-
1
-
-
77950988234
-
Infliximab, azathioprine, or combination therapy for Crohn's disease
-
Colombel JF, Sandborn WJ, Reinisch W, et al. Infliximab, azathioprine, or combination therapy for Crohn's disease. N Engl J Med. 2010;362:1383-1395.
-
(2010)
N Engl J Med
, vol.362
, pp. 1383-1395
-
-
Colombel, J.F.1
Sandborn, W.J.2
Reinisch, W.3
-
2
-
-
84892737455
-
Combination therapy with infliximab and azathioprine is superior to monotherapy with either agent in ulcerative colitis
-
Panaccione R, Ghosh S, Middleton S, et al. Combination therapy with infliximab and azathioprine is superior to monotherapy with either agent in ulcerative colitis. Gastroenterology. 2014;146:392-400.
-
(2014)
Gastroenterology
, vol.146
, pp. 392-400
-
-
Panaccione, R.1
Ghosh, S.2
Middleton, S.3
-
3
-
-
84988710033
-
Crohn's disease activity and concomitant immunosuppressants affect the risk of serious and opportunistic infections in patients treated with adalimumab
-
Osterman MT, Sandborn WJ, Colombel JF, et al. Crohn's disease activity and concomitant immunosuppressants affect the risk of serious and opportunistic infections in patients treated with adalimumab. Am J Gastroenterol. 2016;111:1806-1815.
-
(2016)
Am J Gastroenterol
, vol.111
, pp. 1806-1815
-
-
Osterman, M.T.1
Sandborn, W.J.2
Colombel, J.F.3
-
4
-
-
84931371979
-
Effectiveness and safety of immunomodulators with anti-tumor necrosis factor therapy in Crohn's disease
-
Osterman MT, Haynes K, Delzell E, et al. Effectiveness and safety of immunomodulators with anti-tumor necrosis factor therapy in Crohn's disease. Clin Gastroenterol Hepatol. 2015;13:1293-1301.
-
(2015)
Clin Gastroenterol Hepatol
, vol.13
, pp. 1293-1301
-
-
Osterman, M.T.1
Haynes, K.2
Delzell, E.3
-
5
-
-
41349088375
-
Risk factors for opportunistic infections in patients with inflammatory bowel disease
-
Toruner M, Loftus EV Jr, Harmsen WS, et al. Risk factors for opportunistic infections in patients with inflammatory bowel disease. Gastroenterology. 2008;134:929-936.
-
(2008)
Gastroenterology
, vol.134
, pp. 929-936
-
-
Toruner, M.1
Loftus, E.V.2
Harmsen, W.S.3
-
6
-
-
70449100743
-
Lymphoproliferative disorders in patients receiving thiopurines for inflammatory bowel disease: a prospective observational cohort study
-
Beaugerie L, Brousse N, Bouvier AM, et al. Lymphoproliferative disorders in patients receiving thiopurines for inflammatory bowel disease: a prospective observational cohort study. Lancet. 2009;374:1617-1625.
-
(2009)
Lancet
, vol.374
, pp. 1617-1625
-
-
Beaugerie, L.1
Brousse, N.2
Bouvier, A.M.3
-
7
-
-
84872024555
-
T-cell non-Hodgkin's lymphomas reported to the FDA AERS with tumor necrosis factor-alpha (TNF-alpha) inhibitors: results of the REFURBISH study
-
Deepak P, Sifuentes H, Sherid M, Stobaugh D, Sadozai Y, Ehrenpreis ED. T-cell non-Hodgkin's lymphomas reported to the FDA AERS with tumor necrosis factor-alpha (TNF-alpha) inhibitors: results of the REFURBISH study. Am J Gastroenterol. 2013;108:99-105.
