-
2
-
-
84922519772
-
Efficacy and safety of a fixed-ratio combination of insulin degludec and liraglutide (IDegLira) compared with its components given alone: results of a phase 3, open-label, randomised, 26-week, treat-to-target trial in insulin-naive patients with type 2 diabetes
-
COI: 1:CAS:528:DC%2BC2MXhtlWhsrk%3D, PID: 25190523
-
S.C. Gough, B. Bode, V. Woo, H.W. Rodbard, S. Linjawi, P. Poulsen, L.H. Damgaard, J.B. Buse; N. N. Trial Investigators, Efficacy and safety of a fixed-ratio combination of insulin degludec and liraglutide (IDegLira) compared with its components given alone: results of a phase 3, open-label, randomised, 26-week, treat-to-target trial in insulin-naive patients with type 2 diabetes. Lancet Diabetes Endocrinol. 2(11), 885–893 (2014)
-
(2014)
Lancet Diabetes Endocrinol.
, vol.2
, Issue.11
, pp. 885-893
-
-
Gough, S.C.1
Bode, B.2
Woo, V.3
Rodbard, H.W.4
Linjawi, S.5
Poulsen, P.6
Damgaard, L.H.7
Buse, J.B.8
-
3
-
-
84925489733
-
Management of hyperglycaemia in type 2 diabetes, 2015: a patient-centred approach. Update to a position statement of the American Diabetes Association and the European Association for the Study of Diabetes
-
PID: 25583541
-
S.E. Inzucchi, R.M. Bergenstal, J.B. Buse, M. Diamant, E. Ferrannini, M. Nauck, A.L. Peters, A. Tsapas, R. Wender, D.R. Matthews, Management of hyperglycaemia in type 2 diabetes, 2015: a patient-centred approach. Update to a position statement of the American Diabetes Association and the European Association for the Study of Diabetes. Diabetologia 58(3), 429–442 (2015)
-
(2015)
Diabetologia
, vol.58
, Issue.3
, pp. 429-442
-
-
Inzucchi, S.E.1
Bergenstal, R.M.2
Buse, J.B.3
Diamant, M.4
Ferrannini, E.5
Nauck, M.6
Peters, A.L.7
Tsapas, A.8
Wender, R.9
Matthews, D.R.10
-
4
-
-
85019774879
-
-
European Medicines Agency. Xultophy. Summary of product characteristics. http://www.ema.europa.eu/docs/en_GB/document_library/EPAR_-_Product_Information/human/002647/WC500177657.pdf. Accessed 15 Mar 2017
-
Xultophy. Summary of product characteristics
-
-
-
7
-
-
85019778896
-
-
® 100/3.6 (insulin degludec and liraglutide injection). http://press.novonordisk-us.com/2016-11-21-Novo-Nordisk-Receives-FDA-Approval-for-Xultophy-100-3-6-insulin-degludec-and-liraglutide-injection. Accessed 15 Mar 2017
-
® 100/3.6 (insulin degludec and liraglutide injection)
-
-
-
8
-
-
69149107727
-
The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration
-
PID: 19622512
-
A. Liberati, D.G. Altman, J. Tetzlaff, C. Mulrow, P.C. Gotzsche, J.P. Ioannidis, M. Clarke, P.J. Devereaux, J. Kleijnen, D. Moher, The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration. Ann. Intern. Med. 151(4), W65–W94 (2009)
-
(2009)
Ann. Intern. Med.
