-
2
-
-
84923917285
-
Prevalence of germline mutations in cancer predisposition genes in patients with pancreatic cancer
-
Grant RC, Selander I, Connor AA, et al. Prevalence of germline mutations in cancer predisposition genes in patients with pancreatic cancer. Gastroenterology. 2015; 148:556–564.
-
(2015)
Gastroenterology
, vol.148
, pp. 556-564
-
-
Grant, R.C.1
Selander, I.2
Connor, A.A.3
-
3
-
-
84949321701
-
Identification of germline genetic mutations in patients with pancreatic cancer
-
Salo-Mullen EE, O'reilly EM, Kelsen DP, et al. Identification of germline genetic mutations in patients with pancreatic cancer. Cancer. 2015; 121:4382–4388.
-
(2015)
Cancer
, vol.121
, pp. 4382-4388
-
-
Salo-Mullen, E.E.1
O'reilly, E.M.2
Kelsen, D.P.3
-
4
-
-
0023192463
-
Increased risk of cancer in the Peutz-Jeghers syndrome
-
Giardiello FM, Welsh SB, Hamilton SR, et al. Increased risk of cancer in the Peutz-Jeghers syndrome. N Engl J Med. 1987; 316:1511–1514.
-
(1987)
N Engl J Med
, vol.316
, pp. 1511-1514
-
-
Giardiello, F.M.1
Welsh, S.B.2
Hamilton, S.R.3
-
5
-
-
0033836334
-
Risk of developing pancreatic cancer in families with familial atypical multiple mole melanoma associated with a specific 19 deletion of p16 (p16-Leiden)
-
Vasen H, Gruis N, Frants R, van Der Velden P, Hille E, Bergman W. Risk of developing pancreatic cancer in families with familial atypical multiple mole melanoma associated with a specific 19 deletion of p16 (p16-Leiden). Int J Cancer. 2000; 87:809–811.
-
(2000)
Int J Cancer
, vol.87
, pp. 809-811
-
-
Vasen, H.1
Gruis, N.2
Frants, R.3
van Der Velden, P.4
Hille, E.5
Bergman, W.6
-
6
-
-
84863830403
-
ATM mutations in patients with hereditary pancreatic cancer
-
Roberts NJ, Jiao Y, Yu J, et al. ATM mutations in patients with hereditary pancreatic cancer. Cancer Discov. 2012; 2:41–46.
-
(2012)
Cancer Discov
, vol.2
, pp. 41-46
-
-
Roberts, N.J.1
Jiao, Y.2
Yu, J.3
-
7
-
-
28044467767
-
Management strategies for patients with hereditary pancreatic cancer
-
Brentnall TA. Management strategies for patients with hereditary pancreatic cancer. Curr Treat Options Oncol. 2005; 6:437–445.
-
(2005)
Curr Treat Options Oncol
, vol.6
, pp. 437-445
-
-
Brentnall, T.A.1
-
8
-
-
11144353646
-
Prospective risk of pancreatic cancer in familial pancreatic cancer kindreds
-
Klein AP, Brune KA, Petersen GM, et al. Prospective risk of pancreatic cancer in familial pancreatic cancer kindreds. Cancer Res. 2004; 64:2634–2638.
-
(2004)
Cancer Res
, vol.64
, pp. 2634-2638
-
-
Klein, A.P.1
Brune, K.A.2
Petersen, G.M.3
-
11
-
-
84864299220
-
Cigarette smoking and pancreatic cancer: an analysis from the International Pancreatic Cancer Case-Control Consortium (Panc4)
-
Bosetti C, Lucenteforte E, Silverman D, et al. Cigarette smoking and pancreatic cancer: an analysis from the International Pancreatic Cancer Case-Control Consortium (Panc4). Ann Oncol. 2012; 23:1880–1888.
-
(2012)
Ann Oncol
, vol.23
, pp. 1880-1888
-
-
Bosetti, C.1
Lucenteforte, E.2
Silverman, D.3
-
13
-
-
84902144290
-
Association of diabetes mellitus and pancreatic adenocarcinoma: a meta-analysis of 88 studies
-
Batabyal P, Vander Hoorn S, Christophi C, Nikfarjam M. Association of diabetes mellitus and pancreatic adenocarcinoma: a meta-analysis of 88 studies. Ann Surg Oncol. 2014; 21:2453–2462.
