Physiologic effects of high-flow nasal cannula in acute hypoxemic respiratory failure

American Journal of Respiratory and Critical Care Medicine

Volumn 195, Issue 9, 2017, Pages 1207-1215

  Mauri, Tommaso ^a,b   Turrini, Cecilia ^a,c   Eronia, Nilde ^d   Grasselli, Giacomo ^a   Volta, Carlo Alberto ^c   Bellani, Giacomo ^d,e   Pesenti, Antonio ^a,b  

^a FONDAZIONE IRCCS CA GRANDA OSPEDALE MAGGIORE POLICLINICO   (Italy)

^b UNIVERSITY OF MILAN   (Italy)

^c UNIVERSITY OF FERRARA   (Italy)

^d SAN GERARDO HOSPITAL   (Italy)

^e UNIVERSITY OF MILANO BICOCCA   (Italy)

Author keywords

Acute lung injury; Electrical impedance tomography; Esophageal pressure; High flow nasal oxygen

Indexed keywords

ACUTE RESPIRATORY FAILURE; ADULT; AGED; ARTERIAL GAS; ARTICLE; ASSISTED VENTILATION; BREATHING RATE; CARBON DIOXIDE TENSION; CLINICAL ARTICLE; COMPUTER ASSISTED IMPEDANCE TOMOGRAPHY; CONTROLLED STUDY; CROSSOVER PROCEDURE; END EXPIRATORY LUNG VOLUME; ESOPHAGUS PRESSURE; FACE MASK; FEMALE; GAS EXCHANGE; HIGH FLOW NASAL CANNULA; HUMAN; HYPOXEMIA; INSPIRATORY EFFORT; LUNG COMPLIANCE; LUNG HEMODYNAMICS; LUNG MINUTE VOLUME; LUNG VENTILATION DISTRIBUTION; LUNG VOLUME; MALE; MIDDLE AGED; NASAL CANNULA; OXYGEN BREATHING; PH; PRIORITY JOURNAL; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; RESPIRATORY AIRFLOW; RESPIRATORY TRACT PARAMETERS; THERAPY EFFECT; TIDAL VOLUME; WORK OF BREATHING; BLOOD GAS ANALYSIS; CANNULA; HYPOXIA; OXYGEN THERAPY; PATHOPHYSIOLOGY; PROCEDURES; RESPIRATORY INSUFFICIENCY; VERY ELDERLY;

ADULT; AGED; AGED, 80 AND OVER; BLOOD GAS ANALYSIS; CANNULA; CROSS-OVER STUDIES; FEMALE; HUMANS; HYPOXIA; LUNG VOLUME MEASUREMENTS; MALE; MIDDLE AGED; OXYGEN INHALATION THERAPY; PROSPECTIVE STUDIES; RESPIRATORY INSUFFICIENCY; WORK OF BREATHING;

EID: 85018954291     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.201605-0916OC     Document Type: Article

References (39)

