메뉴 건너뛰기




Volumn 95, Issue 5, 2017, Pages 501-509

Curcumin protects neuronal cells against Status-Epilepticus-Induced hippocampal damage through induction of autophagy and inhibition of necroptosis

Author keywords

Autophagy; Curcumin; Hippocampus; Necroptosis; Status epilepticus

Indexed keywords

BECLIN 1; CURCUMIN; LITHIUM; MIXED LINEAGE KINASE DOMAIN LIKE PROTEIN; PROTEIN; PROTEIN LC3; RECEPTOR INTERACTION PROTEIN KINASE 1; UNCLASSIFIED DRUG;

EID: 85021153503     PISSN: 00084212     EISSN: 12057541     Source Type: Journal    
DOI: 10.1139/cjpp-2016-0154     Document Type: Article
Times cited : (52)

References (35)
  • 1
    • 84876128794 scopus 로고    scopus 로고
    • Protective effects of curcumin against lithium-pilocarpine induced status epilepticus, cognitive dysfunction and oxidative stress in young rats
    • PMID: 23961231
    • Ahmad, M. 2013. Protective effects of curcumin against lithium-pilocarpine induced status epilepticus, cognitive dysfunction and oxidative stress in young rats. Saudi J. Biol. Sci. 20(2): 155-162. doi:10.1016/j.sjbs.2013.01.002. PMID: 23961231.
    • (2013) Saudi J. Biol. Sci , vol.20 , Issue.2 , pp. 155-162
    • Ahmad, M.1
  • 2
    • 84928943135 scopus 로고    scopus 로고
    • Inhibition of PI3K signaling triggered apoptotic potential of curcumin which is hindered by Bcl-2 through activation of autophagy in MCF-7 cells
    • PMID:25960232
    • Akkoç, Y., Berrak, Ö., Arısan, E.D., Obakan, P., Coker-Gürkan, A., and Palavan-Ünsal, N. 2015. Inhibition of PI3K signaling triggered apoptotic potential of curcumin which is hindered by Bcl-2 through activation of autophagy in MCF-7 cells. Biomed. Pharmacother. 71: 161-171. doi:10.1016/j.biopha. 2015.02.029. PMID:25960232.
    • (2015) Biomed. Pharmacother , vol.71 , pp. 161-171
    • Akkoç, Y.1    Berrak, Ö.2    Arısan, E.D.3    Obakan, P.4    Coker-Gürkan, A.5    Palavan-Ünsal, N.6
  • 3
    • 84926638378 scopus 로고    scopus 로고
    • Valproic acid induces neuronal cell death through a novel calpain-dependent necroptosis pathway
    • PMID:25581256
    • Bollino, D., Balan, I., and Aurelian, L. 2015. Valproic acid induces neuronal cell death through a novel calpain-dependent necroptosis pathway. J. Neurochem. 133(2): 174-186. doi:10.1111/jnc.13029. PMID:25581256.
    • (2015) J. Neurochem , vol.133 , Issue.2 , pp. 174-186
    • Bollino, D.1    Balan, I.2    Aurelian, L.3
  • 4
    • 84897011251 scopus 로고    scopus 로고
    • Protective effect of curcumin against contrast induced nephropathy in rat kidney: What is happening to oxidative stress, inflammation, autophagy and apoptosis
    • PMID:24610611
    • Buyuklu, M., Kandemir, F.M., Ozkaraca, M., Set, T., Bakirci, E.M., and Topal, E. 2014. Protective effect of curcumin against contrast induced nephropathy in rat kidney: what is happening to oxidative stress, inflammation, autophagy and apoptosis? Eur. Rev. Med. Pharmacol. Sci. 18(4): 461-470. PMID:24610611.
    • (2014) Eur. Rev. Med. Pharmacol. Sci , vol.18 , Issue.4 , pp. 461-470
    • Buyuklu, M.1    Kandemir, F.M.2    Ozkaraca, M.3    Set, T.4    Bakirci, E.M.5    Topal, E.6
  • 5
    • 70349865087 scopus 로고    scopus 로고
    • MTOR signaling in epileptogenesis: Too much of a good thing?
