Adherence to capecitabine in preoperative treatment of stage II and III rectal cancer: Do we need to worry?

Annals of Oncology

Volumn 28, Issue 4, 2017, Pages 831-835

  Font, R ^a   Espinas, J A ^a   Layos, L ^b   Martinez Villacampa, M ^b   Capdevila, J ^c   Tobena M ^d   Pisa, A ^e   Pericay, C ^f   Lezcano, C ^g   Fort, E ^h   Cardona, I ^c   Berga, N ^d   Sola J ^a   Borras, J M ^a,i  

^a Institute for Biomedical Research   (Spain)

^b CATALAN INSTITUTE OF ONCOLOGY   (Spain)

^c HOSPITAL UNIVERSITARI VALL D HEBRON   (Spain)

^d HOSPITAL DE LA SANTA CREU I SANT PAU   (Spain)

^e Brain   (Spain)

^f Neurology Section   (Spain)

^g HOSPITAL UNIVERSITARI GERMANS TRIAS I PUJOL   (Spain)

^h ICO L'Hospitalet   (Spain)

ⁱ UNIVERSITY OF BARCELONA   (Spain)

Author keywords

Adherence; HAD; Oral chemotherapy; Quality of life; Rectal cancer

Indexed keywords

CAPECITABINE; ANTINEOPLASTIC ANTIMETABOLITE;

ADJUVANT THERAPY; ADULT; AGED; ANAMNESIS; ANXIETY; ARTICLE; CANCER RADIOTHERAPY; CANCER STAGING; DEPRESSION; FEMALE; HOSPITAL ANXIETY AND DEPRESSION SCALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MEDICAL RECORD REVIEW; MIDDLE AGED; MULTICENTER STUDY; OBSERVATIONAL STUDY; PATIENT COMPLIANCE; PREOPERATIVE CARE; PRESCRIPTION; PRIORITY JOURNAL; PROSPECTIVE STUDY; QUALITY OF LIFE; QUESTIONNAIRE; RECTUM CANCER; RECTUM SURGERY; SELF REPORT; SPAIN; UNSPECIFIED SIDE EFFECT; ADJUVANT CHEMOTHERAPY; CLINICAL TRIAL; MEDICATION COMPLIANCE; NEOADJUVANT THERAPY; PROCEDURES; RECTAL NEOPLASMS; STATISTICS AND NUMERICAL DATA;

ADULT; AGED; ANTIMETABOLITES, ANTINEOPLASTIC; CAPECITABINE; CHEMOTHERAPY, ADJUVANT; FEMALE; HUMANS; MALE; MEDICATION ADHERENCE; MIDDLE AGED; NEOADJUVANT THERAPY; NEOPLASM STAGING; PROSPECTIVE STUDIES; RECTAL NEOPLASMS; SPAIN;

EID: 85019073356     PISSN: 09237534     EISSN: 15698041     Source Type: Journal    
DOI: 10.1093/annonc/mdx006     Document Type: Article

References (18)

1. Van de Velde CJH, Boolens P, Borras JM et al. EURECCA colorectal: multidisciplinary management: European consensus conference colon & rectum. Eur J Cancer 2014; 50: e1-e34.
2. Osterberg L, Blaschke T. Adherence to medication. N Engl J Med 2005; 353: 487-497.
3. Font R, Espinas JA, Gil-Gil M et al. Prescription refill, patient self-report and physician reporting assessing adherence to oral endocrine therapy in early breast cancer patients: a retrospective cohort study in Catalonia, Spain. Br J Cancer 2012; 107: 1249-1256.
4. Geer J, Amoyal N, Nisotel L et al. A systematic review of adherence to oral antineoplastic therapies. Oncologist 2016; 21: 354-376.
5. DiMatteo RM. Variations in patients' adherence to medical recommendations: a quantitative review of 50 years of research.Med Care 2004; 42: 200-209.
6. Knobel H, Alonso J, Casado JL et al. Validation of a simplified medication adherence questionnaire in a large cohort of HIV infected patients: the GEEMA study. Aids 2002; 16: 60-13.
7. Hershman DL, Kushi LH, Shao T et al. Early discontinuation and nonadherence to adjuvant hormonal therapy in a cohort of 8,769 early-stage breast cancer patients. J Clin Oncol 2010; 28: 4120-4128.
8. Herrero MJ, Blanch J, Peri JM et al. A validation study of the hospital anxiety and depression scale (HADS) in a Spanish population. Gen Hosp Psychiatry 2003; 25(4): 277-283.
9. Arraras JL, Suarez J, Arias F et al. Quality of life assessment by applying EORTC questionnaires to rectal cancer patients after surgery and neoadjuvant and adjuvant treatment. Rev Esp Enferm Dig 2013; 105: 255-261.
10. Hosmer DW, Lemeshow S. Applied Logistic Regression. 2nd ed. New York: John Wiley 2000.
11. Gwet KL. Kappa statistic is not satisfactory for assessing the extent of agreement between raters. Stat Methods Inter-Rater Reliab Assess 2002; 1(6): 1-6.
12. Garber MC, Nau D, Erickson SR et al. The concordance of self-report with other measures of medication adherence: a summary of the literature. Med Care 2004; 42: 649-652.
13. Stirret MJ, Dunbar-Jacob J, Crane H et al. Self-reported measures of medication adherence behaviour: recommendations on optimal use. Transl Behav Med 2015; 5: 470-482.
14. Figueiredo Junior AG, Fornoes NM. Study on adherence to capecitabine among patients with colorrectal cancer and metastatic breast cancer. Arq Gastroenterol 2014; 51: 186-191.
15. Simmons S, Ringsdorf S, Braun M et al. Enhancing adherence to capecitabine chemotherapy by means of multidisciplinary pharmaceutical care. Support Care Cancer 2011; 19: 1009-1018.
16. Bhattacharya D, Easthall C, Willoughby KA et al. Capecitabine non adherence: exploration of magnitude, nature and contributing factors. J Oncol Pharm Pract 2012; 18: 333-342.
17. Krolop L, Ko YD, Schwindt PF et al. Adherence management for patients with cancer taking capecitabine: a prospective two arm study. BMJ Open 2013; 3: e003139.
18. Barillet M, Prevost V, Joly VF, Clarisse B. Oral antineoplasic agents: how do we care about adherence? Br J Clin Pharmacol 2015; 80: 1289-1302.