-
(2014)
Ann Surg Oncol
, vol.21
, pp. 2453-2462
-
-
Batabyal, P.1
Vander Hoorn, S.2
Christophi, C.3
Nikfarjam, M.4
-
14
-
-
0035934044
-
Physical activity, obesity, height, and the risk of pancreatic cancer
-
Michaud DS, Giovannucci E, Willett WC, Colditz GA, Stampfer MJ, Fuchs CS. Physical activity, obesity, height, and the risk of pancreatic cancer. JAMA. 2001; 286:921–929.
-
(2001)
JAMA
, vol.286
, pp. 921-929
-
-
Michaud, D.S.1
Giovannucci, E.2
Willett, W.C.3
Colditz, G.A.4
Stampfer, M.J.5
Fuchs, C.S.6
-
15
-
-
84884611811
-
Association between Helicobacter pylori infection and pancreatic cancer development: a meta-analysis
-
Xiao M, Wang Y, Gao Y. Association between Helicobacter pylori infection and pancreatic cancer development: a meta-analysis. PLoS ONE. 2013; 8:e75559.
-
(2013)
PLoS ONE
, vol.8
-
-
Xiao, M.1
Wang, Y.2
Gao, Y.3
-
16
-
-
53749101443
-
Association between hepatitis B virus and pancreatic cancer
-
Hassan MM, Li D, El-Deeb AS, et al. Association between hepatitis B virus and pancreatic cancer. J Clin Oncol. 2008; 26:4557–4562.
-
(2008)
J Clin Oncol
, vol.26
, pp. 4557-4562
-
-
Hassan, M.M.1
Li, D.2
El-Deeb, A.S.3
-
17
-
-
78651090526
-
Controversies in the management of pancreatic IPMN
-
Tanaka M. Controversies in the management of pancreatic IPMN. Nat Rev Gastroenterol Hepatol. 2011; 8:56–60.
-
(2011)
Nat Rev Gastroenterol Hepatol
, vol.8
, pp. 56-60
-
-
Tanaka, M.1
-
18
-
-
62249206562
-
An algorithmic approach to the diagnosis of pancreatic neoplasms
-
Klimstra DS, Pitman MB, Hruban RH. An algorithmic approach to the diagnosis of pancreatic neoplasms. Arch Pathol Lab Med. 2009; 133:454–464.
-
(2009)
Arch Pathol Lab Med
, vol.133
, pp. 454-464
-
-
Klimstra, D.S.1
Pitman, M.B.2
Hruban, R.H.3
-
19
-
-
0018742498
-
Relation of pancreatic duct hyperplasia to carcinoma
-
Kozuka S, Sassa R, Taki T, et al. Relation of pancreatic duct hyperplasia to carcinoma. Cancer. 1979; 43:1418–1428.
-
(1979)
Cancer
, vol.43
, pp. 1418-1428
-
-
Kozuka, S.1
Sassa, R.2
Taki, T.3
-
20
-
-
24044500647
-
Exocrine pancreatic cancer: symptoms at presentation and their relation to tumor site and stage
-
Porta M, Fabregat X, Malats N, et al. Exocrine pancreatic cancer: symptoms at presentation and their relation to tumor site and stage. Clin Transl Oncol 2005; 7:189–197.
-
(2005)
Clin Transl Oncol
, vol.7
, pp. 189-197
-
-
Porta, M.1
Fabregat, X.2
Malats, N.3
-
21
-
-
13944260238
-
Pancreatic cancer and thromboembolic disease
-
Khorana AA, Fine RL. Pancreatic cancer and thromboembolic disease. Lancet Oncol. 2004; 5:655–663.
-
(2004)
Lancet Oncol
, vol.5
, pp. 655-663
-
-
Khorana, A.A.1
Fine, R.L.2
-
26
-
-
28644437297
-
CA 19-9 levels predict results of staging laparoscopy in pancreatic cancer
-
Karachristos A, Scarmeas N, Hoffman JP. CA 19-9 levels predict results of staging laparoscopy in pancreatic cancer. J Gastrointest Surg. 2005; 9:1286–1292.
-
(2005)
J Gastrointest Surg
, vol.9
, pp. 1286-1292
-
-
Karachristos, A.1
Scarmeas, N.2
Hoffman, J.P.3
-
27
-
-
85021360559
-
PET-PANC: multi-centre prospective diagnostic accuracy and clinical value study of PET/CT in the diagnosis and management of pancreatic cancer
-
Ghaneh P, Wong WL, Titman A, et al. PET-PANC: multi-centre prospective diagnostic accuracy and clinical value study of PET/CT in the diagnosis and management of pancreatic cancer. Pancreatology. 2016; 16:S91.
