Multimodality imaging approach in the diagnosis of chronic myocarditis with preserved left ventricular ejection fraction (MCpEF): The role of 2D speckle-tracking echocardiography

International Journal of Cardiology

Volumn 243, Issue , 2017, Pages 374-378

  Kasner, Mario ^a   Aleksandrov, Aleksandar ^a   Escher, Felicitas ^a   Al Saadi, Nidal ^b   Makowski, Markus ^a   Spillmann, Frank ^a   Genger, Martin ^a   Schultheiss, Heinz Peter ^c   Kühl, Uwe ^a   Pieske, Burkert ^a,e   Morris, Daniel A ^a   Noutsias, Michel ^d   Tschöpe, Carsten ^a,e,f  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b Private Institute for Cardiovascular Medicine   (Germany)

^c Institute of Cardiac Diagnostics and Therapy (IKDT)   (Germany)

^d JENA UNIVERSITY HOSPITAL   (Germany)

^e DZHK GERMAN CENTRE FOR CARDIOVASCULAR RESEARCH   (Germany)

^f Berlin Brandenburg Center for Regenerative Therapies   (Germany)

Author keywords

Cardiac magnetic resonance imaging; Endomyocardial biopsy; HFpEF; MCpEF; Myocarditis; Speckle tracking echocardiography

Indexed keywords

GADOLINIUM PENTETATE MEGLUMINE;

ADULT; ARTICLE; CARDIOVASCULAR MAGNETIC RESONANCE; CHRONIC MYOCARDITIS WITH PRESERVED LEFT VENTRICULAR EJECTION FRACTION; CLINICAL ARTICLE; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC TEST ACCURACY STUDY; FEMALE; HEART LEFT VENTRICLE EJECTION FRACTION; HEART MUSCLE BIOPSY; HEMODYNAMIC PARAMETERS; HUMAN; HUMAN TISSUE; LEFT VENTRICULAR GLOBAL LONGITUDINAL SYSTOLIC STRAIN; MALE; MULTIMODAL IMAGING; MYOCARDITIS; NUCLEAR MAGNETIC RESONANCE SCANNER; PREDICTIVE VALUE; PRIORITY JOURNAL; REAL TIME ULTRASOUND SCANNER; SENSITIVITY AND SPECIFICITY; TISSUE DOPPLER IMAGING; TWO DIMENSIONAL SPECKLE TRACKING ECHOCARDIOGRAPHY; CHRONIC DISEASE; COHORT ANALYSIS; DIAGNOSTIC IMAGING; ECHOCARDIOGRAPHY; HEART LEFT VENTRICLE FUNCTION; HEART STROKE VOLUME; MIDDLE AGED; PATHOPHYSIOLOGY; PHYSIOLOGY; PROCEDURES;

ADULT; CHRONIC DISEASE; COHORT STUDIES; ECHOCARDIOGRAPHY; FEMALE; HUMANS; MALE; MIDDLE AGED; MULTIMODAL IMAGING; MYOCARDITIS; STROKE VOLUME; VENTRICULAR FUNCTION, LEFT;

EID: 85019867381     PISSN: 01675273     EISSN: 18741754     Source Type: Journal    
DOI: 10.1016/j.ijcard.2017.05.038     Document Type: Article

References (45)

