Chronic disease, risk factors and disability in adults aged 50 and above living with and without HIV: findings from the Wellbeing of Older People Study in Uganda

Global Health Action

Volumn 9, Issue 1, 2016, Pages

  Mugisha, Joseph O ^a,b   Schatz, Enid J ^b   Randell, Madeleine ^c   Kuteesa, Monica ^a   Kowal, Paul ^d,e   Negin, Joel ^c   Seeley, Janet ^a,f  

^a Uganda Research Unit on AIDS   (Uganda)

^b UNIVERSITY OF MISSOURI   (United States)

^c UNIVERSITY OF SYDNEY   (Australia)

^d WORLD HEALTH ORGANIZATION   (Switzerland)

^e UNIVERSITY OF NEWCASTLE   (Australia)

^f LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

Author keywords

Africa; aging; aging disability; HIV AIDS; non communicable diseases; older adults; Uganda

Indexed keywords

AGED; AGING; CHRONIC DISEASE; COMPLICATION; CROSS-SECTIONAL STUDY; DISABLED PERSON; FEMALE; HEALTH SURVEY; HIV INFECTIONS; HUMAN; MALE; MIDDLE AGED; PREVALENCE; QUESTIONNAIRE; RISK FACTOR; SEX DIFFERENCE; SOCIOECONOMICS; STATISTICS AND NUMERICAL DATA; UGANDA; VERY ELDERLY;

AGED; AGED, 80 AND OVER; AGING; CHRONIC DISEASE; CROSS-SECTIONAL STUDIES; DISABLED PERSONS; FEMALE; HEALTH SURVEYS; HIV INFECTIONS; HUMANS; MALE; MIDDLE AGED; PREVALENCE; RISK FACTORS; SEX FACTORS; SOCIOECONOMIC FACTORS; SURVEYS AND QUESTIONNAIRES; UGANDA;

EID: 85020324442     PISSN: None     EISSN: 16549880     Source Type: Journal    
DOI: 10.3402/gha.v9.31098     Document Type: Article

References (68)