-
(2016)
Pancreatology
, vol.16
, pp. S91
-
-
Ghaneh, P.1
Wong, W.L.2
Titman, A.3
-
28
-
-
0024577341
-
Evaluation of a serologic marker, CA19-9, in the diagnosis of pancreatic cancer
-
Pleskow DK, Berger HJ, Gyves J, Allen E, McLean A, Podolsky DK. Evaluation of a serologic marker, CA19-9, in the diagnosis of pancreatic cancer. Ann Intern Med. 1989; 110:704–709.
-
(1989)
Ann Intern Med
, vol.110
, pp. 704-709
-
-
Pleskow, D.K.1
Berger, H.J.2
Gyves, J.3
Allen, E.4
McLean, A.5
Podolsky, D.K.6
-
29
-
-
33750075730
-
Cancer antigens 19-9 and 125 in the differential diagnosis of pancreatic mass lesions
-
Ćwik G, Wallner G, Skoczylas T, Ciechański A, Zinkiewicz K. Cancer antigens 19-9 and 125 in the differential diagnosis of pancreatic mass lesions. Arch Surg. 2006; 141:968–973.
-
(2006)
Arch Surg
, vol.141
, pp. 968-973
-
-
Ćwik, G.1
Wallner, G.2
Skoczylas, T.3
Ciechański, A.4
Zinkiewicz, K.5
-
31
-
-
0023903792
-
CA 19-9 and CA 50 in benign and malignant pancreatic and biliary diseases
-
CONIO M. CA 19-9 and CA 50 in benign and malignant pancreatic and biliary diseases. Cancer. 1988; 61:2100–2108.
-
(1988)
Cancer
, vol.61
, pp. 2100-2108
-
-
Conio, M.1
-
32
-
-
0023242603
-
Determination of CA 19-9 antigen in serum and pancreatic juice for differential diagnosis of pancreatic adenocarcinoma from chronic pancreatitis
-
Malesci A, Tommasini MA, Bonato C, et al. Determination of CA 19-9 antigen in serum and pancreatic juice for differential diagnosis of pancreatic adenocarcinoma from chronic pancreatitis. Gastroenterology. 1987; 92:60–67.
-
(1987)
Gastroenterology
, vol.92
, pp. 60-67
-
-
Malesci, A.1
Tommasini, M.A.2
Bonato, C.3
-
33
-
-
0032783998
-
Role of tumor markers, cytogenetics
-
Lamerz R. Role of tumor markers, cytogenetics. Ann Oncol. 1999; 10:S145–S149.
-
(1999)
Ann Oncol
, vol.10
, pp. S145-S149
-
-
Lamerz, R.1
-
34
-
-
31544450588
-
Serum markers in patients with resectable pancreatic adenocarcinoma: macrophage inhibitory cytokine 1 versus CA 19-9
-
Koopmann J, Rosenzweig CNW, Zhang Z, et al. Serum markers in patients with resectable pancreatic adenocarcinoma: macrophage inhibitory cytokine 1 versus CA 19-9. Clin Cancer Res. 2006; 12:442–446.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 442-446
-
-
Koopmann, J.1
Rosenzweig, C.N.W.2
Zhang, Z.3
-
35
-
-
78751681675
-
-
eds. Pancreas cancer staging. AJCC (American Joint Committee on Cancer) Cancer Staging Manual., NY, USA, Springer
-
Edge SB, Compton CC, Byrd DR, et al. eds. Pancreas cancer staging. AJCC (American Joint Committee on Cancer) Cancer Staging Manual. NY, USA: Springer; 2010; 7:241–249.
-
(2010)
, vol.7
, pp. 241-249
-
-
Edge, S.B.1
Compton, C.C.2
Byrd, D.R.3
-
36
-
-
85021321345
-
-
NY, USA, Springer
-
Manual AS, Edge SB, Byrd DR, et al. NY, USA: Springer; 2010; 7:241–249.
-
(2010)
, vol.7
, pp. 241-249
-
-
Manual, A.S.1
Edge, S.B.2
Byrd, D.R.3
-
37
-
-
26444467172
-
Long-term survival is superior after resection for cancer in high-volume centers
-
Fong Y, Gonen M, Rubin D, Radzyner M, Brennan MF. Long-term survival is superior after resection for cancer in high-volume centers. Ann Surg. 2005; 242:540–547.