1. Caforio, A.L., Pankuweit, S., Arbustini, E., Basso, C., Gimeno-Blanes, J., Felix, S.B., European Society of Cardiology Working Group on Myocardial and Pericardial Diseases, et al. Current state of knowledge on aetiology, diagnosis, management, and therapy of myocarditis: a position statement of the European Society of Cardiology Working Group on Myocardial and Pericardial Diseases. Eur. Heart J. 34 (2013), 2636–2648.
2. Dominguez, F., Kühl, U., Pieske, B., Garcia-Pavia, P., Tschöpe, C., Update on myocarditis and inflammatory cardiomyopathy: reemergence of endomyocardial biopsy. Rev. Esp. Cardiol. (Engl. Ed.) 69 (2016), 178–187.
3. Tschöpe, C., Bock, C.T., Kasner, M., Noutsias, M., Westermann, D., Schwimmbeck, P.L., et al. High prevalence of cardiac parvovirus B19 infection in patients with isolated left ventricular diastolic dysfunction. Circulation 22:111 (2005), 879–886.
4. Noutsias, M., Myocarditis. Maisel, A.S., Filippatos, G., (eds.) Algorithms in Heart Failure, vol. 1, 2016, Jaypee Brothers Medical Publishers (P) Ltd, New Delhi, India, 323–345.
5. Escher, F., Westermann, D., Gaub, R., Pronk, J., Bock, T., Al-Saadi, N., et al. Development of diastolic heart failure in a 6-year follow-up study in patients after acute myocarditis. Heart 97:9 (2011), 709–714.
6. Escher, F., Kühl, U., Lassner, D., Poller, W., Westermann, D., Pieske, B., et al. Long-term outcome of patients with virus-negative chronic myocarditis or inflammatory cardiomyopathy after immunosuppressive therapy. Clin. Res. Cardiol. 105:12 (2016), 1011–1020.
7. Abdel-Aty, H., Boyé, P., Zagrosek, A., Wassmuth, R., Kumar, A., Messroghli, D., et al. Diagnostic performance of cardiovascular magnetic resonance in patients with suspected acute myocarditis. J. Am. Coll. Cardiol. 45 (2005), 1815–1822.
8. Gutberlet, M., Spors, B., Thoma, T., Bertram, H., Denecke, T., Felix, R., et al. Suspected chronic myocarditis at cardiac MR: diagnostic accuracy and association with immunohistologically detected inflammation and viral persistence. Radiology 246 (2008), 401–409.
9. Zagrosek, A., Abdel-Aty, H., Boyé, P., Wassmuth, R., Messroghli, D., Utz, W., et al. Cardiac magnetic resonance monitors reversible and irreversible myocardial injury in myocarditis. JACC Cardiovasc. Imaging 2 (2009), 131–138.
10. Mangin, M., Mahrholdt, H., Sechtem, U., Diagnosis of myocarditis: description and assessment of available methods. Dtsch. Med. Wochenschr. 131 (2006), 1228–1234.
11. Mahrholdt, H., Goedecke, C., Wagner, A., Meinhardt, G., Athanasiadis, A., Vogelsberg, H., et al. Cardiovascular magnetic resonance assessment of human myocarditis. Circulation 109 (2004), 1250–1258.
12. Friedrich, M.G., Sechtem, U., Schulz-Menger, J., Holmvang, G., Alakija, P., Cooper, L.T., International Consensus Group on Cardiovascular Magnetic Resonance in Myocarditis, et al. Cardiovascular magnetic resonance in myocarditis: a JACC white paper. J. Am. Coll. Cardiol. 53 (2009), 1475–1487.
13. Laissy, J.P., Messin, B., Varenne, O., Iung, B., Karila-Cohen, D., Schouman-Claeys, E., et al. MRI of acute myocarditis—a comprehensive approach based on various imaging sequences. Chest 122 (2002), 1638–1649.
14. Gahide, G., Bertrand, D., Roubille, F., Tron, C., Skaik, S., Piot, C., et al. MR delayed enhancement imaging findings in suspected acute myocarditis. Eur. Radiol. 20 (2010), 65–72.
15. Lurz, P., Eitel, I., Adam, J., Steiner, J., Grothoff, M., Desch, S., et al. Diagnostic performance of CMR imaging compared with EMB in patients with suspected myocarditis. J. Am. Coll. Cardiol. Img. 5 (2012), 513–524.
16. Röttgen, R., Christiani, R., Freyhardt, P., Gutberlet, M., Schultheiss, H.P., Hamm, B., et al. Magnetic resonance imaging findings in acute myocarditis and correlation with immunohistological parameters. Eur. Radiol. 21:6 (2011), 1259–1266.