    • PMID:19812312
    • Cao, R., Li, A., and Cho, H.Y. 2009. mTOR signaling in epileptogenesis: too much of a good thing? J. Neurosci. 29(40): 12372-12373. doi:10.1523/JNEUROSCI.3486-09.2009. PMID:19812312.
    • (2009) J. Neurosci , vol.29 , Issue.40 , pp. 12372-12373
    • Cao, R.1    Li, A.2    Cho, H.Y.3
  • 6
    • 13844298651 scopus 로고    scopus 로고
    • Apoptosis-inducing factor is a key factor in neuronal cell death propagated by BAX-dependent and BAX-independent mechanisms
    • PMID:15703386
    • Cheung, E.C., Melanson-Drapeau, L., Cregan, S.P., Vanderluit, J.L., Ferguson, K.L., McIntosh, W.C., et al. 2005. Apoptosis-inducing factor is a key factor in neuronal cell death propagated by BAX-dependent and BAX-independent mechanisms. J. Neurosci. 25(6): 1324-1334. doi:10.1523/JNEUROSCI.4261-04.2005. PMID:15703386.
    • (2005) J. Neurosci , vol.25 , Issue.6 , pp. 1324-1334
    • Cheung, E.C.1    Melanson-Drapeau, L.2    Cregan, S.P.3    Vanderluit, J.L.4    Ferguson, K.L.5    McIntosh, W.C.6
  • 7
    • 84959252884 scopus 로고    scopus 로고
    • When and how do seizures kill neurons, and is cell death relevant to epileptogenesis?
    • Edited by H.E. Scharfman and P.S. Buckmaster. Springer, Dordrecht, Netherlands, PMID:25012371
    • Dingledine, R., Varvel, N.H., and Dudek, F.E. 2014. When and how do seizures kill neurons, and is cell death relevant to epileptogenesis? In Issues in clinical epidemiology: a view from the bench. Vol. 181 of Advances in experimental medicine and biology. Edited by H.E. Scharfman and P.S. Buckmaster. Springer, Dordrecht, Netherlands. pp. 109-122. doi:10.1007/978-94-017-8914-1_9. PMID:25012371.
    • (2014) Issues in Clinical Epidemiology: A View from the Bench. Vol. 181 of Advances in Experimental Medicine and Biology , pp. 109-122
    • Dingledine, R.1    Varvel, N.H.2    Dudek, F.E.3
  • 8
    • 84872116483 scopus 로고    scopus 로고
    • Anticonvulsive and antioxidant effects of curcumin on pilocarpine-induced seizures in rats
    • PMID:22884064
    • Du, P., Tang, H.Y., Li, X., Lin, H.J., Peng, W.F., Ma, Y., et al. 2012. Anticonvulsive and antioxidant effects of curcumin on pilocarpine-induced seizures in rats. Chin. Med. J. 125(11): 1975-1979. PMID:22884064.
    • (2012) Chin. Med. J , vol.125 , Issue.11 , pp. 1975-1979
    • Du, P.1    Tang, H.Y.2    Li, X.3    Lin, H.J.4    Peng, W.F.5    Ma, Y.6
  • 9
    • 84901318614 scopus 로고    scopus 로고
    • Glycogen accumulation underlies neurodegeneration and autophagy impairment in Lafora disease
    • PMID:24452334
    • Duran, J., Gruart, A., García-Rocha, M., Delgado-García, J.M., and Guinovart, J.J. 2014. Glycogen accumulation underlies neurodegeneration and autophagy impairment in Lafora disease. Hum. Mol. Genet. 23(12): 3147-3156. doi:10. 1093/hmg/ddu024. PMID:24452334.
