A prospective study of the association between orthostatic hypotension and falls: Definition matters

Age and Ageing

Volumn 46, Issue 3, 2017, Pages 439-445

  McDonald, Claire ^a,c   Pearce, Mark ^b   Kerr, Simon R ^b,c   Newton, Julia ^b,c  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

^b NEWCASTLE UNIVERSITY   (United Kingdom)

^c NEWCASTLE UPON TYNE HOSPITALS NHS FOUNDATION TRUST   (United Kingdom)

Author keywords

Falls; Longitudinal; Older people; Orthostatic hypotension

Indexed keywords

AGED; ARTICLE; BODY MASS; CLINICAL ASSESSMENT; COHORT ANALYSIS; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; FALLING; FEMALE; FOLLOW UP; HUMAN; MALE; ORTHOSTATIC HYPOTENSION; PHOTOELECTRIC PLETHYSMOGRAPHY; POPULATION RESEARCH; PRIORITY JOURNAL; PROSPECTIVE STUDY; SYSTOLIC BLOOD PRESSURE; BLOOD PRESSURE; BLOOD PRESSURE MEASUREMENT; CHI SQUARE DISTRIBUTION; COMPARATIVE STUDY; ENGLAND; NOMENCLATURE; ODDS RATIO; PATHOPHYSIOLOGY; PREDICTIVE VALUE; PREVALENCE; PROCEDURES; PROPORTIONAL HAZARDS MODEL; REPRODUCIBILITY; RISK FACTOR; STATISTICAL MODEL;

ACCIDENTAL FALLS; AGED; BLOOD PRESSURE; BLOOD PRESSURE DETERMINATION; CHI-SQUARE DISTRIBUTION; ENGLAND; FEMALE; HUMANS; HYPOTENSION, ORTHOSTATIC; LOGISTIC MODELS; MALE; ODDS RATIO; PHOTOPLETHYSMOGRAPHY; PREDICTIVE VALUE OF TESTS; PREVALENCE; PROPORTIONAL HAZARDS MODELS; PROSPECTIVE STUDIES; REPRODUCIBILITY OF RESULTS; RISK FACTORS; TERMINOLOGY AS TOPIC;

EID: 85019256338     PISSN: 00020729     EISSN: 14682834     Source Type: Journal    
DOI: 10.1093/ageing/afw227     Document Type: Article

References (31)