, vol.151
, Issue.4
, pp. W65-W94
-
-
Liberati, A.1
Altman, D.G.2
Tetzlaff, J.3
Mulrow, C.4
Gotzsche, P.C.5
Ioannidis, J.P.6
Clarke, M.7
Devereaux, P.J.8
Kleijnen, J.9
Moher, D.10
-
9
-
-
84883710616
-
J. Glanville Chapter 6: searching for studies. in Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0, ed
-
C. Lefebvre E. Manheimer J. Glanville Chapter 6: searching for studies. in Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0, ed. By The Cochrane Collaboration (The Cochrane Collaboration, 2011)
-
(2011)
By The Cochrane Collaboration (The Cochrane Collaboration
-
-
Lefebvre, C.1
Manheimer, E.2
-
10
-
-
84870715654
-
-
Scottish Intercollegiate Guidelines Network. Search filters. http://www.sign.ac.uk/methodology/filters.html. Accessed 15 Mar 2017
-
Search filters
-
-
-
11
-
-
84859001212
-
The Cochrane Collaboration’s tool for assessing risk of bias in randomised trials
-
PID: 22008217
-
J.P. Higgins, D.G. Altman, P.C. Gotzsche, P. Juni, D. Moher, A.D. Oxman, J. Savovic, K.F. Schulz, L. Weeks, J.A. Sterne; Cochrane Bias Methods Group, Cochrane Statistical Methods Group, The Cochrane Collaboration’s tool for assessing risk of bias in randomised trials. BMJ 343, d5928 (2011)
-
(2011)
BMJ
, vol.343
, pp. d5928
-
-
Higgins, J.P.1
Altman, D.G.2
Gotzsche, P.C.3
Juni, P.4
Moher, D.5
Oxman, A.D.6
Savovic, J.7
Schulz, K.F.8
Weeks, L.9
Sterne, J.A.10
-
12
-
-
0022992740
-
Meta-analysis in clinical trials
-
COI: 1:STN:280:DyaL2s7gsVamtA%3D%3D, PID: 3802833
-
R. DerSimonian, N. Laird, Meta-analysis in clinical trials. Control. Clin. Trials 7(3), 177–188 (1986)
-
(1986)
Control. Clin. Trials
, vol.7
, Issue.3
, pp. 177-188
-
-
DerSimonian, R.1
Laird, N.2
-
13
-
-
84959801619
-
Statistical aspects of the analysis of data from retrospective studies of disease
-
COI: 1:STN:280:DyaG1M%2FosVOhtQ%3D%3D, PID: 13655060
-
N. Mantel, W. Haenszel, Statistical aspects of the analysis of data from retrospective studies of disease. J. Natl Cancer Inst. 22(4), 719–748 (1959)
-
(1959)
J. Natl Cancer Inst.
, vol.22
, Issue.4
, pp. 719-748
-
-
Mantel, N.1
Haenszel, W.2
-
14
-
-
84994235673
-
Efficacy and safety of LixiLan, a titratable fixed-ratio combination of insulin glargine plus lixisenatide in type 2 diabetes inadequately controlled on basal insulin and metformin: the LixiLan-L randomized trial
-
PID: 27650977
-
V.R. Aroda, J. Rosenstock, C. Wysham, J. Unger, D. Bellido, G. Gonzalez-Galvez, A. Takami, H. Guo, E. Niemoeller, E. Souhami, R.M. Bergenstal, L. LixiLan; Trial Investigators, Efficacy and safety of LixiLan, a titratable fixed-ratio combination of insulin glargine plus lixisenatide in type 2 diabetes inadequately controlled on basal insulin and metformin: the LixiLan-L randomized trial. Diabetes Care 39(11), 1972–1980 (2016)
-
(2016)
Diabetes Care
, vol.39
, Issue.11
, pp. 1972-1980
-
-
Aroda, V.R.1
Rosenstock, J.2
Wysham, C.3
Unger, J.4
Bellido, D.5
Gonzalez-Galvez, G.6
Takami, A.7
Guo, H.8
Niemoeller, E.9
Souhami, E.10
Bergenstal, R.M.11
LixiLan, L.12
-
15
-
-
84910049684
-
Contribution of liraglutide in the fixed-ratio combination of insulin degludec and liraglutide (IDegLira)
-
COI: 1:CAS:528:DC%2BC2cXitVWltbfM, PID: 25114296
-
J.B. Buse, T. Vilsboll, J. Thurman, T.C. Blevins, I.H. Langbakke, S.G. Bottcher, H.W. Rodbard; N. N. Trial Investigators, Contribution of liraglutide in the fixed-ratio combination of insulin degludec and liraglutide (IDegLira). Diabetes Care 37(11), 2926–2933 (2014)
-
(2014)
Diabetes Care
, vol.37
, Issue.11
, pp. 2926-2933
-
-
Buse, J.B.1
Vilsboll, T.2
Thurman, J.3
Blevins, T.C.4
Langbakke, I.H.5
Bottcher, S.G.6
Rodbard, H.W.7
-
16
-
-
84942296569
-
One-year efficacy and safety of a fixed combination of insulin degludec and liraglutide in patients with type 2 diabetes: results of a 26-week extension to a 26-week main trial
-
COI: 1:CAS:528:DC%2BC2MXhsF2rur7E, PID: 25980900
-
S.C. Gough, B.W. Bode, V.C. Woo, H.W. Rodbard, S. Linjawi, M. Zacho, P.D. Reiter, J.B. Buse, One-year efficacy and safety of a fixed combination of insulin degludec and liraglutide in patients with type 2 diabetes: results of a 26-week extension to a 26-week main trial. Diabetes Obes. Metab. 17(10), 965–973 (2015)
-
(2015)
Diabetes Obes. Metab.