    • (2014) Hum. Mol. Genet , vol.23 , Issue.12 , pp. 3147-3156
    • Duran, J.1    Gruart, A.2    García-Rocha, M.3    Delgado-García, J.M.4    Guinovart, J.J.5
  • 10
    • 84954567599 scopus 로고    scopus 로고
    • Curcumin suppresses proliferation and migration of MDA-MB-231 breast cancer cells through autophagy-dependent Akt degradation
    • PMID:26752181
    • Guan, F., Ding, Y., Zhang, Y., Zhou, Y., Li, M., and Wang, C. 2016. Curcumin suppresses proliferation and migration of MDA-MB-231 breast cancer cells through autophagy-dependent Akt degradation. PLoS One, 11(1): e0146553. doi:10.1371/journal.pone.0146553. PMID:26752181.
    • (2016) Plos One , vol.11 , Issue.1
    • Guan, F.1    Ding, Y.2    Zhang, Y.3    Zhou, Y.4    Li, M.5    Wang, C.6
  • 11
    • 79959626436 scopus 로고    scopus 로고
    • Autophagy and apoptosis: What is the connection?
    • PMID: 21561772
    • Gump, J.M., and Thorburn, A. 2011. Autophagy and apoptosis: what is the connection? Trends Cell Biol. 21(7): 387-392. doi:10.1016/j.tcb.2011.03.007. PMID: 21561772.
    • (2011) Trends Cell Biol , vol.21 , Issue.7 , pp. 387-392
    • Gump, J.M.1    Thorburn, A.2
  • 12
    • 84958719541 scopus 로고    scopus 로고
    • Curcumin activates autophagy and attenuates oxidative damage in EA.Hy926 cells via the Akt/ mTOR pathway
    • PMID:26781771
    • Guo, S., Long, M., Li, X., Zhu, S., Zhang, M., and Yang, Z. 2016. Curcumin activates autophagy and attenuates oxidative damage in EA.hy926 cells via the Akt/ mTOR pathway. Mol. Med. Rep. 13(3): 2187-2193. PMID:26781771.
    • (2016) Mol. Med. Rep , vol.13 , Issue.3 , pp. 2187-2193
    • Guo, S.1    Long, M.2    Li, X.3    Zhu, S.4    Zhang, M.5    Yang, Z.6
  • 13
    • 84866481943 scopus 로고    scopus 로고
    • MicroRNA expression profile of the hippocampus in a rat model of temporal lobe epilepsy and miR-34a-targeted neuroprotection against hippocampal neurone cell apoptosis post-status epilepticus
    • PMID:22998082
    • Hu, K., Xie, Y.Y., Zhang, C., Ouyang, D.S., Long, H.Y., Sun, D.N., et al. 2012. MicroRNA expression profile of the hippocampus in a rat model of temporal lobe epilepsy and miR-34a-targeted neuroprotection against hippocampal neurone cell apoptosis post-status epilepticus. BMC Neurosci. 13: 115. doi:10. 1186/1471-2202-13-115. PMID:22998082.
    • (2012) BMC Neurosci , vol.13 , pp. 115
    • Hu, K.1    Xie, Y.Y.2    Zhang, C.3    Ouyang, D.S.4    Long, H.Y.5    Sun, D.N.6
  • 14
    • 84923866869 scopus 로고    scopus 로고
    • LC3 overexpression reduces Abeta neurotoxicity through increasing alpha7nAchR expression and autophagic activity in neurons and mice
    • PMID:25686800
    • Hung, S.Y., Huang, W.P., Liou, H.C., and Fu, W.M. 2015. LC3 overexpression reduces Abeta neurotoxicity through increasing alpha7nAchR expression and autophagic activity in neurons and mice. Neuropharmacology, 93: 243-251. doi:10.1016/j.neuropharm.2015.02.003. PMID:25686800.