-
(2013)
Am J Gastroenterol
, vol.108
, pp. 99-105
-
-
Deepak, P.1
Sifuentes, H.2
Sherid, M.3
Stobaugh, D.4
Sadozai, Y.5
Ehrenpreis, E.D.6
-
8
-
-
84925546734
-
Systematic review: monotherapy with antitumour necrosis factor alpha agents versus combination therapy with an immunosuppressive for IBD
-
Dulai PS, Siegel CA, Colombel JF, Sandborn WJ, Peyrin-Biroulet L. Systematic review: monotherapy with antitumour necrosis factor alpha agents versus combination therapy with an immunosuppressive for IBD. Gut. 2014;63:1843-1853.
-
(2014)
Gut
, vol.63
, pp. 1843-1853
-
-
Dulai, P.S.1
Siegel, C.A.2
Colombel, J.F.3
Sandborn, W.J.4
Peyrin-Biroulet, L.5
-
9
-
-
84906790018
-
Risks of serious infection or lymphoma with anti-tumor necrosis factor therapy for pediatric inflammatory bowel disease: a systematic review
-
Dulai PS, Thompson KD, Blunt HB, Dubinsky MC, Siegel CA. Risks of serious infection or lymphoma with anti-tumor necrosis factor therapy for pediatric inflammatory bowel disease: a systematic review. Clin Gastroenterol Hepatol. 2014;12:1443-1451.
-
(2014)
Clin Gastroenterol Hepatol
, vol.12
, pp. 1443-1451
-
-
Dulai, P.S.1
Thompson, K.D.2
Blunt, H.B.3
Dubinsky, M.C.4
Siegel, C.A.5
-
10
-
-
77957836758
-
Hepatosplenic T-cell lymphoma in inflammatory bowel disease: a possible thiopurine-induced chromosomal abnormality
-
Kotlyar DS, Blonski W, Diamond RH, Wasik M, Lichtenstein GR. Hepatosplenic T-cell lymphoma in inflammatory bowel disease: a possible thiopurine-induced chromosomal abnormality. Am J Gastroenterol. 2010;105:2299-2301.
-
(2010)
Am J Gastroenterol
, vol.105
, pp. 2299-2301
-
-
Kotlyar, D.S.1
Blonski, W.2
Diamond, R.H.3
Wasik, M.4
Lichtenstein, G.R.5
-
11
-
-
84927722749
-
Risk of lymphoma in patients with inflammatory bowel disease treated with azathioprine and 6-mercaptopurine: a meta-analysis
-
Kotlyar DS, Lewis JD, Beaugerie L, et al. Risk of lymphoma in patients with inflammatory bowel disease treated with azathioprine and 6-mercaptopurine: a meta-analysis. Clin Gastroenterol Hepatol. 2015;13:847-858.
-
(2015)
Clin Gastroenterol Hepatol
, vol.13
, pp. 847-858
-
-
Kotlyar, D.S.1
Lewis, J.D.2
Beaugerie, L.3
-
12
-
-
78650239266
-
A systematic review of factors that contribute to hepatosplenic T-cell lymphoma in patients with inflammatory bowel disease
-
Kotlyar DS, Osterman MT, Diamond RH, et al. A systematic review of factors that contribute to hepatosplenic T-cell lymphoma in patients with inflammatory bowel disease. Clin Gastroenterol Hepatol. 2011;9:36-41.
-
(2011)
Clin Gastroenterol Hepatol
, vol.9
, pp. 36-41
-
-
Kotlyar, D.S.1
Osterman, M.T.2
Diamond, R.H.3
-
13
-
-
80955142690
-
Hepatosplenic T-cell lymphoma in patients receiving TNF-alpha inhibitor therapy: expanding the groups at risk
-
Parakkal D, Sifuentes H, Semer R, Ehrenpreis ED. Hepatosplenic T-cell lymphoma in patients receiving TNF-alpha inhibitor therapy: expanding the groups at risk. Eur J Gastroenterol Hepatol. 2011;23:1150-1156.
