Ebola virus disease in children during the 2014–2015 epidemic in Guinea: a nationwide cohort study

European Journal of Pediatrics

Volumn 176, Issue 6, 2017, Pages 791-796

  Chérif, Mahamoud Sama ^a,b   Koonrungsesomboon, Nut ^b,c   Kassé, Diénaba ^a   Cissé, Sékou Ditinn ^a   Diallo, Saliou Bella ^a   Chérif, Fatoumata ^d   Camara, Facély ^a   Koné, Alpha ^a   Avenido, Eleonor Fundan ^b   Diakité, Mandiou ^a   Diallo, Mamadou Pathé ^a   Le Gall, Edouard ^a,e   Cissé, Mohamed ^a   Karbwang, Juntra ^b   Hirayama, Kenji ^b  

^a Université Gamal Abdel Nasser de Conakry   (Guinea)

^b NAGASAKI UNIVERSITY   (Japan)

^c Faculty of Medicine Chiang Mai University   (Thailand)

^d Ministry of Health and Public Hygiene   (Guinea)

^e Pole Regional de Cancerologie Bretagne   (France)

Author keywords

Child; Ebola virus disease; Ebola virus infection; Epidemics; Guinea; Pediatrics

Indexed keywords

ABDOMINAL PAIN; ADOLESCENT; ADULT; ANOREXIA; ARTHRALGIA; ARTICLE; BLEEDING; CASE FATALITY RATE; CHILD; CHILDHOOD MORTALITY; CLINICAL FEATURE; COHORT ANALYSIS; CONJUNCTIVITIS; COUGHING; DIARRHEA; DYSPNEA; EBOLA HEMORRHAGIC FEVER; EPIDEMIC; FATIGUE; FEMALE; FEVER; GASTROINTESTINAL SYMPTOM; GUINEA; HEADACHE; HICCUP; HOSPITAL ADMISSION; HUMAN; INFANT; INFECTION RISK; MAJOR CLINICAL STUDY; MALE; MARBURG HEMORRHAGIC FEVER; MYALGIA; NEWBORN; OBSERVATIONAL STUDY; PRIORITY JOURNAL; RETROSPECTIVE STUDY; SORE THROAT; SURVIVAL RATE; THORAX PAIN; VOMITING; AGE; KAPLAN MEIER METHOD; PRESCHOOL CHILD; RISK FACTOR; YOUNG ADULT;

ADOLESCENT; AGE FACTORS; CHILD; CHILD, PRESCHOOL; EPIDEMICS; FEMALE; GUINEA; HEMORRHAGIC FEVER, EBOLA; HUMANS; INFANT; INFANT, NEWBORN; KAPLAN-MEIER ESTIMATE; MALE; RETROSPECTIVE STUDIES; RISK FACTORS; YOUNG ADULT;

EID: 85018717350     PISSN: 03406199     EISSN: 14321076     Source Type: Journal    
DOI: 10.1007/s00431-017-2914-z     Document Type: Article

References (21)

