A Guinea pig model of Zika virus infection

Virology Journal

Volumn 14, Issue 1, 2017, Pages

  Kumar, Mukesh ^a   Krause, Keeton K ^a   Azouz, Francine ^a   Nakano, Eileen ^a   Nerurkar, Vivek R ^a  

^a UNIVERSITY OF HAWAII   (United States)

Author keywords

Animal models; Flavivirus; Guinea pigs; Immune response; Microcephaly; Pathogenesis; Zika virus

Indexed keywords

ANIMAL MODEL; ARTICLE; FEVER; GUINEA PIG; IMMUNE RESPONSE; JAPANESE ENCEPHALITIS VIRUS; NONHUMAN; PATHOGENESIS; PLAQUE ASSAY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VIREMIA; VIRUS NEUTRALIZATION; VIRUS TRANSMISSION; ZIKA FEVER; ANIMAL; BLOOD; DISEASE MODEL; GROWTH, DEVELOPMENT AND AGING; IMMUNOASSAY; IMMUNOLOGY; ISOLATION AND PURIFICATION; PATHOGENICITY; PATHOLOGY; REAL TIME POLYMERASE CHAIN REACTION; SERODIAGNOSIS; VIRAL PLAQUE ASSAY; VIROLOGY; VIRUS LOAD; ZIKA VIRUS;

CYTOKINE; NEUTRALIZING ANTIBODY; VIRUS ANTIBODY;

ANIMALS; ANTIBODIES, NEUTRALIZING; ANTIBODIES, VIRAL; CYTOKINES; DISEASE MODELS, ANIMAL; GUINEA PIGS; IMMUNOASSAY; NEUTRALIZATION TESTS; REAL-TIME POLYMERASE CHAIN REACTION; VIRAL LOAD; VIRAL PLAQUE ASSAY; VIREMIA; ZIKA VIRUS; ZIKA VIRUS INFECTION;

EID: 85018656529     PISSN: None     EISSN: 1743422X     Source Type: Journal    
DOI: 10.1186/s12985-017-0750-4     Document Type: Article

References (49)

