10-valent pneumococcal conjugate vaccine (PCV10) decreases metabolic activity but not nasopharyngeal carriage of Streptococcus pneumoniae and Haemophilus influenzae

Vaccine

Volumn 35, Issue 33, 2017, Pages 4105-4111

  Andrade, Dafne C ^a   Borges, Igor C ^a   Bouzas, Maiara L ^a   Oliveira, Juliana R ^a   Fukutani, Kiyoshi F ^b   Queiroz, Artur T ^b   de Oliveira, Camila Indiani ^a,b,c   Barral, Aldina ^a,b,c   Van Weyenbergh, Johan ^d   Nascimento Carvalho, Cristiana ^a  

^a FEDERAL UNIVERSITY OF BAHIA   (Brazil)

^b INSTITUTO OSWALDO CRUZ   (Brazil)

^c Institute of Investigation in Immunology iii   (Brazil)

^d REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

Author keywords

Capsular polysaccharides; Metabolism; Nasopharyngeal colonization; Protein D

Indexed keywords

DNA 16S; PNEUMOCOCCUS VACCINE; RNA 16S; 10-VALENT PNEUMOCOCCAL CONJUGATE VACCINE; BACTERIAL DNA; RIBOSOME DNA;

ARTICLE; BACTERIAL COUNT; BACTERIAL METABOLISM; BACTERIAL PNEUMONIA; BACTERIUM CARRIER; CONTROLLED STUDY; CORRELATION ANALYSIS; CROSS-SECTIONAL STUDY; FEMALE; FOLLOW UP; HAEMOPHILUS INFLUENZAE; HUMAN; INFANT; MAJOR CLINICAL STUDY; MALE; METABOLIC RATE; METAGENOMICS; MORAXELLA CATARRHALIS; NASOPHARYNGEAL ASPIRATION; NASOPHARYNX; PRIORITY JOURNAL; PROSPECTIVE STUDY; RESPIRATORY TRACT INFECTION; SEQUENCE ANALYSIS; STAPHYLOCOCCUS AUREUS; STREPTOCOCCUS PNEUMONIAE; TRANSCRIPTOMICS; CHEMISTRY; DNA SEQUENCE; GENETICS; HETEROZYGOTE; IMMUNOLOGY; ISOLATION AND PURIFICATION; METABOLISM; MICROBIOLOGY; PNEUMOCOCCAL INFECTION; PREVALENCE;

CARRIER STATE; CROSS-SECTIONAL STUDIES; DNA, BACTERIAL; DNA, RIBOSOMAL; FEMALE; HAEMOPHILUS INFLUENZAE; HUMANS; INFANT; MALE; MORAXELLA (BRANHAMELLA) CATARRHALIS; NASOPHARYNX; PNEUMOCOCCAL INFECTIONS; PNEUMOCOCCAL VACCINES; PREVALENCE; PROSPECTIVE STUDIES; RNA, RIBOSOMAL, 16S; SEQUENCE ANALYSIS, DNA; STAPHYLOCOCCUS AUREUS; STREPTOCOCCUS PNEUMONIAE;

EID: 85021297053     PISSN: 0264410X     EISSN: 18732518     Source Type: Journal    
DOI: 10.1016/j.vaccine.2017.06.048     Document Type: Article

References (25)