-
(2011)
Eur J Gastroenterol Hepatol
, vol.23
, pp. 1150-1156
-
-
Parakkal, D.1
Sifuentes, H.2
Semer, R.3
Ehrenpreis, E.D.4
-
14
-
-
67949112671
-
Risk of lymphoma associated with combination anti-tumor necrosis factor and immunomodulator therapy for the treatment of Crohn's disease: a meta-analysis
-
Siegel CA, Marden SM, Persing SM, Larson RJ, Sands BE. Risk of lymphoma associated with combination anti-tumor necrosis factor and immunomodulator therapy for the treatment of Crohn's disease: a meta-analysis. Clin Gastroenterol Hepatol. 2009;7:874-881.
-
(2009)
Clin Gastroenterol Hepatol
, vol.7
, pp. 874-881
-
-
Siegel, C.A.1
Marden, S.M.2
Persing, S.M.3
Larson, R.J.4
Sands, B.E.5
-
15
-
-
84864225717
-
Risk of melanoma and nonmelanoma skin cancer among patients with inflammatory bowel disease
-
Long MD, Martin CF, Pipkin CA, Herfarth HH, Sandler RS, Kappelman MD. Risk of melanoma and nonmelanoma skin cancer among patients with inflammatory bowel disease. Gastroenterology. 2012;143:390-399.
-
(2012)
Gastroenterology
, vol.143
, pp. 390-399
-
-
Long, M.D.1
Martin, C.F.2
Pipkin, C.A.3
Herfarth, H.H.4
Sandler, R.S.5
Kappelman, M.D.6
-
16
-
-
84906859283
-
Melanoma and non-melanoma skin cancer in inflammatory bowel disease patients following tumor necrosis factor-alpha inhibitor monotherapy and in combination with thiopurines: analysis of the Food and Drug Administration Adverse Event Reporting System
-
McKenna MR, Stobaugh DJ, Deepak P. Melanoma and non-melanoma skin cancer in inflammatory bowel disease patients following tumor necrosis factor-alpha inhibitor monotherapy and in combination with thiopurines: analysis of the Food and Drug Administration Adverse Event Reporting System. J Gastrointestin Liver Dis. 2014;23:267-271.
-
(2014)
J Gastrointestin Liver Dis
, vol.23
, pp. 267-271
-
-
McKenna, M.R.1
Stobaugh, D.J.2
Deepak, P.3
-
17
-
-
77953801701
-
Review article: malignancy on thiopurine treatment with special reference to inflammatory bowel disease
-
Smith MA, Irving PM, Marinaki AM, Sanderson JD. Review article: malignancy on thiopurine treatment with special reference to inflammatory bowel disease. Aliment Pharmacol Ther. 2010;32:119-130.
-
(2010)
Aliment Pharmacol Ther
, vol.32
, pp. 119-130
-
-
Smith, M.A.1
Irving, P.M.2
Marinaki, A.M.3
Sanderson, J.D.4
-
18
-
-
44649090092
-
Withdrawal of immunosuppression in Crohn's disease treated with scheduled infliximab maintenance: a randomized trial
-
Van Assche G, Magdelaine-Beuzelin C, D'Haens G, et al. Withdrawal of immunosuppression in Crohn's disease treated with scheduled infliximab maintenance: a randomized trial. Gastroenterology. 2008;134:1861-1868.
-
(2008)
Gastroenterology
, vol.134
, pp. 1861-1868
-
-
Van Assche, G.1
Magdelaine-Beuzelin, C.2
D'Haens, G.3
-
19
-
-
77951977369
-
Predictors of infliximab failure after azathioprine withdrawal in Crohn's disease treated with combination therapy
-
Oussalah A, Chevaux JB, Fay R, Sandborn WJ, Bigard MA, Peyrin-Biroulet L. Predictors of infliximab failure after azathioprine withdrawal in Crohn's disease treated with combination therapy. Am J Gastroenterol. 2010;105:1142-1149.