1. Musso D, Gubler DJ. Zika Virus. Clin Microbiol Rev. 2016;29:487-524.
2. Klase ZA, Khakhina S, Schneider Ade B, Callahan MV, Glasspool-Malone J, Malone R. Zika fetal neuropathogenesis: etiology of a viral syndrome. PLoS Negl Trop Dis. 2016;10:e0004877.
3. Walker WL, Lindsey NP, Lehman JA, Krow-Lucal ER, Rabe IB, Hills SL, Martin SW, Fischer M, Staples JE. Zika virus disease cases - 50 states and the district of Columbia, January 1-July 31, 2016. MMWR Morb Mortal Wkly Rep. 2016;65:983-6.
4. Likos A, Griffin I, Bingham AM, Stanek D, Fischer M, White S, Hamilton J, Eisenstein L, Atrubin D, Mulay P, et al. Local mosquito-borne transmission of Zika virus - Miami-Dade and Broward counties, Florida, June-August 2016. MMWR Morb Mortal Wkly Rep. 2016;65:1032-8.
5. Culjat M, Darling SE, Nerurkar VR, Ching N, Kumar M, Min SK, Wong R, Grant L, Melish ME. Clinical and imaging findings in an infant with Zika embryopathy. Clin Infect Dis. 2016;63:805-11.
6. Kumar M, Ching L, Astern J, Lim E, Stokes AJ, Melish M, Nerurkar VR. Prevalence of antibodies to Zika virus in mothers from Hawaii Who delivered babies with and without Microcephaly between 2009-2012. PLoS Negl Trop Dis. 2016;10:e0005262.
7. Ferguson NM, Cucunuba ZM, Dorigatti I, Nedjati-Gilani GL, Donnelly CA, Basanez MG, Nouvellet P, Lessler J. EPIDEMIOLOGY. Countering the Zika epidemic in Latin America. Science. 2016;353:353-4.
8. Rossi SL, Tesh RB, Azar SR, Muruato AE, Hanley KA, Auguste AJ, Langsjoen RM, Paessler S, Vasilakis N, Weaver SC. Characterization of a novel Murine model to study Zika virus. Am J Trop Med Hyg. 2016;94(6):1362-9.
9. Lazear HM, Govero J, Smith AM, Platt DJ, Fernandez E, Miner JJ, Diamond MS. A mouse model of Zika virus pathogenesis. Cell Host Microbe. 2016;19:720-30.
10. Dowall SD, Graham VA, Rayner E, Atkinson B, Hall G, Watson RJ, Bosworth A, Bonney LC, Kitchen S, Hewson R. A susceptible mouse model for Zika virus infection. PLoS Negl Trop Dis. 2016;10:e0004658.
11. Aliota MT, Caine EA, Walker EC, Larkin KE, Camacho E, Osorio JE. Characterization of lethal zika virus infection in AG129 mice. PLoS Negl Trop Dis. 2016;10:e0004682.
12. Dick GW. Zika virus. II. Pathogenicity and physical properties. Trans R Soc Trop Med Hyg. 1952;46:521-34.
13. Faria NR, Azevedo Rdo S, Kraemer MU, Souza R, Cunha MS, Hill SC, Theze J, Bonsall MB, Bowden TA, Rissanen I, et al. Zika virus in the Americas: early epidemiological and genetic findings. Science. 2016;352:345-9.
14. Griffith BP, McCormick SR, Fong CK, Lavallee JT, Lucia HL, Goff E. The placenta as a site of cytomegalovirus infection in guinea pigs. J Virol. 1985;55:402-9.
15. Padilla-Carlin DJ, McMurray DN, Hickey AJ. The guinea pig as a model of infectious diseases. Comp Med. 2008;58:324-40.
16. Mess A. The Guinea pig placenta: model of placental growth dynamics. Placenta. 2007;28:812-5.
17. Manangeeswaran M, Ireland DD, Verthelyi D. Zika (PRVABC59) infection is associated with T cell infiltration and Neurodegeneration in CNS of Immunocompetent neonatal C57Bl/6 mice. PLoS Pathog. 2016;12:e1006004.
18. Kumar M, O'Connell M, Namekar M, Nerurkar VR. Infection with non-lethal West Nile virus Eg101 strain induces immunity that protects mice against the lethal West Nile virus NY99 strain. Viruses. 2014;6:2328-39.
19. Kumar M, Roe K, Nerurkar PV, Namekar M, Orillo B, Verma S, Nerurkar VR. Impaired virus clearance, compromised immune response and increased mortality in type 2 diabetic mice infected with West Nile virus. PLoS One. 2012;7:e44682.
20. Dowall SD, Bosworth A, Watson R, Bewley K, Taylor I, Rayner E, Hunter L, Pearson G, Easterbrook L, Pitman J, et al. Chloroquine inhibited Ebola virus replication in vitro but failed to protect against infection and disease in the in vivo guinea pig model. J Gen Virol. 2015;96:3484-92.
21. Kumar M, Roe K, Nerurkar PV, Orillo B, Thompson KS, Verma S, Nerurkar VR. Reduced immune cell infiltration and increased pro-inflammatory mediators in the brain of Type 2 diabetic mouse model infected with West Nile virus. J Neuroinflammation. 2014;11:80.
22. Kumar M, Nerurkar VR. Integrated analysis of microRNAs and their disease related targets in the brain of mice infected with West Nile virus. Virology. 2014;452-453:143-51.
23. Kumar M, Roe K, Orillo B, Muruve DA, Nerurkar VR, Gale Jr M, Verma S. Inflammasome adaptor protein apoptosis-associated speck-like protein containing CARD (ASC) is critical for the immune response and survival in west Nile virus encephalitis. J Virol. 2013;87:3655-67.