1. Anderson G, Horvath J. The growing burden of chronic disease in America. Public Health Rep. 2004; 119: 263.
2. Acosta D, Rottbeck R, Rodríguez JG, González LM, Almánzar MR, Minaya SN, etal. The prevalence and social patterning of chronic diseases among older people in a population undergoing health transition. A 10/66 Group cross-sectional population-based survey in the Dominican Republic. BMC Public Health. 2010; 10: 344.
3. Hirschhorn LR, Kaaya SF, Garrity PS, Chopyak E, Fawzi MC. Cancer and the ‘other’ noncommunicable chronic diseases in older people living with HIV/AIDS in resource-limited settings: a challenge to success. AIDS. 2012; 26: S65–75.
4. Alwan A. Global status report on noncommunicable diseases 2010. 2011; Geneva, Switzerland: World Health Organization.
5. Deepa M, Pradeepa R, Rema M, Mohan A, Deepa R, Shanthirani S, etal. The Chennai Urban Rural Epidemiology Study (CURES)-study design and methodology (urban component) (CURES-1). J Assoc Physicians India. 2003; 51: 863–70.
6. Ng N, Van Minh H, Tesfaye F, Bonita R, Byass P, Stenlund H, etal. Combining risk factors and demographic surveillance: potentials of WHO STEPS and INDEPTH methodologies for assessing epidemiological transition. Scand J Public Health. 2006; 34: 199–208.
7. Westaway MS, Maluka CS. Impact of chronic diseases on the health-related quality of life of South Africans. S Afr Med J. 2008; 94: 937.
8. Thorogood M, Connor MD, Hundt GL, Tollman SM. Understanding and managing hypertension in an African sub-district: a multidisciplinary approach1. Scand J Public Health. 2007; 35(69 suppl): 52–9.
9. Westaway MS. The impact of chronic diseases on the health and well-being of South Africans in early and later old age. Arch Gerontol Geriatr. 2010; 50: 213–21.
10. Kahn K, Garenne ML, Collinson MA, Tollman SM. Mortality trends in a new South Africa: hard to make a fresh start1. Scand J Public Health. 2007; 35(69 suppl): 26–34.
11. Negin J, Cumming R, de Ramirez SS, Abimbola S, Sachs SE. Risk factors for non-communicable diseases among older adults in rural Africa. Trop Med Int Health. 2011; 16: 640–6.
12. Negin J, Martiniuk A, Cumming RG, Naidoo N, Phaswana-Mafuya N, Madurai L, etal. Prevalence of HIV and chronic comorbidities among older adults. AIDS. 2012; 26: S55–63.
13. United Nations Population Fund (UNFPA) and HelpAge International. Ageing in the twenty-first century: A celebration and a challenge, New York: United Nations Population Fund.
14. Velkoff VA, Kowal PR. Population aging in Sub-Saharan Africa: demographic dimensions 2006. U.S.Department of Commerce, Economics and Statistics Administration. 2007; Washington DC, US: Census Bureau.
15. Pillay NK, Maharaj P. Population ageing in Africa. 2013; Aging and health in Africa. Springer. 11–51. In: Maharaj P, ed.
16. Ministry of Health, Uganda (2012). Uganda AIDS Indicator Survey 2011., Uganda: Ministry of Health.
17. Shippy RA, Karpiak SE. The aging HIV/AIDS population: fragile social networks. Aging Ment Health. 2005; 9: 246–54.
18. High KP, Brennan-Ing M, Clifford DB, Cohen MH, Currier J, Deeks SG, etal. HIV and aging: state of knowledge and areas of critical need for research. A report to the NIH Office of AIDS Research by the HIV and Aging Working Group. J Acquir Immune Defic Syndr. 2012; 60(Suppl 1): S1–18.
19. Negin J, Wariero J, Cumming RG, Mutuo P, Pronyk PM. High rates of AIDS-related mortality among older adults in rural Kenya. J Acquir Immune Defic Syndr. 2010; 55: 239–44.
20. Setel PW. Non-communicable diseases, political economy, and culture in Africa: anthropological applications in an emerging pandemic. Ethn Dis. 2003; 13(Suppl 2): S149–57.
21. Joshi R, Alim M, Kengne AP, Jan S, Maulik PK, Peiris D, etal. Task shifting for non-communicable disease management in low and middle income countries–A systematic review. PLoS One. 2014; 9: e103754.
22. Lewando Hundt G, Stuttaford M, Ngoma B. The social diagnostics of stroke-like symptoms: healers, doctors and prophets in Agincourt, Limpopo Province, South Africa. J Biosoc Sci. 2004; 36: 433–43.
23. Diouf A, Cournil A, Ba-Fall K, Ngom-Guèye NF, Eymard-Duvernay S, Ndiaye I, etal. Diabetes and hypertension among patients receiving antiretroviral treatment since in Senegal: prevalence and associated factors. ISRN AIDS. 2012; 2012: 621565.