-
(2010)
Am J Gastroenterol
, vol.105
, pp. 1142-1149
-
-
Oussalah, A.1
Chevaux, J.B.2
Fay, R.3
Sandborn, W.J.4
Bigard, M.A.5
Peyrin-Biroulet, L.6
-
20
-
-
84928628450
-
Concentrations of 6-thioguanine nucleotide correlate with trough levels of infliximab in patients with inflammatory bowel disease on combination therapy
-
Yarur AJ, Kubiliun MJ, Czul F, et al. Concentrations of 6-thioguanine nucleotide correlate with trough levels of infliximab in patients with inflammatory bowel disease on combination therapy. Clin Gastroenterol Hepatol. 2015;13:1118-1124.
-
(2015)
Clin Gastroenterol Hepatol
, vol.13
, pp. 1118-1124
-
-
Yarur, A.J.1
Kubiliun, M.J.2
Czul, F.3
-
21
-
-
62049083383
-
Loss of response and requirement of infliximab dose intensification in Crohn's disease: a review
-
Gisbert JP, Panes J. Loss of response and requirement of infliximab dose intensification in Crohn's disease: a review. Am J Gastroenterol. 2009;104:760-767.
-
(2009)
Am J Gastroenterol
, vol.104
, pp. 760-767
-
-
Gisbert, J.P.1
Panes, J.2
-
22
-
-
84925339415
-
Withdrawal of immunomodulators after co-treatment does not reduce trough level of infliximab in patients with Crohn's disease
-
Drobne D, Bossuyt P, Breynaert C, et al. Withdrawal of immunomodulators after co-treatment does not reduce trough level of infliximab in patients with Crohn's disease. Clin Gastroenterol Hepatol. 2015;13:514-521.
-
(2015)
Clin Gastroenterol Hepatol
, vol.13
, pp. 514-521
-
-
Drobne, D.1
Bossuyt, P.2
Breynaert, C.3
-
23
-
-
0037434552
-
Influence of immunogenicity on the long-term efficacy of infliximab in Crohn's disease
-
Baert F, Noman M, Vermeire S, et al. Influence of immunogenicity on the long-term efficacy of infliximab in Crohn's disease. N Engl J Med. 2003;348:601-608.
-
(2003)
N Engl J Med
, vol.348
, pp. 601-608
-
-
Baert, F.1
Noman, M.2
Vermeire, S.3
-
24
-
-
33749432435
-
Association of trough serum infliximab to clinical outcome after scheduled maintenance treatment for Crohn's disease
-
Maser EA, Villela R, Silverberg MS, Greenberg GR. Association of trough serum infliximab to clinical outcome after scheduled maintenance treatment for Crohn's disease. Clin Gastroenterol Hepatol. 2006;4:1248-1254.
-
(2006)
Clin Gastroenterol Hepatol
, vol.4
, pp. 1248-1254
-
-
Maser, E.A.1
Villela, R.2
Silverberg, M.S.3
Greenberg, G.R.4
-
25
-
-
84855197296
-
Early serial trough and antidrug antibody level measurements predict clinical outcome of infliximab and adalimumab treatment
-
Vande Casteele N, Ballet V, Van Assche G, Rutgeerts P, Vermeire S, Gils A. Early serial trough and antidrug antibody level measurements predict clinical outcome of infliximab and adalimumab treatment. Gut 2012;61:321.
-
(2012)
Gut
, vol.61
, pp. 321
-
-
Vande Casteele, N.1
Ballet, V.2
Van Assche, G.3
Rutgeerts, P.4
Vermeire, S.5
Gils, A.6
-
26
-
-
84941330342
-
The relationship between infliximab concentrations, antibodies to infliximab and disease activity in Crohn's disease
-
Vande Casteele N, Khanna R, Levesque BG, et al. The relationship between infliximab concentrations, antibodies to infliximab and disease activity in Crohn's disease. Gut 2015;64:1539-1545.
