Antithrombotic Therapy for Prevention of Cerebral Thromboembolic Events After Transcatheter Aortic Valve Replacement: Evolving Paradigms and Ongoing Directions

JACC: Cardiovascular Interventions

Volumn 10, Issue 13, 2017, Pages 1366-1369

  Capodanno, Davide ^a   Angiolillo, Dominick J ^b  

^a UNIVERSITY OF CATANIA   (Italy)

^b UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

Author keywords

anticoagulant therapy; antiplatelet therapy; antithrombotic therapy; TAVR

Indexed keywords

ACETYLSALICYLIC ACID; ACETYLSALICYLIC ACID PLUS CLOPIDOGREL; ANTICOAGULANT AGENT; CLOPIDOGREL; FIBRINOLYTIC AGENT;

ANTICOAGULANT THERAPY; BLEEDING; BRAIN EMBOLISM; BRAIN ISCHEMIA; DUAL ANTIPLATELET THERAPY; EDITORIAL; HEART INFARCTION; HUMAN; MULTICENTER STUDY (TOPIC); PERCUTANEOUS AORTIC VALVE; POSTOPERATIVE COMPLICATION; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); THROMBOEMBOLISM; THROMBOSIS PREVENTION; TRANSCATHETER AORTIC VALVE IMPLANTATION; TRANSIENT ISCHEMIC ATTACK; AORTIC VALVE; SURGERY;

AORTIC VALVE; ASPIRIN; CLOPIDOGREL; FIBRINOLYTIC AGENTS; TRANSCATHETER AORTIC VALVE REPLACEMENT;

EID: 85020013265     PISSN: 19368798     EISSN: 18767605     Source Type: Journal    
DOI: 10.1016/j.jcin.2017.05.005     Document Type: Editorial

References (12)

1. Leon, M.B., Smith, C.R., Mack, M.J., et al., for the PARTNER 2 Investigators. Transcatheter or surgical aortic-valve replacement in intermediate-risk patients. N Engl J Med 374 (2016), 1609–1620.
2. Reardon, M.J., Van Mieghem, N.M., Popma, J.J., et al., for the SURTAVI Investigators. Surgical or transcatheter aortic-valve replacement in intermediate-risk patients. N Engl J Med 376 (2017), 1321–1331.
3. Capodanno, D., Angiolillo, D.J., Antithrombotic therapy in the elderly. J Am Coll Cardiol 56 (2010), 1683–1692.
4. Capodanno, D., Leon, M.B., Upcoming TAVI trials: rationale, design and impact on clinical practice. EuroIntervention 12 (2016), Y51–Y55.
5. Rodés-Cabau, J., Masson, J.-B., Welsh, R.C., et al. Aspirin versus aspirin plus clopidogrel as antithrombotic treatment following transcatheter aortic valve replacement with a balloon-expandable valve: the ARTE (aspirin versus aspirin + clopidogrel following transcatheter aortic valve implantation) randomized clinical trial. J Am Coll Cardiol Intv 10 (2017), 1357–1365.
6. Ussia, G.P., Scarabelli, M., Mule, M., et al. Dual antiplatelet therapy versus aspirin alone in patients undergoing transcatheter aortic valve implantation. Am J Cardiol 108 (2011), 1772–1776.
7. Stabile, E., Pucciarelli, A., Cota, L., et al. SAT-TAVI (Single Antiplatelet Therapy for TAVI) study: a pilot randomized study comparing double to single antiplatelet therapy for transcatheter aortic valve implantation. Int J Cardiol 174 (2014), 624–627.
8. Nishimura, R.A., Otto, C.M., Bonow, R.O., et al. 2017 AHA/ACC focused update of the 2014 AHA/ACC guideline for the management of patients with valvular heart disease: a report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. J Am Coll Cardiol, 2017 Mar 10 [E-pub ahead of print].
9. Nijenhuis, V.J., Bennaghmouch, N., van Kuijk, J.P., Capodanno, D., ten Berg, J.M., Antithrombotic treatment in patients undergoing transcatheter aortic valve implantation (TAVI). Thromb Haemost 113 (2015), 674–685.
10. Kapadia, S.R., Kodali, S., Makkar, R., et al., for the SENTINEL Trial Investigators. Protection against cerebral embolism during transcatheter aortic valve replacement. J Am Coll Cardiol 69 (2017), 367–377.
11. Chakravarty, T., Sondergaard, L., Friedman, J., et al., for the RESOLVE and SAVORY Investigators. Subclinical leaflet thrombosis in surgical and transcatheter bioprosthetic aortic valves: an observational study. Lancet, 2017 Mar 19 [E-pub ahead of print].
12. Barbanti, M., Gulino, S., Tamburino, C., Capodanno, D., Antithrombotic therapy following transcatheter aortic valve implantation: what challenge do we face?. Expert Rev Cardiovasc Ther 14 (2016), 381–389.