-
(2005)
Ann Surg
, vol.242
, pp. 540-547
-
-
Fong, Y.1
Gonen, M.2
Rubin, D.3
Radzyner, M.4
Brennan, M.F.5
-
38
-
-
77951755278
-
Pancreatic cancer
-
Hidalgo M. Pancreatic cancer. N Engl J Med. 2010; 362:1605–1617.
-
(2010)
N Engl J Med
, vol.362
, pp. 1605-1617
-
-
Hidalgo, M.1
-
40
-
-
67649227286
-
Surgical treatment of resectable and borderline resectable pancreas cancer: expert consensus statement
-
Evans DB, Farnell MB, Lillemoe KD, Vollmer C Jr, Strasberg SM, Schulick RD. Surgical treatment of resectable and borderline resectable pancreas cancer: expert consensus statement. Ann Surg Oncol. 2009; 16:1736–1744.
-
(2009)
Ann Surg Oncol
, vol.16
, pp. 1736-1744
-
-
Evans, D.B.1
Farnell, M.B.2
Lillemoe, K.D.3
Vollmer, C.4
Strasberg, S.M.5
Schulick, R.D.6
-
43
-
-
67649213568
-
Combined modality treatment of resectable and borderline resectable pancreas cancer: expert consensus statement
-
Abrams RA, Lowy AM, O'Reilly EM, Wolff RA, Picozzi VJ, Pisters PW. Combined modality treatment of resectable and borderline resectable pancreas cancer: expert consensus statement. Ann Surg Oncol. 2009; 16:1751–1756.
-
(2009)
Ann Surg Oncol
, vol.16
, pp. 1751-1756
-
-
Abrams, R.A.1
Lowy, A.M.2
O'Reilly, E.M.3
Wolff, R.A.4
Picozzi, V.J.5
Pisters, P.W.6
-
44
-
-
84896872886
-
Intensity of follow-up after pancreatic cancer resection
-
Castellanos JA, Merchant NB. Intensity of follow-up after pancreatic cancer resection. Ann Surg Oncol. 2014; 21:747–751.
-
(2014)
Ann Surg Oncol
, vol.21
, pp. 747-751
-
-
Castellanos, J.A.1
Merchant, N.B.2
-
46
-
-
85016281515
-
A myriad of symptoms: new approaches to optimizing palliative care of patients with advanced pancreatic cancer
-
Wiebe LA. A myriad of symptoms: new approaches to optimizing palliative care of patients with advanced pancreatic cancer. Am Soc Clin Oncol Educ Book. 2012; 32:243–248.
-
(2012)
Am Soc Clin Oncol Educ Book
, vol.32
, pp. 243-248
-
-
Wiebe, L.A.1
-
47
-
-
80052997944
-
Randomized, double-blind, controlled trial of early endoscopic ultrasound—guided celiac plexus neurolysis to prevent pain progression in patients with newly diagnosed, painful, inoperable pancreatic cancer
-
Wyse JM, Carone M, Paquin SC, Usatii M, Sahai AV. Randomized, double-blind, controlled trial of early endoscopic ultrasound—guided celiac plexus neurolysis to prevent pain progression in patients with newly diagnosed, painful, inoperable pancreatic cancer. J Clin Oncol. 2011; 29:3541–3546.
-
(2011)
J Clin Oncol
, vol.29
, pp. 3541-3546
-
-
Wyse, J.M.1
Carone, M.2
Paquin, S.C.3
Usatii, M.4
Sahai, A.V.5
-
48
-
-
79951587169
-
Pancreatic exocrine insufficiency: diagnosis and treatment
-
Domínguez-Muñoz JE. Pancreatic exocrine insufficiency: diagnosis and treatment. J Gastroenterol Hepatol. 2011; 26:12–16.
-
(2011)
J Gastroenterol Hepatol
, vol.26
, pp. 12-16
-
-
Domínguez-Muñoz, J.E.1
-
49
-
-
81155144602
-
Partial pancreatic resection for pancreatic malignancy is associated with sustained pancreatic exocrine failure and reduced quality of life: a prospective study
-
Halloran CM, Cox TF, Chauhan S, et al. Partial pancreatic resection for pancreatic malignancy is associated with sustained pancreatic exocrine failure and reduced quality of life: a prospective study. Pancreatology. 2011; 11:535–545.
