Severe hypertension with renal thrombotic microangiopathy: what happened to the usual suspect?

Kidney International

Volumn 91, Issue 6, 2017, Pages 1271-1274

  Van Laecke, Steven ^a   Van Biesen, Wim ^a  

^a GHENT UNIVERSITY HOSPITAL   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSIN ANTAGONIST; ECULIZUMAB; RENIN INHIBITOR;

ALGORITHM; BLOOD PRESSURE REGULATION; CHRONIC KIDNEY FAILURE; COMPLEMENT ACTIVATION; DIASTOLIC BLOOD PRESSURE; DISEASE ASSOCIATION; DISEASE EXACERBATION; DISEASE SEVERITY; ENDOTHELIAL DYSFUNCTION; GENETIC VARIABILITY; HEMOLYTIC UREMIC SYNDROME; HUMAN; IMMUNOPATHOGENESIS; KIDNEY BIOPSY; KIDNEY DISEASE; KIDNEY DYSFUNCTION; MALIGNANT HYPERTENSION; MOLECULAR PATHOLOGY; NONHUMAN; NOTE; PATHOPHYSIOLOGY; PRACTICE GUIDELINE; PREECLAMPSIA; PRIORITY JOURNAL; RETINOPATHY; RISK FACTOR; SYSTEMIC DISEASE; SYSTOLIC BLOOD PRESSURE; THROMBOTIC THROMBOCYTOPENIC PURPURA; VASCULITIS; HYPERTENSION;

ATYPICAL HEMOLYTIC UREMIC SYNDROME; HUMANS; HYPERTENSION; THROMBOTIC MICROANGIOPATHIES;

EID: 85019135806     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1016/j.kint.2017.02.025     Document Type: Note

References (9)

1. Wenzel, U.O., Bode, M., Köhl, J., et al. A pathogenic role of complement in arterial hypertension and hypertensive organ damage. Am J Physiol Heart Circ Physiol 312 (2017), H349–H354.
2. Timmermans, S.A.M.E.G., Abdul-Hamid, M.A., Vanderlocht, J., et al. Patients with hypertension-associated thrombotic microangiopathy may present with complement abnormalities. Kidney Int 91 (2017), 1420–1425.
3. Goodship, T.H., Cook, H.T., Fakhouri, F., et al. Atypical haemolytic uremic syndrome and C3 glomerulopathy: conclusions from a “Kidney Disease: Improving Global Outcomes” (KDIGO) Controversies Conference. Kidney Int 91 (2017), 539–551.
4. Shavit, L., Reinus, C., Sotki, I., Severe renal failure and microangiopathic hemolysis induced by malignant hypertension-case series and review of literature. Clin Nephrol 73 (2010), 147–152.
5. Cremer, A., Amraoui, F., Lip, G.Y.H., et al. From malignant hypertension to hypertension-MOD: a modern definition for and old but still dangerous emergency. J Hum Hypertens 30 (2016), 463–466.
6. Van den Born, B.J., Honnebier, U.P., Koopmans, R.P., et al. Microangiopathic hemolysis and renal failure in malignant hypertension. Hypertension 42 (2005), 246–251.
7. Mathew, R.O., Nayer, A.I., Asif, A., The endothelium as the common denominator in malignant hypertension and thrombotic microangiopathy. J Am Soc Hypertens 10 (2016), 352–359.
8. Chua, J.S., Baelde, H.K., Zandbergen, M., et al. Complement factor C4d is a common denominator in thrombotic microangiopathy. J Am Soc Nephrol 26 (2015), 2239–2247.
9. Asif A, Nayer A, Haas CS. Atypical haemolytic uremic syndrome in the setting of complement-amplifying conditions: case reports and a review of the evidence for treatment with eculizumab [e-pub ahead of print]. J Nephrol. http://dx.doi.org/10.1007/s40620-016-0357-7. Accessed March 28, 2017.