Molecular antibiogram in diagnostic clinical microbiology: Advantages and challenges

Future Microbiology

Volumn 12, Issue 5, 2017, Pages 361-364

  Arena, Fabio ^a   Giani, Tommaso ^a   Pollini, Simona ^b   Viaggi, Bruno ^c   Pecile, Patrizia ^c   Rossolini, Gian Maria ^b,c  

^a UNIVERSITY OF SIENA   (Italy)

^b UNIVERSITY OF FLORENCE   (Italy)

^c CAREGGI UNIVERSITY HOSPITAL   (Italy)

Author keywords

Antimicrobial susceptibility testing; Diagnostic microbiology; Molecular detection

Indexed keywords

ANTIBIOTIC SENSITIVITY; DIAGNOSTIC MICROBIOLOGY; MEDICAL TECHNOLOGY; MICROBIOLOGY; MOLECULAR ANTIBIOGRAM; PRIORITY JOURNAL; REVIEW; WORKFLOW; ANTIBIOTIC RESISTANCE; BACTERIAL INFECTION; DIAGNOSTIC TEST; HOSPITAL; HUMAN; INAPPROPRIATE PRESCRIBING; MICROBIAL SENSITIVITY TEST; MOLECULAR DIAGNOSIS; PROCEDURES;

ANTIINFECTIVE AGENT;

ANTI-BACTERIAL AGENTS; BACTERIAL INFECTIONS; DIAGNOSTIC TESTS, ROUTINE; DRUG RESISTANCE, BACTERIAL; HOSPITALS; HUMANS; INAPPROPRIATE PRESCRIBING; MICROBIAL SENSITIVITY TESTS; MOLECULAR DIAGNOSTIC TECHNIQUES;

EID: 85017558002     PISSN: 17460913     EISSN: 17460921     Source Type: Journal    
DOI: 10.2217/fmb-2017-0019     Document Type: Review

References (18)

1. Courvalin P, Leclercq R, Rice LB. Antibiogram (3rd Edition). ASM Press, Washington, DC, USA (2010).
2. Barlam TF, Cosgrove SE, Abbo LM et al. Implementing an antibiotic stewardshipprogram: Guidelines by the InfectiousDiseases Society of America and the Societyfor Healthcare Epidemiology of America. Clin. Infect. Dis. 62(10), e51-e77 (2016).
3. Gazi MA, Islam MR, Kibria MG, Mahmud Z. General and advanced diagnostic tools todetect Mycobacterium tuberculosis and theirdrug susceptibility: A review. Eur. J. Clin. Microbiol. Infect. Dis. 34(5), 851-861(2015).
4. Mégraud F, Bénéjat L, Ontsira Ngoyi EN, Lehours P. Molecular approaches to identifyHelicobacter pylori antimicrobial resistance. Gastroenterol. Clin. North Am. 44(3), 577-596 (2015).
5. Van Belkum A, Dunne WM Jr. Nextgenerationantimicrobial susceptibilitytesting. J. Clin. Microbiol. 51(7), 2018-2024(2013).
6. Timbrook TT, Morton JB, McConeghy KW, Caffrey AR, Mylonakis E, LaPlante KL. Theeffect of molecular rapid diagnostic testing onclinical outcomes in bloodstream infections: Asystematic review and meta-analysis. Clin. Infect. Dis. 64(1), 15-23 (2017).
7. Glupczynski Y, Evrard S, Ote I et al. Evaluation of two new commercialimmunochromatographic assays for the rapiddetection of OXA-48 and KPCcarbapenemases from cultured bacteria. J. Antimicrob. Chemother. 71(5), 1217-1222(2016).
8. Van Belkum A, Chatellier S, Girard V, PincusD, Deol P, Dunne WM Jr. Progress inproteomics for clinical microbiology:MALDI-TOF MS for microbial speciesidentification and more. Expert Rev. Proteomics 12(6), 595-605 (2015).
9. Arena F, Viaggi B, Galli L, Rossolini GM. Antibiotic susceptibility testing: Present andfuture. Pediatr. Infect. Dis. J. 34(10), 1128-1130 (2015).
10. Opota O, Jaton K, Greub G. Microbialdiagnosis of bloodstream infection: Towardsmolecular diagnosis directly from blood. Clin. Microbiol. Infect. 21(4), 323-331(2015).
11. Bauer KA, West JE, Balada-Llasat J-M, Pancholi P, Stevenson KB, Goff DA. Anantimicrobial stewardship program's impactwith rapid polymerase chain reactionmethicillin-resistant Staphylococcus aureus/S. aureus blood culture test in patients withS. aureus bacteremia. Clin. Infect. Dis. 51(9), 1074-1080 (2010).
12. Sango A, McCarter YS, Johnson D, Ferreira J, Guzman N, Jankowski CA. Stewardshipapproach for optimizing antimicrobialtherapy through use of a rapid microarrayassay on blood cultures positive forEnterococcus species. J. Clin. Microbiol. 51(12), 4008-4011 (2013).
13. Stevenson M, Pandor A, Martyn-St James Met al. Sepsis: The LightCycler SeptiFast TestMGRADE® , SepsiTest™ and IRIDICA BACBSI assay for rapidly identifying bloodstreambacteria and fungi-a systematic review andeconomic evaluation. Health Technol. Assess. 20(46), 1-246 (2016).
14. Gordon NC, Price JR, Cole K et al. Prediction of Staphylococcus aureusantimicrobial resistance by whole-genomesequencing. J. Clin. Microbiol. 52(4), 1182-1191 (2014).
15. Aanensen DM, Feil EJ, Holden MT et al. Whole-genome sequencing for routinepathogen surveillance in public health: Apopulation snapshot of invasive Staphylococcusaureus in Europe. MBio 7(3), doi:10. 1128/mBio. 00444-16 (2016).
16. Heil EL, Johnson JK. Impact of CLSIbreakpoint changes on microbiologylaboratories and antimicrobial stewardshipprograms. J. Clin. Microbiol. 54(4), 840-844(2016).
17. Bassetti M, Carnelutti A, Peghin M. Patientspecific risk stratification for antimicrobialresistance and possible treatment strategies inGram-negative bacterial infections. ExpertRev. Anti-Infect. Ther. 15(1), 55-65 (2017).
18. Valenzuela-Sanches F, Valenzuela-Méndez B, Rodríguez-Gutiérrez JF. New role ofbiomarkers: Mid-regional proadrenomedullin, the biomarker of organfailure. Ann. Transl. Med. 4(17), 329 (2016).