    • (2015) Neuropharmacology , vol.93 , pp. 243-251
    • Hung, S.Y.1    Huang, W.P.2    Liou, H.C.3    Fu, W.M.4
  • 15
    • 84943602594 scopus 로고    scopus 로고
    • Protection against cognitive impairment and modification of epileptogenesis with curcumin in a post-status epilepticus model of temporal lobe epilepsy
    • PMID:26415768
    • Jiang, Z., Guo, M., Shi, C., Wang, H., Yao, L., Liu, L., et al. 2015. Protection against cognitive impairment and modification of epileptogenesis with curcumin in a post-status epilepticus model of temporal lobe epilepsy. Neuroscience, 310: 362-371. doi:10.1016/j.neuroscience.2015.09.058. PMID:26415768.
    • (2015) Neuroscience , vol.310 , pp. 362-371
    • Jiang, Z.1    Guo, M.2    Shi, C.3    Wang, H.4    Yao, L.5    Liu, L.6
  • 16
    • 84942297587 scopus 로고    scopus 로고
    • Curcumin attenuates inflammatory response and cognitive deficits in experimental model of chronic epilepsy
    • PMID: 26190183
    • Kaur, H., Patro, I., Tikoo, K., and Sandhir, R. 2015. Curcumin attenuates inflammatory response and cognitive deficits in experimental model of chronic epilepsy. Neurochem. Int. 89: 40-50. doi:10.1016/j.neuint.2015.07.009. PMID: 26190183.
    • (2015) Neurochem. Int , vol.89 , pp. 40-50
    • Kaur, H.1    Patro, I.2    Tikoo, K.3    Sandhir, R.4
  • 18
    • 77954852402 scopus 로고    scopus 로고
    • An overview of curcumin in neurological disorders
    • PMID:20838516
    • Kulkarni, S.K., and Dhir, A. 2010. An overview of curcumin in neurological disorders. Indian J. Pharm. Sci. 72(2): 149-154. doi:10.4103/0250-474X.65012. PMID:20838516.
    • (2010) Indian J. Pharm. Sci , vol.72 , Issue.2 , pp. 149-154
    • Kulkarni, S.K.1    Dhir, A.2
  • 19
    • 78650638126 scopus 로고    scopus 로고
    • Closing in on the link between apoptosis and autophagy
    • PMID:21283600
    • Leber, B., and Andrews, D.W. 2010. Closing in on the link between apoptosis and autophagy. F1000 Biol. Rep. 2: 88. doi:10.3410/B2-88. PMID:21283600.
    • (2010) F1000 Biol. Rep , vol.2 , pp. 88
    • Leber, B.1    Andrews, D.W.2
  • 20
    • 84893149021 scopus 로고    scopus 로고
    • Necroptosis
    • PMID:24476434
    • Linkermann, A., and Green, D.R. 2014. Necroptosis. N. Engl. J. Med. 370(5): 455-465. doi:10.1056/NEJMra1310050. PMID:24476434.
    • (2014) N. Engl. J. Med. , vol.370 , Issue.5 , pp. 455-465
    • Linkermann, A.1    Green, D.R.2
  • 21
    • 84871721552 scopus 로고    scopus 로고
    • MTOR: On target for novel therapeutic strategies in the nervous system
    • PMID:23265840
    • Maiese, K., Chong, Z.Z., Shang, Y.C., and Wang, S. 2013. mTOR: on target for novel therapeutic strategies in the nervous system. Trends Mol. Med. 19(1), 51-60. doi:10.1016/j.molmed.2012.11.001. PMID:23265840.
    • (2013) Trends Mol. Med , vol.19 , Issue.1 , pp. 51-60
    • Maiese, K.1    Chong, Z.Z.2    Shang, Y.C.3    Wang, S.4
  • 22
    • 84868592137 scopus 로고    scopus 로고
    • Impaired autophagy in neurons after disinhibition of mammalian target of rapamycin and its contribution to epileptogenesis
    • PMID:23136410
    • McMahon, J., Huang, X., Yang, J., Komatsu, M., Yue, Z., Qian, J., et al. 2012. Impaired autophagy in neurons after disinhibition of mammalian target of rapamycin and its contribution to epileptogenesis. J. Neurosci. 32(45): 15704-15714. doi:10.1523/JNEUROSCI.2392-12.2012. PMID:23136410.