-
(2011)
Pancreatology
, vol.11
, pp. 535-545
-
-
Halloran, C.M.1
Cox, T.F.2
Chauhan, S.3
-
51
-
-
33748365398
-
Borderline resectable pancreatic cancer: definitions, management, and role of preoperative therapy
-
Varadhachary GR, Tamm EP, Abbruzzese JL, et al. Borderline resectable pancreatic cancer: definitions, management, and role of preoperative therapy. Ann Surg Oncol. 2006; 13:1035–1046.
-
(2006)
Ann Surg Oncol
, vol.13
, pp. 1035-1046
-
-
Varadhachary, G.R.1
Tamm, E.P.2
Abbruzzese, J.L.3
-
52
-
-
80052293264
-
Neoadjuvant therapy in pancreatic adenocarcinoma: a meta-analysis of phase II trials
-
Assifi MM, Lu X, Eibl G, Reber HA, Li G, Hines OJ. Neoadjuvant therapy in pancreatic adenocarcinoma: a meta-analysis of phase II trials. Surgery. 2011; 150:466–473.
-
(2011)
Surgery
, vol.150
, pp. 466-473
-
-
Assifi, M.M.1
Lu, X.2
Eibl, G.3
Reber, H.A.4
Li, G.5
Hines, O.J.6
-
53
-
-
84928489481
-
FOLFIRINOX-based neoadjuvant therapy in borderline resectable or unresectable pancreatic cancer: a meta-analytical review of published studies
-
Petrelli F, Coinu A, Borgonovo K, et al. FOLFIRINOX-based neoadjuvant therapy in borderline resectable or unresectable pancreatic cancer: a meta-analytical review of published studies. Pancreas. 2015; 44:515–521.
-
(2015)
Pancreas
, vol.44
, pp. 515-521
-
-
Petrelli, F.1
Coinu, A.2
Borgonovo, K.3
-
54
-
-
84971631189
-
Effect of chemoradiotherapy vs chemotherapy on survival in patients with locally advanced pancreatic cancer controlled after 4 months of gemcitabine with or without erlotinib: the LAP07 randomized clinical trial
-
Hammel P, Huguet F, van Laethem J-L, et al. Effect of chemoradiotherapy vs chemotherapy on survival in patients with locally advanced pancreatic cancer controlled after 4 months of gemcitabine with or without erlotinib: the LAP07 randomized clinical trial. JAMA. 2016; 315:1844–1853.
-
(2016)
JAMA
, vol.315
, pp. 1844-1853
-
-
Hammel, P.1
Huguet, F.2
van Laethem, J.-L.3
-
55
-
-
62149143713
-
Long-term survival after multidisciplinary management of resected pancreatic adenocarcinoma
-
Katz MH, Wang H, Fleming JB, et al. Long-term survival after multidisciplinary management of resected pancreatic adenocarcinoma. Ann Surg Oncol. 2009; 16:836–847.
-
(2009)
Ann Surg Oncol
, vol.16
, pp. 836-847
-
-
Katz, M.H.1
Wang, H.2
Fleming, J.B.3
-
56
-
-
0035841631
-
Adjuvant chemoradiotherapy and chemotherapy in resectable pancreatic cancer: a randomised controlled trial
-
Neoptolemos J, Dunn J, Stocken D, et al. Adjuvant chemoradiotherapy and chemotherapy in resectable pancreatic cancer: a randomised controlled trial. Lancet. 2001; 358:1576–1585.
-
(2001)
Lancet
, vol.358
, pp. 1576-1585
-
-
Neoptolemos, J.1
Dunn, J.2
Stocken, D.3
-
57
-
-
12144287320
-
A randomized trial of chemoradiotherapy and chemotherapy after resection of pancreatic cancer
-
Neoptolemos JP, Stocken DD, Friess H, et al. A randomized trial of chemoradiotherapy and chemotherapy after resection of pancreatic cancer. N Engl J Med. 2004; 350:1200–1210.
-
(2004)
N Engl J Med
, vol.350
, pp. 1200-1210
-
-
Neoptolemos, J.P.1
Stocken, D.D.2
Friess, H.3
-
58
-
-
33846405332
-
Adjuvant chemotherapy with gemcitabine vs observation in patients undergoing curative-intent resection of pancreatic cancer: a randomized controlled trial
-
Oettle H, Post S, Neuhaus P, et al. Adjuvant chemotherapy with gemcitabine vs observation in patients undergoing curative-intent resection of pancreatic cancer: a randomized controlled trial. JAMA. 2007; 297:267–277.
