUMAN; PASSIVE IMMUNIZATION; PLACENTAL TRANSFER; SURVIVAL; TIME; ANIMAL; DISEASE MODEL; IMMUNOLOGY; ORTHOMYXOVIRUS INFECTION; SURVIVAL ANALYSIS;

ANIMALS; DISEASE MODELS, ANIMAL; IMMUNITY, MATERNALLY-ACQUIRED; INFLUENZA VACCINES; MICE; ORTHOMYXOVIRIDAE INFECTIONS; SURVIVAL ANALYSIS;

EID: 85021314978     PISSN: None     EISSN: 1743422X     Source Type: Journal    
DOI: 10.1186/s12985-017-0787-4     Document Type: Article

References (51)

1. Poehling KA, et al. The underrecognized burden of influenza in young children. N Engl J Med. 2006;355(1):31-40.
2. Bhat N, et al. Influenza-associated deaths among children in the United States, 2003-2004. N Engl J Med. 2005;353(24):2559-67.
3. Chiu SS, et al. Population-based hospitalization incidence of respiratory viruses in community-acquired pneumonia in children younger than 5 years of age. Influenza Other Respir Viruses. 2014;8(6):626-7.
4. Dominguez A, Godoy P, Torner N. The Effectiveness of Influenza Vaccination in Different Groups. Expert Rev Vaccines. 2016;15(6):751-64.
5. Jamieson DJ, et al. H1N1 2009 influenza virus infection during pregnancy in the USA. Lancet. 2009;374(9688):451-8.
6. Siston AM, et al. Pandemic 2009 influenza a(H1N1) virus illness among pregnant women in the United States. JAMA. 2010;303(15):1517-25.
7. Sham PC, et al. Schizophrenia following pre-natal exposure to influenza epidemics between 1939 and 1960. Br J Psychiatry. 1992;160:461-6.
8. Mednick SA, et al. Adult schizophrenia following prenatal exposure to an influenza epidemic. Arch Gen Psychiatry. 1988;45(2):189-92.
9. Hardy JM, et al. The effect of Asian influenza on the outcome of pregnancy, Baltimore, 1957-1958. Am J Public Health Nations Health. 1961;51:1182-8.
10. Steinhoff MC, et al. Neonatal outcomes after influenza immunization during pregnancy: a randomized controlled trial. CMAJ. 2012;184(6):645-53.
11. Prevention, C.f.D.C.a. Children, the Flu, and the Flu Vaccine. 2015 August 21, 2015; Available from: http://www.cdc.gov/flu/protect/children.htm. (last update May 10, 2017).
12. Chiu SS, et al. Influenza-related hospitalizations among children in Hong Kong. N Engl J Med. 2002;347(26):2097-103.
13. Izurieta HS, et al. Influenza and the rates of hospitalization for respiratory disease among infants and young children. N Engl J Med. 2000;342(4):232-9.
14. Neuzil KM, et al. The effect of influenza on hospitalizations, outpatient visits, and courses of antibiotics in children. N Engl J Med. 2000;342(4):225-31.
15. Glezen WP, et al. Influenza virus infections in infants. Pediatr Infect Dis J. 1997;16(11):1065-8.
16. Neuzil KM, et al. Burden of interpandemic influenza in children younger than 5 years: a 25-year prospective study. J Infect Dis. 2002;185(2):147-52.
17. Prevention, C.f.D.C.a. 2013-14 Flu Season. 2014 January 28, 2016; Available from: http://www.cdc.gov/flu/fluvaxview/coverage-1314estimates.htm. (last update January 28, 2016).
18. Sweet C, et al. Production of passive immunity in neonatal ferrets following maternal vaccination with killed influenza a virus vaccines. Immunology. 1987;60(1):83-9.
19. Renshaw HW. Influence of antibody-mediated immune suppression on clinical, viral, and immune responses to swine influenza infection. Am J Vet Res. 1975;36(1):5-13.
20. Mbawuike IN, et al. Vaccination with inactivated influenza a virus during pregnancy protects neonatal mice against lethal challenge by influenza a viruses representing three subtypes. J Virol. 1990;64(3):1370-4.
21. Hwang SD, et al. Protection of pregnant mice, fetuses and neonates from lethality of H5N1 influenza viruses by maternal vaccination. Vaccine. 2010;28(17):2957-64.
22. Small PA Jr, et al. Influenza infection in ferrets: role of serum antibody in protection and recovery. Infect Immun. 1976;13(2):417-24.
23. Sumaya CV, Gibbs RS. Immunization of pregnant women with influenza a/New Jersey/76 virus vaccine: reactogenicity and immunogenicity in mother and infant. J Infect Dis. 1979;140(2):141-6.
24. Masurel N, et al. Haemagglutination-inhibition antibodies against influenza a and influenza B in maternal and neonatal sera. J Hyg (Lond). 1978;80(1):13-9.
25. Reuman PD, Ayoub EM, Small PA. Effect of passive maternal antibody on influenza illness in children: a prospective study of influenza a in mother-infant pairs. Pediatr Infect Dis J. 1987;6(4):398-403.