17. Kasner, M., Gaub, R., Sinning, D., Westermann, D., Steendijk, P., Hoffmann, W., et al. Global strain rate imaging for the estimation of diastolic function in HFNEF compared with pressure-volume loop analysis. Eur. J. Echocardiogr. 11:9 (2010), 743–751.
18. Dandel, M., Hetzer, R., Echocardiographic strain and strain rate imaging-clinical applications. Int. J. Cardiol. 132:1 (2009), 11–24.
19. Blessberger, H., Binder, T., Two dimensional speckle tracking echocardiography: clinical applications. Heart 96:24 (2010), 2032–2040.
20. Mondillo, S., Galderisi, M., Mele, D., Cameli, M., Lomoriello, V.S., Zacà, V., Echocardiography Study Group of the Italian Society of Cardiology (Rome, Italy), et al. Speckle-tracking echocardiography: a new technique for assessing myocardial function. J. Ultrasound Med. 30:1 (2011), 71–83.
21. Serri, K., Reant, P., Lafitte, M., Berhouet, M., Le Bouffos, V., Roudaut, R., et al. Global and regional myocardial function quantification by two-dimensional strain: application in hypertrophic cardiomyopathy. J. Am. Coll. Cardiol. 47:6 (2006 Mar 21), 1175–1181.
22. Tschöpe, C., Kherad, B., Schultheiss, H.P., How to perform an endomyocardial biopsy?. Turk Kardiyol. Dern. Ars. 43 (2015), 572–575.
23. Noutsias, M., Seeberg, B., Schultheiss, H.P., Kühl, U., Expression of cell adhesion molecules in dilated cardiomyopathy: evidence for endothelial activation in inflammatory cardiomyopathy. Circulation 99:16 (1999), 2124–2131.
24. Noutsias, M., Pauschinger, M., Ostermann, K., Escher, F., Blohm, J.H., Schultheiss, H., et al. Digital image analysis system for quantification of infiltrates and cell adhesion molecules in inflammatory cardiomyopathy. Med. Sci. Monit. 8 (2002), MT59–MT71.
25. Kühl, U., Pauschinger, M., Seeberg, B., Lassner, D., Noutsias, M., Poller, W., et al. Viral persistence in the myocardium is associated with progressive cardiac dysfunction. Circulation 112 (2005), 1965–1970.
26. Paulus, W.J., Tschöpe, C., Sanderson, J.E., Rusconi, C., Flachskampf, F.A., Rademakers, F.E., et al. How to diagnose diastolic heart failure: a consecutive statement on the diagnosis of heart failure with normal left ventricular ejection fraction by the Heart Failure and Echocardiography Associations of the European Society of Cardiology. Eur. Heart J. 28 (2007), 2539–2550.
27. Kasner, M., Westermann, D., Steendijk, P., Gaub, R., Wilkenshoff, U., Weitmann, K., et al. Utility of Doppler echocardiography and tissue Doppler imaging in the estimation of diastolic function in heart failure with normal ejection fraction: a comparative Doppler-conductance catheterization study. Circulation 116 (2007), 637–647.
28. Pinto, Y.M., Elliott, P.M., Arbustini, E., Adler, Y., Anastasakis, A., Bohm, M., et al. Proposal for a revised definition of dilated cardiomyopathy, hypokinetic non-dilated cardiomyopathy, and its implications for clinical practice: a position statement of the ESC Working Group on Myocardial and Pericardial Diseases. Eur. Heart J. 37 (2016), 1850–1858.
29. Morimoto, S., Kato, S., Hiramitsu, S., Uemura, A., Ohtsuki, M., Kato, Y., et al. Narrowing of the left ventricular cavity associated with transient ventricular wall thickening reduces stroke volume in patients with acute myocarditis. Circ. J. 67 (2003), 490–494.
30. Schultz, J.C., Hilliard, A.A., Cooper, L.T. Jr., Rihal, C.S., Diagnosis and treatment of viral myocarditis. Mayo Clin. Proc. 84:11 (2009), 100–1009.
31. Felker, G.M., Boehmer, J.P., Hruban, R.H., Hutchins, G.M., Kasper, E.K., Baughman, K.L., et al. Echocardiographic findings in fulminant and acute myocarditis. J. Am. Coll. Cardiol. 36:1 (2000), 227–232.