-
(2015)
Gut
, vol.64
, pp. 1539-1545
-
-
Vande Casteele, N.1
Khanna, R.2
Levesque, B.G.3
-
27
-
-
84938555154
-
Population pharmacokinetics of infliximab in patients with inflammatory bowel disease: potential implications for dosing in clinical practice
-
Buurman DJ, Maurer JM, Keizer RJ, Kosterink JG, Dijkstra G. Population pharmacokinetics of infliximab in patients with inflammatory bowel disease: potential implications for dosing in clinical practice. Aliment Pharmacol Ther. 2015;42:529-539.
-
(2015)
Aliment Pharmacol Ther
, vol.42
, pp. 529-539
-
-
Buurman, D.J.1
Maurer, J.M.2
Keizer, R.J.3
Kosterink, J.G.4
Dijkstra, G.5
-
28
-
-
85013449857
-
Higher infliximab trough levels are associated with perianal fistula healing in patients with Crohn's disease
-
Yarur AJ, Kanagala V, Stein DJ, et al. Higher infliximab trough levels are associated with perianal fistula healing in patients with Crohn's disease. Aliment Pharmacol Ther. 2017;45:933-940.
-
(2017)
Aliment Pharmacol Ther
, vol.45
, pp. 933-940
-
-
Yarur, A.J.1
Kanagala, V.2
Stein, D.J.3
-
29
-
-
84909950686
-
Risk of melanoma and non-melanoma skin cancer in ulcerative colitis patients treated with thiopurines: a nationwide retrospective cohort
-
Abbas AM, Almukhtar RM, Loftus EV Jr, Lichtenstein GR, Khan N. Risk of melanoma and non-melanoma skin cancer in ulcerative colitis patients treated with thiopurines: a nationwide retrospective cohort. Am J Gastroenterol. 2014;109:1781-1793.
-
(2014)
Am J Gastroenterol
, vol.109
, pp. 1781-1793
-
-
Abbas, A.M.1
Almukhtar, R.M.2
Loftus, E.V.3
Lichtenstein, G.R.4
Khan, N.5
-
30
-
-
0023119219
-
Thiopurine pharmacogenetics in leukemia: correlation of erythrocyte thiopurine methyltransferase activity and 6-thioguanine nucleotide concentrations
-
Lennard L, Van Loon JA, Lilleyman JS, et al. Thiopurine pharmacogenetics in leukemia: correlation of erythrocyte thiopurine methyltransferase activity and 6-thioguanine nucleotide concentrations. Clin Pharmacol Ther. 1987;41:18-25.
-
(1987)
Clin Pharmacol Ther
, vol.41
, pp. 18-25
-
-
Lennard, L.1
Van Loon, J.A.2
Lilleyman, J.S.3
-
31
-
-
67650355472
-
Methotrexate/6-mercaptopurine maintenance therapy influences the risk of a second malignant neoplasm after childhood acute lymphoblastic leukemia: results from the NOPHO ALL-92 study
-
Schmiegelow K, Al-Modhwahi I, Andersen MK, et al. Methotrexate/6-mercaptopurine maintenance therapy influences the risk of a second malignant neoplasm after childhood acute lymphoblastic leukemia: results from the NOPHO ALL-92 study. Blood. 2009;113:6077-6084.
-
(2009)
Blood
, vol.113
, pp. 6077-6084
-
-
Schmiegelow, K.1
Al-Modhwahi, I.2
Andersen, M.K.3
-
32
-
-
84982985663
-
Iatrogenic immunosuppression and risk of non-Hodgkin lymphoma in solid organ transplantation: a population-based cohort study in Australia
-
Na R, Laaksonen MA, Grulich AE, et al. Iatrogenic immunosuppression and risk of non-Hodgkin lymphoma in solid organ transplantation: a population-based cohort study in Australia. Br J Haematol. 2016;174:550-562.
-
(2016)
Br J Haematol
, vol.174
, pp. 550-562
-
-
Na, R.1
Laaksonen, M.A.2
Grulich, A.E.3
|