1. Simell, B., Auranen, K., Käyhty, H., Goldblatt, D., Dagan, R., O'Brien, K.L., et al. The fundamental link between pneumococcal carriage and disease. Expert Rev Vacc 11 (2012), 841–855.
2. Laval, C.B., de Andrade, A.L., Pimenta, F.C., de Andrade, J.G., de Oliveira, R.M., Silva, S.A., et al. Serotypes of carriage and invasive isolates of Streptococcus pneumoniae in Brazilian children in the era of pneumococcal vaccines. Clin Microbiol Infect 12 (2006), 50–55.
3. Tenenbaum, T., Franz, A., Neuhausen, N., Willems, R., Brade, J., Schweitzer-Krantz, S., et al. Clinical characteristics of children with lower respiratory tract infections are dependent on the carriage of specific pathogens in the nasopharynx. Eur J Clin Microbiol Infect Dis 31 (2012), 3173–3182.
4. Yu, D., Wei, L., Zhengxiu, L., Jian, L., Lijia, W., Wei, L., et al. Impact of bacterial colonization on the severity, and accompanying airway inflammation, of virus-induced wheezing in children. Clin Microbiol Infect 16 (2010), 1399–1404.
5. Jartti, T., Kuneinen, S., Lehtinen, P., Peltola, V., Vuorinen, T., Leinonen, M., et al. Nasopharyngeal bacterial colonization during the first wheezing episode is associated with longer duration of hospitalization and higher risk of relapse in young children. Eur J Clin Microbiol Infect Dis 30 (2011), 233–241.
6. van den Bergh, M.R., Biesbroek, G., Rossen, J.W., de Steenhuijsen Piters, W.A., Bosch, A.A., van Gils, E.J., et al. Associations between pathogens in the upper respiratory tract of young children: interplay between viruses and bacteria. PLoS One, 7, 2012, e47711.
7. Xu, Q., Almudervar, A., Casey, J.R., Pichichero, M.E., Nasopharyngeal bacterial interactions in children. Emerg Infect Dis 18 (2012), 1738–1745.
8. Vesikari, T., Forsten, A., Seppä I., Kaijalainen, T., Puumalainen, T., Soininen, A., et al. Effectiveness of the 10-valent pneumococcal non typeable haemophilus influenzae protein D-conjugated vaccine (PHiD-CV) against carriage and acute otitis media – a double-blind randomized clinical trial in Finland. J Pediatric Infect Dis Soc 5 (2016), 237–248.
9. Camilli, R., Vescio, M.F., Giufrè M., Daprai, L., Garlaschi, M.L., Cerquetti, M., et al. Carriage of Haemophilus influenzae is associated with pneumococcal vaccination in Italian children. Vaccine 33 (2015), 4559–4564.
10. van Gils, E.J., Veenhoven, R.H., Rodenburg, G.D., Hak, E., Sanders, E.A., Effect of 7-valent pneumococcal conjugate vaccine on nasopharyngeal carriage with Haemophilus influenzae and Moraxella catarrhalis in a randomized controlled trial. Vaccine 29 (2011), 7595–7598.
11. Barczak, A.K., Gomez, J.E., Kaufmann, B.B., Hinson, E.R., Cosimi, L., Borowsky, M.L., et al. RNA signatures allow rapid identification of pathogens and antibiotic susceptibilities. Proc Natl Acad Sci USA 109 (2012), 6217–6222.
12. Fukutani, K.F., Nascimento-Carvalho, C.M., Van der Gucht, W., Wollants, E., Khouri, R., Dierckx, T., et al. Pathogen transcriptional profile in nasopharyngeal aspirates of children with acute respiratory tract infection. J Clin Virol 69 (2015), 190–196.
13. Ilboudo, H., Camara, O., Ravel, S., Bucheton, B., Lejon, V., Camara, M., et al. Trypanosoma brucei gambiense spliced leader RNA is a more specific marker for cure of human african trypanosomiasis than T. b. gambiense DNA. J Infect Dis 212 (2015), 1996–1998.
14. Oliveira, J.R., Bouzas, M.L., Cardoso, M.R., Barral, A., Nascimento-Carvalho, C., Acute respiratory infection and wheeze study group phase I and II. Frequency of complications and the effects of pneumococcal vaccination in young children with acute respiratory tract infection. Vaccine 34 (2016), 2556–2561.
15. Meier, P.S., Troller, R., Grivea, I.N., Syrogiannopoulos, G.A., Aebi, C., The outer membrane proteins UspA1 and UspA2 of Moraxella catarrhalis are highly conserved in nasopharyngeal isolates from young children. Vaccine 20 (2002), 1754–1760.
16. Simões, A.S., Tavares, D.A., Rolo, D., Ardanuy, C., Goossens, H., Henriques-Normark, B., et al. lytA-based identification methods can misidentify Streptococcus pneumoniae. Diagn Microbiol Infect Dis 85 (2016), 141–148.
17. Caporaso, J.G., Kuczynski, J., Stombaugh, J., Bittinger, K., Bushman, F.D., Costello, E.K., et al. QIIME allows analysis of high-throughput community sequencing data. Nat Methods 7 (2010), 335–336.
18. Brandileone, M.C., Zanella, R.C., Almeida, S.C., Brandao, A.P., Ribeiro, A.F., Carvalhanas, T.M., et al. Effect of 10-valent pneumococcal conjugate vaccine on nasopharyngeal carriage of Streptococcus pneumoniae and Haemophilus influenzae among children in São Paulo, Brazil. Vaccine 34 (2016), 5604–5611.
19. Lindstrand, A., Galanis, I., Darenberg, J., Morfeldt, E., Naucler, P., Blennow, M., et al. Unaltered pneumococcal carriage prevalence due to expansion of non-vaccine types of low invasive potential 8years after vaccine introduction in Stockholm, Sweden. Vaccine 34 (2016), 4565–4571.
20. Watkins, E.R., Penman, B.S., Lourenço, J., Buckee, C.O., Maiden, M.C., Gupta, S., Vaccination drives changes in metabolic and virulence profiles of Streptococcus pneumoniae. PLoS Pathog, 11, 2015, e1005034.
21. van der Poll, T., Opal, S.M., Pathogenesis, treatment, and prevention of pneumococcal pneumonia. Lancet 374 (2009), 1543–1556.
22. Prymula, R., Kriz, P., Kaliskova, E., Pascal, T., Poolman, J., Schuerman, L., Effect of vaccination with pneumococcal capsular polysaccharides conjugated to Haemophilus influenzae-derived protein D on nasopharyngeal carriage of Streptococcus pneumoniae and H. influenzae in children under 2 years of age. Vaccine 28 (2009), 71–78.
23. Navne, J.E., Børresen, M.L., Slotved, H.C., Andersson, M., Melbye, M., Ladefoged, K., et al. Nasopharyngeal bacterial carriage in young children in Greenland: a population at high risk of respiratory infections. Epidemiol Infect 144 (2016), 3226–3236.
24. Zanella, R.C., Brandileone, M.C., Andrade, A.L., Ogassavara, C.T., Fiório, C.E., Brandão, A.P., et al. Evaluation of Haemophilus influenzae type b carrier status among children 10 years after the introduction of Hib vaccine in Brazil. Mem Inst Oswaldo Cruz. 110 (2015), 755–759.
25. Rodrigues, H.G., Pinto, T.C.A., Barros, R.R., Teixeira, L.M., Neves, F.P.G., Pneumococcal nasopharyngeal carriage among children in Brazil prior to the introduction of the 10-valent conjugate vaccine: a culture- and PCR-based survey. Epidemiol Infect 145 (2017), 1720–1726.