Biochemical and Functional Characterization of RNF213 (Mysterin) R4810K, a Susceptibility Mutation of Moyamoya Disease, in Angiogenesis In Vitro and In Vivo

Journal of the American Heart Association

Volumn 4, Issue 7, 2015, Pages

  Kobayashi, Hatasu ^a   Matsuda, Yoshiko ^a   Hitomi, Toshiaki ^a   Okuda, Hiroko ^a   Shioi, Hirotomo ^a   Matsuda, Tetsuya ^a   Imai, Hirohiko ^a   Sone, Masakatsu ^a   Taura, Daisuke ^a   Harada, Kouji H ^a   Habu, Toshiyuki ^a   Takagi, Yasushi ^a   Miyamoto, Susumu ^a   Koizumi, Akio ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

ATPase; interferon; moyamoya disease; RNF213; transgenic mouse

Indexed keywords

ADENOSINE TRIPHOSPHATASE; ADENOSINE TRIPHOSPHATE; ANGIOGENESIS INHIBITOR; ANGIOGENIC FACTOR; AUTACOID; RNF213 PROTEIN, HUMAN; RNF213 PROTEIN, MOUSE; UBIQUITIN PROTEIN LIGASE;

ANGIOGENESIS; ANIMAL; BINDING COMPETITION; BINDING SITE; BRAIN ARTERY; C57BL MOUSE; CELL MOTION; CELL PROLIFERATION; COMPLICATION; DISEASE MODEL; DOSE RESPONSE; DRUG EFFECTS; ENDOTHELIUM CELL; ENZYMOLOGY; GENETIC PREDISPOSITION; GENETIC TRANSFECTION; GENETICS; HEK293 CELL LINE; HELA CELL LINE; HUMAN; HYDROLYSIS; HYPOXIA; METABOLISM; MOYAMOYA DISEASE; MUTATION; PATHOPHYSIOLOGY; PHENOTYPE; PROTEIN MOTIF; SMOOTH MUSCLE CELL; TIME FACTOR; TRANSGENIC MOUSE; UMBILICAL VEIN ENDOTHELIAL CELL;

ADENOSINE TRIPHOSPHATASES; ADENOSINE TRIPHOSPHATE; AMINO ACID MOTIFS; ANGIOGENESIS INDUCING AGENTS; ANGIOGENESIS INHIBITORS; ANIMALS; BINDING SITES; BINDING, COMPETITIVE; CELL MOVEMENT; CELL PROLIFERATION; CEREBRAL ARTERIES; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIAL CELLS; GENETIC PREDISPOSITION TO DISEASE; HEK293 CELLS; HELA CELLS; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; HYDROLYSIS; HYPOXIA; INFLAMMATION MEDIATORS; MICE, INBRED C57BL; MICE, TRANSGENIC; MOYAMOYA DISEASE; MUTATION; MYOCYTES, SMOOTH MUSCLE; NEOVASCULARIZATION, PHYSIOLOGIC; PHENOTYPE; TIME FACTORS; TRANSFECTION; UBIQUITIN-PROTEIN LIGASES;

EID: 85018214590     PISSN: None     EISSN: 20479980     Source Type: Journal    
DOI: 10.1161/JAHA.115.002146     Document Type: Article

References (0)