In vivo modification of tRNA with an artificial nucleobase leads to full disease remission in an animal model of multiple sclerosis

Nucleic acids research

Volumn 45, Issue 4, 2017, Pages 2029-2039

  Varghese, Sreeja ^a   Cotter, Michelle ^a   Chevot, Franciane ^a   Fergus, Claire ^a   Cunningham, Colm ^a   Mills, Kingston H ^a   Connon, Stephen J ^a   Southern, John M ^a   Kelly, Vincent P ^a  

^a TRINITY COLLEGE DUBLIN   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOSYLTRANSFERASE; NPPDAG COMPOUND; PYRIMIDINONE DERIVATIVE; PYRROLE DERIVATIVE; QUEUINE TRNA-RIBOSYLTRANSFERASE; TIOGUANINE; TRANSFER RNA;

ANIMAL; BRAIN; C57BL MOUSE; CHEMISTRY; DISEASE MODEL; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; GENE THERAPY; GENETICS; METABOLISM; MULTIPLE SCLEROSIS; PATHOLOGY; PROCEDURES;

ANIMALS; BRAIN; DISEASE MODELS, ANIMAL; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; GENETIC THERAPY; MICE, INBRED C57BL; MULTIPLE SCLEROSIS; PENTOSYLTRANSFERASES; PYRIMIDINONES; PYRROLES; RNA, TRANSFER; THIOGUANINE;

EID: 85019208936     PISSN: None     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkw847     Document Type: Article

References (0)