메뉴 건너뛰기




Volumn 12, Issue 5, 2017, Pages

Development of a versatile oncolytic virus platform for local intra-tumoural expression of therapeutic transgenes

Author keywords

[No Author keywords available]

Indexed keywords

ENADENOTUCIREV; NG 285 ONCOLYTIC VIRUS; NG 61 ONCOLYTIC VIRUS; ONCOLYTIC VIRUS; UNCLASSIFIED DRUG; VASCULOTROPIN ANTIBODY;

EID: 85019381089     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0177810     Document Type: Article
Times cited : (23)

References (42)
  • 1
    • 84933586864 scopus 로고    scopus 로고
    • Talimogene Laherparepvec Improves Durable Response Rate in Patients With Advanced Melanoma
    • PMID: 26014293
    • Andtbacka RH, Kaufman HL, Collichio F, Amatruda T, Senzer N, Chesney J, et al. Talimogene Laherparepvec Improves Durable Response Rate in Patients With Advanced Melanoma. J Clin Oncol. 2015; 33(25):2780-8. https://doi.org/10.1200/JCO.2014.58.3377 PMID: 26014293
    • (2015) J Clin Oncol , vol.33 , Issue.25 , pp. 2780-2788
    • Andtbacka, R.H.1    Kaufman, H.L.2    Collichio, F.3    Amatruda, T.4    Senzer, N.5    Chesney, J.6
  • 2
    • 84952985128 scopus 로고    scopus 로고
    • Talimogene Laherparepvec: First Global Approval
    • PMID: 26620366
    • Greig SL. Talimogene Laherparepvec: First Global Approval. Drugs. 2016; 76(1):147-54. https://doi.org/10.1007/s40265-015-0522-7 PMID: 26620366
    • (2016) Drugs , vol.76 , Issue.1 , pp. 147-154
    • Greig, S.L.1
  • 4
    • 84959440182 scopus 로고    scopus 로고
    • Trial Watch-Oncolytic viruses and cancer therapy
    • PubMed Central PMCID: PMCPMC4801444. PMID: 27057469
    • Pol J, Buque A, Aranda F, Bloy N, Cremer I, Eggermont A, et al. Trial Watch-Oncolytic viruses and cancer therapy. Oncoimmunology. 2016; 5(2):e1117740. PubMed Central PMCID: PMCPMC4801444. https://doi.org/10.1080/2162402X.2015.1117740 PMID: 27057469
    • (2016) Oncoimmunology , vol.5 , Issue.2 , pp. e1117740
    • Pol, J.1    Buque, A.2    Aranda, F.3    Bloy, N.4    Cremer, I.5    Eggermont, A.6
  • 5
    • 84982958685 scopus 로고    scopus 로고
    • Oncolytic viruses-immunotherapeutics on the rise
    • Berl
    • Keller BA, Bell JC. Oncolytic viruses-immunotherapeutics on the rise. J Mol Med (Berl). 2016.
