An LC–MS/MS method for the determination of antibiotic residues in distillers grains

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 1053, Issue , 2017, Pages 81-86

  Duelge, Kaleb J ^a   Nishshanka, Upul ^a   De Alwis, Hemakanthi G ^a  

^a CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

Author keywords

Antibiotics; Antimicrobial resistance; Distillers grain; Feed; Residue analysis; Tandem mass spectrometry

Indexed keywords

ACETONITRILE; CALIBRATION; DRUG PRODUCTS; ETHANOL; EXTRACTION; FEEDING; GRAIN (AGRICULTURAL PRODUCT); MASS SPECTROMETRY; MICROORGANISMS; PHASE SEPARATION; SPECTROMETRY; SURVEYS;

ANTIMICROBIAL RESISTANCES; DISTILLERS GRAINS; LIMITS OF QUANTITATIONS; QUANTITATIVE DETERMINATIONS; RELATIVE STANDARD DEVIATIONS; RESIDUE ANALYSIS; SOLID PHASE EXTRACTION CARTRIDGES; TANDEM MASS SPECTROMETRY;

ANTIBIOTICS;

DALFOPRISTIN; ERYTHROMYCIN; PENICILLIN G; VIRGINIAMYCIN S; ACETONITRILE; ACETONITRILE DERIVATIVE; ANTIINFECTIVE AGENT; HEXANE; MIKAMYCIN B; N-HEXANE; VIRGINIAMYCIN; VIRGINIAMYCIN FACTOR S1;

ANIMAL FOOD; ANTIBIOTIC RESISTANCE; ARTICLE; CONTROLLED STUDY; DRUG DETERMINATION; LIMIT OF QUANTITATION; LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY; NONHUMAN; PRIORITY JOURNAL; QUALITY CONTROL; SOLID PHASE EXTRACTION; SOLVENT EXTRACTION; STANDARD; TANDEM MASS SPECTROMETRY; ANALYSIS; ANIMAL; CHEMISTRY; FOOD GRAIN; LIMIT OF DETECTION; LIQUID CHROMATOGRAPHY; PROCEDURES; VALIDATION STUDY;

ACETONITRILES; ANIMAL FEED; ANIMALS; ANTI-BACTERIAL AGENTS; CHROMATOGRAPHY, LIQUID; EDIBLE GRAIN; ERYTHROMYCIN; HEXANES; LIMIT OF DETECTION; PENICILLIN G; SOLID PHASE EXTRACTION; STREPTOGRAMIN A; STREPTOGRAMIN GROUP B; TANDEM MASS SPECTROMETRY; VIRGINIAMYCIN;

EID: 85017461036     PISSN: 15700232     EISSN: 1873376X     Source Type: Journal    
DOI: 10.1016/j.jchromb.2017.03.037     Document Type: Article

References (13)

1. [1] FY 2010 Nationwide Survey of Distillers Grains for Antibiotic Residues. 2009 http://www.fda.gov/AnimalVeterinary/Products/AnimalFoodFeeds/Contaminants/ucm190907.htm (Accessed January 3, 2017).
2. [2] A Guide to Distiller's Dried Grains with Solubles (DDGS). 3rd edition, 2012, US Grains Council.
3. [3] Agricultural Marketing Resource Center, Cooperative Extension Service, Iowa State University of Science and Technology, Ames, Iowa, 2016. http://www.extension.iastate.edu/agdm/crops/outlook/dgsbalancesheet.pdf (Accessed January 3, 2017).
4. [4] Renewable Fuels Association, Food vs. Fuel. 2017, Renewable Fuels Association http://www.ethanolrfa.org/consumers/food-vs-fuel/ (Accessed January 3, 2017).
5. [5] Distillers Grains Technology Council, 2014, http://www.distillersgrains.org/grains/availability.html (Accessed January 3, 2017).
6. [6] Feeding De-Oiled Distillers Grains in Growing and Finishing Diets. 2013, University of Nebraska, Lincoln http://newsroom.unl.edu/announce/beef/2155/12419 (Accessed January 3, 2017).
7. [7] FDA/Laboratory Information Bulletin #4438: Analysis of Antibiotics in Distillers Grains Using Liquid Chromatography and Ion Trap Tandem Mass Spectrometry. 2009 http://www.fda.gov/downloads/AnimalVeterinary/ScienceResearch/ToolsResources/UCM182280.pdf (Accessed January 3, 2017).
8. [8] De Alwis, H., Heller, D.N., Multiclass, multiresidue method for the detection of antibiotic residues in distillers grains by liquid chromatography and ion trap tandem mass spectrometry. J. Chromatogr. A, 1217–1218, 2010, 3076.
9. [9] Botsoglu, N.A., Fletouris, D.J., Drug Residues in Foods. 2001, Marcel Decker AG.
10. [10] Schwartz, M.A., Mechanism of degradation of penicillin G in acidic solution. J. Pharm. Sci. 54–63 (1965), 472–473.
11. [11] Wang, J., Turnipseed, S.B., Chemical analysis: quantitative and confirmatory methods. Wang, J., MacNeil, J.D., Kay, J.F., (eds.) Chemical Analysis of Antibiotic Residues in Food, 2011, John Wiley & Sons, Inc., New Jersey, 187–198.
12. [12] Guidelines for the Validation of Chemical Methods for the FDA FVM Program. 2nd edition, 2015, US Food & Drug Administration, Office of Foods and Veterinary Medicine http://www.fda.gov/downloads/ScienceResearch/FieldScience/UCM273418.pdf (April).
13. [13] Youden, W.J., H.Steiner, E., Statistical Manual of the Association of Official Analytical Chemists. 1975, AOAC International, 33–36.