, vol.17
, Issue.10
, pp. 965-973
-
-
Gough, S.C.1
Bode, B.W.2
Woo, V.C.3
Rodbard, H.W.4
Linjawi, S.5
Zacho, M.6
Reiter, P.D.7
Buse, J.B.8
-
17
-
-
84959284398
-
Effect of insulin glargine up-titration vs insulin degludec/liraglutide on glycated hemoglobin levels in patients with uncontrolled type 2 diabetes: the DUAL V randomized clinical trial
-
COI: 1:CAS:528:DC%2BC28XhtFGqsbjE, PID: 26934259
-
I. Lingvay, F.P. Manghi, P. Garcia-Hernandez, P. Norwood, L. Lehmann, M.J. Tarp-Johansen, J.B. Buse; Dual V Investigators, Effect of insulin glargine up-titration vs insulin degludec/liraglutide on glycated hemoglobin levels in patients with uncontrolled type 2 diabetes: the DUAL V randomized clinical trial. JAMA 315(9), 898–907 (2016)
-
(2016)
JAMA
, vol.315
, Issue.9
, pp. 898-907
-
-
Lingvay, I.1
Manghi, F.P.2
Garcia-Hernandez, P.3
Norwood, P.4
Lehmann, L.5
Tarp-Johansen, M.J.6
Buse, J.B.7
Dual, V.8
-
18
-
-
85012159492
-
The efficacy of IDegLira (insulin degludec/liraglutide combination) in adults with type 2 diabetes inadequately controlled with a GLP-1 receptor agonist and oral therapy: DUAL III randomized clinical trial
-
COI: 1:CAS:528:DC%2BC28XitV2mt77K, PID: 27943107
-
S. Linjawi, B.W. Bode, L.B. Chaykin, J.P. Courreges, Y. Handelsman, L.M. Lehmann, A. Mishra, R.W. Simpson, The efficacy of IDegLira (insulin degludec/liraglutide combination) in adults with type 2 diabetes inadequately controlled with a GLP-1 receptor agonist and oral therapy: DUAL III randomized clinical trial. Diabetes Ther. 8(1), 101–114 (2017)
-
(2017)
Diabetes Ther.
, vol.8
, Issue.1
, pp. 101-114
-
-
Linjawi, S.1
Bode, B.W.2
Chaykin, L.B.3
Courreges, J.P.4
Handelsman, Y.5
Lehmann, L.M.6
Mishra, A.7
Simpson, R.W.8
-
19
-
-
84995543386
-
Safety and efficacy of insulin degludec/liraglutide (IDegLira) added to sulphonylurea alone or to sulphonylurea and metformin in insulin-naive people with type 2 diabetes: the DUAL IV trial
-
COI: 1:CAS:528:DC%2BC2sXht1Whsb0%3D, PID: 27589252
-
H.W. Rodbard, B.W. Bode, S.B. Harris, L. Rose, L. Lehmann, H. Jarlov, J. Thurman; Dual Action of Liraglutide and insulin degludec (DUAL) IV trial investigators, Safety and efficacy of insulin degludec/liraglutide (IDegLira) added to sulphonylurea alone or to sulphonylurea and metformin in insulin-naive people with type 2 diabetes: the DUAL IV trial. Diabet. Med. 34(2), 189–196 (2017)
-
(2017)
Diabet. Med.