    • (2016) J Mol Med
    • Keller, B.A.1    Bell, J.C.2
  • 6
    • 33947245441 scopus 로고    scopus 로고
    • History of oncolytic viruses: Genesis to genetic engineering
    • PMID: 17299401
    • Kelly E, Russell SJ. History of oncolytic viruses: genesis to genetic engineering. Mol Ther. 2007; 15(4):651-9. https://doi.org/10.1038/sj.mt.6300108 PMID: 17299401
    • (2007) Mol Ther , vol.15 , Issue.4 , pp. 651-659
    • Kelly, E.1    Russell, S.J.2
  • 7
    • 84904999549 scopus 로고    scopus 로고
    • Going viral with cancer immunotherapy
    • PMID: 24990523
    • Lichty BD, Breitbach CJ, Stojdl DF, Bell JC. Going viral with cancer immunotherapy. Nat Rev Cancer. 2014; 14(8):559-67. https://doi.org/10.1038/nrc3770 PMID: 24990523
    • (2014) Nat Rev Cancer , vol.14 , Issue.8 , pp. 559-567
    • Lichty, B.D.1    Breitbach, C.J.2    Stojdl, D.F.3    Bell, J.C.4
  • 8
    • 84897476768 scopus 로고    scopus 로고
    • Localized oncolytic virotherapy overcomes systemic tumor resistance to immune checkpoint blockade immunotherapy
    • PubMed Central PMCID: PMCPMC4106918. PMID: 24598590
    • Zamarin D, Holmgaard RB, Subudhi SK, Park JS, Mansour M, Palese P, et al. Localized oncolytic virotherapy overcomes systemic tumor resistance to immune checkpoint blockade immunotherapy. Sci Transl Med. 2014; 6(226):226ra32. PubMed Central PMCID: PMCPMC4106918. https://doi.org/10.1126/scitranslmed.3008095 PMID: 24598590
    • (2014) Sci Transl Med , vol.6 , Issue.226 , pp. 226ra32
    • Zamarin, D.1    Holmgaard, R.B.2    Subudhi, S.K.3    Park, J.S.4    Mansour, M.5    Palese, P.6
  • 9
    • 84891825541 scopus 로고    scopus 로고
    • Immunogenic HSV-mediated oncolysis shapes the antitumor immune response and contributes to therapeutic efficacy
    • PubMed Central PMCID: PMCPMC3978812. PMID: 24343053
    • Workenhe ST, Simmons G, Pol JG, Lichty BD, Halford WP, Mossman KL. Immunogenic HSV-mediated oncolysis shapes the antitumor immune response and contributes to therapeutic efficacy. Mol Ther. 2014; 22(1):123-31. PubMed Central PMCID: PMCPMC3978812. https://doi.org/10.1038/mt.2013.238 PMID: 24343053
    • (2014) Mol Ther , vol.22 , Issue.1 , pp. 123-131
    • Workenhe, S.T.1    Simmons, G.2    Pol, J.G.3    Lichty, B.D.4    Halford, W.P.5    Mossman, K.L.6
  • 10
    • 85019370222 scopus 로고    scopus 로고
    • The efficacy of oncolytic adenovirus is mediated by T cell responses against virus and tumor in Syrian hamster model
    • Wang S, Li X, Wang P, Li H, Du X, Liu M, et al. The efficacy of oncolytic adenovirus is mediated by T cell responses against virus and tumor in Syrian hamster model. Clin Cancer Res. 2016.
    • (2016) Clin Cancer Res
    • Wang, S.1    Li, X.2    Wang, P.3    Li, H.4    Du, X.5    Liu, M.6
  • 11
    • 84962025382 scopus 로고    scopus 로고
    • Adenovirus Improves the Efficacy of Adoptive T-cell Therapy by Recruiting Immune Cells to and Promoting Their Activity at the Tumor
    • PMID: 25977260
    • Tahtinen S, Gronberg-Vaha-Koskela S, Lumen D, Merisalo-Soikkeli M, Siurala M, Airaksinen AJ, et al. Adenovirus Improves the Efficacy of Adoptive T-cell Therapy by Recruiting Immune Cells to and Promoting Their Activity at the Tumor. Cancer Immunol Res. 2015; 3(8):915-25. https://doi.org/10.1158/2326-6066.CIR-14-0220-T PMID: 25977260
    • (2015) Cancer Immunol Res , vol.3 , Issue.8 , pp. 915-925
    • Tahtinen, S.1    Gronberg-Vaha-Koskela, S.2    Lumen, D.3    Merisalo-Soikkeli, M.4    Siurala, M.5    Airaksinen, A.J.6
  • 12
    • 77149141965 scopus 로고    scopus 로고
