The biology of free guanidine as revealed by riboswitches

Biochemistry

Volumn 56, Issue 2, 2017, Pages 345-347

  Breaker, Ronald R ^a   Atilho, Ruben M ^a   Malkowski, Sarah N ^a   Nelson, James W ^a,b   Sherlock, Madeline E ^a  

^a YALE UNIVERSITY   (United States)

^b HARVARD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMMONIA; ANTIBIOTIC AGENT; APTAMER; ARGININE; CARBON DIOXIDE; CARBOXYLIC ACID; CARBOXYLYASE; CREATINE; GUANIDINE; GUANINE; NITROGEN; S ADENOSYLMETHIONINE; UNTRANSLATED RNA;

BIOCHEMISTRY; BIOINFORMATICS; BIOLOGY; BIOREMEDIATION; CELL METABOLISM; COMPLEX FORMATION; DENATURATION; DNA HAIRPIN; DRUG TARGETING; DRUG TRANSPORT; ENERGY RESOURCE; EVALUATION STUDY; EVIDENCE BASED PRACTICE; FERMENTATION TECHNIQUE; GENE CONTROL; GENE EXPRESSION; GENE FUNCTION; GENE PRODUCT; GENETIC ASSOCIATION; GLUCOSE INTAKE; HYDROGEN BOND; LIGAND BINDING; NOTE; PRIORITY JOURNAL; RIBOSWITCH; RNA-BINDING DOMAIN; SCIENTIFIC LITERATURE; X RAY; CHEMISTRY; CONFORMATION; GENETICS; METABOLISM; MOLECULAR MODEL; NUCLEOTIDE SEQUENCE;

APTAMERS, NUCLEOTIDE; BASE SEQUENCE; GUANIDINE; MODELS, MOLECULAR; NUCLEIC ACID CONFORMATION; RIBOSWITCH; RNA, UNTRANSLATED;

EID: 85020681585     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/acs.biochem.6b01269     Document Type: Note

References (5)

1. Nelson, J. W., Atilho, R. M., Sherlock, M. E., Stockbridge, R. B., and Breaker, R. R. (2017) Metabolism of free guanidine in bacteria is regulated by a widespread riboswitch class. Mol. Cell, DOI: 10.1016/j.molcel.2016.11.019.
2. Sherlock, M. E., Malkowski, S. N., and Breaker, R. R. (2017) Biochemical validation of a second guanidine riboswitch class in bacteria. Biochemistry, DOI: 10.1021/acs.biochem.6b01270.
3. Sherlock, M. E., and Breaker, R. R. (2017) Biochemical validation of a third guanidine riboswitch class in bacteria. Biochemistry, DOI: 10.1021/acs.biochem.6b01271.
4. Barrick, J. E., Corbino, K. A., Winkler, W. C., Nahvi, A., Mandal, M., Collins, J., Lee, M., Roth, A., Sudarsan, N., Jona, I., Wickiser, J. K., and Breaker, R. R. (2004) New RNA motifs suggest an expanded scope for riboswitches in bacterial genetic control. Proc. Natl. Acad. Sci. U. S. A. 101(17), 6421-6426.
5. Reiss, C. W., Xiong, Y., and Strobel, S. A. (2017) Structural basis for guanidine sensing by the ykkC family of riboswitches. Structure, DOI: 10.1016/j.str.2016.11.020.