1. Papazian L, Corley A, Hess D., Fraser JF, Frat JP, Guitton C, Jaber S., Maggiore SM, Nava S, Rello J, et al Use of high-flow nasal cannula oxygenation in ICU adults: a narrative review. Intensive Care Med 2016; 42:1336-1349.
2. Wilkinson D, Andersen C, O'Donnell CP, De Paoli AG, Manley BJ. High flow nasal cannula for respiratory support in preterm infants. Cochrane Database Syst Rev 2016; 2:CD006405.
3. Nishimura M. High-flow nasal cannula oxygen therapy in adults: physiological benefits, indication, clinical benefits, and adverse effects. Respir Care 2016; 61:529-541.
4. Maggiore SM, Idone FA, Vaschetto R, Festa R., Cataldo A, Antonicelli F, Montini L., De Gaetano A, Navalesi P, Antonelli M. Nasal high-flow versus Venturi mask oxygen therapy after extubation: effects on oxygenation, comfort, and clinical outcome. Am J Respir Crit Care Med 2014; 190:282-288.
5. Frat JP, Thille AW, Mercat A, Girault C., Ragot S, Perbet S, Prat G., Boulain T, Morawiec E, Cottereau A., et al.; FLORALI Study Group; REVA Network. High-flow oxygen through nasal cannula in acute hypoxemic respiratory failure. N Engl J Med 2015; 372: 2185-2196.
6. Stephan F, Barrucand B, Petit P., Rézaiguia-Delclaux S, Médard A, Delannoy B, Cosserant B, Flicoteaux G, Imbert A, Pilorge C, et al.; BiPOP Study Group. High-flow nasal oxygen vs noninvasive positive airway pressure in hypoxemic patients after cardiothoracic surgery: a randomized clinical trial. JAMA 2015; 313:2331-2339.
7. Hernandez G, Vaquero C, Gonzalez P., Subira C, Frutos-Vivar F, Rialp G, Laborda C., Colinas L, Cuena R, Fernandez R. Effect of postextubation high-flow nasal cannula vs conventional oxygen therapy on reintubation in low-risk patients: a randomized clinical trial. JAMA 2016; 315:1354-1361.
8. Spoletini G, Alotaibi M, Blasi F., Hill NS. Heated humidified high-flow nasal oxygen in adults: mechanisms of action and clinical implications. Chest 2015; 148:253-261.
9. Lenglet H, Sztrymf B, Leroy C., Brun P, Dreyfuss D, Ricard JD Humidified high flow nasal oxygen during respiratory failure in the emergency department: feasibility and efficacy. Respir Care 2012; 57: 1873-1878.
10. Bräunlich J., Beyer D, Mai D., Hammerschmidt S, Seyfarth HJ, Wirtz H. Effects of nasal high flow on ventilation in volunteers, COPD and idiopathic pulmonary fibrosis patients. Respiration 2013; 85: 319-325.
11. Pham TM, O'Malley L, Mayfield S, Martin S., Schibler A. The effect of high flow nasal cannula therapy on the work of breathing in infants with bronchiolitis. Pediatr Pulmonol 2015; 50:713-720.
12. Fraser JF, Spooner AJ, Dunster K.R., Anstey CM, Corley A. Nasal high flow oxygen therapy in patients with COPD reduces respiratory rate and tissue carbon dioxide while increasing tidal and end-expiratory lung volumes: a randomised crossover trial. Thorax 2016; 71: 759-761.
13. Babcock MA, Pegelow DF, Harms C.A., Dempsey JA. Effects of respiratory muscle unloading on exercise-induced diaphragm fatigue. J Appl Physiol (1985) 2002; 93:201-206.
14. Bellani G, Guerra L, Musch G., Zanella A, Patroniti N, Mauri T., Messa C, Pesenti A. Lung regional metabolic activity and gas volume changes induced by tidal ventilation in patients with acute lung injury. Am J Respir Crit Care Med 2011; 183:1193-1199.
15. Mauri T, Eronia N, Grasselli G., Tagliabue P, Rona R, Suriano G., Bellani G, Pesenti A. Mechanisms underlying relief of dyspnea by high flow nasal cannula in acute respiratory failure patients. Am J Respir Crit Care Med 2015; 191:A1181.
16. Mojoli F, Chiumello D, Pozzi M., Algieri I, Bianzina S, Luoni S., Volta CA, Braschi A, Brochard L. Esophageal pressure measurements under different conditions of intrathoracic pressure: an in vitro study of second generation balloon catheters. Minerva Anestesiol 2015; 81: 855-864.
17. Mojoli F, Iotti GA, Torriglia F, Pozzi M., Volta CA, Bianzina S, Braschi A, Brochard L. In vivo calibration of esophageal pressure in the mechanically ventilated patient makes measurements reliable. Crit Care 2016; 20:98.
18. Mauri T, Eronia N, Abbruzzese C., Marcolin R, Coppadoro A, Spadaro S., Patroniti N, Bellani G, Pesenti A. Effects of sigh on regional lung strain and ventilation heterogeneity in acute respiratory failure patients undergoing assisted mechanical ventilation. Crit Care Med 2015; 43:1823-1831.
19. Vargas F, Saint-Leger M, Boyer A., Bui NH, Hilbert G. Physiologic effects of high-flow nasal cannula oxygen in critical care subjects. Respir Care 2015; 60:1369-1376.