    • Local and distant immunity induced by intralesional vaccination with an oncolytic herpes virus encoding GM-CSF in patients with stage IIIc and IV melanoma
    • PMID: 19915919
    • Kaufman HL, Kim DW, DeRaffele G, Mitcham J, Coffin RS, Kim-Schulze S. Local and distant immunity induced by intralesional vaccination with an oncolytic herpes virus encoding GM-CSF in patients with stage IIIc and IV melanoma. Ann Surg Oncol. 2010; 17(3):718-30. https://doi.org/10.1245/s10434-009-0809-6 PMID: 19915919
    • (2010) Ann Surg Oncol , vol.17 , Issue.3 , pp. 718-730
    • Kaufman, H.L.1    Kim, D.W.2    DeRaffele, G.3    Mitcham, J.4    Coffin, R.S.5    Kim-Schulze, S.6
  • 13
    • 84875225339 scopus 로고    scopus 로고
    • Randomized dose-finding clinical trial of oncolytic immunotherapeutic vaccinia JX-594 in liver cancer
    • PubMed Central PMCID: PMCPMC4268543. PMID: 23396206
    • Heo J, Reid T, Ruo L, Breitbach CJ, Rose S, Bloomston M, et al. Randomized dose-finding clinical trial of oncolytic immunotherapeutic vaccinia JX-594 in liver cancer. Nat Med. 2013; 19(3):329-36. PubMed Central PMCID: PMCPMC4268543. https://doi.org/10.1038/nm.3089 PMID: 23396206
    • (2013) Nat Med , vol.19 , Issue.3 , pp. 329-336
    • Heo, J.1    Reid, T.2    Ruo, L.3    Breitbach, C.J.4    Rose, S.5    Bloomston, M.6
  • 14
    • 84880706152 scopus 로고    scopus 로고
    • Oncology meets immunology: The cancer-immunity cycle
    • PMID: 23890059
    • Chen DS, Mellman I. Oncology meets immunology: the cancer-immunity cycle. Immunity. 2013; 39(1):1-10. https://doi.org/10.1016/j.immuni.2013.07.012 PMID: 23890059
    • (2013) Immunity , vol.39 , Issue.1 , pp. 1-10
    • Chen, D.S.1    Mellman, I.2
  • 15
    • 84960366855 scopus 로고    scopus 로고
    • Development of immuno-oncology drugs - From CTLA4 to PD1 to the next generations
    • PMID: 26965203
    • Hoos A. Development of immuno-oncology drugs - from CTLA4 to PD1 to the next generations. Nat Rev Drug Discov. 2016; 15(4):235-47. https://doi.org/10.1038/nrd.2015.35 PMID: 26965203
    • (2016) Nat Rev Drug Discov , vol.15 , Issue.4 , pp. 235-247
    • Hoos, A.1
  • 16
    • 84890814629 scopus 로고    scopus 로고
    • Breakthrough of the year 2013. Cancer immunotherapy
    • PMID: 24357284
    • Couzin-Frankel J. Breakthrough of the year 2013. Cancer immunotherapy. Science. 2013; 342(6165):1432-3. https://doi.org/10.1126/science.342.6165.1432 PMID: 24357284
    • (2013) Science , vol.342 , Issue.6165 , pp. 1432-1433
    • Couzin-Frankel, J.1
  • 17
    • 84976294109 scopus 로고    scopus 로고
    • Pembrolizumab for the treatment of advanced melanoma
    • PubMed Central PMCID: PMCPMC5010088. PMID: 27597930
    • Burns MC, O'Donnell A, Puzanov I. Pembrolizumab for the treatment of advanced melanoma. Expert Opin Orphan Drugs. 2016; 4(8):867-73. PubMed Central PMCID: PMCPMC5010088. https://doi.org/10.1080/21678707.2016.1191348 PMID: 27597930
    • (2016) Expert Opin Orphan Drugs , vol.4 , Issue.8 , pp. 867-873
    • Burns, M.C.1    O'Donnell, A.2    Puzanov, I.3
  • 18
    • 84955753458 scopus 로고    scopus 로고
    • Melanoma in 2015: Immune-checkpoint blockade - Durable cancer control
    • PMID: 26787285
    • Buchbinder EI, Hodi FS. Melanoma in 2015: Immune-checkpoint blockade - durable cancer control. Nat Rev Clin Oncol. 2016; 13(2):77-8. https://doi.org/10.1038/nrclinonc.2015.237 PMID: 26787285
    • (2016) Nat Rev Clin Oncol , vol.13 , Issue.2 , pp. 77-78
    • Buchbinder, E.I.1    Hodi, F.S.2
  • 19
