Maturation of secreted HCV particles by incorporation of secreted ApoE protects from antibodies by enhancing infectivity

Journal of Hepatology

Volumn 67, Issue 3, 2017, Pages 480-489

  Bankwitz, Dorothea ^a   Doepke, Mandy ^a   Hueging, Kathrin ^a   Weller, Romy ^a   Bruening, Janina ^a   Behrendt, Patrick ^a,c   Lee, Ji Young ^b   Vondran, Florian W R ^c,d   Manns, Michael P ^c,d   Bartenschlager, Ralf ^b,e   Pietschmann, Thomas ^a,d  

^a INSTITUTE OF INFECTION IMMUNOLOGY   (Germany)

^b UNIVERSITY OF HEIDELBERG   (Germany)

^c HANNOVER MEDICAL SCHOOL   (Germany)

^d German Centre for Infection Research (DZIF) Partner Site Hannover Braunschweig   (Germany)

^e GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

Antibody escape; Apolipoprotein E; Assembly; Entry; Hepatitis C virus; Neutralizing antibody

Indexed keywords

APOLIPOPROTEIN E; CORE PROTEIN; GLYCOPROTEIN E1; GLYCOPROTEIN E2; IODIXANOL; MONOCLONAL ANTIBODY; NEUTRALIZING ANTIBODY; PROTEOHEPARAN SULFATE; SCAVENGER RECEPTOR BI; SHORT HAIRPIN RNA; VIRUS ANTIBODY; HEPARIN; HEPARIN PROTEOGLYCAN; PROTEOGLYCAN;

ANTIBODY COMBINING SITE; ANTIGEN BINDING; ANTIVIRAL ACTIVITY; ARTICLE; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; HEPATITIS C; HEPATITIS C VIRUS; HEPATOCELLULAR CARCINOMA CELL LINE; HEPATOMA CELL; HUMAN; HUMAN CELL; IMMUNE EVASION; IMMUNOPRECIPITATION; IN VITRO STUDY; LIVER CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPLETION; VIRION; VIRUS ATTACHMENT; VIRUS CORE; VIRUS ENTRY; VIRUS NEUTRALIZATION; VIRUS PARTICLE; VIRUS RESISTANCE; VIRUS TRANSMISSION; ANALOGS AND DERIVATIVES; BLOOD; HEPACIVIRUS; IMMUNOLOGY; PATHOGENICITY; PHYSIOLOGY; TUMOR CELL LINE;

ANTIBODIES, NEUTRALIZING; APOLIPOPROTEINS E; CELL LINE, TUMOR; HEPACIVIRUS; HEPARIN; HUMANS; PROTEOGLYCANS; VIRION;

EID: 85020642109     PISSN: 01688278     EISSN: 16000641     Source Type: Journal    
DOI: 10.1016/j.jhep.2017.04.010     Document Type: Article

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