Simultaneous UHPLC-UV analysis of hydroxychloroquine, minocycline and doxycycline from serum samples for the therapeutic drug monitoring of Q fever and Whipple's disease

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 1060, Issue , 2017, Pages 166-172

  Armstrong, Nicholas ^a   Richez, Magali ^a   Raoult, Didier ^a   Chabriere, Eric ^a  

^a IHU MÉDITERRANÉE INFECTION   (France)

Author keywords

Doxycycline; Hydroxychloroquine; Minocycline; Q fever; UHPLC; UV; Whipple's disease

Indexed keywords

CALIBRATION; DRUG PRODUCTS; PATIENT MONITORING;

DOXYCYCLINE; HYDROXYCHLOROQUINE; MINOCYCLINE; Q FEVER; UHPLC;

BODY FLUIDS;

CHLORAMPHENICOL; DOXYCYCLINE; DOXYCYCLINE HYCLATE; HYDROXYCHLOROQUINE; IMIPENEM; MINOCYCLINE; OXYTETRACYCLINE; RIFAMPICIN; STREPTOMYCIN; ANTIINFECTIVE AGENT;

ARTICLE; CONTROLLED STUDY; DRUG MONITORING; EUROPEAN MEDICINES AGENCY; HUMAN; INTESTINE LIPODYSTROPHY; LIQUID LIQUID EXTRACTION; PRACTICE GUIDELINE; PRIORITY JOURNAL; Q FEVER; QUALITY CONTROL; RETENTION TIME; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; ULTRAVIOLET RADIATION; BLOOD; CHEMISTRY; DRUG STABILITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIMIT OF DETECTION; PROCEDURES; REPRODUCIBILITY; STATISTICAL MODEL; WHIPPLE DISEASE;

ANTI-BACTERIAL AGENTS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DOXYCYCLINE; DRUG MONITORING; DRUG STABILITY; HUMANS; HYDROXYCHLOROQUINE; LIMIT OF DETECTION; LINEAR MODELS; MINOCYCLINE; Q FEVER; REPRODUCIBILITY OF RESULTS; WHIPPLE DISEASE;

EID: 85020718495     PISSN: 15700232     EISSN: 1873376X     Source Type: Journal    
DOI: 10.1016/j.jchromb.2017.06.011     Document Type: Article

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