    • 84962038946 scopus 로고    scopus 로고
    • Atezolizumab versus docetaxel for patients with previously treated non-small-cell lung cancer (POPLAR): A multicentre, open-label, phase 2 randomised controlled trial
    • PMID: 26970723
    • Fehrenbacher L, Spira A, Ballinger M, Kowanetz M, Vansteenkiste J, Mazieres J, et al. Atezolizumab versus docetaxel for patients with previously treated non-small-cell lung cancer (POPLAR): a multicentre, open-label, phase 2 randomised controlled trial. Lancet. 2016; 387(10030):1837-46. https://doi.org/10.1016/S0140-6736(16)00587-0 PMID: 26970723
    • (2016) Lancet , vol.387 , Issue.10030 , pp. 1837-1846
    • Fehrenbacher, L.1    Spira, A.2    Ballinger, M.3    Kowanetz, M.4    Vansteenkiste, J.5    Mazieres, J.6
  • 20
    • 84936147067 scopus 로고    scopus 로고
    • Combined Nivolumab and Ipilimumab or Monotherapy in Untreated Melanoma
    • PMID: 26027431
    • Larkin J, Chiarion-Sileni V, Gonzalez R, Grob JJ, Cowey CL, Lao CD, et al. Combined Nivolumab and Ipilimumab or Monotherapy in Untreated Melanoma. N Engl J Med. 2015; 373(1):23-34. https://doi.org/10.1056/NEJMoa1504030 PMID: 26027431
    • (2015) N Engl J Med , vol.373 , Issue.1 , pp. 23-34
    • Larkin, J.1    Chiarion-Sileni, V.2    Gonzalez, R.3    Grob, J.J.4    Cowey, C.L.5    Lao, C.D.6
  • 21
    • 85015467210 scopus 로고    scopus 로고
    • Immune checkpoint inhibitors: Therapeutic advances in melanoma
    • PubMed Central PMCID: PMCPMC4630549. PMID: 26605313
    • Marquez-Rodas I, Cerezuela P, Soria A, Berrocal A, Riso A, Gonzalez-Cao M, et al. Immune checkpoint inhibitors: therapeutic advances in melanoma. Ann Transl Med. 2015; 3(18):267. PubMed Central PMCID: PMCPMC4630549. https://doi.org/10.3978/j.issn.2305-5839.2015.10.27 PMID: 26605313
    • (2015) Ann Transl Med , vol.3 , Issue.18 , pp. 267
    • Marquez-Rodas, I.1    Cerezuela, P.2    Soria, A.3    Berrocal, A.4    Riso, A.5    Gonzalez-Cao, M.6
  • 22
    • 84929481482 scopus 로고    scopus 로고
    • Nivolumab and ipilimumab versus ipilimumab in untreated melanoma
    • PMID: 25891304
    • Postow MA, Chesney J, Pavlick AC, Robert C, Grossmann K, McDermott D, et al. Nivolumab and ipilimumab versus ipilimumab in untreated melanoma. N Engl J Med. 2015; 372(21):2006-17. https://doi.org/10.1056/NEJMoa1414428 PMID: 25891304
    • (2015) N Engl J Med , vol.372 , Issue.21 , pp. 2006-2017
    • Postow, M.A.1    Chesney, J.2    Pavlick, A.C.3    Robert, C.4    Grossmann, K.5    McDermott, D.6
  • 23
    • 84929481481 scopus 로고    scopus 로고
    • Pembrolizumab versus Ipilimumab in Advanced Melanoma
    • PMID: 25891173
    • Robert C, Schachter J, Long GV, Arance A, Grob JJ, Mortier L, et al. Pembrolizumab versus Ipilimumab in Advanced Melanoma. N Engl J Med. 2015; 372(26):2521-32. https://doi.org/10.1056/NEJMoa1503093 PMID: 25891173
    • (2015) N Engl J Med , vol.372 , Issue.26 , pp. 2521-2532
    • Robert, C.1    Schachter, J.2    Long, G.V.3    Arance, A.4    Grob, J.J.5    Mortier, L.6
  • 24
    • 85011542577 scopus 로고    scopus 로고
    • Combined nivolumab and ipilimumab versus ipilimumab alone in patients with advanced melanoma: 2-Year overall survival outcomes in a multicentre, randomised, controlled, phase 2 trial
    • Hodi FS, Chesney J, Pavlick AC, Robert C, Grossmann KF, McDermott DF, et al. Combined nivolumab and ipilimumab versus ipilimumab alone in patients with advanced melanoma: 2-year overall survival outcomes in a multicentre, randomised, controlled, phase 2 trial. Lancet Oncol. 2016.
