The Microbiome of the Prostate Tumor Microenvironment [Figure presented]

European Urology

Volumn 72, Issue 4, 2017, Pages 625-631

  Cavarretta, Ilaria ^a   Ferrarese, Roberto ^b   Cazzaniga, Walter ^a   Saita, Diego ^a   Lucianò, Roberta ^a   Ceresola, Elisa R ^c   Locatelli, Irene ^a   Visconti, Laura ^a   Lavorgna, Giovanni ^a   Briganti, Alberto ^a,b   Nebuloni, Manuela ^d   Doglioni, Claudio ^a,b   Clementi, Massimo ^a,b   Montorsi, Francesco ^a,b   Canducci, Filippo ^a,c   Salonia, Andrea ^a,b  

^a SAN RAFFAELE HOSPITAL   (Italy)

^b VITA SALUTE SAN RAFFAELE UNIVERSITY   (Italy)

^c UNIVERSITY OF INSUBRIA   (Italy)

^d UNIVERSITY OF MILAN   (Italy)

Author keywords

Microbiome; Propionibacterium acnes; Prostate cancer; Staphylococcus spp.; Streptococcus spp.; Tumor microenvironment

Indexed keywords

ACTINOBACTERIA; ARTICLE; BACTERIAL LOAD; CANCER SURGERY; CLINICAL ARTICLE; COHORT ANALYSIS; FIRMICUTES; HUMAN; HUMAN TISSUE; MALE; MICROBIOME; NONHUMAN; OUTCOME ASSESSMENT; PATHOGENESIS; PRIORITY JOURNAL; PROPIONIBACTERIUM; PROSTATE CANCER; PROSTATECTOMY; PROTEOBACTERIA; PYROSEQUENCING; STAPHYLOCOCCUS; TAXONOMY; TUMOR MICROENVIRONMENT; BACTERIUM; BACTERIUM IDENTIFICATION; CLASSIFICATION; GENETICS; HIGH THROUGHPUT SEQUENCING; ISOLATION AND PURIFICATION; MICROBIOLOGY; MICROFLORA; PATHOLOGY; PHYLOGENY; PROCEDURES; PROSTATE TUMOR;

BACTERIAL DNA;

BACTERIA; BACTERIAL LOAD; BACTERIAL TYPING TECHNIQUES; DNA, BACTERIAL; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; MALE; MICROBIOTA; PHYLOGENY; PROSTATECTOMY; PROSTATIC NEOPLASMS; TUMOR MICROENVIRONMENT;

EID: 85018632944     PISSN: 03022838     EISSN: 18737560     Source Type: Journal    
DOI: 10.1016/j.eururo.2017.03.029     Document Type: Article

References (30)

