Troponin Release Following Brief Myocardial Ischemia: Apoptosis Versus Necrosis

JACC: Basic to Translational Science

Volumn 2, Issue 2, 2017, Pages 118-121

  Amgalan, Dulguun ^a   Pekson, Ryan ^a   Kitsis, Richard N ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

apoptosis; cell death; ischemia; necrosis; troponin

Indexed keywords

EID: 85018820064     PISSN: 2452302X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jacbts.2017.03.008     Document Type: Editorial

References (5)

1. 1 Giannitsis, E., Katus, H.A., Cardiac troponin level elevations not related to acute coronary syndromes. Nat Rev Cardiol 10 (2013), 623–634.
2. 2 Weil, B.R., Young, R.F., Shen, X., et al. Brief myocardial ischemia produces cardiac troponin I release and focal myocyte apoptosis in the absence of pathological infarction in swine. J Am Coll Cardiol Basic Trans Science 2 (2017), 105–114.
3. 3 White, H.D., Pathobiology of troponin elevations: do elevations occur with myocardial ischemia as well as necrosis?. J Am Coll Cardiol 57 (2011), 2406–2408.
4. 4 Jennings, R.B., Sommers, H.M., Herdson, P.B., Kaltenbach, J.P., Ischemic injury of myocardium. Ann NY Acad Sci 156 (1969), 61–78.
5. 5 Konstantinidis, K., Whelan, R.S., Kitsis, R.N., Mechanisms of cell death in heart disease. Arterioscler Thromb Vasc Biol 32 (2012), 1552–1562.