24. Kumar M, Belcaid M, Nerurkar VR. Identification of host genes leading to West Nile virus encephalitis in mice brain using RNA-seq analysis. Sci Rep. 2016;6:26350.
25. Lanciotti RS, Kosoy OL, Laven JJ, Velez JO, Lambert AJ, Johnson AJ, Stanfield SM, Duffy MR. Genetic and serologic properties of Zika virus associated with an epidemic, Yap State, Micronesia, 2007. Emerg Infect Dis. 2008;14:1232-9.
26. Kumar M, Roe K, O'Connell M, Nerurkar VR. Induction of virus-specific effector immune cell response limits virus replication and severe disease in mice infected with non-lethal West Nile virus Eg101 strain. J Neuroinflammation. 2015;12:178.
27. Namekar M, Kumar M, O'Connell M, Nerurkar VR. Effect of serum heat-inactivation and dilution on detection of anti-WNV antibodies in mice by West Nile virus E-protein microsphere immunoassay. PLoS One. 2012;7:e45851.
28. Dudley DM, Aliota MT, Mohr EL, Weiler AM, Lehrer-Brey G, Weisgrau KL, Mohns MS, Breitbach ME, Rasheed MN, Newman CM, et al. A rhesus macaque model of Asian-lineage Zika virus infection. Nat Commun. 2016;7:12204.
29. Styer LM, Kent KA, Albright RG, Bennett CJ, Kramer LD, Bernard KA. Mosquitoes inoculate high doses of West Nile virus as they probe and feed on live hosts. PLoS Pathog. 2007;3:1262-70.
30. Cox J, Mota J, Sukupolvi-Petty S, Diamond MS, Rico-Hesse R. Mosquito bite delivery of dengue virus enhances immunogenicity and pathogenesis in humanized mice. J Virol. 2012;86:7637-49.
31. Dutra HL, Rocha MN, Dias FB, Mansur SB, Caragata EP, Moreira LA. Wolbachia blocks currently circulating Zika virus isolates in Brazilian Aedes Aegypti mosquitoes. Cell Host Microbe. 2016;19:771-4.
32. Li XF, Dong HL, Huang XY, Qiu YF, Wang HJ, Deng YQ, Zhang NN, Ye Q, Zhao H, Liu ZY, et al. Characterization of a 2016 clinical isolate of Zika virus in Non-human primates. EBioMed. 2016;12:170-7.
33. Kaushik DK, Gupta M, Kumawat KL, Basu A. NLRP3 inflammasome: key mediator of neuroinflammation in murine Japanese encephalitis. PLoS One. 2012;7:e32270.
34. King NJ, Getts DR, Getts MT, Rana S, Shrestha B, Kesson AM. Immunopathology of flavivirus infections. Immunol Cell Biol. 2007;85:33-42.
35. Terry RL, Getts DR, Deffrasnes C, van Vreden C, Campbell IL, King NJ. Inflammatory monocytes and the pathogenesis of viral encephalitis. J Neuroinflammation. 2012;9:270.
36. Fredericksen BL. The neuroimmune response to West Nile virus. J Neurovirol. 2014;20:113-21.
37. Dinarello CA, Novick D, Kim S, Kaplanski G. Interleukin-18 and IL-18 binding protein. Front Immunol. 2013;4:289.
38. Keyel PA. How is inflammation initiated? Individual influences of IL-1, IL-18 and HMGB1. Cytokine. 2014;69:136-45.
39. Kanneganti TD. Central roles of NLRs and inflammasomes in viral infection. Nat Rev Immunol. 2010;10:688-98.
40. Chen H, Yang X, Du J, Lu M. Interleukin-18 gene polymorphisms and risk of recurrent pregnancy loss: a systematic review and meta-analysis. J Obstet Gynaecol Res. 2015;41:1506-13.
41. Yue J, Tong Y, Zhou J, Liu Q, Yang J. Genetic variant in interleukin-18 is associated with idiopathic recurrent miscarriage in Chinese Han population. Int J Mol Sci. 2015;16:4180-9.
42. Arenas-Ramirez N, Woytschak J, Boyman O. Interleukin-2: biology, design and application. Trends Immunol. 2015;36:763-77.
43. Bell TM, Field EJ, Narang HK. Zika virus infection of the central nervous system of mice. Arch Gesamte Virusforsch. 1971;35:183-93.
44. Inouye S, Matsuno S, Tsurukubo Y. "Original antigenic sin" phenomenon in experimental flavivirus infections of guinea pigs: studies by enzyme-linked immunosorbent assay. Microbiol Immunol. 1984;28:569-74.
45. Lee HH, Hong SK, Yoon SH, Jang SJ, Bahk YY, Song MD, Park PJ, Lee KH, Kim CG, Kim B, et al. Immunogenicity of Japanese encephalitis virus envelope protein by Hyphantria cunea nuclear polyhedrosis virus vector in guinea pig. Appl Biochem Biotechnol. 2012;167:259-69.
46. Chan KW, Watanabe S, Kavishna R, Alonso S, Vasudevan SG. Animal models for studying dengue pathogenesis and therapy. Antiviral Res. 2015;123:5-14.
47. Bakardjiev AI, Stacy BA, Fisher SJ, Portnoy DA. Listeriosis in the pregnant guinea pig: a model of vertical transmission. Infect Immun. 2004;72:489-97.
48. Wicher K, Baughn RE, Wicher V, Nakeeb S. Experimental congenital syphilis: guinea pig model. Infect Immun. 1992;60:271-7.
49. Griffith BP, Lucia HL, Tillbrook JL, Hsiung GD. Enhancement of cytomegalovirus infection during pregnancy in guinea pig. J Infect Dis. 1983;147:990-8.