32. Begieneman, M.P., Emmens, R.W., Rijvers, L., Kubat, B., Paulus, W.J., Vonk, A.B., et al. Ventricular myocarditis coincides with atrial myocarditis in patients. Cardiovasc. Pathol. 25 (2016), 141–148.
33. Gorcsan, J. 3rd, Tanaka, H., Echocardiographic assessment of myocardial strain. J. Am. Coll. Cardiol. 58 (2011), 1401–1413.
34. Koyama, J., Ray-Sequin, P.A., Falk, R.H., Longitudinal myocardial function assessed by tissue velocity, strain, and strain rate tissue Doppler echocardiography in patients with AL (primary) cardiac amyloidosis. Circulation 107 (2003), 2446–2452.
35. Prakasa, K.R., Wang, J., Tandri, H., Dalal, D., Bomma, C., Chojnowski, R., et al. Utility of tissue Doppler and strain echocardiography in arrhythmogenic right ventricular dysplasia/cardiomyopathy. Am. J. Cardiol. 100 (2007), 507–512.
36. Yajima, R., Kataoka, A., Takahashi, A., Uehara, M., Saito, M., Yamaguchi, C., et al. Distinguishing focal fibrotic lesions and non-fibrotic lesions in hypertrophic cardiomyopathy by assessment of regional myocardial strain using two-dimensional speckle tracking echocardiography: comparison with multislice CT. Int. J. Cardiol. 158:3 (2012), 423–432.
37. Geyer, H., Caracciolo, G., Abe, H., Wilansky, S., Carerj, S., Gentile, F., et al. Assessment of myocardial mechanics using speckle tracking echocardiogrpahy: fundamentals and clinical applications. J. Am. Soc. Echocardiogr. 23:4 (2010), 351–369.
38. Cooper, L.T., Baughman, K.L., Feldman, A.M., Frustaci, A., Jessup, M., Kühl, U., et al. The role of endomyocardial biopsy in the management of cardiovascular disease: a scientific statement from the American Heart Association, the American College of Cardiology, and the European Society of Cardiology endorsed by the Heart Failure Society of America and the Heart Failure Association of the European Society of Cardiology. Eur. Heart J. 28 (2007), 3076–3093.
39. Hsiao, J.F., Koshino, Y., Bonnichsen, C.R., Yu, Y., Miller, F.A. Jr., Pellikka, P.A., et al. Speckle tracking echocardiography in acute myocarditis. Int. J. Cardiovasc. Imaging 29 (2013), 275–284.
40. Di Bella, G., Gaeta, M., Pingitore, A., Oreto, G., Zito, C., Minutoli, F., et al. Myocardial deformation in acute myocarditis with normal left ventricular ejection wall motion — a cardiac magnetic resonance and 2-dimensional strain echocardiography study. Circ. J. 74 (2010), 1205–1213.
41. Kasner, M., Sinning, D., Escher, F., Lassner, D., Kühl, U., Schultheiss, H.P., et al. The utility of speckle tracking imaging in the diagnostic of acute myocarditis, as proven by endomyocardial biopsy. Int. J. Cardiol. 168:3 (2013), 3023–3024.
42. Lurz, P., Luecke, L., Eitel, I., Föhrenbach, F., Frank, C., Grothoff, M., et al. Comprehensive cardiac magnetic resonance imaging in patients with suspected myocarditis. The Mayo-Racer-Tail. J. Am. Coll. Cardiol. 67 (2016), 1800–1811.
43. Hinojar, R., Foote, L., Arroyo Ucar, E., Jackson, T., Jabbour, A., Yu, C.Y., et al. Native T1 in discrimination of acute and convalescent stages in patients with clinical diagnosis of myocarditis: a proposed diagnostic algorithm using CMR. JACC Cardiovasc. Imaging 8 (2015), 37–46.
44. Stampehl, M.R., Mann, D.L., Nguyen, J.S., Cota, F., Colmenares, C., Dokainish, H., Speckle strain echocardiography predicts outcome in patients with heart failure with both depressed and preserved left ventricular ejection fraction. Echocardiography 32 (2015), 71–78.
45. Shah, A.M., Claggett, B., Sweitzer, N.K., Shah, S.J., Anand, I.S., Liu, L., et al. Prognostic importance of impaired systolic function in heart failure with preserved ejection fraction and the impact of spironolactone. Circulation 132 (2015), 402–414.