Variability in antibiotic prescribing for community-acquired pneumonia

Pediatrics

Volumn 139, Issue 4, 2017, Pages

  Handy, Lori K ^a,b   Bryan, Matthew ^c,e,f   Gerber, Jeffrey S ^c,d,e,f   Zaoutis, Theoklis ^c,d,e,f,g   Feemster, Kristen A ^c,d,g  

^a NEMOURS ALFRED I DUPONT HOSPITAL FOR CHILDREN   (United States)

^b THOMAS JEFFERSON UNIVERSITY   (United States)

^c Center for Pediatric Clinical Effectiveness   (United States)

^d CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^e Department of Biostatistics and Epidemiology ^*  (United States)

^f Center for Clinical Epidemiology and Biostatistics   (United States)

^g UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMOXICILLIN; AMOXICILLIN PLUS CLAVULANIC ACID; ANTIBIOTIC AGENT; CEPHALOSPORIN; MACROLIDE; QUINOLINE DERIVED ANTIINFECTIVE AGENT; ANTIINFECTIVE AGENT;

ADOLESCENT; ADULT; AGE; ANTIBIOTIC THERAPY; ARTICLE; BACTERIAL PNEUMONIA; CHILD; CHILD HEALTH INSURANCE; COHORT ANALYSIS; COMMUNITY ACQUIRED PNEUMONIA; CONTROLLED STUDY; DRUG CHOICE; FEMALE; HUMAN; INFANT; MAJOR CLINICAL STUDY; MALE; MEDICAL PRACTICE; OUTPATIENT DEPARTMENT; PREDICTION; PRESCRIPTION; PRIMARY MEDICAL CARE; PRIVATE HEALTH INSURANCE; RETROSPECTIVE STUDY; URBAN HEALTH; AMBULATORY CARE; CLINICAL PRACTICE; COMMUNITY-ACQUIRED INFECTIONS; PNEUMONIA; PRESCHOOL CHILD; STATISTICS AND NUMERICAL DATA;

ADOLESCENT; AMBULATORY CARE; ANTI-BACTERIAL AGENTS; CHILD; CHILD, PRESCHOOL; COHORT STUDIES; COMMUNITY-ACQUIRED INFECTIONS; FEMALE; HUMANS; INFANT; MALE; PNEUMONIA; PRACTICE PATTERNS, PHYSICIANS'; RETROSPECTIVE STUDIES;

EID: 85018947098     PISSN: 00314005     EISSN: 10984275     Source Type: Journal    
DOI: 10.1542/peds.2016-2331     Document Type: Article

References (29)