1. Masud T, Morris RO. Epidemiology of falls. Age Ageing 2001; 30: 3-7.
2. Cwikel J, Fried AV. The social epidemiology of falls among community-dwelling elderly: guidelines for prevention. Disabil Rehabil 1992; 14: 113-21.
3. Davis JC, Robertson MC, Ashe MC, Liu-Ambrose T, Khan KM, Marra CA. International comparison of cost of falls in older adults living in the community: a systematic review. Osteoporos Int 2010; 21: 1295-306.
4. Amber H. AGS releases guideline for prevention of falls in older persons. Am Fam Physician 2010; 82: 81-2.
5. American Geriatrics Society BGS. AGS/BGS Clinical Practice Guideline: Prevention of Falls in Older Persons, New York, NY: American Geriatrics Society, 2010.
6. National Institute for Health and Care Excellence. Assessment and Prevention of Falls in Older People. London, 2013.
7. Chang JT, Morton SC, Rubenstein LZ et al. Interventions for the prevention of falls in older adults: systematic review and meta-analysis of randomised clinical trials. BMJ 2004; 328: 680.
8. Gillespie L. Preventing falls in elderly people. BMJ 2004; 328: 653-4.
9. Kario K, Tobin JN, Wolfson LI et al. Lower standing systolic blood pressure as a predictor of falls in the elderly: A community-based prospective study. J Am Coll Cardiol 2001; 38: 246-52.
10. Graafmans WC, Ooms ME, Hofstee HMA, Bezemer PD, Bouter LM, Lips P. Falls in the elderly: a prospective study of risk factors and risk profiles. Am J Epidemiol 1996; 143: 1129-36.
11. Ooi WL, Hossain M, Lipsitz LA. The association between orthostatic hypotension and recurrent falls in nursing home residents. Am J Med 2000; 108: 106-11.
12. McCarthy F, Fan CW, Kearney PM, Walsh C, Kenny RA. What is the evidence for cardiovascular disorders as a risk factor for non-syncopal falls? Scope for future research. Eur Geriatr Med 2010; 1: 244-51.
13. Frith J, Newton JL, Parry SW. Measuring and defining orthostatic hypotension in the older person. Age Ageing 2014; 43: 168-170.
14. Schatz IJ, Bannister R, Freeman RL et al. Consensus statement on the definition of orthostatic hypotension, pure autonomic failure, and multiple system atrophy. J Neurol Sci 1996; 144: 218-9.
15. Freeman R, Wieling W, Axelrod F et al. Consensus statement on the definition of orthostatic hypotension, neurally mediated syncope and the postural tachycardia syndrome. Clin Auton Res 2011; 21: 69-72.
16. Kerr SR, Pearce MS, Brayne C, Davis RJ, Kenny RA. Carotid sinus hypersensitivity in asymptomatic older persons: implications for diagnosis of syncope and falls. Adv Intern Med 2006; 166: 515-20.
17. Folstein MF, Folstein SE, McHugh PR. 'Mini-mental state'. A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 1975; 12: 189-98.
18. Tinetti ME. Performance-oriented assessment of mobility problems in elderly patients. J Am Geriatr Soc 1986; 34: 119-26.
19. Belmin J, Abderrhamane M, Medjahed S et al. Variability of blood pressure response to orthostatism and reproducibility of the diagnosis of orthostatic hypotension in elderly subjects. J Gerontol A Biol Sci Med Sci 2000; 55: M667-71.
20. Cooke J, Carew S, Quinn C et al. The prevalence and pathological correlates of orthostatic hypotension and its subtypes when measured using beat-to-beat technology in a sample of older adults living in the community. Age Ageing 2013; 42: 709-14.
21. Romero-Ortuno R, Cogan L, Foran T, Kenny RA, Fan CW. Continuous noninvasive orthostatic blood pressure measurements and their relationship with orthostatic intolerance, falls, and frailty in older people. J Am Geriatr Soc 2011; 59: 655-65.
22. Parry SW, Steen IN, Baptist M, Kenny RA. Amnesia for loss of consciousness in carotid sinus syndrome: implications for presentation with falls. J Am Coll Cardiol 2005; 45: 1840-3.
23. Davies AJ, Kenny RA. Falls presenting to the accident and emergency department: types of presentation and risk factor profile. Age Ageing 1996; 25: 362-6.
24. O'Dwyer C, Bennett K, Langan Y, Fan CW, Kenny RA. Amnesia for loss of consciousness is common in vasovagal syncope. Europace 2011; 13: 1040-5.
25. Pantoni L, Garcia JH. Pathogenesis of leukoaraiosis: a review. Stroke. 1997; 28: 652-9.
26. Zheng JJJ, Delbaere K, Close JCT, Sachdev PS, Lord SR. Impact of white matter lesions on physical functioning and fall risk in older people: a systematic review. Stroke 2011; 42: 2086-90.
27. van Beek AH, Claassen JA, Rikkert MG, Jansen RW. Cerebral autoregulation: an overview of current concepts and methodology with special focus on the elderly. J Cereb Blood Flow Metab 2008; 28: 1071-85.
28. Deandrea S, Lucenteforte E, Bravi F, Foschi R, La Vecchia C, Negri E. Risk factors for falls in community-dwelling older people: a systematic review and meta-analysis. Epidemiology 2010; 21: 658-68.
29. Woolcott JC, Richardson KJ, Wiens MO et al. Meta-analysis of the impact of 9 medication classes on falls in elderly persons. Arch Intern Med 2009; 169: 1952-60.
30. Muir SW, Gopaul K, Odasso MMM. The role of cognitive impairment in fall risk among older adults: a systematic review and meta-analysis. Age Ageing 2012; 41: 299-308.
31. Ward C, Kenny RA. Reproducibility of orthostatic hypotension in symptomatic elderly. Am J Med 1996; 100: 418-22.