Fetal origins of adult cardiac disease: A novel approach to prevent fetal growth restriction induced cardiac dysfunction using insulin like growth factor

Pediatric Research

Volumn 81, Issue 6, 2017, Pages 919-925

  Alsaied, Tarek ^a   Omar, Khaled ^b   James, Jeanne F ^a   Hinton, Robert B ^a   Crombleholme, Timothy M ^b   Habli, Mounira ^a  

^a CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^b CHILDREN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

SOMATOMEDIN C;

ANIMAL EXPERIMENT; ANIMAL MODEL; BIRTH WEIGHT; CARDIOVASCULAR DISEASE; COMPARATIVE STUDY; CONFERENCE PAPER; CONTROLLED STUDY; DOPPLER ECHOCARDIOGRAPHY; ECHOCARDIOGRAPH; FEMALE; GENE TRANSFER; HEART FUNCTION; INTRAUTERINE GROWTH RETARDATION; LAPAROTOMY; LONG TERM SURVIVAL; M MODE ECHOCARDIOGRAPHY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROPHYLAXIS; SEX DIFFERENCE; TRANSTHORACIC ECHOCARDIOGRAPHY; ANIMAL; C57BL MOUSE; GENETICS; HEART DISEASE; PATHOPHYSIOLOGY; PREGNANCY; SEXUAL CHARACTERISTICS;

ANIMALS; FEMALE; FETAL GROWTH RETARDATION; HEART DISEASES; INSULIN-LIKE GROWTH FACTOR I; MALE; MICE; MICE, INBRED C57BL; PREGNANCY; SEX CHARACTERISTICS;

EID: 85020469339     PISSN: 00313998     EISSN: 15300447     Source Type: Journal    
DOI: 10.1038/pr.2017.18     Document Type: Conference Paper

References (44)

