High copy wildtype human 1N4R tau expression promotes early pathological tauopathy accompanied by cognitive deficits without progressive neurofibrillary degeneration

Acta neuropathologica communications

Volumn 3, Issue , 2015, Pages 33-

  Wheeler, Jeanna M ^a   McMillan, Pamela J ^a,b,c   Hawk, Michele ^a   Iba, Michiyo ^a   Robinson, Linda ^a   Xu, George J ^a   Dombroski, Beth A ^a   Jeong, Doori ^a   Dichter, Marc A ^a   Juul, Halvor ^a   Loomis, Elaine ^a   Raskind, Murray ^b,c   Leverenz, James B ^c   Trojanowski, John Q ^a   Lee, Virginia M Y ^a   Schellenberg, Gerard D ^a   Kraemer, Brian C ^a,c  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b VA PUGET SOUND HEALTH CARE SYSTEM   (United States)

^c LERNER RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MAPT PROTEIN, HUMAN; TAU PROTEIN;

AGE; ANALYSIS OF VARIANCE; ANIMAL; BRAIN; C57BL MOUSE; COGNITION DISORDERS; COMPLICATION; COPY NUMBER VARIATION; DISEASE COURSE; ELECTROENCEPHALOGRAPHY; EXPLORATORY BEHAVIOR; GENETICS; HUMAN; MAZE TEST; METABOLISM; MOTOR ACTIVITY; MOUSE; MUSCLE STRENGTH; NEUROFIBRILLARY TANGLE; PATHOLOGY; PHYSIOLOGY; TAUOPATHY; TRANSGENIC MOUSE;

AGE FACTORS; ANALYSIS OF VARIANCE; ANIMALS; BRAIN; COGNITION DISORDERS; DISEASE PROGRESSION; DNA COPY NUMBER VARIATIONS; ELECTROENCEPHALOGRAPHY; EXPLORATORY BEHAVIOR; HUMANS; MAZE LEARNING; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MOTOR ACTIVITY; MUSCLE STRENGTH; NEUROFIBRILLARY TANGLES; TAU PROTEINS; TAUOPATHIES;

EID: 85018237568     PISSN: None     EISSN: 20515960     Source Type: Journal    
DOI: 10.1186/s40478-015-0210-6     Document Type: Article

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