Environmental emission of multiresistant Escherichia coli carrying the colistin resistance gene mcr-1 from German swine farms

Journal of Antimicrobial Chemotherapy

Volumn 72, Issue 5, 2017, Pages 1289-1292

  Guenther, Sebastian ^a   Falgenhauer, Linda ^b   Semmler, Torsten ^c   Imirzalioglu, Can ^b   Chakraborty, Trinad ^b   Roesler, Uwe ^a   Roschanski, Nicole ^a  

^a FREIE UNIVERSITÄT BERLIN   (Germany)

^b JUSTUS LIEBIG UNIVERSITY   (Germany)

^c ROBERT KOCH INSTITUTE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

COLISTIN; MCR 1 PROTEIN; PEPTIDES AND PROTEINS; UNCLASSIFIED DRUG; ANTIINFECTIVE AGENT; ESCHERICHIA COLI PROTEIN; MCR-1 PROTEIN, E COLI;

ANTIBIOTIC RESISTANCE; ANTIBIOTIC THERAPY; ARTICLE; BACTERIUM CULTURE; BACTERIUM ISOLATE; ESCHERICHIA COLI; GENOTYPE; GERMANY; HOUSE FLY; MANURE; NONHUMAN; PHYLOGENY; PLASMID; PORCINE MODEL; REAL TIME POLYMERASE CHAIN REACTION; SINGLE NUCLEOTIDE POLYMORPHISM; AGRICULTURAL LAND; ANIMAL; CLASSIFICATION; DOG; ESCHERICHIA COLI INFECTION; FECES; GENETICS; HUMAN; ISOLATION AND PURIFICATION; MICROBIAL SENSITIVITY TEST; MICROBIOLOGY; MULTIDRUG RESISTANCE; PIG; TRANSMISSION;

ANIMALS; ANTI-BACTERIAL AGENTS; COLISTIN; DOGS; DRUG RESISTANCE, MULTIPLE, BACTERIAL; ESCHERICHIA COLI; ESCHERICHIA COLI INFECTIONS; ESCHERICHIA COLI PROTEINS; FARMS; FECES; GENOTYPE; GERMANY; HUMANS; MANURE; MICROBIAL SENSITIVITY TESTS; PHYLOGENY; PLASMIDS; REAL-TIME POLYMERASE CHAIN REACTION; SWINE;

EID: 85018190033     PISSN: 03057453     EISSN: 14602091     Source Type: Journal    
DOI: 10.1093/jac/dkw585     Document Type: Article

References (20)

1. Liu YY, Wang Y, Walsh TR et al. Emergence of plasmid-mediated colistin resistance mechanism MCR-1 in animals and human beings in China: a microbiological andmolecular biological study. Lancet Infect Dis 2016; 2: 161-8
2. Skov RL, Monnet DL. Plasmid-mediated colistin resistance (mcr-1 gene): threemonths later, the story unfolds. Euro Surveill 2016; 21: 30155
3. EMA. Updated Advice on the Use of Colistin Products in Animals within the European Union: Development of Resistance and Possible Impact on Human and Animal Health. 2016. http://www. ema. europa. eu/docs/en_GB/docu ment_library/Press_release/2016/07/WC500211081. pdf
4. von Salviati C, Laube H, Guerra B et al. Emission of ESBL/AmpC-producing Escherichia coli from pig fattening farms to surrounding areas. Vet Microbiol 2015; 175: 77-84
5. Roschanski N, Friese A, von Salviati-Claudius C et al. Prevalence of carbapenemase producing Enterobacteriaceae isolated from German pig-fattening farms during the years 2011-2013. Vet Microbiol 2015; doi: 10. 1016/j. vetmic. 2015. 11. 030
6. Irrgang A, Roschanski N, Tenhagen BA et al. Prevalence of mcr-1 in E. coli from livestock and food in Germany, 2010-2015. PLoS ONE 2016; 11: e0159863
7. Aziz RK, Bartels D, Best AA et al. The RAST server: rapid annotations using subsystems technology. BMC Genomics 2008; 9: 75
8. Larsen MV, Cosentino S, Rasmussen S et al. Multilocus sequence typing of total-genome-sequenced bacteria. JClinMicrobiol 2012; 50: 1355-61
9. Zankari E, Hasman H, Cosentino S et al. Identification of acquired antimicrobial resistance genes. J Antimicrob Chemother 2012; 67: 2640-4
10. Carattoli A, Zankari E, Garcia-Fernandez A et al. In silico detection and typing of plasmids using PlasmidFinder and plasmid multilocus sequence typing. Antimicrob Agents Chemother 2014; 58: 3895-903
11. Alikhan NF, Petty NK, Ben Zakour NL et al. BLAST Ring Image Generator (BRIG): simple prokaryote genome comparisons. BMC Genomics 2011; 12: 402
12. Treangen TJ, Ondov BD, Koren S et al. The Harvest suite for rapid coregenome alignment and visualization of thousands of intraspecific microbial genomes. GenomeBiol 2014; 15: 524
13. VeldmanK, van Essen-Zandbergen A, RapalliniMet al. Location of colistin resistance gene mcr-1 in Enterobacteriaceae from livestock and meat. J Antimicrob Chemother 2016; 71: 2340-2
14. Xavier BB, Lammens C, Butaye P et al. Complete sequence of an IncFII plasmid harbouring the colistin resistance gene mcr-1 isolated from Belgian pig farms. JAntimicrobChemother 2016; 71: 2342-4
15. Bernasconi OJ, Kuenzli E, Pires J et al. Travelers can import colistinresistant Enterobacteriaceae, including those possessing the plasmidmediatedmcr-gene. Antimicrob Agents Chemother 2016; 60: 5080-4
16. Xavier BB, Lammens C, Ruhal R et al. Identification of a novel plasmidmediated colistin-resistance gene, mcr-2, in Escherichia coli, Belgium, June 2016 Euro Surveill 2016; 21: 30280
17. Fernandes MR, McCulloch JA, Vianello MA et al. First report of the globally disseminated IncX4 plasmid carrying the mcr-1 gene in a colistin-resistant Escherichia coli ST101 isolated from a human infection in Brazil. Antimicrob Agents Chemother 2016; 60: 6415-7
18. Zhang WJ, Wang XM, Dai L et al. Novel conjugative plasmid from Escherichia coli of swine origin that coharbors the multiresistance gene cfr and the extended-spectrum-β-lactamase gene blaCTX-M-14b. Antimicrob Agents Chemother 2015; 59: 1337-40
19. Grad YH, Lipsitch M, Feldgarden M et al. Genomic epidemiology of the Escherichia coli O104:H4 outbreaks in Europe, 2011. Proc Natl Acad Sci U S A 2012; 109: 3065-70
20. de Been M, Lanza VF, de Toro M et al. Dissemination of cephalosporin resistance genes between Escherichia coli strains from farm animals and humans by specific plasmid lineages. PLoS Genet 2014; 10: e1004776