1. Spence D, Stewart MC, Alderdice FA, Patterson CC, Halliday HL. Intrauterine growth restriction and increased risk of hypertension in adult life: a follow-up study of 50-year-olds. Public Health 2012;126:561-5.
2. Hochberg Z, Feil R, Constancia M, et al. Child health, developmental plasticity, and epigenetic programming. Endocr Rev 2011;32:159-224.
3. Barker DJ, Osmond C, Golding J, Kuh D, Wadsworth ME. Growth in utero, blood pressure in childhood and adult life, and mortality from cardiovascular disease. BMJ 1989;298:564-7.
4. Barker DJ, Osmond C, Law CM. The intrauterine and early postnatal origins of cardiovascular disease and chronic bronchitis. J Epidemiol Community Health 1989;43:237-40.
5. Gluckman PD, Hanson MA, Cooper C, Thornburg KL. Effect of in utero and early-life conditions on adult health and disease. N Engl J Med 2008;359:61-73.
6. Altin H, Karaarslan S, Karataş Z, Alp H, Şap F, Baysal T. Evaluation of cardiac functions in term small for gestational age newborns with mild growth retardation: a serial conventional and tissue Doppler imaging echocardiographic study. Early Hum Dev 2012;88:757-64.
7. Crispi F, Bijnens B, Figueras F, et al. Fetal growth restriction results in remodeled and less efficient hearts in children. Circulation 2010;121:2427-36.
8. Sehgal A, Doctor T, Menahem S. Cardiac function and arterial biophysical properties in small for gestational age infants: postnatal manifestations of fetal programming. J Pediatr 2013;163:1296-300.
9. Wright EC, Fain PR, Barker DF, Chao MV. Two polymorphic TaqI sites at the human NGFR locus (17q12 - 17q22). Nucleic Acids Res 1989;17:824.
10. Santos MS, Joles JA. Early determinants of cardiovascular disease. Best Pract Res Clin Endocrinol Metab 2012;26:581-97.
11. Habli M, Jones H, Aronow B, Omar K, Crombleholme TM. Recapitulation of characteristics of human placental vascular insufficiency in a novel mouse model. Placenta 2013;34:1150-8.
12. Tintu A, Rouwet E, Verlohren S, et al. Hypoxia induces dilated cardiomyopathy in the chick embryo: mechanism, intervention, and long-term consequences. PLoS One 2009;4:e5155.
13. Schwarz ER, Pollick C, Meehan WP, Kloner RA. Evaluation of cardiac structures and function in small experimental animals: transthoracic, transesophageal, and intraventricular echocardiography to assess contractile function in rat heart. Basic Res Cardiol 1998;93:477-86.
14. Lim K, Lombardo P, Schneider-Kolsky M, Black MJ. Intrauterine growth restriction coupled with hyperglycemia: effects on cardiac structure in adult rats. Pediatr Res 2012;72:344-51.
15. Puche JE, Castilla-Cortázar I. Human conditions of insulin-like growth factor-I (IGF-I) deficiency. J Transl Med 2012;10:224.
16. Ren J, Samson WK, Sowers JR. Insulin-like growth factor I as a cardiac hormone: physiological and pathophysiological implications in heart disease. J Mol Cell Cardiol 1999;31:2049-61.
17. McMullen MR, Pritchard MT, Nagy LE. Isolation of Kupffer cells from rats fed chronic ethanol. Methods Mol Biol 2008;447:199-212.
18. Koudstaal S, Bastings MM, Feyen DA, et al. Sustained delivery of insulin-like growth factor-1/hepatocyte growth factor stimulates endogenous cardiac repair in the chronic infarcted pig heart. J Cardiovasc Transl Res 2014;7:232-41.
19. Ellison GM, Torella D, Dellegrottaglie S, et al. Endogenous cardiac stem cell activation by insulin-like growth factor-1/hepatocyte growth factor intracoronary injection fosters survival and regeneration of the infarcted pig heart. J Am Coll Cardiol 2011;58:977-86.
20. Katz AB, Keswani SG, Habli M, et al. Placental gene transfer: transgene screening in mice for trophic effects on the placenta. Am J Obstet Gynecol 2009;201:499.e1-8.
21. Bauer MK, Breier BB, Bloomfield FH, Jensen EC, Gluckman PD, Harding JE. Chronic pulsatile infusion of growth hormone to growth-restricted fetal sheep increases circulating fetal insulin-like growth factor-I levels but not fetal growth. J Endocrinol 2003;177:83-92.
22. Eremia SC, de Boo HA, Bloomfield FH, Oliver MH, Harding JE. Fetal and amniotic insulin-like growth factor-I supplements improve growth rate in intrauterine growth restriction fetal sheep. Endocrinology 2007;148:2963-72.
23. Wali JA, de Boo HA, Derraik JG, et al. Weekly intra-amniotic IGF-1 treatment increases growth of growth-restricted ovine fetuses and up-regulates placental amino acid transporters. PLoS One 2012;7:e37899.
24. Cox B, Kotlyar M, Evangelou AI, et al. Comparative systems biology of human and mouse as a tool to guide the modeling of human placental pathology. Mol Syst Biol 2009;5:279.
25. Gruss CJ, Satyamoorthy K, Berking C, et al. Stroma formation and angiogenesis by overexpression of growth factors, cytokines, and proteolytic enzymes in human skin grafted to SCID mice. J Invest Dermatol 2003;120:683-92.
26. Hinton RB Jr, Alfieri CM, Witt SA, et al. Mouse heart valve structure and function: echocardiographic and morphometric analyses from the fetus through the aged adult. Am J Physiol Heart Circ Physiol 2008;294:H2480-8.
27. Acehan D, Malhotra A, Xu Y, Ren M, Stokes DL, Schlame M. Cardiolipin affects the supramolecular organization of ATP synthase in mitochondria. Biophys J 2011;100:2184-92.
28. Rodrigues AC, Hataishi R, Ichinose F, et al. Relationship of systolic dysfunction to area at risk and infarction size after ischemia-reperfusion in mice. J Am Soc Echocardiogr 2004;17:948-53.
29. Yoon PW, Bastian B, Anderson RN, Collins JL, Jaffe HW; Centers for Disease Control and Prevention (CDC). Potentially preventable deaths from the five leading causes of death-United States, 2008-2010. MMWR Morb Mortal Wkly Rep 2014;63:369-74.
30. Demicheva E, Crispi F. Long-term follow-up of intrauterine growth restriction: cardiovascular disorders. Fetal Diagn Ther 2014;36:143-53.
31. Ozanne SE, Lewis R, Jennings BJ, Hales CN. Early programming of weight gain in mice prevents the induction of obesity by a highly palatable diet. Clin Sci (Lond) 2004;106:141-5.
32. Zambrano E, Bautista CJ, Deás M, et al. A low maternal protein diet during pregnancy and lactation has sex-and window of exposure-specific effects on offspring growth and food intake, glucose metabolism and serum leptin in the rat. J Physiol 2006;571(Pt 1):221-30.
33. Barker DJ, Osmond C, Forsén TJ, Kajantie E, Eriksson JG. Trajectories of growth among children who have coronary events as adults. N Engl J Med 2005;353:1802-9.
34. Barker DJ, Gelow J, Thornburg K, Osmond C, Kajantie E, Eriksson JG. The early origins of chronic heart failure: impaired placental growth and initiation of insulin resistance in childhood. Eur J Heart Fail 2010;12: 819-25.
35. Menendez-Castro C, Toka O, Fahlbusch F, et al. Impaired myocardial performance in a normotensive rat model of intrauterine growth restriction. Pediatr Res 2014;75:697-706.
36. Bahtiyar MO, Copel JA. Cardiac changes in the intrauterine growthrestricted fetus. Semin Perinatol 2008;32:190-3.
37. Fox JG. The Mouse in Biomedical Research. Amsterdam, Boston: Elsevier, AP, 2007. pp. 2-4.
38. Eriksson JG. Early growth and coronary heart disease and type 2 diabetes: findings from the Helsinki Birth Cohort Study (HBCS). Am J Clin Nutr 2011;94(6 Suppl):1799S-802S.
39. Ma N, Hardy DB. The fetal origins of the metabolic syndrome: can we intervene? J Pregnancy 2012;2012:482690.
40. Castellano G, Affuso F, Conza PD, Fazio S. The GH/IGF-1 axis and heart failure. Curr Cardiol Rev 2009;5:203-15.
41. Reiss K, Cheng W, Ferber A, et al. Overexpression of insulin-like growth factor-1 in the heart is coupled with myocyte proliferation in transgenic mice. Proc Natl Acad Sci USA 1996;93:8630-5.
42. Touvron M, Escoubet B, Mericskay M, et al. Locally expressed IGF1 propeptide improves mouse heart function in induced dilated cardiomyopathy by blocking myocardial fibrosis and SRF-dependent CTGF induction. Dis Model Mech 2012;5:481-91.
43. Keswani SG, Balaji S, Katz AB, et al. Intraplacental gene therapy with Ad-IGF-1 corrects naturally occurring rabbit model of intrauterine growth restriction. Hum Gene Ther 2015;26:172-82.
44. Rueda-Clausen CF, Morton JS, Lopaschuk GD, Davidge ST. Long-term effects of intrauterine growth restriction on cardiac metabolism and susceptibility to ischaemia/reperfusion. Cardiovasc Res 2011;90:285-94.