-
(2007)
JAMA
, vol.297
, pp. 267-277
-
-
Oettle, H.1
Post, S.2
Neuhaus, P.3
-
59
-
-
84885462618
-
Adjuvant chemotherapy with gemcitabine and long-term outcomes among patients with resected pancreatic cancer: the CONKO-001 randomized trial
-
Oettle H, Neuhaus P, Hochhaus A, et al. Adjuvant chemotherapy with gemcitabine and long-term outcomes among patients with resected pancreatic cancer: the CONKO-001 randomized trial. JAMA. 2013; 310:1473–1481.
-
(2013)
JAMA
, vol.310
, pp. 1473-1481
-
-
Oettle, H.1
Neuhaus, P.2
Hochhaus, A.3
-
60
-
-
85011349966
-
Comparison of adjuvant gemcitabine and capecitabine with gemcitabine monotherapy in patients with resected pancreatic cancer (ESPAC-4): a multicentre, open-label, randomised, phase 3 trial
-
Neoptolemos JP, Palmer DH, Ghaneh P, et al. Comparison of adjuvant gemcitabine and capecitabine with gemcitabine monotherapy in patients with resected pancreatic cancer (ESPAC-4): a multicentre, open-label, randomised, phase 3 trial. Lancet. 2017; 389:1011–1024.
-
(2017)
Lancet
, vol.389
, pp. 1011-1024
-
-
Neoptolemos, J.P.1
Palmer, D.H.2
Ghaneh, P.3
-
61
-
-
40449113435
-
Fluorouracil vs gemcitabine chemotherapy before and after fluorouracil-based chemoradiation following resection of pancreatic adenocarcinoma: a randomized controlled trial
-
Regine WF, Winter KA, Abrams RA, et al. Fluorouracil vs gemcitabine chemotherapy before and after fluorouracil-based chemoradiation following resection of pancreatic adenocarcinoma: a randomized controlled trial. JAMA. 2008; 299:1019–1026.
-
(2008)
JAMA
, vol.299
, pp. 1019-1026
-
-
Regine, W.F.1
Winter, K.A.2
Abrams, R.A.3
-
62
-
-
85021384745
-
ESPAC-4: a multicenter, international, open label randomized controlled phase III trial of adjuvant combination chemotherapy of gemcitabine (GEM) and capecitabine (CAP), versus monotherapy gemcitabine in patients with resected pancreatic ductal adenocarcinoma
-
Neoptolemos J, Palmer D, Ghaneh P, et al. ESPAC-4: a multicenter, international, open label randomized controlled phase III trial of adjuvant combination chemotherapy of gemcitabine (GEM) and capecitabine (CAP), versus monotherapy gemcitabine in patients with resected pancreatic ductal adenocarcinoma. Pancreatology. 2016; 16:S63.
-
(2016)
Pancreatology
, vol.16
, pp. S63
-
-
Neoptolemos, J.1
Palmer, D.2
Ghaneh, P.3
-
63
-
-
8244254377
-
Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: a randomized trial
-
Burris HR, Moore MJ, Andersen J, et al. Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: a randomized trial. J Clin Oncol. 1997; 15:2403–2413.
-
(1997)
J Clin Oncol
, vol.15
, pp. 2403-2413
-
-
Burris, H.R.1
Moore, M.J.2
Andersen, J.3
-
64
-
-
34249933404
-
Erlotinib plus gemcitabine compared with gemcitabine alone in patients with advanced pancreatic cancer: a phase III trial of the National Cancer Institute of Canada Clinical Trials Group
-
Moore MJ, Goldstein D, Hamm J, et al. Erlotinib plus gemcitabine compared with gemcitabine alone in patients with advanced pancreatic cancer: a phase III trial of the National Cancer Institute of Canada Clinical Trials Group. J Clin Oncol. 2007; 25:1960–1966.
-
(2007)
J Clin Oncol
, vol.25
, pp. 1960-1966
-
-
Moore, M.J.1
Goldstein, D.2
Hamm, J.3
-
65
-
-
78650095716
-
Molecular predictors of outcome in a phase 3 study of gemcitabine and erlotinib therapy in patients with advanced pancreatic cancer
-
da Cunha Santos G, Dhani N, Tu D, et al. Molecular predictors of outcome in a phase 3 study of gemcitabine and erlotinib therapy in patients with advanced pancreatic cancer. Cancer. 2010; 116:5599–5607.
