Relationship between normal tension glaucoma and Flammer syndrome

EPMA Journal

Volumn 8, Issue 2, 2017, Pages 111-117

  Konieczka, Katarzyna ^a   Choi, Hyuk Jin ^b   Koch, Simone ^a   Fankhauser, Franz ^c,d   Schoetzau, Andreas ^a   Kim, Dong Myung ^e  

^a UNIVERSITY OF BASEL   (Switzerland)

^b Seoul National University College of Medicine   (South Korea)

^c Augenzentrum Fankhauser AG   (Switzerland)

^d VICTOR BABES UNIVERSITY OF MEDICINE AND PHARMACY   (Romania)

^e Seoul National University Hospital   (South Korea)

Author keywords

Flammer syndrome; Glaucomatous optic neuropathy; Normal tension glaucoma; Ocular blood flow; Prediction of health problems; Predictive, preventive, personalized medicine; Primary vascular dysregulation

Indexed keywords

ADULT; ARTICLE; BLOOD PRESSURE; BODY WEIGHT; COLD SENSATION; CONTROLLED STUDY; DISEASE ASSOCIATION; DIZZINESS; DRUG SENSITIVITY; FEMALE; FLAMMER SYNDROME; FOOT; HAND; HEADACHE; HUMAN; LOW TENSION GLAUCOMA; MAJOR CLINICAL STUDY; MALE; MIGRAINE; NOCICEPTION; PERFECTIONISM; PRIORITY JOURNAL; QUESTIONNAIRE; SKIN; SLEEP; SLEEP ONSET; SMELLING; SOUTH KOREAN; SYMPTOM; SYNDROME; THIRST; TINNITUS; VASCULAR DISEASE;

EID: 85020720784     PISSN: 18785077     EISSN: 18785085     Source Type: Journal    
DOI: 10.1007/s13167-017-0097-3     Document Type: Article

References (57)