    • (2016) Lancet Oncol
    • Hodi, F.S.1    Chesney, J.2    Pavlick, A.C.3    Robert, C.4    Grossmann, K.F.5    McDermott, D.F.6
  • 25
    • 84988974344 scopus 로고    scopus 로고
    • Immune-Related Adverse Events From Immune Checkpoint Inhibitors
    • PMID: 27170616
    • Marrone KA, Ying W, Naidoo J. Immune-Related Adverse Events From Immune Checkpoint Inhibitors. Clin Pharmacol Ther. 2016; 100(3):242-51. https://doi.org/10.1002/cpt.394 PMID: 27170616
    • (2016) Clin Pharmacol Ther , vol.100 , Issue.3 , pp. 242-251
    • Marrone, K.A.1    Ying, W.2    Naidoo, J.3
  • 26
    • 84953309212 scopus 로고    scopus 로고
    • Immune-related adverse events with immune checkpoint blockade: A comprehensive review
    • PMID: 26765102
    • Michot JM, Bigenwald C, Champiat S, Collins M, Carbonnel F, Postel-Vinay S, et al. Immune-related adverse events with immune checkpoint blockade: a comprehensive review. Eur J Cancer. 2016; 54:139-48. https://doi.org/10.1016/j.ejca.2015.11.016 PMID: 26765102
    • (2016) Eur J Cancer , vol.54 , pp. 139-148
    • Michot, J.M.1    Bigenwald, C.2    Champiat, S.3    Collins, M.4    Carbonnel, F.5    Postel-Vinay, S.6
  • 27
    • 84973644391 scopus 로고    scopus 로고
    • Economic sustainability of anti-PD-1 agents nivolumab and pembrolizumab in cancer patients: Recent insights and future challenges
    • PMID: 27310708
    • Tartari F, Santoni M, Burattini L, Mazzanti P, Onofri A, Berardi R. Economic sustainability of anti-PD-1 agents nivolumab and pembrolizumab in cancer patients: Recent insights and future challenges. Cancer Treat Rev. 2016; 48:20-4. https://doi.org/10.1016/j.ctrv.2016.06.002 PMID: 27310708
    • (2016) Cancer Treat Rev , vol.48 , pp. 20-24
    • Tartari, F.1    Santoni, M.2    Burattini, L.3    Mazzanti, P.4    Onofri, A.5    Berardi, R.6
  • 28
    • 61849089262 scopus 로고    scopus 로고
    • Human erythrocytes bind and inactivate type 5 adenovirus by presenting Coxsackie virus-adenovirus receptor and complement receptor 1
    • PubMed Central PMCID: PMCPMC2651010. PMID: 19131551
    • Carlisle RC, Di Y, Cerny AM, Sonnen AF, Sim RB, Green NK, et al. Human erythrocytes bind and inactivate type 5 adenovirus by presenting Coxsackie virus-adenovirus receptor and complement receptor 1. Blood. 2009; 113(9):1909-18. PubMed Central PMCID: PMCPMC2651010. https://doi.org/10.1182/blood-2008-09-178459 PMID: 19131551
    • (2009) Blood , vol.113 , Issue.9 , pp. 1909-1918
    • Carlisle, R.C.1    Di, Y.2    Cerny, A.M.3    Sonnen, A.F.4    Sim, R.B.5    Green, N.K.6
  • 29
    • 33747519945 scopus 로고    scopus 로고
    • Striking out at disseminated metastases: The systemic delivery of oncolytic viruses
    • PMID: 16955693
    • Fisher K. Striking out at disseminated metastases: the systemic delivery of oncolytic viruses. Curr Opin Mol Ther. 2006; 8(4):301-13. PMID: 16955693
    • (2006) Curr Opin Mol Ther , vol.8 , Issue.4 , pp. 301-313
    • Fisher, K.1
  • 30
    • 49149090311 scopus 로고    scopus 로고
    • Directed evolution generates a novel oncolytic virus for the treatment of colon cancer