, vol.34
, Issue.2
, pp. 189-196
-
-
Rodbard, H.W.1
Bode, B.W.2
Harris, S.B.3
Rose, L.4
Lehmann, L.5
Jarlov, H.6
Thurman, J.7
-
20
-
-
84982820694
-
Efficacy and safety of LixiLan, a titratable fixed-ratio combination of lixisenatide and insulin glargine, versus insulin glargine in type 2 diabetes inadequately controlled on metformin monotherapy: the LixiLan Proof-of-Concept randomized trial
-
PID: 27284114
-
J. Rosenstock, M. Diamant, V.R. Aroda, L. Silvestre, E. Souhami, T. Zhou, R. Perfetti, V. Fonseca; LixiLan PoC Study Group, Efficacy and safety of LixiLan, a titratable fixed-ratio combination of lixisenatide and insulin glargine, versus insulin glargine in type 2 diabetes inadequately controlled on metformin monotherapy: the LixiLan Proof-of-Concept randomized trial. Diabetes Care 39(9), 1579–1586 (2016)
-
(2016)
Diabetes Care
, vol.39
, Issue.9
, pp. 1579-1586
-
-
Rosenstock, J.1
Diamant, M.2
Aroda, V.R.3
Silvestre, L.4
Souhami, E.5
Zhou, T.6
Perfetti, R.7
Fonseca, V.8
-
21
-
-
84994234273
-
Benefits of LixiLan, a titratable fixed-ratio combination of insulin glargine plus lixisenatide, versus insulin glargine and lixisenatide monocomponents in type 2 diabetes inadequately controlled on oral agents: the LixiLan-O randomized trial
-
PID: 27527848
-
J. Rosenstock, R. Aronson, G. Grunberger, M. Hanefeld, P. Piatti, P. Serusclat, X. Cheng, T. Zhou, E. Niemoeller, E. Souhami, M. Davies; LixiLan-O Trial Investigators, Benefits of LixiLan, a titratable fixed-ratio combination of insulin glargine plus lixisenatide, versus insulin glargine and lixisenatide monocomponents in type 2 diabetes inadequately controlled on oral agents: the LixiLan-O randomized trial. Diabetes Care 39(11), 2026–2035 (2016)
-
(2016)
Diabetes Care
, vol.39
, Issue.11
, pp. 2026-2035
-
-
Rosenstock, J.1
Aronson, R.2
Grunberger, G.3
Hanefeld, M.4
Piatti, P.5
Serusclat, P.6
Cheng, X.7
Zhou, T.8
Niemoeller, E.9
Souhami, E.10
Davies, M.11
LixiLan, O.12
-
22
-
-
84949213902
-
IDegLira versus alternative intensification strategies in patients with type 2 diabetes inadequately controlled on basal insulin therapy
-
COI: 1:CAS:528:DC%2BC2MXhvFWlsLvP, PID: 26582052
-
N. Freemantle, M. Mamdani, T. Vilsboll, J.H. Kongso, K. Kvist, S.C. Bain, IDegLira versus alternative intensification strategies in patients with type 2 diabetes inadequately controlled on basal insulin therapy. Diabetes Ther. 6(4), 573–591 (2015)
-
(2015)
Diabetes Ther.
, vol.6
, Issue.4
, pp. 573-591
-
-
Freemantle, N.1
Mamdani, M.2
Vilsboll, T.3
Kongso, J.H.4
Kvist, K.5
Bain, S.C.6
-
23
-
-
84979231627
-
Cost effectiveness of IDegLira vs. alternative basal insulin intensification therapies in patients with type 2 diabetes mellitus uncontrolled on basal insulin in a UK setting
-
PID: 27438706
-
M.J. Davies, D. Glah, B. Chubb, G. Konidaris, P. McEwan, Cost effectiveness of IDegLira vs. alternative basal insulin intensification therapies in patients with type 2 diabetes mellitus uncontrolled on basal insulin in a UK setting. Pharmacoeconomics 34(9), 953–966 (2016)
-
(2016)
Pharmacoeconomics
, vol.34
, Issue.9
, pp. 953-966
-
-
Davies, M.J.1
Glah, D.2
Chubb, B.3
Konidaris, G.4
McEwan, P.5
-
25
-
-
84882243403
-
Handling of rescue and missing data affects synthesis and interpretation of evidence: the sodium-glucose cotransporter 2 inhibitor example
-
PID: 24026261
-
C.B. Stack, A.R. Localio, M.E. Griswold, S.N. Goodman, C.D. Mulrow, Handling of rescue and missing data affects synthesis and interpretation of evidence: the sodium-glucose cotransporter 2 inhibitor example. Ann. Intern. Med. 159(4), 285–288 (2013)
-
(2013)
Ann. Intern. Med.
, vol.159
, Issue.4
, pp. 285-288
-
-
Stack, C.B.1
Localio, A.R.2
Griswold, M.E.3
Goodman, S.N.4
Mulrow, C.D.5
-
27
-
-
84930588033
-
Glucagon-like polypeptide agonists in type 2 diabetes mellitus: efficacy and tolerability, a balance
-
COI: 1:CAS:528:DC%2BC2MXhtlKrtLrK, PID: 26137215
-
S.H. Tella, M.S. Rendell, Glucagon-like polypeptide agonists in type 2 diabetes mellitus: efficacy and tolerability, a balance. Ther. Adv. Endocrinol. Metab. 6(3), 109–134 (2015)
-
(2015)
Ther. Adv. Endocrinol. Metab.
, vol.6
, Issue.3
, pp. 109-134
-
-
Tella, S.H.1
Rendell, M.S.2
|