1. Flammer J, Orgul S, Costa VP, Orzalesi N, Krieglstein GK, Serra LM, et al. The impact of ocular blood flow in glaucoma. Prog Retin Eye Res. 2002;21:359-93.
2. Nakazawa T. Ocular blood flow and influencing factors for glaucoma. Asia Pac J Ophthalmol (Phila). 2016;5:38-44.
3. Kaiser HJ, Schoetzau A, Flammer J. Blood flow velocity in the extraocular vessels in chronic smokers. Br J Ophthalmol. 1997;81:133-5.
4. Shiga Y, Kunikata H, Aizawa N, Kiyota N, Maiya Y, Yokoyama Y, et al. Optic nerve head blood flow, as measured by laser speckle flowgraphy, is significantly reduced in preperimetric glaucoma. Curr eye res. 2016;41:1447-53.
5. Wang X, Jiang C, Ko T, Kong X, Yu X, Min W, et al. Correlation between optic disc perfusion and glaucomatous severity in patients with open-angle glaucoma: an optical coherence tomography angiography study. Graefes Arch Clin Exp Ophthalmol. 2015;253:1557-64.
6. Moore NA, Harris A, Wentz S, Verticchio Vercellin AC, Parekh P, Gross J, et al. Baseline retrobulbar blood flow is associated with both functional and structural glaucomatous progression after 4 years. Br J Ophthalmol. 2016.
7. Gasser P, Flammer J. Blood-cell velocity in the nailfold capillaries of patients with normal-tension and high-tension glaucoma. Am J Ophthalmol. 1991;111:585-8.
8. Kaiser HJ, Flammer J. Systemic hypotension: a risk factor for glaucomatous damage? Ophthalmologica. 1991;203:105-8.
9. Gasser P, Flammer J. Influence of vasospasm on visual function. Doc Ophthalmol. 1987;66:3-18.
10. Li S, Zhang A, Cao W, Sun X. Elevated plasma endothelin-1 levels in normal tension glaucoma and primary open-angle glaucoma: a meta-analysis. J Ophthalmol. 2016;2016:2678017.
11. Flammer J, Konieczka K, Flammer AJ. The primary vascular dysregulation syndrome: implications for eye diseases. EPMA j. 2013;4:14.
12. Flammer J, Konieczka K, Bruno RM, Virdis A, Flammer AJ, Taddei S. The eye and the heart. Eur Heart J. 2013;34:1270-8.
13. Konieczka K, Ritch R, Traverso CE, Kim DM, Kook MS, Gallino A, et al. Flammer syndrome. EPMA j. 2014;5:11.
14. Konieczka K, Gugleta K. Glaukom (4.,A). Hans Huber Bern. 2015.
15. Konieczka K, Flammer J. Phenomenology and clinical relevance of the Flammer syndrome. Klin Monatsbl Augenheilkd. 2016;233:1331-6.
16. Konieczka K. Flammer Syndrom. In: Brähler E, Hoefert H-W, editors. Lexikon der Modernen Krankheiten. Berlin. Deutschland: Medizinisch Wissenschaftliche Verlagsgesellschaft; 2014.
17. Konieczka K, Flammer J. Glaukom [Le glaucome]. Swiss Medical Forum. 2017:105-112.
18. Guthauser U, Flammer J, Mahler F. The relationship between digital and ocular vasospasm. Graefes Arch Clin Exp Ophthalmol. 1988;226:224-6.
19. Teuchner B, Orgul S, Ulmer H, Haufschild T, Flammer J. Reduced thirst in patients with a vasospastic syndrome. Acta Ophthalmol Scand. 2004;82:738-40.
20. Gherghel D, Orgul S, Gugleta K, Flammer J. Retrobulbar blood flow in glaucoma patients with nocturnal over-dipping in systemic blood pressure. Am J Ophthalmol. 2001;132:641-7.
21. Flammer J. Glaucoma. 3rd ed. Hogrefe & Huber: Bern; 2006.
22. Wunderlich K, Zimmerman C, Gutmann H, Teuchner B, Flammer J, Drewe J. Vasospastic persons exhibit differential expression of ABC-transport proteins. Mol Vis. 2003;9:756-61.
23. Gasser P, Meienberg O. Finger microcirculation in classical migraine. A video-microscopic study of nailfold capillaries. Eur Neurol. 1991;31:168-71.
24. Palmer KT, Griffin MJ, Syddall HE, Pannett B, Cooper C, Coggon D. Raynaud's phenomenon, vibration induced white finger, and difficulties in hearing. Occup Environ med. 2002;59:640-2.
25. Mozaffarieh M, Fontana Gasio P, Schotzau A, Orgul S, Flammer J, Krauchi K. Thermal discomfort with cold extremities in relation to age, gender, and body mass index in a random sample of a Swiss urban population. Popul Health Metr. 2010;8:17.
26. Gasser P, Stumpfig D, Schotzau A, Ackermann-Liebrich U, Flammer J. Body mass index in glaucoma. J Glaucoma. 1999;8:8-11.
27. Krauchi K, Deboer T. The interrelationship between sleep regulation and thermoregulation. Front Biosci (Landmark Ed). 2010;15:604-25.
28. Pache M, Krauchi K, Cajochen C, Wirz-Justice A, Dubler B, Flammer J, et al. Cold feet and prolonged sleep-onset latency in vasospastic syndrome. Lancet. 2001;358:125-6.
29. Mozaffarieh M, Hauenstein D, Schoetzau A, Konieczka K, Flammer J. Smell perception in normal tension glaucoma patients. Mol Vis. 2010;16:506-10.
30. Pache M, Ochs J, Genth E, Mierau R, Kube T, Flammer J. Increased plasma endothelin-1 levels in fibromyalgia syndrome. Rheumatology (Oxford). 2003;42:493-4.