    • PubMed Central PMCID: PMCPMC2423470. PMID: 18560559
    • Kuhn I, Harden P, Bauzon M, Chartier C, Nye J, Thorne S, et al. Directed evolution generates a novel oncolytic virus for the treatment of colon cancer. PLoS One. 2008; 3(6):e2409. PubMed Central PMCID: PMCPMC2423470. https://doi.org/10.1371/journal.pone.0002409 PMID: 18560559
    • (2008) PLoS One , vol.3 , Issue.6
    • Kuhn, I.1    Harden, P.2    Bauzon, M.3    Chartier, C.4    Nye, J.5    Thorne, S.6
  • 31
    • 84897575156 scopus 로고    scopus 로고
    • Activity of a group B oncolytic adenovirus (ColoAd1) in whole human blood
    • PMID: 24553347
    • Di Y, Seymour L, Fisher K. Activity of a group B oncolytic adenovirus (ColoAd1) in whole human blood. Gene Ther. 2014; 21(4):440-3. https://doi.org/10.1038/gt.2014.2 PMID: 24553347
    • (2014) Gene Ther , vol.21 , Issue.4 , pp. 440-443
    • Di, Y.1    Seymour, L.2    Fisher, K.3
  • 32
    • 84963987806 scopus 로고    scopus 로고
    • A Phase I study of enadenotucirev, an onclytic Ad11/Ad3 chimeric group B adenovirus, administered intravenously - Analysis of dose expansion and repeat cycle cohorts n patients with metastatic colorectal cancer (mCRC)
    • Calvo E, Gil-Martin M, Cubillo A, Machiels J- P, Rottey S, Mardjuadi FI, et al. A Phase I study of enadenotucirev, an onclytic Ad11/Ad3 chimeric group B adenovirus, administered intravenously - analysis of dose expansion and repeat cycle cohorts n patients with metastatic colorectal cancer (mCRC). Annals of Oncology. 2014; 25(Suppl 4):iv367.
    • (2014) Annals of Oncology , vol.25 , pp. iv367
    • Calvo, E.1    Gil-Martin, M.2    Cubillo, A.3    Machiels, J.-P.4    Rottey, S.5    Mardjuadi, F.I.6
  • 33
  • 34
    • 0027260609 scopus 로고
    • Packaging capacity and stability of human adenovirus type 5 vectors
    • PubMed Central PMCID: PMCPMC238011. PMID: 8371349
    • Bett AJ, Prevec L, Graham FL. Packaging capacity and stability of human adenovirus type 5 vectors. J Virol. 1993; 67(10):5911-21. PubMed Central PMCID: PMCPMC238011. PMID: 8371349
    • (1993) J Virol , vol.67 , Issue.10 , pp. 5911-5921
    • Bett, A.J.1    Prevec, L.2    Graham, F.L.3
  • 35
    • 28444474772 scopus 로고    scopus 로고
    • Identification of novel insertion sites in the Ad5 genome that utilize the Ad splicing machinery for therapeutic gene expression
    • PMID: 16165398
    • Jin F, Kretschmer PJ, Hermiston TW. Identification of novel insertion sites in the Ad5 genome that utilize the Ad splicing machinery for therapeutic gene expression. Mol Ther. 2005; 12(6):1052-63. https://doi.org/10.1016/j.ymthe.2005.07.696 PMID: 16165398
    • (2005) Mol Ther , vol.12 , Issue.6 , pp. 1052-1063
    • Jin, F.1    Kretschmer, P.J.2    Hermiston, T.W.3
  • 37
    • 84937763318 scopus 로고    scopus 로고
    • Escape of non-enveloped virus from intact cells
    • PubMed Central PMCID: PMCPMC4440412
    • Bird SW, Kirkegaard K. Escape of non-enveloped virus from intact cells. Virology. 2015;479-480:444-9. PubMed Central PMCID: PMCPMC4440412.