1. Kronman MP, Hersh AL, Feng R, Huang YS, Lee GE, Shah SS. Ambulatory visit rates and antibiotic prescribing for children with pneumonia, 1994-2007. Pediatrics. 2011;127(3):411-418
2. Bradley JS, Byington CL, Shah SS, et al; Pediatric Infectious Diseases Society and the Infectious Diseases Society of America. Executive summary: the management of community-acquired pneumonia in infants and children older than 3 months of age: clinical practice guidelines by the Pediatric Infectious Diseases Society and the Infectious Diseases Society of America. Clin Infect Dis. 2011;53(7):617-630
3. Gerber JS, Prasad PA, Fiks AG, et al. Effect of an outpatient antimicrobial stewardship intervention on broad-spectrum antibiotic prescribing by primary care pediatricians: a randomized trial. JAMA. 2013;309(22):2345-2352
4. Brogan TV, Hall M, Williams DJ, et al. Variability in processes of care and outcomes among children hospitalized with community-acquired pneumonia. Pediatr Infect Dis J. 2012;31(10):1036-1041
5. Queen MA, Myers AL, Hall M, et al.comparative effectiveness of empiric antibiotics for community-acquired pneumonia. Pediatrics. 2014;133(1). Available at: www.pediatrics.org/cgi/content/full/133/1/e23
6. Hersh AL, Shapiro DJ, Pavia AT, Shah SS. Antibiotic prescribing in ambulatory pediatrics in the United States. Pediatrics. 2011;128(6): 1053-1061
7. Lee GM, Kleinman K, Pelton SI, et al. Impact of 13-valent pneumococcal conjugate vaccination on Streptococcus pneumoniae carriage in young children in Massachusetts. J Pediatric Infect Dis Soc. 2014;3(1):23-32
8. Morozumi M, Chiba N, Okada T, et al. Antibiotic susceptibility in relation to genotype of Streptococcus pneumoniae, Haemophilus infl uenzae, and Mycoplasma pneumoniae responsible for community-acquired pneumonia in children. J Infect Chemother. 2013;19(3):432-440
9. Zhanel GG, Wolter KD, Calciu C, et al. Clinical cure rates in subjects treated with azithromycin for communityacquired respiratory tract infections caused by azithromycin-susceptible or azithromycin-resistant Streptococcus pneumoniae: analysis of Phase 3 clinical trial data. J Antimicrob Chemother. 2014;69(10):2835-2840
10. Khabbaz RF, Moseley RR, Steiner RJ, Levitt AM, Bell BP. Challenges of infectious diseases in the USA. Lancet. 2014;384(9937):53-63
11. Kuster SP, Rudnick W, Shigayeva A, et al; Toronto Invasive Bacterial Diseases Network. Previous antibiotic exposure and antimicrobial resistance in invasive pneumococcal disease: results from prospective surveillance. Clin Infect Dis. 2014;59(7):944-952
12. Wang K, Gill P, Perera R, Thomson A, Mant D, Harnden A. Clinical symptoms and signs for the diagnosis of Mycoplasma pneumoniae in children and adolescents with communityacquired pneumonia. Cochrane Database Syst Rev. 2012;(10):CD009175
13. Chang HY, Chang LY, Shao PL, et al.comparison of real-time polymerase chain reaction and serological tests for the confirmation of Mycoplasma pneumoniae infection in children with clinical diagnosis of atypical pneumonia. J Microbiol Immunol Infect. 2014;47(2):137-144
14. Gerber JS, Prasad PA, Localio AR, et al. Racial differences in antibiotic prescribing by primary care pediatricians. Pediatrics. 2013;131(4):677-684
15. Hicks LA, Taylor TH Jr, Hunkler RJ. U.S. outpatient antibiotic prescribing, 2010. N Engl J Med. 2013;368(15):1461-1462
16. Sarpong EM, Miller GE. Narrow-and broad-spectrum antibiotic use among U.S. children. Health Serv Res. 2015;50(3):830-846
17. Fleming-Dutra KE, Shapiro DJ, Hicks LA, Gerber JS, Hersh AL. Race, otitis media, and antibiotic selection. Pediatrics. 2014;134(6):1059-1066
18. Yaeger JP, Temte JL, Hanrahan LP, Martinez-Donate P. Roles of clinician, patient, and community characteristics in the management of pediatric upper respiratory tract infections. Ann Fam Med. 2015;13(6):529-536
19. Cabana MD, Rand CS, Powe NR, et al. Why don't physicians follow clinical practice guidelines? A framework for improvement. JAMA. 1999;282(15):1458-1465
20. Feudtner C, Christakis DA, Connell FA. Pediatric deaths attributable to complex chronic conditions: a population-based study of Washington State, 1980-1997. Pediatrics. 2000;106(1 pt 2):205-209
21. Williams DJ, Shah SS, Myers A, et al. Identifying pediatric communityacquired pneumonia hospitalizations: Accuracy of administrative billing codes. JAMA Pediatr. 2013;167(9):851-858
22. Guevara RE, Butler JC, Marston BJ, Plouffe JF, File TM Jr, Breiman RF. Accuracy of ICD-9-CM codes in detecting community-acquired pneumococcal pneumonia for incidence and vaccine efficacy studies. Am J Epidemiol. 1999;149(3):282-289
23. World Health Organization. Technical Bases for the WHO Recommendations on the Management of Pneumonia in Children at First-Level Health Facilities. Geneva, Switzerland: World Health Organization; 1991.
24. Cardoso MR, Nascimento-Carvalho CM, Ferrero F, Alves FM, Cousens SN. Adding fever to WHO criteria for diagnosing pneumonia enhances the ability to identify pneumonia cases among wheezing children. Arch Dis Child. 2011;96(1):58-61
25. Angoulvant F, Levy C, Grimprel E, et al. Early impact of 13-valent pneumococcal conjugate vaccine on community-acquired pneumonia in children. Clin Infect Dis. 2014;58(7):918-924
26. Lee GE, Lorch SA, Sheffl er-Collins S, Kronman MP, Shah SS. National hospitalization trends for pediatric pneumonia and associated complications. Pediatrics. 2010;126(2):204-213
27. Williams DJ, Shah SS.communityacquired pneumonia in the conjugate vaccine era. J Pediatric Infect Dis Soc. 2012;1(4):314-328
28. Jain S, Williams DJ, Arnold SR, et al; CDC EPIC Study Team.communityacquired pneumonia requiring hospitalization among U.S. children. N Engl J Med. 2015;372(9):835-845
29. Szymczak JE, Feemster KA, Zaoutis TE, Gerber JS. Pediatrician perceptions of an outpatient antimicrobial stewardship intervention. Infect Control Hosp Epidemiol. 2014;35(suppl 3):S69-S78