    • (2012) J. Neurosci , vol.32 , Issue.45 , pp. 15704-15714
    • McMahon, J.1    Huang, X.2    Yang, J.3    Komatsu, M.4    Yue, Z.5    Qian, J.6
  • 23
    • 35348895508 scopus 로고    scopus 로고
    • Bcl-w protects hippocampus during experimental status epilepticus
    • PMID:17702891
    • Murphy, B., Dunleavy, M., Shinoda, S., Schindler, C., Meller, R., Bellver-Estelles, C., et al. 2007. Bcl-w protects hippocampus during experimental status epilepticus. Am. J. Pathol. 171(4): 1258-1268. doi:10.2353/ajpath.2007.070269. PMID:17702891.
    • (2007) Am. J. Pathol , vol.171 , Issue.4 , pp. 1258-1268
    • Murphy, B.1    Dunleavy, M.2    Shinoda, S.3    Schindler, C.4    Meller, R.5    Bellver-Estelles, C.6
  • 24
    • 84903467736 scopus 로고    scopus 로고
    • Ars Moriendi; the art of dying well — new insights into the molecular pathways of necroptotic cell death
    • PMID:24469330
    • Murphy, J.M., and Silke, J. 2014. Ars Moriendi; the art of dying well — new insights into the molecular pathways of necroptotic cell death. EMBO Rep. 15(2): 155-164. doi:10.1002/embr.201337970. PMID:24469330.
    • (2014) EMBO Rep , vol.15 , Issue.2 , pp. 155-164
    • Murphy, J.M.1    Silke, J.2
  • 26
    • 79958768725 scopus 로고    scopus 로고
    • Impaired autophagy: A link between neurodegenerative diseases and progressive myoclonus epilepsies
    • PMID:21482188
    • Polajnar, M., and Zerovnik, E. 2011. Impaired autophagy: a link between neurodegenerative diseases and progressive myoclonus epilepsies. Trends Mol. Med. 17(6): 293-300. doi:10.1016/j.molmed.2011.02.005. PMID:21482188.
    • (2011) Trends Mol. Med , vol.17 , Issue.6 , pp. 293-300
    • Polajnar, M.1    Zerovnik, E.2
  • 27
    • 78649240333 scopus 로고    scopus 로고
    • Laforin in autophagy: A possible link between carbohydrate and protein in Lafora disease?
    • PMID:20818153
    • Puri, R., and Ganesh, S. 2010. Laforin in autophagy: a possible link between carbohydrate and protein in Lafora disease? Autophagy, 6(8): 1229-1231. doi: 10.4161/auto.6.8.13307. PMID:20818153.
    • (2010) Autophagy , vol.6 , Issue.8 , pp. 1229-1231
    • Puri, R.1    Ganesh, S.2
  • 28
    • 84857322931 scopus 로고    scopus 로고
    • Autophagy defects in Lafora disease: Cause or consequence?
    • PMID: 22301990
    • Puri, R., and Ganesh, S. 2012. Autophagy defects in Lafora disease: cause or consequence? Autophagy, 8(2): 289-290. doi:10.4161/auto.8.2.19010. PMID: 22301990.
    • (2012) Autophagy , vol.8 , Issue.2 , pp. 289-290
    • Puri, R.1    Ganesh, S.2
  • 29
    • 84949223212 scopus 로고    scopus 로고
    • Curcumin hormesis mediates a cross-talk between autophagy and cell death
    • PMID:26633709
    • Rainey, N., Motte, L., Aggarwal, B.B., and Petit, P.X. 2015. Curcumin hormesis mediates a cross-talk between autophagy and cell death. Cell Death Dis. 6: e2003. doi:10.1038/cddis.2015.343. PMID:26633709.