    • (2015) Virology , vol.479-480 , pp. 444-449
    • Bird, S.W.1    Kirkegaard, K.2
  • 38
    • 84911100138 scopus 로고    scopus 로고
    • A first-in-class, first-in-human phase I study of enadenotucirev, an oncolytic Ad11/Ad3 chimeric group B adenovirus, administered intravenously in patients with metastatic epithelial tumours
    • Calvo E, Gil-Martin M, Machiels J-P, Rottey S, Cubillo A, Salazar R, et al. A first-in-class, first-in-human phase I study of enadenotucirev, an oncolytic Ad11/Ad3 chimeric group B adenovirus, administered intravenously in patients with metastatic epithelial tumours. J Clin Oncol. 2014; 32:5s:(suppl; abstr 3103).
    • (2014) J Clin Oncol , vol.32 , pp. 5s
    • Calvo, E.1    Gil-Martin, M.2    Machiels, J.-P.3    Rottey, S.4    Cubillo, A.5    Salazar, R.6
  • 39
    • 85019380522 scopus 로고    scopus 로고
    • A phase I/II studcy of Enadenotucirev, an oncolytic Ad11/Ad3 chimeric group B adenovirus, administered intraperitoneally (IP): Dose finding and proof of concept in platinum-resistant epthelial ovarian cancer
    • McNeish I, Agnieszka M, Twelves C, Glasspool R, Ajaz M, Morrison R, et al. A phase I/II studcy of Enadenotucirev, an oncolytic Ad11/Ad3 chimeric group B adenovirus, administered intraperitoneally (IP): Dose finding and proof of concept in platinum-resistant epthelial ovarian cancer. Journal of Clinical Oncology. 2015; 33(15-suppl):TPS5611.
    • (2015) Journal of Clinical Oncology , vol.33 , Issue.15 , pp. TPS5611
    • McNeish, I.1    Agnieszka, M.2    Twelves, C.3    Glasspool, R.4    Ajaz, M.5    Morrison, R.6
  • 40
    • 33845336115 scopus 로고    scopus 로고
    • A phase I study of OncoVEXGM-CSF, a second-generation oncolytic herpes simplex virus expressing granulocyte macrophage colony-stimulating factor
    • PMID: 17121894
    • Hu JC, Coffin RS, Davis CJ, Graham NJ, Groves N, Guest PJ, et al. A phase I study of OncoVEXGM-CSF, a second-generation oncolytic herpes simplex virus expressing granulocyte macrophage colony-stimulating factor. Clin Cancer Res. 2006; 12(22):6737-47. https://doi.org/10.1158/1078-0432.CCR-06-0759 PMID: 17121894
    • (2006) Clin Cancer Res , vol.12 , Issue.22 , pp. 6737-6747
    • Hu, J.C.1    Coffin, R.S.2    Davis, C.J.3    Graham, N.J.4    Groves, N.5    Guest, P.J.6
  • 42
    • 83455203483 scopus 로고    scopus 로고
    • Real-time PCR-based assay to quantify the relative amount of human and mouse tissue present in tumor xenografts
    • PubMed Central PMCID: PMCPMC3281124. PMID: 22176647
    • Alcoser SY, Kimmel DJ, Borgel SD, Carter JP, Dougherty KM, Hollingshead MG. Real-time PCR-based assay to quantify the relative amount of human and mouse tissue present in tumor xenografts. BMC Biotechnol. 2011; 11:124. PubMed Central PMCID: PMCPMC3281124. https://doi.org/10.1186/1472-6750-11-124 PMID: 22176647
    • (2011) BMC Biotechnol , vol.11 , pp. 124
    • Alcoser, S.Y.1    Kimmel, D.J.2    Borgel, S.D.3    Carter, J.P.4    Dougherty, K.M.5    Hollingshead, M.G.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.