24. Amuyunzu-Nyamongo M. Need for a multi-factorial, multi-sectorial and multi-disciplinary approach to NCD prevention and control in Africa. Glob Health Promot. 2010; 17(2 suppl): 31–2.
25. Giles WH, Pacque M, Greene BM, Taylor HR, Munoz B, Cutler M, etal. Prevalence of hypertension in rural west Africa. Am J Med Sci. 1994; 308: 271–5.
26. Scholten F, Mugisha J, Seeley J, Kinyanda E, Nakubukwa S, Kowal P, etal. Health and functional status among older people with HIV/AIDS in Uganda. BMC Public Health. 2011; 11: 886.
27. Wandera SO, Kwagala B, Ntozi J. Prevalence and risk factors for self-reported non-communicable diseases among older Ugandans: a cross-sectional study. Glob Health Action. 2015; 8: 27923,. doi: http://dx.doi.org/10.3402/gha.v8.27923.
28. Wandera SO, Ntozi J, Kwagala B. Prevalence and correlates of disability among older Ugandans: evidence from the Uganda National Household Survey. Glob Health Action. 2014; 7: 25686,. doi: http://dx.doi.org/10.3402/gha.v7.25686.
29. Wandera SO, Golaz V, Kwagala B, Ntozi J. Factors associated with self-reported ill health among older Ugandans: a cross sectional study. Arch Gerontol Geriatr. 2015; 61: 231–9.
30. Strong K, Mathers C, Leeder S, Beaglehole R. Preventing chronic diseases: how many lives can we save?. Lancet. 2005; 366: 1578–82.
31. Ezzati M, Lopez AD, Rodgers A, Vander Hoorn S, Murray CJ. Selected major risk factors and global and regional burden of disease. Lancet. 2002; 360: 1347–60.
32. Vita AJ, Terry RB, Hubert HB, Fries JF. Aging, health risks, and cumulative disability. New Engl J Med. 1998; 338: 1035–41.
33. LaCroix AZ, Guralnik JM, Berkman LF, Wallace RB, Satterfield S. Maintaining mobility in late life. II. Smoking, alcohol consumption, physical activity, and body mass index. Am J Epidemiol. 1993; 137: 858–69.
34. Magnusson R. Developing a global framework to address non-communicable diseases. Diabetes Voice. 2008; 53: 9–12.
35. Üstün TB, Chatterji S, Kostanjsek N, Rehm J, Kennedy C, Epping-Jordan J, etal. Developing the world health organization disability assessment schedule 2.0. Bull World Health Organ. 2010; 88: 815–23.
36. Mugisha J, Scholten F, Owilla S, Naidoo N, Seeley J, Chatterji S, etal. Caregiving responsibilities and burden among older people by HIV status and other determinants in Uganda. AIDS Care. 2013; 25: 1341–8.
37. Nakanjako D, Kamya M, Daniel K, Mayanja-Kizza H, Freers J, Whalen C, etal. Acceptance of routine testing for HIV among adult patients at the medical emergency unit at a national referral hospital in Kampala, Uganda. AIDS Behav. 2007; 11: 753–8.
38. Naidoo N, Abdullah S, Bawah A, Binka F, Chuc NT, Debpuur C, etal. Ageing and adult health status in eight lower-income countries: the INDEPTH WHO-SAGE collaboration. Glob Health Action. 2010; 115302, doi: http://dx.doi.org/10.3402/gha.v3i0.5302.
39. World Health Organization (International Society of Hypertension Writing Group). 2003 World Health Organization (WHO)/International Society of Hypertension (ISH) statement on management of hypertension. J Hypertens. 2003; 21: 1983–92.
40. Kowal P, Chatterji S, Naidoo N, Biritwum R, Fan W, Ridaura RL, etal. Data resource profile: the World Health Organization Study on global AGEing and adult health (SAGE). Int J Epidemiol. 2012; 41: 1639–49.
41. Moussavi S, Chatterji S, Verdes E, Tandon A, Patel V, Ustun B. Depression, chronic diseases, and decrements in health: results from the World Health Surveys. Lancet. 2007; 370: 851–8.
42. Folstein MF, Folstein SE, McHugh PR. “Mini-mental state”: a practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res. 1975; 12: 189–98.
43. Tombaugh TN, McIntyre NJ. The mini-mental state examination: a comprehensive review. J Am Geriatr Soc. 1992; 40: 922–35.
44. Crum RM, Anthony JC, Bassett SS, Folstein MF. Population-based norms for the Mini-Mental State Examination by age and educational level. JAMA. 1993; 269: 2386–91.
45. Nakimuli-Mpungu E, Mojtabai R, Alexandre PK, Katabira E, Musisi S, Nachega JB, etal. Cross-cultural adaptation and validation of the self-reporting questionnaire among HIV+ individuals in a rural ART program in southern Uganda. HIV AIDS (Auckl). 2012; 4: 51–60.