-
(2010)
Cancer
, vol.116
, pp. 5599-5607
-
-
da Cunha Santos, G.1
Dhani, N.2
Tu, D.3
-
66
-
-
84927176540
-
Dose escalation to rash for erlotinib plus gemcitabine in patients with metastatic pancreatic cancer: the phase II Rachel (BO21128) study
-
Van Cutsem E, Nowara E, Ciuleanu T, et al. Dose escalation to rash for erlotinib plus gemcitabine in patients with metastatic pancreatic cancer: the phase II Rachel (BO21128) study. Br J Cancer. 2014; 111:2067–2075.
-
(2014)
Br J Cancer
, vol.111
, pp. 2067-2075
-
-
Van Cutsem, E.1
Nowara, E.2
Ciuleanu, T.3
-
67
-
-
79955921754
-
FOLFIRINOX versus gemcitabine for metastatic pancreatic cancer
-
Conroy T, Desseigne F, Ychou M, et al. FOLFIRINOX versus gemcitabine for metastatic pancreatic cancer. N Engl J Med. 2011; 364:1817–1825.
-
(2011)
N Engl J Med
, vol.364
, pp. 1817-1825
-
-
Conroy, T.1
Desseigne, F.2
Ychou, M.3
-
68
-
-
84886741654
-
Results of a randomized phase III trial (MPACT) of weekly nab-paclitaxel plus gemcitabine versus gemcitabine alone for patients with metastatic adenocarcinoma of the pancreas with PET and CA19-9 correlates
-
Von Hoff DD, Ervin TJ, Arena FP, et al. Results of a randomized phase III trial (MPACT) of weekly nab-paclitaxel plus gemcitabine versus gemcitabine alone for patients with metastatic adenocarcinoma of the pancreas with PET and CA19-9 correlates. Am Soc Clin Oncol. 2013; 369:1691–1703.
-
(2013)
Am Soc Clin Oncol
, vol.369
, pp. 1691-1703
-
-
Von Hoff, D.D.1
Ervin, T.J.2
Arena, F.P.3
-
69
-
-
84905817411
-
Second-line oxaliplatin, folinic acid, and fluorouracil versus folinic acid and fluorouracil alone for gemcitabine-refractory pancreatic cancer: outcomes from the CONKO-003 trial
-
Oettle H, Riess H, Stieler JM, et al. Second-line oxaliplatin, folinic acid, and fluorouracil versus folinic acid and fluorouracil alone for gemcitabine-refractory pancreatic cancer: outcomes from the CONKO-003 trial. J Clin Oncol. 2014; 32:2423–2429.
-
(2014)
J Clin Oncol
, vol.32
, pp. 2423-2429
-
-
Oettle, H.1
Riess, H.2
Stieler, J.M.3
-
70
-
-
84959459386
-
Nanoliposomal irinotecan with fluorouracil and folinic acid in metastatic pancreatic cancer after previous gemcitabine-based therapy (NAPOLI-1): a global, randomised, open-label, phase 3 trial
-
Wang-Gillam A, Li C-P, Bodoky G, et al. Nanoliposomal irinotecan with fluorouracil and folinic acid in metastatic pancreatic cancer after previous gemcitabine-based therapy (NAPOLI-1): a global, randomised, open-label, phase 3 trial. Lancet. 2016; 387:545–557.
-
(2016)
Lancet
, vol.387
, pp. 545-557
-
-
Wang-Gillam, A.1
Li, C.-P.2
Bodoky, G.3
-
71
-
-
84995527140
-
PANCREOX: a randomized phase III study of Fluorouracil/Leucovorin with or without oxaliplatin for second-line advanced pancreatic cancer in patients who have received gemcitabine-based chemotherapy
-
Gill S, Ko Y-J, Cripps C, et al. PANCREOX: a randomized phase III study of Fluorouracil/Leucovorin with or without oxaliplatin for second-line advanced pancreatic cancer in patients who have received gemcitabine-based chemotherapy. J Clin Oncol. 2016; 34:3914–3920.