1. Malvezzi, M., Carioli, G., Bertuccio, P., et al. European cancer mortality predictions for the year 2016 with focus on leukaemias. Ann Oncol 27 (2016), 725–731.
2. Sfanos, K.S., Isaacs, W.B., De Marzo, A.M., Infections and inflammation in prostate cancer. Am J Clin Exp Urol 1 (2013), 3–11.
3. De Marzo, A.M., Platz, E.A., Sutcliffe, S., et al. Inflammation in prostate carcinogenesis. Nat Rev Cancer 7 (2007), 256–269.
4. Peisch, S.F., Van Blarigan, E.L., Chan, J.M., Stampfer, M.J., Kenfield, S.A., Prostate cancer progression and mortality: a review of diet and lifestyle factors. World J Urol 35 (2017), 867–874.
5. Hullar, M.A., Burnett-Hartman, A.N., Lampe, J.W., Gut microbes, diet, and cancer. Cancer Treat Res 159 (2014), 377–399.
6. Holmes, E., Li, J.V., Athanasiou, T., Ashrafian, H., Nicholson, J.K., Understanding the role of gut microbiome-host metabolic signal disruption in health and disease. Trends Microbiol 19 (2011), 349–359.
7. Yatsunenko, T., Rey, F.E., Manary, M.J., et al. Human gut microbiome viewed across age and geography. Nature 486 (2012), 222–227.
8. Giorgetti, G., Brandimarte, G., Fabiocchi, F., et al. Interactions between innate immunity, microbiota, and probiotics. J Immunol Res, 2015, 2015, 501361.
9. van Olden, C., Groen, A.K., Nieuwdorp, M., Role of intestinal microbiome in lipid and glucose metabolism in diabetes mellitus. Clin Ther 37 (2015), 1172–1177.
10. Cox, A.J., West, N.P., Cripps, A.W., Obesity, inflammation, and the gut microbiota. Lancet Diabetes Endocrinol 3 (2015), 207–215.
11. Ley, R.E., Obesity and the human microbiome. Curr Opin Gastroenterol 26 (2010), 5–11.
12. Giongo, A., Gano, K.A., Crabb, D.B., et al. Toward defining the autoimmune microbiome for type 1 diabetes. ISME J 5 (2011), 82–91.
13. Belkaid, Y., Hand, T.W., Role of the microbiota in immunity and inflammation. Cell 157 (2014), 121–141.
14. Shinohara, D.B., Vaghasia, A.M., Yu, S.H., et al. A mouse model of chronic prostatic inflammation using a human prostate cancer-derived isolate of Propionibacterium acnes. Prostate 73 (2013), 1007–1015.
15. Cohen, R.J., Shannon, B.A., McNeal, J.E., Shannon, T., Garrett, K.L., Propionibacterium acnes associated with inflammation in radical prostatectomy specimens: a possible link to cancer evolution?. J Urol 173 (2005), 1969–1974.
16. Alfano, M., Canducci, F., Nebuloni, M., Clementi, M., Montorsi, F., Salonia, A., The interplay of extracellular matrix and microbiome in urothelial bladder cancer. Nat Rev Urol 13 (2016), 77–90.
17. Caini, S., Gandini, S., Dudas, M., Bremer, V., Severi, E., Gherasim, A., Sexually transmitted infections and prostate cancer risk: a systematic review and meta-analysis. Cancer Epidemiol 38 (2014), 329–338.
18. Yoon, B.I., Kim, S., Han, D.S., et al. Acute bacterial prostatitis: how to prevent and manage chronic infection?. J Infect Chemother 18 (2012), 444–450.
19. Zitvogel, L., Galluzzi, L., Viaud, S., et al. Cancer and the gut microbiota: an unexpected link. Sci Transl Med, 7, 2015, 271ps1.
20. Structure, function and diversity of the healthy human microbiome. Nature 2012;486:207-14. http://dx.doi.org/10.1038/nature11234.
21. Mandar, R., Microbiota of male genital tract: impact on the health of man and his partner. Pharmacol Res 69 (2013), 32–41.
22. Sfanos, K.S., Sauvageot, J., Fedor, H.L., Dick, J.D., De Marzo, A.M., Isaacs, W.B., A molecular analysis of prokaryotic and viral DNA sequences in prostate tissue from patients with prostate cancer indicates the presence of multiple and diverse microorganisms. Prostate 68 (2008), 306–320.
23. Gospodarowicz, M., Wittekind, C., Sobin, L., TNM classification of malignant tumors. 2009, Wiley-Blackwell, Hoboken, NJ.
24. Umbehr, M.H., Gurel, B., Murtola, T.J., et al. Intraprostatic inflammation is positively associated with serum PSA in men with PSA <4 ng ml(-1), normal DRE and negative for prostate cancer. Prostate Cancer Prostatic Dis 18 (2015), 264–269.
25. Shannon, B.A., Cohen, R.J., Garrett, K.L., Polymerase chain reaction-based identification of Propionibacterium acnes types isolated from the male urinary tract: evaluation of adolescents, normal adults and men with prostatic pathology. BJU Int 98 (2006), 388–392.
26. Thomason, J.L., Schreckenberger, P.C., Spellacy, W.N., Riff, L.J., LeBeau, L.J., Clinical and microbiological characterization of patients with nonspecific vaginosis associated with motile, curved anaerobic rods. J Infect Dis 149 (1984), 801–809.
27. Ohkusa, T., Koido, S., Intestinal microbiota and ulcerative colitis. J Infect Chemother 21 (2015), 761–768.
28. Cipe, G., Idiz, U.O., Firat, D., Bektasoglu, H., Relationship between intestinal microbiota and colorectal cancer. World J Gastrointest Oncol 7 (2015), 233–240.
29. Souza, M.C., dos Santos, L.S., Sousa, L.P., et al. Biofilm formation and fibrinogen and fibronectin binding activities by Corynebacterium pseudodiphtheriticum invasive strains. Antonie Van Leeuwenhoek 107 (2015), 1387–1399.
30. Riemersma, W.A., van der Schee, C.J., van der Meijden, W.I., Verbrugh, H.A., van Belkum, A., Microbial population diversity in the urethras of healthy males and males suffering from nonchlamydial, nongonococcal urethritis. J Clin Microbiol 41 (2003), 1977–1986.