31. Konieczka K, Choi HJ, Koch S, Schoetzau A, Kuenzi D, Kim DM. Frequency of symptoms and signs of primary vascular dysregulation in Swiss and Korean populations. Klin Monatsbl Augenheilkd. 2014;231:344-7.
32. TeamRDC. R: A language and environment for statistical computing. Vienna, Austria: R Foundation for Statistical Computing. 2012.
33. Hirooka K, Shiraga F, Hasegawa E. Bradykinin sensitivity in primary open-angle glaucoma and normal-tension glaucoma patients. Am J Ophthalmol. 2002;134:922-4.
34. Konieczka K, Koch S, Binggeli T, Schoetzau A, Kesselring J. Multiple sclerosis and primary vascular dysregulation (Flammer syndrome). EPMA j. 2016;7:13.
35. Pirodda A, Brandolini C, Cassandro E, Borghi C. Primary vascular dysregulation syndrome: possible implications for inner ear acute diseases? Med Hypotheses. 2015;85:586-7.
36. Phelps CD, Corbett JJ. Migraine and low-tension glaucoma. A case-control study. Invest Ophthalmol Vis Sci. 1985;26:1105-8.
37. Drance S, Anderson DR, Schulzer M, Collaborative Normal-Tension Glaucoma Study G. Risk factors for progression of visual field abnormalities in normal-tension glaucoma. Am J Ophthalmol. 2001;131:699-708.
38. Flammer J, Guthauser U, Mahler F. Do ocular vasospasms help cause low-tension glaucoma? Doc Ophthalmol Proc Series. 1987;49:397-9.
39. Kaiser HJ, Flammer J, Graf T, Stumpfig D. Systemic blood pressure in glaucoma patients. Graefes Arch Clin Exp Ophthalmol. 1993;231:677-80.
40. Joe SG, Choi J, Sung KR, Park SB, Kook MS. Twenty-four hour blood pressure pattern in patients with normal tension glaucoma in the habitual position. Korean J Ophthalmol. 2009;23:32-9.
41. Konieczka K, Koch S, Schoetzau A, Todorova MG. Increased prevalence of Flammer syndrome in patients with retinitis pigmentosa. Klin Monatsbl Augenheilkd. 2016;233:448-52.
42. Todorova MG, Josifova T, Konieczka K. Endothelin-1 plasma levels in patients with both retinitis pigmentosa and Flammer syndrome. Klin Monatsbl Augenheilkd. 2015;232:514-8.
43. Konieczka K, Flammer AJ, Todorova M, Meyer P, Flammer J. Retinitis pigmentosa and ocular blood flow. EPMA J. 2012;3:17.
44. Konieczka K, Flammer J, Sternbuch J, Binggeli T, Fraenkl S. Leber's Hereditary Optic Neuropathy, Normal Tension Glaucoma, and Flammer Syndrome: Long Term Follow-up of a Patient. Klin Monbl Augenheilkd. 2017.
45. Konieczka K, Todorova MG, Bojinova RI, Binggeli T, Chackathayil TN, Flammer J. Unexpected effect of calcium channel blockers on the optic nerve compartment syndrome. Klin Monatsbl Augenheilkd. 2016;233:387-90.
46. Killer HE. Compartment syndromes of the optic nerve and open-angle glaucoma. J Glaucoma. 2013;22(Suppl 5):S19-20.
47. Fraenkl SA, Mozaffarieh M, Flammer J. Retinal vein occlusions: the potential impact of a dysregulation of the retinal veins. EPMA j. 2010;1:253-61.
48. Flammer J, Konieczka K. Retinal venous pressure: the role of endothelin. EPMA j. 2015;6:21.
49. Konieczka K, Todorova MG, Chackathayil TN, Henrich PB. Cilioretinal artery occlusion in a young patient with flammer syndrome and increased retinal venous pressure. Klin Monatsbl Augenheilkd. 2015;232:576-8.
50. Terelak-Borys B, Grabska-Liberek I, Piekarniak-Wozniak A, Konieczka K. Choroidal infarction in a glaucoma patient with Flammer syndrome: a case report with a long term follow-up. BMC Ophthalmol. 2017;17:23.
51. Bojinova RI, Konieczka K, Meyer P, Todorova MG. The trilateral link between anaesthesia, perioperative visual loss and Flammer syndrome. BMC Anesthesiol. 2016;16:10.
52. Bojinova RI, Konieczka K, Todorova MG. Unilateral loss of vision after spinal surgery in a patient with Flammer syndrome. Klin Monatsbl Augenheilkd. 2016;233:429-31.
53. Golubnitschaja O, Debald M, Yeghiazaryan K, Kuhn W, Pesta M, Costigliola V, et al. Breast cancer epidemic in the early twenty-first century: evaluation of risk factors, cumulative questionnaires and recommendations for preventive measures. Tumour Biol. 2016.
54. Yeghiazaryan K, Flammer J, Orgul S, Wunderlich K, Golubnitschaja O. Vasospastic individuals demonstrate significant similarity to glaucoma patients as revealed by gene expression profiling in circulating leukocytes. Mol Vis. 2009;15:2339-48.
55. Moenkemann H, Flammer J, Wunderlich K, Breipohl W, Schild HH, Golubnitschaja O. Increased DNA breaks and up-regulation of both G(1) and G(2) checkpoint genes p21(WAF1/CIP1) and 14-3-3 sigma in circulating leukocytes of glaucoma patients and vasospastic individuals. Amino Acids. 2005;28:199-205.
56. Golubnitschaja O, Flammer J. What are the biomarkers for glaucoma? Surv Ophthalmol. 2007;52(Suppl 2):S155-61.
57. Golubnitschaja O, Yeghiazaryan K, Flammer J. Key molecular pathways affected by glaucoma pathology: is predictive diagnosis possible? EPMA j. 2010;1:237-44.