26. Barber WH, Small PA Jr. Local and systemic immunity to influenza infections in ferrets. Infect Immun. 1978;21(1):221-8.
27. Loeffen WL, et al. Effect of maternally derived antibodies on the clinical signs and immune response in pigs after primary and secondary infection with an influenza H1N1 virus. Vet Immunol Immunopathol. 2003;92(1-2):23-35.
28. Zhang F, et al. Intranasal immunization of mice to avoid interference of maternal antibody against H5N1 infection. PLoS One. 2016;11(6):e0157041.
29. Zaman K, et al. Effectiveness of maternal influenza immunization in mothers and infants. N Engl J Med. 2008;359(15):1555-64.
30. Poehling KA, et al. Impact of maternal immunization on influenza hospitalizations in infants. Am J Obstet Gynecol. 2011;204(6 Suppl 1):S141-8.
31. Dreyfus C, et al. Highly conserved protective epitopes on influenza B viruses. Science. 2012;337(6100):1343-8.
32. Ekiert DC, et al. A highly conserved neutralizing epitope on group 2 influenza a viruses. Science. 2011;333(6044):843-50.
33. Roozendaal R, et al. Transient humoral protection against H5N1 challenge after seasonal influenza vaccination of humans. PLoS One. 2014;9(7):e103550.
34. Bischoff AL, et al. Altered Response to A(H1N1)pnd09 Vaccination in Pregnant Women: A Single Blinded Randomized Controlled Trial. PLoS One. 2013;8(4):e56700.
35. Reuman PD, et al. Maternal-infant transfer of influenza-specific immunity in the mouse. J Immunol. 1983;130(2):932-6.
36. Holsapple MP, West LJ, Landreth KS. Species comparison of anatomical and functional immune system development. Birth Defects Res B Dev Reprod Toxicol. 2003;68(4):321-34.
37. Schlaudecker EP, et al. Pregnancy modifies the antibody response to trivalent influenza immunization. J Infect Dis. 2012;206(11):1670-3.
38. Christian LM. Optimizing benefits of influenza virus vaccination during pregnancy: potential behavioral risk factors and interventions. Vaccine. 2014;32(25):2958-64.
39. Reuman PD, et al. Maternal-infant transfer of influenza-specific immunity not detectable by haemagglutination inhibition. Microbios. 1988;54(220-221):135-47.
40. Brandenburg B, et al. Mechanisms of hemagglutinin targeted influenza virus neutralization. PLoS One. 2013;8(12):e80034.
41. Bertley FM, et al. Measles vaccination in the presence of maternal antibodies primes for a balanced humoral and cellular response to revaccination. Vaccine. 2004;23(4):444-9.
42. van Binnendijk RS, et al. Protective immunity in macaques vaccinated with live attenuated, recombinant, and subunit measles vaccines in the presence of passively acquired antibodies. J Infect Dis. 1997;175(3):524-32.
43. Gans H, et al. Measles and mumps vaccination as a model to investigate the developing immune system: passive and active immunity during the first year of life. Vaccine. 2003;21(24):3398-405.
44. Benowitz I, et al. Influenza vaccine given to pregnant women reduces hospitalization due to influenza in their infants. Clin Infect Dis. 51(12):1355-61.
45. Eick AA, et al. Maternal influenza vaccination and effect on influenza virus infection in young infants. Arch Pediatr Adolesc Med. 2011;165(2):104-11.
46. France EK, et al. Impact of maternal influenza vaccination during pregnancy on the incidence of acute respiratory illness visits among infants. Arch Pediatr Adolesc Med. 2006;160(12):1277-83.
47. Black SB, et al. Effectiveness of influenza vaccine during pregnancy in preventing hospitalizations and outpatient visits for respiratory illness in pregnant women and their infants. Am J Perinatol. 2004;21(6):333-9.
48. Puck JM, et al. Protection of infants from infection with influenza a virus by transplacentally acquired antibody. J Infect Dis. 1980;142(6):844-9.
49. Manske JM. Efficacy and effectiveness of maternal influenza vaccination during pregnancy: a review of the evidence. Matern Child Health J. 2014;18(7):1599-609.
50. Niewiesk S. Maternal antibodies: clinical significance, mechanism of interference with immune responses, and possible vaccination strategies. Front Immunol. 2014;5:446.
51. Siegrist CA. Mechanisms by which maternal antibodies influence infant vaccine responses: review of hypotheses and definition of main determinants. Vaccine. 2003;21(24):3406-12.