-
(2016)
J Clin Oncol
, vol.34
, pp. 3914-3920
-
-
Gill, S.1
Ko, Y.-J.2
Cripps, C.3
-
72
-
-
85018599183
-
Effect of selumetinib and MK-2206 vs oxaliplatin and fluorouracil in patients with metastatic pancreatic cancer after prior therapy: sWOG S1115 study randomized clinical trial
-
Chung V, McDonough S, Philip PA, et al. Effect of selumetinib and MK-2206 vs oxaliplatin and fluorouracil in patients with metastatic pancreatic cancer after prior therapy: sWOG S1115 study randomized clinical trial. JAMA Oncol. 2016.
-
(2016)
JAMA Oncol
-
-
Chung, V.1
McDonough, S.2
Philip, P.A.3
-
73
-
-
85006268239
-
Programmed death-1 blockade in mismatch repair deficient cancer independent of tumor histology
-
Diaz L, Uram J, Wang H, et al. Programmed death-1 blockade in mismatch repair deficient cancer independent of tumor histology. J Clin Oncol. 2016; 34:3003.
-
(2016)
J Clin Oncol
, vol.34
, pp. 3003
-
-
Diaz, L.1
Uram, J.2
Wang, H.3
-
74
-
-
85021361704
-
A randomized phase 2 study of the Bruton tyrosine kinase (Btk) inhibitor acalabrutinib alone or with pembrolizumab for metastatic pancreatic cancer (mPC)
-
Overman MJ, Lopez CD, Benson AB, et al. A randomized phase 2 study of the Bruton tyrosine kinase (Btk) inhibitor acalabrutinib alone or with pembrolizumab for metastatic pancreatic cancer (mPC). In ASCO Annual Meeting Proceedings. 2016.
-
(2016)
In, ASCO Annual Meeting Proceedings
-
-
Overman, M.J.1
Lopez, C.D.2
Benson, A.B.3
-
75
-
-
84903187931
-
A phase 2, randomized trial of GVAX pancreas and CRS-207 immunotherapy versus GVAX alone in patients with metastatic pancreatic adenocarcinoma: updated results
-
Le DT, Wang-Gillam A, Picozzi V, et al. A phase 2, randomized trial of GVAX pancreas and CRS-207 immunotherapy versus GVAX alone in patients with metastatic pancreatic adenocarcinoma: updated results. J Clin Oncol. 2014; 32:177.
-
(2014)
J Clin Oncol
, vol.32
, pp. 177
-
-
Le, D.T.1
Wang-Gillam, A.2
Picozzi, V.3
-
76
-
-
85021384504
-
A phase IIb, randomized, controlled, multicenter, open-label study of the efficacy and immune response of GVAX pancreas vaccine and CRS-207 compared to chemotherapy or to CRS-207 alone in adults with previously treated metastatic pancreatic adenocarcinoma (ECLIPSE Study)
-
Le DT, Wang-Gillam A, Picozzi VJ, et al. A phase IIb, randomized, controlled, multicenter, open-label study of the efficacy and immune response of GVAX pancreas vaccine and CRS-207 compared to chemotherapy or to CRS-207 alone in adults with previously treated metastatic pancreatic adenocarcinoma (ECLIPSE Study). J Clin Oncol. 2015; 33:TPS489–TPS489.
-
(2015)
J Clin Oncol
, vol.33
, pp. TPS489
-
-
Le, D.T.1
Wang-Gillam, A.2
Picozzi, V.J.3
-
77
-
-
85021321410
-
Systemic treatment with anti-PD-1 antibody nivolumab in combination with vaccine therapy in advanced pancreatic cancer
-
Nesselhut J, Marx D, Lange H, et al. Systemic treatment with anti-PD-1 antibody nivolumab in combination with vaccine therapy in advanced pancreatic cancer. in ASCO Annual Meeting Proceedings. 2016.
-
(2016)
ASCO Annual Meeting Proceedings
-
-
Nesselhut, J.1
Marx, D.2
Lange, H.3
-
78
-
-
84928965963
-
P53MVA therapy in patients with refractory gastrointestinal malignancies elevates p53-specific CD8+ T-cell responses
-
Hardwick NR, Carroll M, Kaltcheva T, et al. P53MVA therapy in patients with refractory gastrointestinal malignancies elevates p53-specific CD8+ T-cell responses. Clin Cancer Res. 2014; 20:4459–4470.
-
(2014)
Clin Cancer Res
, vol.20
, pp. 4459-4470
-
-
Hardwick, N.R.1
Carroll, M.2
Kaltcheva, T.3
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