20. Schwabbauer N, Berg B, Blumenstock G., Haap M, Hetzel J, Riessen R. Nasal high-flow oxygen therapy in patients with hypoxic respiratory failure: effect on functional and subjective respiratory parameters compared to conventional oxygen therapy and non-invasive ventilation (NIV). BMC Anesthesiol 2014; 14:66.
21. Mauri T, Yoshida T, Bellani G., Goligher EC, Carteaux G, Rittayamai N, Mojoli F., Chiumello D, Piquilloud L, Grasso S., et al.; PLeUral pressure working Group (PLUG - Acute Respiratory Failure section of the European Society of Intensive Care Medicine). Esophageal and transpulmonary pressure in the clinical setting: meaning, usefulness and perspectives. Intensive Care Med 2016; 42: 1360-1373.
22. Parke RL, McGuinness SP Pressures delivered by nasal high flow oxygen during all phases of the respiratory cycle. Respir Care 2013; 58:1621-1624.
23. Wexler HR, Lok P. A simple formula for adjusting arterial carbon dioxide tension. Can Anaesth Soc J 1981; 28:370-372.
24. Zhao Z, Pulletz S, Frerichs I., Müller-Lisse U, Möller K. The EIT-based global inhomogeneity index is highly correlated with regional lung opening in patients with acute respiratory distress syndrome. BMC Res Notes 2014; 7:82.
25. Cressoni M, Cadringher P, Chiurazzi C., Amini M, Gallazzi E, Marino A., Brioni M, Carlesso E, Chiumello D., Quintel M, et al. Lung inhomogeneity in patients with acute respiratory distress syndrome. Am J Respir Crit Care Med 2014; 189:149-158.
26. Mertens M, Tabuchi A, Meissner S., Krueger A, Schirrmann K, Kertzscher U., Pries AR, Slutsky AS, Koch E, Kuebler WM Alveolar dynamics in acute lung injury: heterogeneous distension rather than cyclic opening and collapse. Crit Care Med 2009; 37:2604-2611.
27. Bodenstein M, Boehme S, Bierschock S., Vogt A, David M, Markstaller K. Determination of respiratory gas flow by electrical impedance tomography in an animal model of mechanical ventilation. BMCPulm Med 2014; 14:73.
28. Barnard PA, Levine S. Critique on application of diaphragmatic time-tension index to spontaneously breathing humans. J Appl Physiol (1985) 1986; 60:1067-1072.
29. Saslow JG, Aghai ZH, Nakhla T.A., Hart JJ, Lawrysh R, Stahl GE, Pyon KH Work of breathing using high-flow nasal cannula in preterm infants. J Perinatol 2006; 26:476-480.
30. Pesenti A, Rossi N, Calori A., Foti G, Rossi GP. Effects of short-term oxygenation changes on acute lung injury patients undergoing pressure support ventilation. Chest 1993; 103:1185-1189.
31. Nuckton TJ, Alonso JA, Kallet R.H., Daniel BM, Pittet JF, Eisner MD, Matthay MA Pulmonary dead-space fraction as a risk factor for death in the acute respiratory distress syndrome. N Engl J Med 2002; 346:1281-1286.
32. Sztrymf B, Messika J, Bertrand F., Hurel D, Leon R, Dreyfuss D., Ricard JD. Beneficial effects of humidified high flow nasal oxygen in critical care patients: a prospective pilot study. Intensive Care Med 2011; 37: 1780-1786.
33. Yoshida T, Roldan R, Beraldo M.A., Torsani V., Gomes S, De Santis RR, Costa EL, Tucci MR, Lima RG, Kavanagh B.P., et al. Spontaneous effort during mechanical ventilation: maximal injury with less positive end-expiratory pressure. Crit Care Med 2016; 44:e678-e688.
34. Brochard L, Slutsky A, Pesenti A. Mechanical ventilation to minimize progression of lung injury in acute respiratory failure. Am J Respir Crit Care Med 2017; 195:438-442.
35. Hraiech S, Yoshida T, Papazian L. Balancing neuromuscular blockade versus preserved muscle activity. Curr Opin Crit Care 2015; 21:26-33.
36. van der Burg PS, Miedema M, de Jongh FH, Frerichs I, van Kaam AH. Cross-sectional changes in lung volume measured by electrical impedance tomography are representative for the whole lung in ventilated preterm infants. Crit Care Med 2014; 42:1524-1530.
37. Grivans C, Lundin S, Stenqvist O., Lindgren S. Positive end-expiratory pressure-induced changes in end-expiratory lung volume measured by spirometry and electric impedance tomography. Acta Anaesthesiol Scand 2011; 55:1068-1077.
38. Mauri T, Eronia N, Turrini C., Battistini M, Grasselli G, Rona R., Volta CA, Bellani G, Pesenti A. Bedside assessment of the effects of positive end-expiratory pressure on lung inflation and recruitment by the helium dilution technique and electrical impedance tomography. Intensive Care Med 2016; 42:1576-1587.
39. Bellani G, Mauri T, Coppadoro A., Grasselli G, Patroniti N, Spadaro S., Sala V, Foti G, Pesenti A. Estimation of patient's inspiratory effort from the electrical activity of the diaphragm. Crit Care Med 2013; 41:1483-1491.