1. Baize S, Pannetier D, Oestereich L, Rieger T, Koivogui L, Magassouba N, Soropogui B et al (2014) Emergence of Zaire Ebola virus disease in Guinea. N Engl J Med 371:1418–1425. doi:10.1056/NEJMoa1404505
2. Bower H, Smout E, Bangura MS, Kamara O, Turay C, Johnson S, Oza S, Checchi F, Glynn JR (2016) Deaths, late deaths, and role of infecting dose in Ebola virus disease in Sierra Leone: retrospective cohort study. BMJ 353:i2403. doi:10.1136/bmj.i2403
3. Eriksson CO, Uyeki TM, Christian MD, King MA, Braner DA, Kanter RK, Kissoon N (2015) Care of the child with Ebola virus disease. Pediatr Crit Care Med 16:97–103. doi:10.1097/PCC.0000000000000358
4. Faye O, Andronico A, Salje H, Boëlle PY, Magassouba N, Bah EI, Koivogui L, Diallo B, Diallo AA, Keita S, Konde MK, Fowler R, Fall G, Cauchemez S, Sall AA (2015) Use of viremia to evaluate the baseline case fatality ratio of Ebola virus disease and inform treatment studies: a retrospective cohort study. PLoS Med 12:e1001908. doi:10.1371/journal.pmed.1001908
5. Fitzgerald F, Naveed A, Wing K, Gbessay M, Ross JC, Checchi F, Youkee D, Jalloh MB, Baion D, Mustapha A, Jah H, Lako S, Oza S, Boufkhed S, Feury R, Bielicki JA, Gibb DM, Klein N, Sahr F, Yeung S (2016) Ebola virus disease in children, Sierra Leone, 2014-2015. Emerg Infect Dis 22:1769–1777. doi:10.3201/eid2210.160579
6. Kourtis AP, Appelgren K, Chevalier MS, McElroy A (2015) Ebola virus disease: focus on children. Pediatr Infect Dis J 34:893–897. doi: 10.1097/INF.0000000000000707
7. Leligdowicz A, Fischer WA, Uyeki TM, Fletcher TE, Adhikari NK, Portella G, Lamontagne F et al (2016) Ebola virus disease and critical illness. Crit Care 20:217. doi:10.1186/s13054-016-1325-2
8. McElroy AK, Erickson BR, Flietstra TD, Rollin PE, Nichol ST, Towner JS, Spiropoulou CF (2014) Biomarker correlates of survival in pediatric patients with Ebola virus disease. Emerg Infect Dis 20:1683–1690. doi:10.3201/eid2010.140430
9. Peacock G, Uyeki TM, Rasmussen SA (2014) Ebola virus disease and children: what pediatric health care professionals need to know. JAMA Pediatr 168:1087–1088. doi:10.1001/jamapediatrics.2014.2835
10. Shah T (2015) Ebola in children: a personal perspective. J Virus Erad 1:206–207
11. Shah T, Greig J, van der Plas LM, Achar J, Caleo G, Squire JS, Turay AS, Joshy G, D’Este C, Banks E, Vogt F, Lokuge K (2016) Inpatient signs and symptoms and factors associated with death in children aged 5 years and younger admitted to two Ebola management centres in Sierra Leone, 2014: a retrospective cohort study. Lancet Glob Health 4:e495–50122. doi: 10.1016/S2214-109X(16)30097-3
12. Trad MA, Naughton W, Yeung A, Mazlin L, O’sullivan M, Gilroy N, Fisher DA, Stuart RL (2017) Ebola virus disease: an update on current prevention and management strategies. J Clin Virol 86:5–13. doi:10.1016/j.jcv.2016.11.005
13. WHO Ebola Response Team (2014) Ebola virus disease in West Africa—the first 9 months of the epidemic and forward projections. N Engl J Med 371:1481–1495. doi:10.1056/NEJMoa1411100
14. WHO Ebola Response Team (2015a) West African Ebola epidemic after one year—slowing but not yet under control. N Engl J Med 372:584–587. doi:10.1056/NEJMc1414992
15. WHO Ebola Response Team (2015b) Ebola virus disease among children in West Africa. N Engl J Med 372:1274–1277. doi:10.1056/NEJMc1415318
16. Wong JY, Zhang W, Kargbo D, Haque U, Hu W, Wu P, Kamara A, Chen Y, Kargbo B, Glass GE, Yang R, Cowling BJ, Liu C (2016) Assessment of the severity of Ebola virus disease in Sierra Leone in 2014-2015. Epidemiol Infect 144:1473–1481. doi:10.1017/S0950268815003003
17. World Health Organization (2014) Case definition recommendations for Ebola or Marburg virus diseases. http://www.who.int/csr/resources/publications/ebola/ebola-case-definition-contact-en.pdf. Accessed 5 May 2016
18. World Health Organization (2016a) Situation report: Ebola virus disease. http://apps.who.int/iris/bitstream/10665/208883/1/ebolasitrep_10Jun2016_eng.pdf. Accessed 26 December 2016
19. World Health Organization (2016b) Ebola situation report. http://apps.who.int/ebola/current-situation/ebola-situation-report-30-march-2016. Accessed 26 December 2016
20. World Health Organization (2016c) End of Ebola transmission in Guinea. http://www.who.int/mediacentre/news/releases/2016/ebola-guinea/en/. Accessed 26 December 2016
21. World Health Organization (2016d) End of the most recent Ebola virus disease outbreak in Liberia. http://www.who.int/mediacentre/news/releases/2016/ebola-liberia/en/. Accessed 26 December 2016