    • (2015) Cell Death Dis , vol.6
    • Rainey, N.1    Motte, L.2    Aggarwal, B.B.3    Petit, P.X.4
  • 30
    • 84951757609 scopus 로고    scopus 로고
    • Curcumin induces apoptosis by inhibiting sarco/endoplasmic reticulum Ca(2+) ATPase activity in ovarian cancer cells
    • PMID:26607901
    • Seo, J.A., Kim, B., Dhanasekaran, D.N., Tsang, B.K., and Song, Y.S. 2016. Curcumin induces apoptosis by inhibiting sarco/endoplasmic reticulum Ca(2+) ATPase activity in ovarian cancer cells. Cancer Lett. 371(1): 30-37. doi:10.1016/j.canlet. 2015.11.021. PMID:26607901.
    • (2016) Cancer Lett , vol.371 , Issue.1 , pp. 30-37
    • Seo, J.A.1    Kim, B.2    Dhanasekaran, D.N.3    Tsang, B.K.4    Song, Y.S.5
  • 31
    • 84899850247 scopus 로고    scopus 로고
    • Ischemic insults induce necroptotic cell death in hippocampal neurons through the up-regulation of endogenous RIP3
    • PMID:24746856
    • Vieira, M., Fernandes, J., Carreto, L., Anuncibay-Soto, B., Santos, M., Han, J., et al. 2014. Ischemic insults induce necroptotic cell death in hippocampal neurons through the up-regulation of endogenous RIP3. Neurobiol. Dis. 68: 26-36. doi:10.1016/j.nbd.2014.04.002. PMID:24746856.
    • (2014) Neurobiol. Dis , vol.68 , pp. 26-36
    • Vieira, M.1    Fernandes, J.2    Carreto, L.3    Anuncibay-Soto, B.4    Santos, M.5    Han, J.6
  • 32
    • 84861195802 scopus 로고    scopus 로고
    • Necroptosis: An emerging form of programmed cell death
    • PMID:21962882
    • Wu, W., Liu, P., and Li, J. 2012. Necroptosis: an emerging form of programmed cell death. Crit. Rev. Oncol./Hematol. 82(3): 249-258. doi:10.1016/j.critrevonc. 2011.08.004. PMID:21962882.
    • (2012) Crit. Rev. Oncol./Hematol. , vol.82 , Issue.3 , pp. 249-258
    • Wu, W.1    Liu, P.2    Li, J.3
  • 33
    • 84888605951 scopus 로고    scopus 로고
    • Curcumin induces autophagy via activating the AMPK signaling pathway in lung adenocarcinoma cells
    • PMID: 24048094
    • Xiao, K., Jiang, J., Guan, C., Dong, C., Wang, G., Bai, L., et al. 2013. Curcumin induces autophagy via activating the AMPK signaling pathway in lung adenocarcinoma cells. J. Pharmacol. Sci. 123(2): 102-109. doi:10.1254/jphs.13085FP. PMID: 24048094.
    • (2013) J. Pharmacol. Sci , vol.123 , Issue.2 , pp. 102-109
    • Xiao, K.1    Jiang, J.2    Guan, C.3    Dong, C.4    Wang, G.5    Bai, L.6
  • 34
    • 80052502402 scopus 로고    scopus 로고
    • Death and survival of neuronal and astrocytic cells in ischemic brain injury: A role of autophagy
    • PMID:21804578
    • Xu, M., and Zhang, H.L. 2011. Death and survival of neuronal and astrocytic cells in ischemic brain injury: a role of autophagy. Acta Pharmacol. Sin. 32(9): 1089-1099. doi:10.1038/aps.2011.50. PMID:21804578.
    • (2011) Acta Pharmacol. Sin , vol.32 , Issue.9 , pp. 1089-1099
    • Xu, M.1    Zhang, H.L.2
  • 35
    • 79551618617 scopus 로고    scopus 로고
    • The targets of curcumin
    • PMID:20955148
    • Zhou, H., Beevers, C.S., and Huang, S. 2011. The targets of curcumin. Curr. Drug Targets, 12(3): 332-347. doi:10.2174/138945011794815356. PMID:20955148.
    • (2011) Curr. Drug Targets , vol.12 , Issue.3 , pp. 332-347
    • Zhou, H.1    Beevers, C.S.2    Huang, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.