46. Petrushkin H, Boardman J, Ovuga E. Psychiatric disorders in HIV-positive individuals in urban Uganda. Psychiatrist. 2005; 29: 455–8.
47. Üstün TB. Measuring health and disability: manual for WHO Disability Assessment Schedule (WHODAS 2.0). 2010;, Geneva, Switzerland: World Health Organization.
48. Janca A, Kastrup M, Katschnig H, Lopez-Ibor J, Jr., Mezzich J, Sartorius N. The World Health Organization Short Disability Assessment Schedule (WHO DAS-S): a tool for the assessment of difficulties in selected areas of functioning of patients with mental disorders. Soc Psychiatry Psychiatr Epidemiol. 1996; 31: 349–54.
49. Rehm J, Üstün TB, Saxena S, Nelson CB, Chatterji S, Ivis F, etal. On the development and psychometric testing of the WHO screening instrument to assess disablement in the general population. Int J Meth Psychiatr Res. 1999; 8: 110–22.
50. Nyirenda M, Chatterji S, Falkingham J, Mutevedzi P, Hosegood V, Evandrou M, etal. An investigation of factors associated with the health and well-being of HIV-infected or HIV-affected older people in rural South Africa. BMC Public Health. 2012; 12: 259.
51. Gomez-Olive FX, Thorogood M, Clark BD, Kahn K, Tollman SM. Assessing health and well-being among older people in rural South Africa. Glob Health Action. 2010; 3(Suppl 2): 23–35.
52. Negin J, Nyirenda M, Seeley J, Mutevedzi P. Inequality in health status among older adults in Africa: the surprising impact of anti-retroviral treatment. J Cross Cult Gerontol. 2013; 28: 491–3.
53. Asiki G, Baisley K, Kamali A, Kaleebu P, Seeley J, Newton R. A prospective study of trends in consumption of cigarettes and alcohol among adults in a rural Ugandan population cohort, 1994–2011. Trop Med Int Health. 2015; 20: 527–36.
54. Anto J, Vermeire P, Vestbo J, Sunyer J. Epidemiology of chronic obstructive pulmonary disease. Eur Respir J. 2001; 17: 982–94.
55. Prescott E, Vestbo J. Socioeconomic status and chronic obstructive pulmonary disease. Thorax. 1999; 54: 737–41.
56. Mayosi BM, Flisher AJ, Lalloo UG, Sitas F, Tollman SM, Bradshaw D. The burden of non-communicable diseases in South Africa. Lancet. 2009; 374: 934–47.
57. Wright S, Zalwango F, Seeley J, Mugisha J, Scholten F. Despondency among HIV-positive older men and women in Uganda. J Cross Cult Gerontol. 2012; 27: 319–33.
58. Kuteesa MO, Seeley J, Cumming RG, Negin J. Older people living with HIV in Uganda: understanding their experience and needs. Afr J AIDS Res. 2012; 11: 295–305.
59. Courtenay WH. Constructions of masculinity and their influence on men's well-being: a theory of gender and health. Soc Sci Med. 2000; 50: 1385–401.
60. Shaikh BT, Hatcher J. Health seeking behaviour and health service utilization in Pakistan: challenging the policy makers. J Public Health. 2005; 27: 49–54.
61. Lawson D. Determinants of health seeking behaviour in Uganda: is it just income and user fees that are important?. 2004; Manchester: University of Manchester.
62. Schatz E, Gómez-Olivé X, Ralston M, Menken J, Tollman S. The impact of pensions on health and wellbeing in rural South Africa: does gender matter?. Soc Sci Med. 2012; 75: 1864–73.
63. Schatz E, Gilbert L. “My heart is very painful”: physical, mental and social wellbeing of older women at the times of HIV/AIDS in rural South Africa. J Aging Stud. 2012; 26: 16–25.
64. Schatz E, Gilbert L. My legs affect me a lot. … I can no longer walk to the forest to fetch firewood”: challenges related to health and the performance of daily tasks for older women in a high HIV context. Health Care Women Int. 2014; 35: 771–88.
65. Schatz E, Seeley J. Gender, ageing and carework in East and Southern Africa: a review. Glob Public Health. 2015; 10: 1185–200,. doi: http://dx.doi.org/10.1080/17441692.2015.1035664.
66. Abegunde DO, Mathers CD, Adam T, Ortegon M, Strong K. The burden and costs of chronic diseases in low-income and middle-income countries. Lancet. 2007; 370: 1929–38.
67. Ebrahim S, Smeeth L. Non-communicable diseases in low and middle-income countries: a priority or a distraction?. Int J Epidemiol. 2005; 34: 961–6.
68. Maher D, Waswa L, Baisley K, Karabarinde A, Unwin N, Grosskurth H. Distribution of hyperglycaemia and related cardiovascular disease risk factors in low-income countries: a cross-sectional population-based survey in rural Uganda. Int J Epidemiol. 2011; 40: 160–71.